Gene: Dcc (DCC netrin 1 receptor) Rattus norvegicus
Symbol: Dcc
Name: DCC netrin 1 receptor
Description: ENCODES a protein that exhibits identical protein binding; netrin receptor activity; transcription coactivator activity; INVOLVED IN axon guidance; positive regulation of ERK1 and ERK2 cascade; positive regulation of neuron projection development; PARTICIPATES IN colorectal cancer pathway; ASSOCIATED WITH Experimental Autoimmune Neuritis; Reperfusion Injury; Spinal Cord Injuries; FOUND IN axon; growth cone membrane; membrane raft; INTERACTS WITH 6-propyl-2-thiouracil; androgen antagonist; bis(2-ethylhexyl) phthalate
Type: protein-coding
Also known as: colorectal tumor suppressor; Deleted in colcorectal cancer (rat homolog); deleted in colorectal carcinoma; netrin receptor DCC; putative colorectal tumor suppressor; tumor suppressor protein DCC
Homo sapiens (human) : DCC (DCC netrin 1 receptor)  HGNC  Alliance
Mus musculus (house mouse) : Dcc (deleted in colorectal carcinoma)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dcc (DCC netrin 1 receptor)
Pan paniscus (bonobo/pygmy chimpanzee) : DCC (DCC netrin 1 receptor)
Canis lupus familiaris (dog) : DCC (DCC netrin 1 receptor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dcc (DCC netrin 1 receptor)
more info ...
Allele / Splice: DccTn(sb-T2/Bart3)2.205Mcwi  
Genetic Models: F344-DccTn(sb-T2/Bart3)2.205Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01866,518,213 - 67,629,801 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01865,688,901 - 66,793,126 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41868,026,795 - 69,140,741 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11868,099,995 - 69,213,942 (-)NCBI
Celera1862,907,666 - 64,001,277 (-)NCBICelera
Cytogenetic Map18q12.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Dcc
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2492
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2018-05-29
Status: ACTIVE