(-)-epigallocatechin 3-gallate multiple interactions ISO RGD:736846 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in increased expression of LOX mRNA CTD PMID:22079256 1-naphthyl isothiocyanate increases expression EXP 6480464 1-Naphthylisothiocyanate results in increased expression of LOX mRNA CTD PMID:25380136 17alpha-ethynylestradiol affects expression EXP 6480464 Ethinyl Estradiol affects the expression of LOX mRNA CTD PMID:16079270 17alpha-ethynylestradiol multiple interactions ISO RGD:732343 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in decreased expression of LOX mRNA CTD PMID:17942748 17beta-estradiol affects expression ISO RGD:736846 6480464 Estradiol affects the expression of LOX mRNA CTD PMID:14699072 17beta-estradiol increases expression ISO RGD:732343 6480464 Estradiol results in increased expression of LOX mRNA CTD PMID:19484750 17beta-estradiol multiple interactions ISO RGD:736846 6480464 [Estradiol binds to ESR2 protein] which results in increased expression of LOX mRNA, [Estradiol co-treated with TGFB1 protein] results in increased expression of LOX mRNA CTD PMID:20404318 , PMID:30165855 17beta-estradiol decreases expression ISO RGD:736846 6480464 Estradiol results in decreased expression of LOX mRNA CTD PMID:20106945 , PMID:21632981 17beta-hydroxy-5alpha-androstan-3-one increases expression ISO RGD:736846 6480464 Dihydrotestosterone results in increased expression of LOX mRNA CTD PMID:29581250 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:732343 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in decreased expression of LOX mRNA CTD PMID:17942748 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:732343 6480464 Tetrachlorodibenzodioxin results in increased expression of LOX mRNA CTD PMID:16922920 , PMID:27562557 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:732343 6480464 Tetrachlorodibenzodioxin affects the expression of LOX mRNA CTD PMID:26377647 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of LOX mRNA CTD PMID:16054898 more ... 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:736846 6480464 Tetrachlorodibenzodioxin results in decreased expression of LOX mRNA CTD PMID:20106945 , PMID:21632981 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of LOX mRNA CTD PMID:22298810 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:732343 6480464 Tetrachlorodibenzodioxin results in decreased expression of LOX mRNA CTD PMID:19770486 2,3,7,8-Tetrachlorodibenzofuran decreases expression EXP 6480464 2 more ... CTD PMID:21724226 2,4,6-trinitrobenzenesulfonic acid multiple interactions ISO RGD:732343 6480464 Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of LOX mRNA] CTD PMID:18200517 2,4,6-trinitrobenzenesulfonic acid increases expression ISO RGD:732343 6480464 Trinitrobenzenesulfonic Acid results in increased expression of LOX mRNA CTD PMID:17982090 , PMID:18200517 2-butoxyethanol decreases expression ISO RGD:732343 6480464 n-butoxyethanol results in decreased expression of LOX mRNA CTD PMID:19812364 3,3',4,4',5-pentachlorobiphenyl decreases expression EXP 6480464 3 more ... CTD PMID:23196670 3,3',5,5'-tetrabromobisphenol A decreases expression ISO RGD:732343 6480464 tetrabromobisphenol A results in decreased expression of LOX mRNA CTD PMID:25172293 3-methylcholanthrene decreases expression ISO RGD:732343 6480464 Methylcholanthrene results in decreased expression of LOX mRNA CTD PMID:20713471 3H-1,2-dithiole-3-thione increases expression EXP 6480464 1, 2-dithiol-3-thione results in increased expression of LOX mRNA CTD PMID:19162173 4,4'-diaminodiphenylmethane increases expression EXP 6480464 4, 4'-diaminodiphenylmethane results in increased expression of LOX mRNA CTD PMID:25380136 4,4'-sulfonyldiphenol increases expression ISO RGD:732343 6480464 bis(4-hydroxyphenyl)sulfone results in increased expression of LOX mRNA CTD PMID:30951980 