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Gene: Atp8b1 (ATPase phospholipid transporting 8B1) Rattus norvegicus
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Symbol: Atp8b1
Name: ATPase phospholipid transporting 8B1
Description: Predicted to have aminophospholipid flippase activity and cardiolipin binding activity. Predicted to be involved in several processes, including nervous system development; phospholipid transport; and regulation of microvillus assembly. Localizes to the brush border membrane. Human ortholog(s) of this gene implicated in benign recurrent intrahepatic cholestasis 1; intrahepatic cholestasis; intrahepatic cholestasis of pregnancy 1; and progressive familial intrahepatic cholestasis 1. Orthologous to human ATP8B1 (ATPase phospholipid transporting 8B1); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 2,3,7,8-tetrachlorodibenzodioxine; acrylamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: ATPase, aminophospholipid transporter, class I, type 8B, member 1; ATPase, Class I, type 8B, member 1; LOC291555; phospholipid-transporting ATPase IC; probable phospholipid-transporting ATPase IC
Orthologs:
Homo sapiens (human) : ATP8B1 (ATPase phospholipid transporting 8B1)  HGNC  Alliance
Mus musculus (house mouse) : Atp8b1 (ATPase, class I, type 8B, member 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Atp8b1 (ATPase phospholipid transporting 8B1)
Pan paniscus (bonobo/pygmy chimpanzee) : ATP8B1 (ATPase phospholipid transporting 8B1)
Canis lupus familiaris (dog) : ATP8B1 (ATPase phospholipid transporting 8B1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Atp8b1 (ATPase phospholipid transporting 8B1)
Sus scrofa (pig) : ATP8B1 (ATPase phospholipid transporting 8B1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01860,013,388 - 60,152,920 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01859,223,547 - 59,362,294 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41860,748,738 - 60,829,650 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11860,822,079 - 60,960,656 (-)NCBI
Celera1856,155,326 - 56,236,232 (-)NCBICelera
Cytogenetic Map18q12.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Atp8b1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1308488
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.