Bw187 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL Registration

QTL: Bw187 (Body weight QTL 187) Rattus norvegicus

Symbol: Bw187
Name: Body weight QTL 187
RGD ID: 12880368
Previously known as: BpcakmC18QTL3
Trait: body mass   (VT:0001259)    
Measurement Type: body weight   (CMO:0000012)    
LOD Score: Not Available
P Value: 0.045
Variance: Not Available
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81833,379,158 - 78,379,158RGD_MAPPER_PIPELINE
mRatBN7.21852,539,763 - 76,104,388RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01854,108,375 - 79,575,348RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01853,346,348 - 78,640,858RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.41854,856,551 - 79,195,912RGD_MAPPER_PIPELINERGSC3.4
Cross Type: Not Available
Strains Crossed: SS.LEW-(D18Rat61-D18Rat45)/Ayd 
JBrowse: View Region in Genome Browser (JBrowse)
Model




  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bw187Rathypertension  IAGP 1599557 RGD 

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bw187Ratabnormal body weight  IAGP 1599557 RGD 

Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bw187Ratbody weight  IDA 1599557 RGD 

Experimental Condition
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bw187Ratcontrolled sodium content diet  IDA 1599557 RGD 

Measurement Method
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bw187Ratscale  IDA 1599557 RGD 

Rat Strain
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bw187RatSS.LEW-(D18Rat61-D18Rat45)/Ayd  IEA 1599557 RGD 

Vertebrate Trait
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bw187Ratbody mass  IDA 1599557 RGD 


#
Reference Title
Reference Citation
1. Distinct quantitative trait loci for kidney, cardiac, and aortic mass dissociated from and associated with blood pressure in Dahl congenic rats. Duong C, etal., Mamm Genome. 2006 Dec;17(12):1147-61. Epub 2006 Dec 1.


1 to 20 of 314 rows
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
1312005Minar2membrane integral NOTCH2 associated receptor 2185253971452554465Rat
41282418LOC120098155uncharacterized LOC120098155185255029452553031Rat
1560819Chsy3chondroitin sulfate synthase 3185264435652901257Rat
7500552LOC102548951uncharacterized LOC102548951185343914553494664Rat
1359421Ifgga2l1interferon-gamma-inducible GTPase 2 like 1185376111853770183Rat
41389142Ifgga2l-ps2interferon-gamma-inducible GTPase 2 like, pseudogene 2185378908553794279Rat
1305184Ifgga4linterferon-gamma-inducible GTPase 4 like185383842653854858Rat
1565797Ifgga2l2interferon-gamma-inducible GTPase 2 like 2185387083853890135Rat
7748007Ifgga2l-ps1interferon-gamma-inducible GTPase 2 like, pseudogene 1185390703453909527Rat
628864Smim3small integral membrane protein 3185393001953982339Rat
71023Dctn4dynactin subunit 4185398235554009409Rat
1305770Rbm22RNA binding motif protein 22185401337454024182Rat
1594778Myoz3myozenin 3185402613354046151Rat
620668Synposynaptopodin185404829954106388Rat
41167261LOC120098275uncharacterized LOC120098275185412539654133520Rat
69303Ndst1N-deacetylase and N-sulfotransferase 1185413688754199545Rat
62025Rps14ribosomal protein S14185422785454232638Rat
2313Cd74CD74 molecule185425675754266003Rat
1309850Tcof1treacle ribosome biogenesis factor 1185426701554300324Rat
7546100LOC102550733uncharacterized LOC102550733185433675454348014Rat

