Psmg2 (proteasome assembly chaperone 2)

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Gene: Psmg2 (proteasome assembly chaperone 2) Rattus norvegicus

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Symbol:

Psmg2

Name:

proteasome assembly chaperone 2

RGD ID:

1304867

Description:

Predicted to enable molecular adaptor activity. Predicted to be involved in chaperone-mediated protein complex assembly and proteasome assembly. Predicted to act upstream of or within mitotic spindle assembly checkpoint signaling and negative regulation of apoptotic process. Predicted to be part of protein folding chaperone complex. Predicted to be active in cytosol and nucleus. Human ortholog(s) of this gene implicated in proteosome-associated autoinflammatory syndrome 4. Orthologous to human PSMG2 (proteasome assembly chaperone 2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

LOC291539; proteasome (prosome, macropain) assembly chaperone 2; Tnfsf5ip1; tumor necrosis factor superfamily, member 5-induced protein 1

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	PSMG2 (proteasome assembly chaperone 2)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Psmg2 (proteasome (prosome, macropain) assembly chaperone 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Psmg2 (proteasome assembly chaperone 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	PSMG2 (proteasome assembly chaperone 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	PSMG2 (proteasome assembly chaperone 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Psmg2 (proteasome assembly chaperone 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	PSMG2 (proteasome assembly chaperone 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	PSMG2 (proteasome assembly chaperone 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Psmg2 (proteasome assembly chaperone 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	PSMG2 (proteasome assembly chaperone 2)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Psmg2 (proteasome (prosome, macropain) assembly chaperone 2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	psmg2 (proteasome (prosome, macropain) assembly chaperone 2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG12321	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Saccharomyces cerevisiae (baker's yeast):	ADD66	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OrthoFinder\|PANTHER)
Xenopus tropicalis (tropical clawed frog):	psmg2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	18	63,478,620 - 63,493,193 (+)	NCBI		GRCr8
mRatBN7.2	18	61,208,669 - 61,227,671 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	18	61,208,678 - 61,259,816 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	18	63,279,183 - 63,293,754 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	18	63,977,935 - 63,992,504 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	18	61,827,771 - 61,842,343 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	18	63,394,991 - 63,420,491 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	18	63,394,900 - 63,409,600 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	18	62,579,990 - 62,594,563 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	18	64,185,650 - 64,200,223 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	18	64,258,830 - 64,273,424 (+)	NCBI
Celera	18	59,314,858 - 59,329,453 (+)	NCBI		Celera
Cytogenetic Map	18	q12.1	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

chromosome 18p deletion syndrome (ISO)

Dwarfism (ISO)

dystonia (ISO)

intellectual disability (ISO)

proteosome-associated autoinflammatory syndrome 4 (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(S)-nicotine (ISO)

1,2-dimethylhydrazine (ISO)

1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (ISO)

17alpha-ethynylestradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4-dinitrotoluene (EXP)

2,6-dinitrotoluene (EXP)

2-hydroxypropanoic acid (ISO)

3-isobutyl-1-methyl-7H-xanthine (ISO)

acrylamide (EXP)

aflatoxin B1 (ISO)

alpha-Zearalanol (EXP)

amitrole (EXP)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

bisphenol A (EXP,ISO)

chlorpyrifos (ISO)

chromium(6+) (ISO)

crocidolite asbestos (ISO)

dexamethasone (ISO)

Dibutyl phosphate (ISO)

dibutyl phthalate (ISO)

fenthion (ISO)

flutamide (EXP)

folic acid (ISO)

indometacin (ISO)

ivermectin (ISO)

methidathion (ISO)

nefazodone (EXP)

nicotine (ISO)

nimesulide (EXP)

ozone (ISO)

paracetamol (EXP,ISO)

perfluorooctanoic acid (EXP)

phenobarbital (ISO)

pirinixic acid (ISO)

rac-lactic acid (ISO)

sodium arsenite (ISO)

Soman (EXP)

tetrachloromethane (EXP)

thapsigargin (ISO)

titanium dioxide (ISO)

trimellitic anhydride (ISO)

valproic acid (ISO)

zearalenone (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

chaperone-mediated protein complex assembly (ISO)

mitotic spindle assembly checkpoint signaling (ISO)

negative regulation of apoptotic process (ISO)

proteasome assembly (IBA)

regulation of cell cycle (ISO)

