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Gene: Fxn (frataxin) Rattus norvegicus
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Symbol: Fxn
Name: frataxin
Description: Exhibits enzyme binding activity. Involved in positive regulation of axon extension; response to drug; and response to organic cyclic compound. Localizes to the mitochondrion. Human ortholog(s) of this gene implicated in Friedreich ataxia; Friedreich ataxia 1; and type 2 diabetes mellitus. Orthologous to human FXN (frataxin); PARTICIPATES IN hypoxia inducible factor pathway; INTERACTS WITH 2,4,6-trinitrotoluene; bisphenol A; decabromodiphenyl ether.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: frataxin, mitochondrial; LOC499335; RGD1565754; similar to frataxin
Orthologs:
Homo sapiens (human) : FXN (frataxin)  HGNC  Alliance
Mus musculus (house mouse) : Fxn (frataxin)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fxn (frataxin)
Pan paniscus (bonobo/pygmy chimpanzee) : FXN (frataxin)
Canis lupus familiaris (dog) : FXN (frataxin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fxn (frataxin)
Sus scrofa (pig) : FXN (frataxin)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01242,123,975 - 242,152,834 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1242,123,975 - 242,152,834 (-)Ensembl
Rnor_5.01249,419,972 - 249,426,597 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.01249,400,435 - 249,400,757 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41227,647,092 - 227,671,081 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1219,085,510 - 219,108,749 (-)NCBICelera
Cytogenetic Map1q51NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Fxn
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1565754
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.