Sprol1 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL Registration

QTL: Sprol1 (Serum protein level QTL 1) Rattus norvegicus

Symbol: Sprol1
Name: Serum protein level QTL 1
RGD ID: 631274
Previously known as: Serum phospholipid level QTL 3; Spl3; Sp1; Serum protein QTL 1
Trait: blood total protein amount   (VT:0005567)    
Measurement Type: serum total protein level   (CMO:0000661)    
LOD Score: 5.3
P Value: Not Available
Variance: Not Available
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81831,644,508 - 79,484,311RGD_MAPPER_PIPELINE
mRatBN7.21831,393,320 - 77,209,694RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01832,704,022 - 80,696,226RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01832,348,480 - 79,748,238RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.41832,459,145 - 80,370,367RGDRGSC3.4
RGSC_v3.11832,494,411 - 80,443,810RGD
Cross Type: intercross
Strains Crossed: BB/OK SHR/Mol 
JBrowse: View Region in Genome Browser (JBrowse)
Model




  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Sprol1Ratdisease of metabolism  IAGP 61055 RGD 

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Sprol1Ratincreased circulating total protein level  QTM 61055 RGD 

Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Sprol1Ratserum total protein level  IDA 61055 RGD 

Experimental Condition
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Sprol1Ratcontrol condition  IDA 61055 RGD 

Measurement Method
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Sprol1Ratblood protein analysis  IDA 61055 RGD 

Rat Strain
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Sprol1RatBB/OK  IEA 61055 RGD 
Sprol1RatSHR/Mol  IEA 61055 RGD 

Vertebrate Trait
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Sprol1Ratblood total protein amount  IDA 61055 RGD 


#
Reference Title
Reference Citation
1. Sensitivity to cerebral ischaemic insult in a rat model of stroke is determined by a single genetic locus. Jeffs B, etal., Nat Genet 1997 Aug;16(4):364-7
2. Novel quantitative trait loci for blood pressure and related traits on rat chromosomes 1, 10, and 18. Kovacs P, etal., Biochem Biophys Res Commun 1997 Jun 18;235(2):343-8


1 to 20 of 552 rows
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
2741Nr3c1nuclear receptor subfamily 3, group C, member 1183127168131393320Rat
1310759Pabpc2poly(A) binding protein, cytoplasmic 2183165421831656486Rat
11361905LOC108348849glyceraldehyde-3-phosphate dehydrogenase pseudogene183189817631899193Rat
1359165Yipf5Yip1 domain family, member 5183212381432136947Rat
1559856Kctd16potassium channel tetramerization domain containing 16183216623632473067Rat
41244098Ube2c-ps3ubiquitin-conjugating enzyme E2C, pseudogene 3183232131632321725Rat
40943372Trnap-agg42transfer RNA proline (anticodon AGG) 42183263524732635327Rat
41231671LOC120098435U6 spliceosomal RNA183274616632746268Rat
1590896Kpna1-ps4karyopherin subunit alpha 1, pseudogene 4183276966932776779Rat
41196987LOC120093049small nucleolar RNA SNORA19183304590833046048Rat
1585817Rpl36-ps14ribosomal protein L36, pseudogene183328138633281699Rat
2323363Rplp0-ps6ribosomal protein lateral stalk subunit P0, pseudogene 6183366415833665636Rat
41130071Ppp2r2d-ps1protein phosphatase 2, regulatory subunit B, delta, pseudogene 1183376815333771743Rat
2323168Selenok-ps5selenoprotein K, pseudogene 5183377230033772969Rat
6502918Atp5mg-ps5ATP synthase membrane subunit g, pseudogene 5183382700033827309Rat
41168943LOC120098429U6 spliceosomal RNA183383705933837165Rat
1588514Tkt-ps1transketolase, pseudogene 1183384251033844384Rat
11502477LOC10834885040S ribosomal protein S28 pseudogene183385617433856387Rat
1584707Prelid2PRELI domain containing 2183386993433961320Rat
9179805LOC103694262cyclin-dependent kinase 1 pseudogene183390562033906471Rat

1 to 20 of 552 rows
1 to 20 of 757 rows
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Expected Size
Chr
Start
Stop
Species
Match
5506407UniSTS:479186606183165523731655843Ratregion
1579097D18Chm43214183198368231983896Ratregion
60744D18Rat143212183204049732040709Ratregion
5061478BE11184990183212412532124215Ratregion
5073164RH137277199183213765632137855Ratregion
5065282BE121378191183222251032222701Ratregion
5067168AU047919221183226817132268392Ratregion
5090173AU049594170183242905832429228Ratregion
45559D18Got27157183243172132431878Ratregion
5049770RH133672180183246158532461765Ratregion
5065608BF406016176183247520432475380Ratregion
5047540RH132386181183247679032476971Ratregion
5068028AU047393277183257873032579007Ratregion
43118D18Rat141203183273218732732390Ratregion
1579057D18Chm44227183299174432991975Ratregion
1579057D18Chm44227183299174432992360Ratregion
1579057D18Chm44227183299193432991975Ratregion
1632643D18Mco8276183317612933176405Ratregion
1628145D18Ulb1239183317613033176369Ratregion
5504020px-28f9332183362996033630292Ratregion
1 to 20 of 757 rows