4,4'-sulfonyldiphenol multiple interactions ISO RGD:732343 6480464 [bis(4-hydroxyphenyl)sulfone co-treated with Tretinoin] results in decreased expression of LOX mRNA CTD PMID:30951980 4-hydroxyphenyl retinamide increases expression ISO RGD:732343 6480464 Fenretinide results in increased expression of LOX mRNA CTD PMID:28973697 5-aza-2'-deoxycytidine increases expression ISO RGD:736846 6480464 Decitabine results in increased expression of LOX mRNA CTD PMID:17908484 5-aza-2'-deoxycytidine affects expression ISO RGD:736846 6480464 Decitabine affects the expression of LOX mRNA CTD PMID:17194187 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole affects expression EXP 6480464 Omeprazole affects the expression of LOX mRNA CTD PMID:19483382 6-propyl-2-thiouracil affects expression EXP 6480464 Propylthiouracil affects the expression of LOX mRNA CTD PMID:19483382 , PMID:24780913 acrylamide decreases expression EXP 6480464 Acrylamide results in decreased expression of LOX mRNA CTD PMID:28959563 aflatoxin B1 affects expression ISO RGD:736846 6480464 Aflatoxin B1 affects the expression of LOX protein CTD PMID:20106945 aflatoxin B1 decreases methylation ISO RGD:736846 6480464 Aflatoxin B1 results in decreased methylation of LOX gene CTD PMID:27153756 aflatoxin B1 decreases expression ISO RGD:736846 6480464 Aflatoxin B1 results in decreased expression of LOX mRNA CTD PMID:21632981 , PMID:21641981 alendronic acid affects expression EXP 6480464 Alendronate affects the expression of LOX mRNA CTD PMID:16079270 all-trans-retinoic acid decreases expression ISO RGD:736846 6480464 Tretinoin results in decreased expression of LOX mRNA CTD PMID:23724009 all-trans-retinoic acid multiple interactions ISO RGD:732343 6480464 [bis(4-hydroxyphenyl)sulfone co-treated with Tretinoin] results in decreased expression of LOX mRNA more ... CTD PMID:30951980 amiodarone affects expression EXP 6480464 Amiodarone affects the expression of LOX mRNA CTD PMID:18355885 , PMID:19483382 amitriptyline affects expression EXP 6480464 Amitriptyline affects the expression of LOX mRNA CTD PMID:18355885 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of LOX mRNA CTD PMID:16483693 ampicillin increases expression ISO RGD:736846 6480464 Ampicillin results in increased expression of LOX mRNA CTD PMID:21632981 antirheumatic drug increases expression ISO RGD:736846 6480464 Antirheumatic Agents results in increased expression of LOX mRNA CTD PMID:24449571 arsenite(3-) increases expression ISO RGD:736846 6480464 arsenite results in increased expression of LOX mRNA CTD PMID:23974009 benzbromarone affects expression EXP 6480464 Benzbromarone affects the expression of LOX mRNA CTD PMID:19483382 benzo[a]pyrene decreases expression ISO RGD:732343 6480464 Benzo(a)pyrene results in decreased expression of LOX mRNA CTD PMID:19770486 benzo[a]pyrene affects expression ISO RGD:732343 6480464 Benzo(a)pyrene affects the expression of LOX mRNA CTD PMID:22342234 benzo[a]pyrene decreases expression ISO RGD:736846 6480464 Benzo(a)pyrene results in decreased expression of LOX mRNA CTD PMID:20106945 , PMID:21632981 benzo[a]pyrene increases expression ISO RGD:732343 6480464 Benzo(a)pyrene results in increased expression of LOX mRNA CTD PMID:21569818 beta-aminopropionitrile decreases activity EXP 6480464 Aminopropionitrile results in decreased activity of LOX protein CTD PMID:19524603 beta-aminopropionitrile multiple interactions ISO RGD:736846 6480464 Aminopropionitrile inhibits the reaction [cupric chloride results in increased activity of LOX protein] CTD PMID:25044713 beta-aminopropionitrile decreases activity ISO RGD:732343 6480464 Aminopropionitrile results in decreased activity of LOX protein CTD PMID:22367676 beta-aminopropionitrile decreases activity ISO RGD:736846 6480464 Aminopropionitrile results in decreased activity of LOX protein CTD PMID:16023247 beta-naphthoflavone multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of LOX mRNA CTD PMID:18164116 bexarotene decreases expression EXP 6480464 bexarotene results in decreased expression of LOX mRNA CTD PMID:16648578 bis(2-ethylhexyl) phthalate decreases expression ISO RGD:736846 6480464 Diethylhexyl Phthalate results in decreased expression of LOX mRNA CTD PMID:28412506 bis(2-ethylhexyl) phthalate increases expression ISO RGD:736846 6480464 Diethylhexyl Phthalate results in increased expression of LOX mRNA CTD PMID:31163220 bisphenol A decreases expression ISO RGD:736846 6480464 bisphenol A results in decreased expression of LOX mRNA CTD PMID:22576693 bisphenol A increases expression ISO RGD:732343 6480464 bisphenol A results in increased expression of LOX mRNA CTD PMID:30951980 bisphenol A multiple interactions ISO RGD:732343 6480464 [bisphenol A co-treated with Tretinoin] results in decreased expression of LOX mRNA CTD PMID:30951980 bisphenol A affects expression ISO RGD:736846 6480464 bisphenol A affects the expression of LOX mRNA CTD PMID:30903817 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of LOX mRNA CTD PMID:25181051 bisphenol A multiple interactions EXP 6480464 [bisphenol A co-treated with Testosterone] results in increased expression of LOX mRNA CTD PMID:26496021 bisphenol F multiple interactions ISO RGD:732343 6480464 [bisphenol F co-treated with Tretinoin] results in decreased expression of LOX mRNA CTD PMID:30951980 bisphenol F increases expression ISO RGD:732343 6480464 bisphenol F results in increased expression of LOX mRNA CTD PMID:30951980 brucine decreases expression ISO RGD:732343 6480464 brucine results in decreased expression of LOX mRNA, brucine results in decreased expression of LOX protein CTD PMID:23933019 brucine decreases expression ISO RGD:736846 6480464 brucine results in decreased expression of LOX mRNA CTD PMID:23933019 cadmium atom affects methylation EXP 6480464 Cadmium affects the methylation of LOX promoter CTD PMID:25741534 cadmium atom decreases expression EXP 6480464 Cadmium results in decreased expression of LOX CTD PMID:19879314 cadmium atom affects expression EXP 6480464 Cadmium affects the expression of LOX CTD PMID:25741534 cadmium dichloride decreases activity EXP 6480464 Cadmium Chloride results in decreased activity of LOX CTD PMID:19879314 cadmium dichloride decreases expression EXP 6480464 Cadmium Chloride results in decreased expression of LOX mRNA CTD PMID:25993096 cadmium dichloride multiple interactions EXP 6480464 Cadmium Chloride inhibits the reaction [cobaltous chloride promotes the reaction [HIF1A protein binds to LOX promoter]] CTD PMID:23161664 cadmium dichloride multiple interactions ISO RGD:732343 6480464 [Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of LOX mRNA CTD PMID:19840844 calcitriol increases expression ISO RGD:736846 6480464 Calcitriol results in increased expression of LOX mRNA CTD PMID:16002434 carbon nanotube increases expression ISO RGD:732343 6480464 Nanotubes, Carbon analog results in increased expression of LOX mRNA, Nanotubes, Carbon results in increased expression of LOX mRNA CTD PMID:25554681 carvedilol decreases expression EXP 6480464 carvedilol results in decreased expression of LOX mRNA CTD PMID:21216836 chloroprene increases expression ISO RGD:732343 6480464 Chloroprene results in increased expression of LOX mRNA CTD PMID:23125180 chloroprene increases expression EXP 6480464 Chloroprene results in increased expression of LOX mRNA CTD PMID:23125180 ciglitazone multiple interactions ISO RGD:736846 6480464 [ciglitazone binds to PPARG protein alternative form] which results in increased expression of LOX mRNA CTD PMID:16197558 cisplatin decreases expression EXP 6480464 Cisplatin results in decreased expression of LOX mRNA CTD PMID:22023808 cisplatin multiple interactions ISO RGD:736846 6480464 [Cisplatin co-treated with Paclitaxel] results