Strain: F344-Ttnem1Sage

Symbol: F344-Ttnem1Sage
Strain: F344-Ttnem1
Substrain: Sage
Ontology ID: RS:0004302
Alleles: Ttnem1Sage
Also known as: TTNtvA rat; F344-Ttnem1Sage
Type: mutant
Source: Duke-National University of Singapore, Singapore
Origin: These ZFN mutant rats were produced by injecting zinc finger nuclease targeting rat Ttn into F344 embryos. The zinc-finger nuclease mediated genome editing system created a 12-bp deletion and a 2-bp insertion (TA) at 228,608-228,619 (Rnor_5.0) to introduce a stop codon in exon 303, corresponding to exon 327 in the human sequence.
Last Known Status: Unknown (as of 2016-11-28)
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0363,565,160 - 63,837,815RGD_MAPPER_PIPELINERnor6.0
Rnor_5.0370,138,896 - 70,408,647RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.4359,404,023 - 59,665,308RGD_MAPPER_PIPELINERGSC3.4

Phenotype Annotations
Experimental Data Annotations
References - curated
RGD Disease Portals


Additional Information

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Strain Registration

RGD Object Information
RGD ID: 11565826
Created: 2016-11-28
Species: Rattus norvegicus
Last Modified: 2016-11-28
Status: ACTIVE