Flank 1: (D18Mit9)
Rat AssemblyChrPosition (strand)Source
GRCr81879,484,311 - 79,484,461 (+)Marker Load Pipeline
mRatBN7.21877,209,694 - 77,209,844 (+)MAPPER
Rnor_6.01880,696,226 - 80,696,375NCBI
Rnor_5.01879,748,238 - 79,748,387UniSTS
RGSC_v3.41880,370,367 - 80,370,517RGD
RGSC_v3.41880,370,368 - 80,370,517UniSTS
RGSC_v3.11880,443,810 - 80,444,102RGD
Celera1875,835,913 - 75,836,062UniSTS
RH 3.4 Map18814.4UniSTS
RH 3.4 Map18814.4RGD
RH 2.0 Map1853.0RGD
SHRSP x BN Map1849.0499RGD
FHH x ACI Map1860.7699RGD
Cytogenetic Map7q36UniSTS
Peak: (Gnal)
Rat AssemblyChrPosition (strand)Source
GRCr81862,892,257 - 63,032,510 (+)NCBI
mRatBN7.21860,622,311 - 60,762,599 (+)NCBI
mRatBN7.2 Ensembl1860,622,311 - 60,762,599 (+)Ensembl
UTH_Rnor_SHR_Utx1862,697,583 - 62,835,273 (+)NCBI
UTH_Rnor_SHRSP_BbbUtx_1.01863,396,310 - 63,534,014 (+)NCBI
UTH_Rnor_WKY_Bbb_1.01861,243,031 - 61,383,188 (+)NCBI
Rnor_6.01862,805,406 - 62,946,133 (+)NCBI
Rnor_6.0 Ensembl1862,805,410 - 62,944,630 (+)Ensembl
Rnor_5.01861,991,738 - 62,131,420 (+)NCBI
RGSC_v3.41863,595,606 - 63,735,803 (+)NCBI
RGSC_v3.11863,668,806 - 63,809,004 (+)NCBI
Celera1858,730,137 - 58,870,361 (+)NCBI
Cytogenetic Map18q12.1NCBI
Flank 2: (Nr3c1)
Rat AssemblyChrPosition (strand)Source
GRCr81831,522,783 - 31,644,508 (-)NCBI
mRatBN7.21831,271,681 - 31,393,320 (-)NCBI
mRatBN7.2 Ensembl1831,271,681 - 31,393,375 (-)Ensembl
UTH_Rnor_SHR_Utx1831,375,854 - 31,463,901 (-)NCBI
UTH_Rnor_SHRSP_BbbUtx_1.01832,142,851 - 32,230,932 (-)NCBI
UTH_Rnor_WKY_Bbb_1.01831,471,103 - 31,559,156 (-)NCBI
Rnor_6.01831,728,373 - 32,704,022 (-)NCBI
Rnor_6.0 Ensembl1831,728,373 - 31,749,647 (-)Ensembl
Rnor_5.01832,347,227 - 32,348,480 (-)NCBI
Rnor_5.01831,408,742 - 31,442,725 (-)NCBI
RGSC_v3.41832,371,496 - 32,459,145 (-)NCBI
RGSC_v3.11832,406,765 - 32,494,411 (-)NCBI
Celera1830,905,394 - 30,993,522 (-)NCBI
RH 3.4 Map18442.9RGD
Cytogenetic Map18p11NCBI


1 to 10 of 92 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1331733Bp233Blood pressure QTL 2333.97196arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)182479697779788953Rat
1358358Sradr6Stress Responsive Adrenal Weight QTL 62.49adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)181194429959330563Rat
1331730Scl27Serum cholesterol level QTL 273.826blood HDL cholesterol amount (VT:0000184)serum high density lipoprotein cholesterol level (CMO:0000361)185229287559796643Rat
1331741Bp232Blood pressure QTL 2323.59112arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)182137289383213037Rat
1331742Bp228Blood pressure QTL 2283.88752arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183135940859796643Rat
1298072Cia26Collagen induced arthritis QTL 263.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)185470976983828827Rat
1331736Bp227Blood pressure QTL 2272.791arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)184671876359796643Rat
1300125Rf26Renal function QTL 263.2urine potassium amount (VT:0010539)urine potassium excretion rate (CMO:0000761)185253986365844950Rat
631834Sach3Saccharin preference QTL 33.90.01consumption behavior trait (VT:0002069)calculated saccharin drink intake volume (CMO:0001600)185880568763636873Rat
12904668Bw188Body weight QTL 1880.03body mass (VT:0001259)body weight (CMO:0000012)182654808246969551Rat

1 to 10 of 92 rows


Database
Acc Id
Source(s)
NCBI Gene Spl3


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-06-25 Sprol1  Serum protein level QTL 1  Spl3  Serum phospholipid level QTL 3  Symbol updated 68687 APPROVED
2013-06-25 Sprol1  Serum protein level QTL 1  Spl3  Serum phospholipid level QTL 3  Name updated 68913 APPROVED
2013-06-24 Spl3  Serum phospholipid level QTL 3  Spl3  Serum phospholipid level QTL 3  Name updated 68913 APPROVED
2004-09-08 Spl3  Serum phospholipid level QTL 3  Sp1  Serum protein QTL 1  Symbol and Name updated 1299863 APPROVED

Note Type Note Reference
qtl_cross_type intercross  
qtl_general associates with the increased level of total serum protein 61055