in decreased expression of LOX mRNA CTD PMID:20705681 clofibrate affects expression EXP 6480464 Clofibrate affects the expression of LOX mRNA CTD PMID:19483382 clofibrate increases expression ISO RGD:732343 6480464 Clofibrate results in increased expression of LOX mRNA CTD PMID:17585979 clomipramine affects expression EXP 6480464 Clomipramine affects the expression of LOX mRNA CTD PMID:18355885 clothianidin increases expression ISO RGD:736846 6480464 clothianidin results in increased expression of LOX mRNA CTD PMID:29044138 cobalt dichloride increases expression ISO RGD:736846 6480464 cobaltous chloride results in increased expression of LOX mRNA, cobaltous chloride results in increased expression of LOX protein CTD PMID:24614111 cobalt dichloride increases expression EXP 6480464 cobaltous chloride results in increased expression of LOX mRNA CTD PMID:23161664 cobalt dichloride multiple interactions EXP 6480464 Cadmium Chloride inhibits the reaction [cobaltous chloride promotes the reaction [HIF1A protein binds to LOX promoter]] more ... CTD PMID:23161664 cocaine decreases expression EXP 6480464 Cocaine results in decreased expression of LOX mRNA CTD PMID:17898221 copper atom multiple interactions EXP 6480464 [Copper deficiency co-treated with tetrathiomolybdate] results in decreased expression of LOX mRNA, [Copper deficiency co-treated with tetrathiomolybdate] results in decreased expression of LOX protein CTD PMID:22276220 copper atom decreases expression EXP 6480464 Copper results in decreased expression of LOX mRNA CTD PMID:30556269 copper atom multiple interactions ISO RGD:732343 6480464 [ATP7A gene mutant form results in increased abundance of Copper] which results in increased expression of LOX mRNA CTD PMID:15467011 copper(0) multiple interactions EXP 6480464 [Copper deficiency co-treated with tetrathiomolybdate] results in decreased expression of LOX mRNA, [Copper deficiency co-treated with tetrathiomolybdate] results in decreased expression of LOX protein CTD PMID:22276220 copper(0) decreases expression EXP 6480464 Copper results in decreased expression of LOX mRNA CTD PMID:30556269 copper(0) multiple interactions ISO RGD:732343 6480464 [ATP7A gene mutant form results in increased abundance of Copper] which results in increased expression of LOX mRNA CTD PMID:15467011 copper(II) chloride increases activity ISO RGD:732343 6480464 cupric chloride results in increased activity of LOX protein CTD PMID:22367676 copper(II) chloride multiple interactions ISO RGD:736846 6480464 Aminopropionitrile inhibits the reaction [cupric chloride results in increased activity of LOX protein] CTD PMID:25044713 copper(II) chloride increases activity ISO RGD:736846 6480464 cupric chloride results in increased activity of LOX protein CTD PMID:25044713 copper(II) sulfate increases expression ISO RGD:736846 6480464 Copper Sulfate results in increased expression of LOX mRNA CTD PMID:20599845 copper(II) sulfate decreases expression ISO RGD:736846 6480464 Copper Sulfate results in decreased expression of LOX mRNA CTD PMID:19549813 , PMID:20599845 curcumin multiple interactions ISO RGD:732343 6480464 Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of LOX mRNA] CTD PMID:18200517 cyclosporin A decreases expression ISO RGD:736846 6480464 Cyclosporine results in decreased expression of LOX mRNA CTD PMID:20106945 more ... cytarabine decreases expression ISO RGD:736846 6480464 Cytarabine results in decreased expression of LOX mRNA CTD PMID:21198554 DDT decreases expression EXP 6480464 DDT results in decreased expression of LOX mRNA CTD PMID:30207508 decabromodiphenyl ether decreases expression EXP 6480464 decabromobiphenyl ether results in decreased expression of LOX mRNA CTD PMID:23640034 Deguelin multiple interactions ISO RGD:736846 6480464 deguelin inhibits the reaction [Oxygen deficiency results in increased expression of