Gene: Chd8 (chromodomain helicase DNA binding protein 8) Rattus norvegicus
Symbol: Chd8
Name: chromodomain helicase DNA binding protein 8
Description: ENCODES a protein that exhibits armadillo repeat domain binding; beta-catenin binding; ATP binding (ortholog); INVOLVED IN negative regulation of canonical Wnt signaling pathway; negative regulation of transcription, DNA-templated; negative regulation of Wnt signaling pathway; PARTICIPATES IN Wnt signaling pathway; ASSOCIATED WITH autism spectrum disorder (ortholog); autistic disorder (ortholog); Gastrointestinal Diseases (ortholog); FOUND IN nucleus; protein-containing complex; MLL1 complex (ortholog); INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; ammonium chloride
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: ATP-dependent helicase CHD8; axis duplication inhibitor; beta-catenin binding protein; CHD-8; chromodomain-helicase-DNA-binding protein 8; duplin; Loc65027
Homo sapiens (human) : CHD8 (chromodomain helicase DNA binding protein 8)  HGNC  Alliance
Mus musculus (house mouse) : Chd8 (chromodomain helicase DNA binding protein 8)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Chd8 (chromodomain helicase DNA binding protein 8)
Pan paniscus (bonobo/pygmy chimpanzee) : CHD8 (chromodomain helicase DNA binding protein 8)
Canis lupus familiaris (dog) : CHD8 (chromodomain helicase DNA binding protein 8)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Chd8 (chromodomain helicase DNA binding protein 8)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01528,612,932 - 28,672,574 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01532,423,198 - 32,482,762 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41527,642,767 - 27,704,443 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11527,684,891 - 27,696,816 (-)NCBI
Celera1525,209,591 - 25,269,314 (-)NCBICelera
Cytogenetic Map15p14NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Chd8
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 620696
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2018-10-09
Status: ACTIVE