Cellular Component

cytosol (IBA)

nucleus (IBA,ISO)

protein folding chaperone complex (ISO)

Molecular Function

molecular adaptor activity (ISO)

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:8889548	PMID:12147697	PMID:16251969	PMID:17189198	PMID:21630459

Genomics

Comparative Map Data

Psmg2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	18	63,478,620 - 63,493,193 (+)	NCBI		GRCr8
mRatBN7.2	18	61,208,669 - 61,227,671 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	18	61,208,678 - 61,259,816 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	18	63,279,183 - 63,293,754 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	18	63,977,935 - 63,992,504 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	18	61,827,771 - 61,842,343 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	18	63,394,991 - 63,420,491 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	18	63,394,900 - 63,409,600 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	18	62,579,990 - 62,594,563 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	18	64,185,650 - 64,200,223 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	18	64,258,830 - 64,273,424 (+)	NCBI
Celera	18	59,314,858 - 59,329,453 (+)	NCBI		Celera
Cytogenetic Map	18	q12.1	NCBI

PSMG2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	18	12,658,738 - 12,725,740 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	18	12,658,043 - 12,728,945 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	18	12,658,737 - 12,725,739 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	18	12,693,064 - 12,715,739 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	18	12,693,063 - 12,715,737	NCBI
Celera	18	12,585,866 - 12,608,549 (+)	NCBI		Celera
Cytogenetic Map	18	p11.21	NCBI
HuRef	18	12,612,275 - 12,679,491 (+)	NCBI		HuRef
CHM1_1	18	12,658,110 - 12,725,109 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	18	12,821,722 - 12,888,739 (+)	NCBI		T2T-CHM13v2.0

Psmg2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	18	67,774,657 - 67,787,251 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	18	67,774,669 - 67,787,232 (+)	Ensembl		GRCm39 Ensembl
GRCm38	18	67,641,587 - 67,654,181 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	18	67,641,599 - 67,654,162 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	18	67,801,253 - 67,813,816 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	18	67,766,968 - 67,779,531 (+)	NCBI		MGSCv36	mm8
Celera	18	68,924,607 - 68,936,890 (+)	NCBI		Celera
Cytogenetic Map	18	E1	NCBI
cM Map	18	40.05	NCBI

Psmg2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955402	857,432 - 869,983 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955402	857,228 - 870,940 (-)	NCBI	ChiLan1.0	ChiLan1.0

PSMG2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	17	25,318,118 - 25,340,845 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	18	11,010,712 - 11,033,402 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	18	1,597,981 - 1,620,721 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	18	16,713,534 - 16,735,521 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	18	16,713,534 - 16,735,531 (-)	Ensembl	panpan1.1		panPan2

PSMG2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	7	78,092,877 - 78,112,831 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	7	78,092,876 - 78,112,702 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	7	77,494,973 - 77,514,440 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	7	78,153,405 - 78,172,880 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	7	78,153,509 - 78,172,751 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	7	77,849,808 - 77,869,048 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	7	77,897,849 - 77,917,285 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	7	78,184,113 - 78,203,586 (+)	NCBI		UU_Cfam_GSD_1.0

Psmg2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404944	3,099,720 - 3,116,515 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936626	2,329,678 - 2,344,897 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936626	2,328,646 - 2,344,831 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PSMG2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	96,878,139 - 96,893,474 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	96,879,009 - 96,893,551 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	90,304,114 - 90,318,719 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