1 to 20 of 314 rows
1 to 20 of 520 rows
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Expected Size
Chr
Start
Stop
Species
Match
10108D18Mgh11341185564260755642948Ratregion
10647D18Wox12140186037761560377755Ratregion
10648D18Wox13163186037759060377753Ratregion
10667D18Mit17117186076313260763249Ratregion
33856D18Mit10225186040871960408944Ratregion
33884D18Mit8147185979647859796643Ratregion
34043D18Mit16148186169831761698465Ratregion
34182D18Mgh3145186584495065845095Ratregion
34218D18Mgh2183185971223459712417Ratregion
34256D4Mgh18124186205711662057171Ratregion
34270D18Mgh6132186702536067025492Ratregion
34421D15Mgh10109187114739571147526Ratregion
37412D18Rat40154185933040959330563Ratregion
37514D18Rat43227186357104063571267Ratregion
37548D18Rat52195185853611658536311Ratregion
37568D18Rat55100185253976352539863Ratregion
37586D18Rat74172187518195575182127Ratregion
35282D18Rat5143187399714073997283Ratregion
36816D18Rat12234186938409269384326Ratregion
36954D18Rat6168187375435573754523Ratregion
1 to 20 of 520 rows

Flank 1: (D18Rat55)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21852,539,763 - 52,539,863 (+)MAPPER
Rnor_6.01854,108,375 - 54,108,474NCBI
Rnor_5.01853,346,348 - 53,346,447UniSTS
RGSC_v3.41854,856,552 - 54,856,651UniSTS
RGSC_v3.41854,856,551 - 54,856,651RGD
RGSC_v3.11854,928,784 - 54,928,883RGD
Celera1850,643,852 - 50,643,951UniSTS
RH 3.4 Map18497.9RGD
RH 3.4 Map18497.9UniSTS
RH 2.0 Map18411.9RGD
SHRSP x BN Map1822.7899RGD
FHH x ACI Map1831.46RGD
Cytogenetic Map18q12.1UniSTS
Flank 2: (D18Uia6)
Rat AssemblyChrPosition (strand)Source
GRCr81878,378,954 - 78,379,158 (+)Marker Load Pipeline
mRatBN7.21876,104,184 - 76,104,388 (+)MAPPER
Rnor_6.01879,575,145 - 79,575,348NCBI
Rnor_5.01878,640,655 - 78,640,858UniSTS
RGSC_v3.41879,195,708 - 79,195,908RGD
RGSC_v3.41879,195,709 - 79,195,912UniSTS
RGSC_v3.11879,268,981 - 79,269,181RGD
Celera1874,735,502 - 74,735,705UniSTS
Cytogenetic Map18 RGD


1 to 10 of 74 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1331733Bp233Blood pressure QTL 2333.97196arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)182479697779788953Rat
1358358Sradr6Stress Responsive Adrenal Weight QTL 62.49adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)181194429959330563Rat
1331730Scl27Serum cholesterol level QTL 273.826blood HDL cholesterol amount (VT:0000184)serum high density lipoprotein cholesterol level (CMO:0000361)185229287559796643Rat
1331741Bp232Blood pressure QTL 2323.59112arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)182137289383213037Rat
1331742Bp228Blood pressure QTL 2283.88752arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183135940859796643Rat
1298072Cia26Collagen induced arthritis QTL 263.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)185470976983828827Rat
1331736Bp227Blood pressure QTL 2272.791arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)184671876359796643Rat
1300125Rf26Renal function QTL 263.2urine potassium amount (VT:0010539)urine potassium excretion rate (CMO:0000761)185253986365844950Rat
631834Sach3Saccharin preference QTL 33.90.01consumption behavior trait (VT:0002069)calculated saccharin drink intake volume (CMO:0001600)185880568763636873Rat
6893683Bw110Body weight QTL 1102.70.002body mass (VT:0001259)body weight (CMO:0000012)184334502283828827Rat

1 to 10 of 74 rows



Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-05-16 Bw187  Body weight QTL 187  Bp403  Blood pressure QTL 403  Name updated 68913 APPROVED
2017-05-16 Bw187  Body weight QTL 187  Bp403  Blood pressure QTL 403  Symbol updated 68687 APPROVED

Note Type Note Reference
qtl_general number of animals used: 6 gender: male 1599557
qtl_general also affects kidney mass, blood pressure, heart left and right ventricle mass, aortic mass and cardiac mass 1599557
qtl_statistics_details software package used: ANOVA followed by Dunnett test in the SYSTAT 9 program 1599557
qtl_trait_method measurement method: selected males were weaned at 21 days of age, then fed a 2% NaCl diet starting from 35 days of age; at 14 weeks animals were weighed 1599557