LOX mRNA] CTD PMID:22745725 desferrioxamine B multiple interactions ISO RGD:736846 6480464 [Deferoxamine results in decreased abundance of Iron] which results in increased expression of LOX mRNA CTD PMID:12393473 dexamethasone increases expression ISO RGD:732343 6480464 Dexamethasone results in increased expression of LOX mRNA CTD PMID:10926554 , PMID:22733784 dextran sulfate multiple interactions ISO RGD:732343 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of LOX mRNA CTD PMID:29950665 diallyl trisulfide multiple interactions ISO RGD:736846 6480464 diallyl trisulfide inhibits the reaction [Oxygen deficiency results in increased expression of LOX mRNA] CTD PMID:28574600 dibutyl phthalate increases expression EXP 6480464 Dibutyl Phthalate results in increased expression of LOX mRNA CTD PMID:21266533 dicrotophos increases expression ISO RGD:736846 6480464 dicrotophos results in increased expression of LOX mRNA CTD PMID:28302478 dioxygen multiple interactions ISO RGD:736846 6480464 (+)-JQ1 compound inhibits the reaction [Oxygen deficiency results in increased expression of LOX mRNA] more ... CTD PMID:22745725 more ... dioxygen multiple interactions ISO RGD:732343 6480464 [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of LOX mRNA CTD PMID:30529165 dioxygen increases expression ISO RGD:736846 6480464 Oxygen deficiency results in increased expression of LOX mRNA, Oxygen deficiency results in increased expression of LOX protein CTD PMID:18924134 more ... dioxygen increases activity ISO RGD:736846 6480464 Oxygen deficiency results in increased activity of LOX protein CTD PMID:25044713 dioxygen increases expression ISO RGD:732343 6480464 Oxygen deficiency results in increased expression of LOX mRNA, Oxygen deficiency results in increased expression of LOX protein CTD PMID:24614111 diuron decreases expression EXP 6480464 Diuron results in decreased expression of LOX mRNA CTD PMID:25152437 dorsomorphin multiple interactions ISO RGD:736846 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of LOX mRNA CTD PMID:27188386 doxorubicin affects response to substance ISO RGD:736846 6480464 LOX protein affects the susceptibility to Doxorubicin CTD PMID:16217747 doxorubicin increases expression ISO RGD:736846 6480464 Doxorubicin results in increased expression of LOX mRNA CTD PMID:29803840 doxorubicin decreases expression ISO RGD:736846 6480464 Doxorubicin results in decreased expression of LOX mRNA CTD PMID:22908232 doxorubicin multiple interactions ISO RGD:732343 6480464 [[MT1 protein co-treated with MT2 protein] affects the susceptibility to Doxorubicin] which affects the expression of LOX mRNA CTD PMID:21040762 doxorubicin increases expression ISO RGD:732343 6480464 Doxorubicin results in increased expression of LOX mRNA CTD PMID:21040762 doxorubicin affects expression ISO RGD:732343 6480464 Doxorubicin affects the expression of LOX mRNA CTD PMID:15033991 endosulfan decreases expression EXP 6480464 Endosulfan results in decreased expression of LOX mRNA CTD PMID:29391264 ethanol multiple interactions ISO RGD:732343 6480464 [Carbon Tetrachloride co-treated with Ethanol] results in increased expression of LOX mRNA CTD PMID:30517762 ethanol increases expression ISO RGD:736846 6480464 Ethanol results in increased expression of LOX mRNA CTD PMID:23378141 ethanol multiple interactions ISO RGD:736846 6480464 [Ethanol co-treated with Folic Acid] results in increased expression of LOX mRNA CTD PMID:23378141 flutamide increases expression EXP 6480464 Flutamide results in increased expression of LOX mRNA CTD PMID:21525395 folic acid multiple interactions ISO RGD:736846 6480464 [Ethanol co-treated with Folic Acid] results in increased expression of LOX mRNA CTD PMID:23378141 furan increases expression EXP 6480464 furan results in increased expression of LOX mRNA CTD PMID:27387713 glycidol increases expression EXP 6480464 