PSMG2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	18	71,186,831 - 71,244,071 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	18	71,222,100 - 71,244,587 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666050	46,214,137 - 46,280,763 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Psmg2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624770	19,788,057 - 19,802,422 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624770	19,787,876 - 19,802,623 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Psmg2
82 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	50
Count of miRNA genes:	43
Interacting mature miRNAs:	47
Transcripts:	ENSRNOT00000024126
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1331733	Bp233	Blood pressure QTL 233	3.97196		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	24796977	79788953	Rat
1331741	Bp232	Blood pressure QTL 232	3.59112		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	18	21372893	83213037	Rat
1298072	Cia26	Collagen induced arthritis QTL 26	3.6		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	18	54709769	83828827	Rat
1300125	Rf26	Renal function QTL 26	3.2		urine potassium amount (VT:0010539)	urine potassium excretion rate (CMO:0000761)	18	52539863	65844950	Rat
631834	Sach3	Saccharin preference QTL 3	3.9	0.01	consumption behavior trait (VT:0002069)	calculated saccharin drink intake volume (CMO:0001600)	18	58805687	63636873	Rat
6893683	Bw110	Body weight QTL 110	2.7	0.002	body mass (VT:0001259)	body weight (CMO:0000012)	18	43345022	83828827	Rat
1331727	Bp237	Blood pressure QTL 237	3.053		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	31359408	61698465	Rat
9589041	Epfw12	Epididymal fat weight QTL 12	17.08	0.001	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	18	46640675	83828827	Rat
8694432	Bw165	Body weight QTL 165	3.81	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	18	46640675	83828827	Rat
70185	BpQTLcluster15	Blood pressure QTL cluster 15	4.61		arterial blood pressure trait (VT:2000000)	absolute change in systolic blood pressure (CMO:0000607)	18	59712417	76477814	Rat
9589816	Gluco68	Glucose level QTL 68	7.25	0.001	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	18	29792965	74792965	Rat
1331770	Bp234	Blood pressure QTL 234	3.807		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	59796478	71893566	Rat
2300177	Bmd65	Bone mineral density QTL 65	19.7	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	18	28964853	73964853	Rat
2301969	Bp324	Blood pressure QTL 324	4.05		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	18	59712417	76477814	Rat
1578667	Bss21	Bone structure and strength QTL 21	3.5		femur morphology trait (VT:0000559)	femoral neck cortical cross-sectional area (CMO:0001702)	18	11791518	83218561	Rat
2303120	Mamtr8	Mammary tumor resistance QTL 8		0.001	mammary gland integrity trait (VT:0010552)	mammary tumor growth rate (CMO:0000344)	18	31359408	83218561	Rat
12880368	Bw187	Body weight QTL 187		0.045	body mass (VT:0001259)	body weight (CMO:0000012)	18	52539763	76104388	Rat
724542	Kidm2	Kidney mass QTL 2	2.6		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	18	59172115	83828827	Rat
61367	Iddm4	Insulin dependent diabetes mellitus QTL 4	2.33	0.0074	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	18	38192455	83192455	Rat
2293658	Bmd23	Bone mineral density QTL 23	7.3	0.0001	femur mineral mass (VT:0010011)	total volumetric bone mineral density (CMO:0001728)	18	51464733	63636873	Rat
1359020	Ppulsi2	Prepulse inhibition QTL 2	2.71		prepulse inhibition trait (VT:0003088)	acoustic startle response measurement (CMO:0001519)	18	52292875	73997283	Rat
2312600	Bp341	Blood pressure QTL 341		0.05	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	18	59330409	70263868	Rat
9590318	Scort22	Serum corticosterone level QTL 22	7.64	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	18	29792965	74792965	Rat
1331752	Bw27	Body weight QTL 27	2.963		body mass (VT:0001259)	body weight (CMO:0000012)	18	52292875	65845095	Rat
1578661	Bss20	Bone structure and strength QTL 20	3.7		femur morphology trait (VT:0000559)	femoral neck cross-sectional area (CMO:0001697)	18	11791518	83218561	Rat
1331754	Bp230	Blood pressure QTL 230	4.61609		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	29792965	74792965	Rat
