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Gene: Ndufc2 (NADH:ubiquinone oxidoreductase subunit C2) Rattus norvegicus
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Symbol: Ndufc2
Name: NADH:ubiquinone oxidoreductase subunit C2
RGD ID: 1307511
Description: Predicted to have NADH dehydrogenase (ubiquinone) activity. Involved in several processes, including mitochondrial respiratory chain complex I assembly; negative regulation of NIK/NF-kappaB signaling; and positive regulation of mitochondrial membrane potential. Predicted to localize to mitochondrial respiratory chain complex I. Orthologous to several human genes including NDUFC2 (NADH:ubiquinone oxidoreductase subunit C2); PARTICIPATES IN Alzheimer's disease pathway; Huntington's disease pathway; oxidative phosphorylation pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC293130; MGC109009; NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2; NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa; NADH dehydrogenase [ubiquinone] 1 subunit C2
Orthologs:
Homo sapiens (human) : NDUFC2 (NADH:ubiquinone oxidoreductase subunit C2)  HGNC  Alliance
Mus musculus (house mouse) : Ndufc2 (NADH:ubiquinone oxidoreductase subunit C2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ndufc2 (NADH:ubiquinone oxidoreductase subunit C2)
Pan paniscus (bonobo/pygmy chimpanzee) : NDUFC2 (NADH:ubiquinone oxidoreductase subunit C2)
Canis lupus familiaris (dog) : NDUFC2 (NADH:ubiquinone oxidoreductase subunit C2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ndufc2 (NADH:ubiquinone oxidoreductase subunit C2)
Sus scrofa (pig) : NDUFC2 (NADH:ubiquinone oxidoreductase subunit C2)
Chlorocebus sabaeus (African green monkey) : NDUFC2 (NADH:ubiquinone oxidoreductase subunit C2)
Heterocephalus glaber (naked mole-rat) : Ndufc2 (NADH:ubiquinone oxidoreductase subunit C2)
more info ...
Allele / Splice: Ndufc2em1Mcwi   Ndufc2em2Mcwi  
Genetic Models: SHR-Ndufc2em1Mcwi SHR-Ndufc2em1Mcwi-/+ SHR-Ndufc2em2Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01162,369,801 - 162,376,024 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1162,369,801 - 162,376,023 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01168,576,274 - 168,582,497 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41154,635,889 - 154,642,112 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11154,714,294 - 154,720,517 (+)NCBI
Celera1149,811,897 - 149,818,120 (+)NCBICelera
Cytogenetic Map1q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Ndufc2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1307511
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.