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Gene: Muc1 (mucin 1, cell surface associated) Rattus norvegicus
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Symbol: Muc1
Name: mucin 1, cell surface associated
Description: Predicted to have RNA polymerase II proximal promoter sequence-specific DNA binding activity; p53 binding activity; and transcription coregulator activity. Involved in several processes, including cellular response to retinoic acid; female pregnancy; and response to hypoxia. Localizes to the apical plasma membrane and cytoplasm. Biomarker of cholangiocarcinoma; chronic obstructive pulmonary disease; cystic fibrosis; and otitis media. Human ortholog(s) of this gene implicated in biliary tract benign neoplasm; breast cancer; dry eye syndrome; mucinous adenocarcinoma; and pancreatic cancer (multiple). Orthologous to human MUC1 (mucin 1, cell surface associated); PARTICIPATES IN p53 signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2-acetamidofluorene.
Type: protein-coding
RefSeq Status: MODEL
Also known as: MGC188069; mucin 1; mucin 1, transmembrane; mucin-1; Mucin1
Orthologs:
Homo sapiens (human) : MUC1 (mucin 1, cell surface associated)  HGNC  Alliance
Mus musculus (house mouse) : Muc1 (mucin 1, transmembrane)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Muc1 (mucin 1, cell surface associated)
Pan paniscus (bonobo/pygmy chimpanzee) : MUC1 (mucin 1, cell surface associated)
Canis lupus familiaris (dog) : MUC1 (mucin 1, cell surface associated)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Muc1 (mucin 1, cell surface associated)
Sus scrofa (pig) : MUC1 (mucin 1, cell surface associated)
more info ...
Allele / Splice: Muc1em1Mcwi  
Genetic Models: FHH-Muc1em1Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02188,543,137 - 188,547,874 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2188,543,137 - 188,547,874 (+)Ensembl
Rnor_5.02207,957,206 - 207,962,396 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42181,399,482 - 181,403,640 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12181,352,002 - 181,353,687 (+)NCBI
Celera2168,578,421 - 168,583,038 (+)NCBICelera
Cytogenetic Map2q34NCBI
RH 3.4 Map21155.0RGD
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Muc1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3122
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.