12904069	Cm123	Cardiac mass QTL 123		0.001	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	18	52539763	76104388	Rat
12904070	Cm124	Cardiac mass QTL 124		0.01	heart right ventricle mass (VT:0007033)	heart right ventricle weight to body weight ratio (CMO:0000914)	18	52539763	76104388	Rat
2303584	Gluco55	Glucose level QTL 55	2		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	18	48520044	83828827	Rat
12904071	Am18	Aortic mass QTL 18		0.001	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	18	52539763	76104388	Rat
12904067	Cm122	Cardiac mass QTL 122		0.001	heart mass (VT:0007028)	heart wet weight to body weight ratio (CMO:0002408)	18	52539763	76104388	Rat
61384	Bp48	Blood pressure QTL 48	19.4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	18	60622311	77209844	Rat
2301417	Bp319	Blood pressure QTL 319		0.002	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	52539763	76104388	Rat
12904073	Kidm71	Kidney mass QTL 71		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	18	52539763	76104388	Rat
6903353	Bp353	Blood pressure QTL 353	2.8		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	18	59796478	83828827	Rat
738008	Hcar14	Hepatocarcinoma resistance QTL 14	4.3		liver integrity trait (VT:0010547)	liver nonremodeling tumorous lesion number (CMO:0001462)	18	51464733	83218561	Rat
6903356	Bp354	Blood pressure QTL 354	4.6		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	59796478	83828827	Rat
631518	Bw11	Body weight QTL 11	2.8		body mass (VT:0001259)	body weight (CMO:0000012)	18	35870723	80870723	Rat
8694366	Abfw8	Abdominal fat weight QTL 8	6.38	0.001	visceral adipose mass (VT:0010063)	abdominal fat pad weight to body weight ratio (CMO:0000095)	18	46640675	83828827	Rat
631509	Sald2	Serum aldosterone level QTL 2	2.9		blood aldosterone amount (VT:0005346)	serum aldosterone level (CMO:0000487)	18	52539763	69140759	Rat
2300157	Bmd66	Bone mineral density QTL 66	13.1	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	18	28964853	73964853	Rat
738005	Anxrr11	Anxiety related response QTL 11	3.4		exploratory behavior trait (VT:0010471)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	18	30039813	75039813	Rat
631274	Sprol1	Serum protein level QTL 1	5.3		blood total protein amount (VT:0005567)	serum total protein level (CMO:0000661)	18	31393320	77209694	Rat
1358193	Emca2	Estrogen-induced mammary cancer QTL 2	1.6		mammary gland integrity trait (VT:0010552)	post-insult time to mammary tumor formation (CMO:0000345)	18	18007599	63571040	Rat
2293704	Bss35	Bone structure and strength QTL 35	4.59	0.0002	femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	18	28964853	73964853	Rat
2325839	Bp348	Blood pressure QTL 348		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	25570985	70570985	Rat
1600373	Mamtr6	Mammary tumor resistance QTL 6			mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	18	19278901	83218561	Rat
2293708	Bss46	Bone structure and strength QTL 46	8.8	0.0001	lumbar vertebra morphology trait (VT:0010494)	lumbar vertebra cortical cross-sectional area (CMO:0001690)	18	11791518	63636873	Rat
8694378	Bw157	Body weight QTL 157	3.59	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	18	29792965	74792965	Rat
1600375	Mcs22	Mammary carcinoma susceptibility QTL 22	3.3		mammary gland integrity trait (VT:0010552)	mammary tumor growth rate (CMO:0000344)	18	52539763	63933058	Rat
2303571	Bw92	Body weight QTL 92	3		body mass (VT:0001259)	body weight (CMO:0000012)	18	48520044	83828827	Rat
1598826	Anxrr20	Anxiety related response QTL 20	3.04		body movement coordination trait (VT:0005424)	number of rearing movements in an experimental apparatus (CMO:0001752)	18	41432971	83828827	Rat
631675	Iddm15	Insulin dependent diabetes mellitus QTL 15			urine glucose amount (VT:0001758)	percentage of study population developing diabetes mellitus during a period of time (CMO:0001114)	18	60622311	77209844	Rat
61429	Cia17	Collagen induced arthritis QTL 17	4.6		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	18	31359408	70263868	Rat
7411719	Strs5	Sensitivity to stroke QTL 5	9.4		cerebrum integrity trait (VT:0010549)	percentage of study population developing cerebrovascular lesions during a period of time (CMO:0000932)	18	49999958	65845095	Rat