glycidol results in increased expression of LOX mRNA CTD PMID:24395379 hemin multiple interactions ISO RGD:736846 6480464 [Hemin results in decreased abundance of Iron] which results in increased expression of LOX mRNA CTD PMID:12393473 hydrogen peroxide affects expression ISO RGD:736846 6480464 Hydrogen Peroxide affects the expression of LOX mRNA CTD PMID:23410634 imipramine affects expression EXP 6480464 Imipramine affects the expression of LOX mRNA CTD PMID:18355885 iron atom multiple interactions ISO RGD:736846 6480464 [Deferoxamine results in decreased abundance of Iron] which results in increased expression of LOX mRNA, [Hemin results in decreased abundance of Iron] which results in increased expression of LOX mRNA CTD PMID:12393473 iron(0) multiple interactions ISO RGD:736846 6480464 [Deferoxamine results in decreased abundance of Iron] which results in increased expression of LOX mRNA, [Hemin results in decreased abundance of Iron] which results in increased expression of LOX mRNA CTD PMID:12393473 isoprenaline increases expression ISO RGD:732343 6480464 Isoproterenol results in increased expression of LOX mRNA CTD PMID:20003209 ketoconazole affects expression EXP 6480464 Ketoconazole affects the expression of LOX mRNA CTD PMID:18355885 L-ethionine affects expression EXP 6480464 Ethionine affects the expression of LOX mRNA CTD PMID:19483382 lead(0) affects expression ISO RGD:736846 6480464 Lead affects the expression of LOX mRNA CTD PMID:28903495 lead(2+) affects expression ISO RGD:736846 6480464 Lead affects the expression of LOX mRNA CTD PMID:28903495 linoleic acid multiple interactions ISO RGD:732343 6480464 FADS2 protein inhibits the reaction [Linoleic Acid results in increased activity of LOX protein], TGFB1 protein promotes the reaction [Linoleic Acid results in increased activity of LOX protein] CTD PMID:26240151 linoleic acid increases activity ISO RGD:732343 6480464 Linoleic Acid results in increased activity of LOX protein CTD PMID:26240151 losartan decreases expression EXP 6480464 Losartan results in decreased expression of LOX mRNA CTD PMID:15100363 manganese(II) chloride decreases expression EXP 6480464 manganese chloride results in decreased expression of LOX mRNA CTD PMID:28801915 menadione affects expression ISO RGD:736846 6480464 Vitamin K 3 affects the expression of LOX mRNA CTD PMID:23410634 methapyrilene decreases expression EXP 6480464 Methapyrilene results in decreased expression of LOX mRNA CTD PMID:30467583 mifepristone decreases expression EXP 6480464 Mifepristone results in decreased expression of LOX mRNA CTD PMID:25972201 N-methyl-4-phenylpyridinium decreases expression EXP 6480464 1-Methyl-4-phenylpyridinium results in decreased expression of LOX mRNA CTD PMID:28801915 N-methyl-N'-nitro-N-nitrosoguanidine multiple interactions ISO RGD:732343 6480464 [Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of LOX mRNA more ... CTD PMID:19840844 N-nitrosodiethylamine multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of LOX mRNA CTD PMID:18164116 N-nitrosodiethylamine increases expression ISO RGD:736846 6480464 Diethylnitrosamine results in increased expression of LOX mRNA CTD PMID:21527772 N-nitrosomorpholine affects expression EXP 6480464 N-nitrosomorpholine affects the expression of LOX mRNA CTD PMID:19716841 naphthalene increases expression ISO RGD:732343 6480464 naphthalene results in increased expression of LOX mRNA CTD PMID:18978301 nefazodone decreases expression EXP 6480464 nefazodone results in decreased expression of LOX mRNA CTD PMID:24136188 nickel atom increases expression ISO RGD:732343 6480464 Nickel results in increased expression of LOX mRNA CTD PMID:12540486 nickel dichloride increases expression ISO RGD:736846 6480464 nickel chloride results in increased expression of LOX mRNA CTD PMID:17312168 , PMID:21455298 nickel sulfate increases expression ISO RGD:736846 