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Gene: Csf1 (colony stimulating factor 1) Rattus norvegicus
Symbol: Csf1
Name: colony stimulating factor 1
RGD ID: 621063
Description: Exhibits identical protein binding activity. Involved in several processes, including myeloid leukocyte differentiation; odontogenesis; and ossification. Localizes to extracellular space. Used to study anti-basement membrane glomerulonephritis; malignant glioma; and osteopetrosis. Biomarker of systemic scleroderma. Human ortholog(s) of this gene implicated in interstitial cystitis. Orthologous to human CSF1 (colony stimulating factor 1); PARTICIPATES IN cytokine mediated signaling pathway; rheumatoid arthritis pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene.
Type: protein-coding
Also known as: colony stimulating factor 1 (macrophage); colony stimulating factor 1(macrophage); CSF-1; macrophage colony-stimulating factor 1; MCSF
Homo sapiens (human) : CSF1 (colony stimulating factor 1)  HGNC  Alliance
Mus musculus (house mouse) : Csf1 (colony stimulating factor 1 (macrophage))  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Csf1 (colony stimulating factor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : CSF1 (colony stimulating factor 1)
Canis lupus familiaris (dog) : CSF1 (colony stimulating factor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Csf1 (colony stimulating factor 1)
Sus scrofa (pig) : CSF1 (colony stimulating factor 1)
Chlorocebus sabaeus (African green monkey) : CSF1 (colony stimulating factor 1)
Heterocephalus glaber (naked mole-rat) : Csf1 (colony stimulating factor 1)
more info ...
Allele / Splice: Csf1tl  
Genetic Models: F344tl
Is Marker For: Strains:   LEW-tl   LEW-tl.BN-(D2Arb16-D2Wox8)   F344tl  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: suggests misassembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.02210,522,370 - 210,550,546 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2210,522,375 - 210,550,560 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02229,989,430 - 230,017,945 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42203,292,765 - 203,307,968 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12203,255,518 - 203,270,701 (-)NCBI
Celera2188,024,644 - 188,043,645 (-)NCBICelera
Cytogenetic Map2q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Related Rat Strains
Genetic Models
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Csf1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 621063
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-09-01
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.