Markers in Region

BF400698

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	18	61,215,105 - 61,215,250 (+)	MAPPER	mRatBN7.2
Rnor_6.0	18	63,401,392 - 63,401,536	NCBI	Rnor6.0
Rnor_5.0	18	62,586,354 - 62,586,498	UniSTS	Rnor5.0
RGSC_v3.4	18	64,192,014 - 64,192,158	UniSTS	RGSC3.4
Celera	18	59,321,244 - 59,321,388	UniSTS
RH 3.4 Map	18	622.3	UniSTS
Cytogenetic Map	18	q12.1	UniSTS

BE107548

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	18	61,208,477 - 61,208,671 (+)	MAPPER	mRatBN7.2
Rnor_6.0	18	63,394,764 - 63,394,957	NCBI	Rnor6.0
Rnor_5.0	18	62,579,726 - 62,579,919	UniSTS	Rnor5.0
RGSC_v3.4	18	64,185,386 - 64,185,579	UniSTS	RGSC3.4
Celera	18	59,314,594 - 59,314,787	UniSTS
RH 3.4 Map	18	620.1	UniSTS
Cytogenetic Map	18	q12.1	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	113	91	90	59	25	59	6	218	97	93	45	60	31

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001106138	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008772117	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063277192	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BM387084	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CB798672	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473971	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	DV720222	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ212569	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ230678	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000018	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000024126 ⟹ ENSRNOP00000024126

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	18	61,208,678 - 61,223,291 (+)	Ensembl
Rnor_6.0 Ensembl	18	63,394,900 - 63,409,600 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000094532 ⟹ ENSRNOP00000079587

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	18	61,208,758 - 61,223,314 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000097990 ⟹ ENSRNOP00000088243

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	18	61,208,678 - 61,259,816 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000098439 ⟹ ENSRNOP00000091115

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	18	61,208,678 - 61,221,821 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000118836 ⟹ ENSRNOP00000080920

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	18	61,208,678 - 61,222,540 (+)	Ensembl

RefSeq Acc Id:

NM_001106138 ⟹ NP_001099608

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	18	63,478,620 - 63,493,193 (+)	NCBI
mRatBN7.2	18	61,208,742 - 61,223,315 (+)	NCBI
Rnor_6.0	18	63,395,028 - 63,409,601 (+)	NCBI
Rnor_5.0	18	62,579,990 - 62,594,563 (+)	NCBI
RGSC_v3.4	18	64,185,650 - 64,200,223 (+)	RGD
Celera	18	59,314,858 - 59,329,453 (+)	RGD

Sequence:

show sequence

TTCTATCCTAAGGATAGGTATCCTAGCTGTCCCGGACAGCGCTCCAGCTTCTCTTACGCCCACT
GCAGTCATGTTCGTTCCCTGCGGGGAGTCGGTCCCCGACCTAAAGAACTTCACACTCCTGATGC
CAGCAGTATCCGTTGGGAATGTTGGCCAGCTTGCAATAGATTTGATTATTTCTACACTGAACAT
GTGTAAGATTGGGTATTTCTATACTGATTGCCTGGTGCCAATGGTTGGGAACAATCCATATGCA
ACTGAAGAAGAAGACTGGAATGAGCTCAGTATAAATGCTGAAGTGTATTCCTTACCGTCAAAGA
AGCTAGTGGTGCTTCAGCTCAGGTCCATCTTCATTAAGTATAAATCCAAGTCATTCTGTGAAAA
ACTGCTGGCCTGGGCAGAAAGTAGCTGCTGTGCCAGGATCATCGTTCTCTCCAGCAGCCACTCA
TATCACCGTACTGATGTACAACTCCGCAGTACTCCCTTTCGGTATCTTCTTACACCTTGTTTGC
AAAAGAGTGTTCAAAATAAAATAAAGAGCCTAAACTGGCTAGAAATGGAAAAGAGTCGGTGCAT
CCCCGAGATGAGTGATTCTGAGTTCTGCATTCGCATTCCCGGAGGTGGAATCACAAAAACACTC
TATGAGGAAAGCTGTTGTAAAGAAATCCAAATGGCAGTTCTGCTGAAATTTGTTTCAGAAGGGG
ACAATATCCCAGATGCAGTCAGCCTTGTGGAGTATCTTAATGAATGGCTTCAGATAATCAAACC
ATGTAGTGACGGCCCCGTGGCCTCTGTCTTGCCATGGAAGATCCCCAGCTCTTGGCGGCTGCTC
TTTGGCAGTGGACTTCCTCCCGCACTGTTCTGATCTGTTTTCAGCCTTCTCCCTCGCCCCGCAG
ACATCACAAAACCAGCTGTTGGGTGTGTGCTGTGCAGAATTTTGTGCTGCCCCGGGGTGTGTTA
GAAGTGCTATAGTAAAACCTCGAAGAAAAGAGGTTGTAAAGGTTATTATGCTTGTTATATACAA
TAAATGTAAATTCTGTACAATAAATTATATTTACTAAGCAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_063277192 ⟹ XP_063133262

