Gene: Abat (4-aminobutyrate aminotransferase) Rattus norvegicus
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Symbol: Abat
Name: 4-aminobutyrate aminotransferase
Description: ENCODES a protein that exhibits 4-aminobutyrate transaminase activity; protein homodimerization activity (ortholog); pyridoxal phosphate binding (ortholog); INVOLVED IN aging; cerebellum development; copulation; PARTICIPATES IN 2-hydroxyglutaric aciduria pathway; 3-hydroxy-3-methylglutaryl-CoA lyase deficiency pathway; 3-hydroxyisobutyric aciduria pathway; ASSOCIATED WITH Anorexia; Cocaine-Related Disorders; Diabetes Mellitus, Experimental ; FOUND IN mitochondrial matrix; mitochondrion; neuron projection; INTERACTS WITH 1,3-dinitrobenzene; 1-bromopropane; 1-naphthyl isothiocyanate
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: (S)-3-amino-2-methylpropionate transaminase; 4-aminobutyrate aminotransferase, mitochondrial; beta-AlaAT; GABA aminotransferase; GABA transaminase; GABA-AT; GABA-T; Gabat; gamma-amino-N-butyrate transaminase; L-AIBAT; MGC93392
Orthologs:
Homo sapiens (human) : ABAT (4-aminobutyrate aminotransferase)  HGNC  Alliance
Mus musculus (house mouse) : Abat (4-aminobutyrate aminotransferase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Abat (4-aminobutyrate aminotransferase)
Pan paniscus (bonobo/pygmy chimpanzee) : ABAT (4-aminobutyrate aminotransferase)
Canis lupus familiaris (dog) : ABAT (4-aminobutyrate aminotransferase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Abat (4-aminobutyrate aminotransferase)
more info ...
Allele / Splice: AbatTn(sb-T2/Bart3)2.163Mcwi  
Genetic Models: F344-AbatTn(sb-T2/Bart3)2.163Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0107,093,406 - 7,200,439 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0105,894,187 - 6,002,068 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4107,040,725 - 7,137,154 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1107,040,724 - 7,137,154 (-)NCBI
Celera105,995,207 - 6,088,218 (-)NCBICelera
Cytogenetic Map10q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Abat
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 620948
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2018-08-08
Status: ACTIVE