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Gene: Atp8b1 (ATPase phospholipid transporting 8B1) Rattus norvegicus
Symbol: Atp8b1
Name: ATPase phospholipid transporting 8B1
RGD ID: 1308488
Description: Predicted to have aminophospholipid flippase activity and cardiolipin binding activity. Predicted to be involved in several processes, including drug transmembrane transport; lipid transport; and nervous system development. Localizes to brush border membrane. Human ortholog(s) of this gene implicated in benign recurrent intrahepatic cholestasis 1; intrahepatic cholestasis; intrahepatic cholestasis of pregnancy 1; and progressive familial intrahepatic cholestasis 1. Orthologous to human ATP8B1 (ATPase phospholipid transporting 8B1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; acetamide.
Type: protein-coding
Also known as: ATPase, aminophospholipid transporter, class I, type 8B, member 1; ATPase, Class I, type 8B, member 1; LOC291555; phospholipid-transporting ATPase IC; probable phospholipid-transporting ATPase IC
Homo sapiens (human) : ATP8B1 (ATPase phospholipid transporting 8B1)  HGNC  Alliance
Mus musculus (house mouse) : Atp8b1 (ATPase, class I, type 8B, member 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Atp8b1 (ATPase phospholipid transporting 8B1)
Pan paniscus (bonobo/pygmy chimpanzee) : ATP8B1 (ATPase phospholipid transporting 8B1)
Canis lupus familiaris (dog) : ATP8B1 (ATPase phospholipid transporting 8B1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Atp8b1 (ATPase phospholipid transporting 8B1)
Sus scrofa (pig) : ATP8B1 (ATPase phospholipid transporting 8B1)
Chlorocebus sabaeus (African green monkey) : ATP8B1 (ATPase phospholipid transporting 8B1)
Heterocephalus glaber (naked mole-rat) : Atp8b1 (ATPase phospholipid transporting 8B1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01860,013,388 - 60,152,920 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1860,013,382 - 60,095,354 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01859,223,547 - 59,362,294 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41860,748,738 - 60,829,650 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11860,822,079 - 60,960,656 (-)NCBI
Celera1856,155,326 - 56,236,232 (-)NCBICelera
Cytogenetic Map18q12.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Atp8b1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1308488
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.