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	18	63,482,238 - 63,493,193 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001099608	(Get FASTA)	NCBI Sequence Viewer
	XP_063133262	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDM14739	(Get FASTA)	NCBI Sequence Viewer
	EDM14740	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000024126.4
	ENSRNOP00000079587.1
	ENSRNOP00000080920.1
	ENSRNOP00000088243.1
	ENSRNOP00000091115.1

RefSeq Acc Id:

NP_001099608 ⟸ NM_001106138

- UniProtKB:

D3ZAQ4 (UniProtKB/TrEMBL), A0A8I6G3H9 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MFVPCGESVPDLKNFTLLMPAVSVGNVGQLAIDLIISTLNMCKIGYFYTDCLVPMVGNNPYATE
EEDWNELSINAEVYSLPSKKLVVLQLRSIFIKYKSKSFCEKLLAWAESSCCARIIVLSSSHSYH
RTDVQLRSTPFRYLLTPCLQKSVQNKIKSLNWLEMEKSRCIPEMSDSEFCIRIPGGGITKTLYE
ESCCKEIQMAVLLKFVSEGDNIPDAVSLVEYLNEWLQIIKPCSDGPVASVLPWKIPSSWRLLFG
SGLPPALF

hide sequence

Ensembl Acc Id:

ENSRNOP00000024126 ⟸ ENSRNOT00000024126

Ensembl Acc Id:

ENSRNOP00000079587 ⟸ ENSRNOT00000094532

Ensembl Acc Id:

ENSRNOP00000091115 ⟸ ENSRNOT00000098439

Ensembl Acc Id:

ENSRNOP00000080920 ⟸ ENSRNOT00000118836

Ensembl Acc Id:

ENSRNOP00000088243 ⟸ ENSRNOT00000097990

RefSeq Acc Id:	XP_063133262 ⟸ XM_063277192
- Peptide Label:	isoform X1

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D3ZAQ4-F1-model_v2	AlphaFold	D3ZAQ4	1-264	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13700847

Promoter ID:

EPDNEW_R11371

Type:

initiation region

Name:

Psmg2_1

Description:

proteasome assembly chaperone 2

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	18	63,395,025 - 63,395,085	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1304867	AgrOrtholog
BioCyc Gene	G2FUF-7133	BioCyc
Ensembl Genes	ENSRNOG00000017729	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000024126.8	UniProtKB/TrEMBL
	ENSRNOT00000094532.1	UniProtKB/TrEMBL
	ENSRNOT00000097990.1	UniProtKB/TrEMBL
	ENSRNOT00000098439.1	UniProtKB/TrEMBL
	ENSRNOT00000118836.1	UniProtKB/TrEMBL
Gene3D-CATH	3.40.50.10900	UniProtKB/TrEMBL
InterPro	Proteasome_assmbl_chaperone_2	UniProtKB/TrEMBL
	Proteasome_assmbl_chp_2_euk	UniProtKB/TrEMBL
	PSMG2_sf	UniProtKB/TrEMBL
KEGG Report	rno:291539	UniProtKB/TrEMBL
NCBI Gene	291539	ENTREZGENE
PANTHER	PROTEASOME ASSEMBLY CHAPERONE 2	UniProtKB/TrEMBL
	PTHR12970	UniProtKB/TrEMBL
Pfam	HCCA3	UniProtKB/TrEMBL
PhenoGen	Psmg2	PhenoGen
PIRSF	UCP010044	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000017729	RatGTEx
Superfamily-SCOP	Cgl1923-like	UniProtKB/TrEMBL
UniProt	A0A8I5ZQU8_RAT	UniProtKB/TrEMBL
	A0A8I6ABG3_RAT	UniProtKB/TrEMBL
	A0A8I6G3H9	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6GG02_RAT	UniProtKB/TrEMBL
	D3ZAQ4	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-04-14	Psmg2	proteasome assembly chaperone 2	Psmg2	proteasome (prosome, macropain) assembly chaperone 2	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-05-02	Psmg2	proteasome (prosome, macropain) assembly chaperone 2	Tnfsf5ip1	tumor necrosis factor superfamily, member 5-induced protein 1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	Tnfsf5ip1	tumor necrosis factor superfamily, member 5-induced protein 1	Tnfsf5ip1_predicted	tumor necrosis factor superfamily, member 5-induced protein 1 (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-12	Tnfsf5ip1_predicted	tumor necrosis factor superfamily, member 5-induced protein 1 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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