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Gene: Ddah1 (dimethylarginine dimethylaminohydrolase 1) Rattus norvegicus
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Symbol: Ddah1
Name: dimethylarginine dimethylaminohydrolase 1
Description: Exhibits amino acid binding activity and dimethylargininase activity. Involved in arginine metabolic process; positive regulation of angiogenesis; and positive regulation of nitric oxide biosynthetic process. Human ortholog(s) of this gene implicated in cardiovascular system disease and hypertension. Orthologous to human DDAH1 (dimethylarginine dimethylaminohydrolase 1); INTERACTS WITH 1-nitropropane; 17alpha-ethynylestradiol; 2,3,4,7,8-Pentachlorodibenzofuran.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: DDAH-1; DDAHI; dimethylargininase-1; n(G),N(G)-dimethylarginine dimethylaminohydrolase 1; NG,NG dimethylarginine dimethylaminohydrolase; NGNG dimethylarginine dimethylaminohydrolase
Orthologs:
Homo sapiens (human) : DDAH1 (dimethylarginine dimethylaminohydrolase 1)  HGNC  Alliance
Mus musculus (house mouse) : Ddah1 (dimethylarginine dimethylaminohydrolase 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ddah1 (dimethylarginine dimethylaminohydrolase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : DDAH1 (dimethylarginine dimethylaminohydrolase 1)
Canis lupus familiaris (dog) : DDAH1 (dimethylarginine dimethylaminohydrolase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ddah1 (dimethylarginine dimethylaminohydrolase 1)
Sus scrofa (pig) : DDAH1 (dimethylarginine dimethylaminohydrolase 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: suggests misassembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02251,634,368 - 251,766,009 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2251,634,431 - 251,766,014 (+)Ensembl
Rnor_5.02270,160,842 - 270,289,319 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42243,932,221 - 244,069,832 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12243,918,960 - 244,056,573 (+)NCBI
Celera2226,655,820 - 226,787,619 (+)NCBICelera
Cytogenetic Map2q44NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Ddah1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 70968
Created: 2002-07-09
Species: Rattus norvegicus
Last Modified: 2019-10-29
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.