Gene: Adrb2 (adrenoceptor beta 2) Rattus norvegicus
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Symbol: Adrb2
Name: adrenoceptor beta 2
Description: Exhibits several functions, including G-protein alpha-subunit binding activity, catecholamine binding activity, and signaling receptor binding activity; involved in several processes, including chemical synaptic transmission, positive regulation of transport, and regulation of blood pressure; localizes to several cellular components, including the caveola, intracellular organelle, and neuron projection; used to study several diseases, including cardiomyopathy (multiple), congestive heart failure, kidney disease (multiple), and lung disease (multiple); biomarker of several diseases, including acute kidney failure, artery disease (multiple), congestive heart failure, hypothyroidism, and polycystic ovary syndrome; orthologous to human ADRB2 (adrenoceptor beta 2); PARTICIPATES IN G protein mediated signaling pathway via Galphai family; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; epinephrine signaling pathway via adrenergic receptor beta; INTERACTS WITH (5-hydroxyindol-3-yl)acetic acid; (R)-adrenaline; (R)-noradrenaline.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Adrenergic beta 2- receptor surface; adrenergic receptor, beta 2; adrenergic, beta-2-, receptor, surface; adrenoceptor beta 2, surface; beta-2 adrenergic receptor; beta-2 adrenoceptor; beta-2 adrenoreceptor
Orthologs:
Homo sapiens (human) : ADRB2 (adrenoceptor beta 2)  HGNC  Alliance
Mus musculus (house mouse) : Adrb2 (adrenergic receptor, beta 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Adrb2 (adrenoceptor beta 2)
Pan paniscus (bonobo/pygmy chimpanzee) : ADRB2 (adrenoceptor beta 2)
Canis lupus familiaris (dog) : ADRB2 (adrenoceptor beta 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Adrb2 (adrenoceptor beta 2)
Sus scrofa (pig) : ADRB2 (adrenoceptor beta 2)
more info ...
Is Marker For: QTLs:   BpQTLcluster15  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01857,513,792 - 57,515,834 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01856,739,990 - 56,742,032 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41858,174,958 - 58,177,000 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11858,247,190 - 58,249,232 (-)NCBI
Celera1853,789,848 - 53,791,890 (-)NCBICelera
Cytogenetic Map18q12.1NCBI
RH 3.4 Map18542.9RGD
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Adrb2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2060
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.