6480464 nickel sulfate results in increased expression of LOX mRNA CTD PMID:17382205 nickel sulfate decreases expression ISO RGD:736846 6480464 nickel sulfate results in decreased expression of LOX mRNA CTD PMID:22714537 nitrofen decreases expression EXP 6480464 nitrofen results in decreased expression of LOX mRNA, nitrofen results in decreased expression of LOX protein CTD PMID:25111273 okadaic acid multiple interactions ISO RGD:732343 6480464 [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of LOX mRNA CTD PMID:19840844 oleic acid increases activity ISO RGD:732343 6480464 Oleic Acid results in increased activity of LOX protein CTD PMID:26240151 omeprazole affects expression EXP 6480464 Omeprazole affects the expression of LOX mRNA CTD PMID:19483382 oxaliplatin increases expression EXP 6480464 oxaliplatin results in increased expression of LOX mRNA CTD PMID:25729387 oxaliplatin multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in increased expression of LOX mRNA CTD PMID:25729387 ozone increases expression ISO RGD:732343 6480464 Ozone results in increased expression of LOX mRNA CTD PMID:17095637 paclitaxel multiple interactions ISO RGD:736846 6480464 [Cisplatin co-treated with Paclitaxel] results in decreased expression of LOX mRNA CTD PMID:20705681 paracetamol affects expression ISO RGD:732343 6480464 Acetaminophen affects the expression of LOX mRNA CTD PMID:17562736 paracetamol decreases expression EXP 6480464 Acetaminophen results in decreased expression of LOX mRNA CTD PMID:17202762 , PMID:30723492 pentane-2,3-dione increases expression EXP 6480464 2, 3-pentanedione results in increased expression of LOX mRNA CTD PMID:25710175 perfluorooctane-1-sulfonic acid decreases expression EXP 6480464 perfluorooctane sulfonic acid results in decreased expression of LOX mRNA CTD PMID:19162173 perfluorooctanoic acid decreases expression EXP 6480464 perfluorooctanoic acid results in decreased expression of LOX mRNA CTD PMID:16221955 , PMID:19162173 phenylmercury acetate increases expression ISO RGD:736846 6480464 Phenylmercuric Acetate results in increased expression of LOX mRNA CTD PMID:26272509 phenylmercury acetate multiple interactions ISO RGD:736846 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of LOX mRNA CTD PMID:27188386 phorbol 13-acetate 12-myristate multiple interactions ISO RGD:732343 6480464 [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of LOX mRNA CTD PMID:19840844 pirinixic acid affects expression EXP 6480464 pirinixic acid affects the expression of LOX mRNA CTD PMID:19483382 potassium chromate increases expression ISO RGD:736846 6480464 potassium chromate(VI) results in increased expression of LOX mRNA CTD PMID:22079256 potassium chromate multiple interactions ISO RGD:736846 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in increased expression of LOX mRNA CTD PMID:22079256 potassium dichromate decreases expression ISO RGD:732343 6480464 Potassium Dichromate results in decreased expression of LOX mRNA CTD PMID:23608068 progesterone increases expression ISO RGD:732343 6480464 Progesterone results in increased expression of LOX mRNA CTD PMID:22238285 quercetin decreases expression ISO RGD:736846 6480464 Quercetin results in decreased expression of LOX mRNA CTD PMID:21632981 quinolin-8-ol decreases expression ISO RGD:736846 6480464 Oxyquinoline results in decreased expression of LOX mRNA CTD PMID:21632981 raloxifene affects expression EXP 6480464 Raloxifene Hydrochloride affects the expression of LOX mRNA CTD PMID:16079270 rotenone decreases expression EXP 6480464 Rotenone results in decreased expression of LOX mRNA CTD PMID:28374803 SB 431542 multiple interactions ISO RGD:736846 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of LOX mRNA CTD PMID:27188386 semicarbazide decreases activity EXP 6480464 carbamylhydrazine results in decreased activity of LOX protein CTD PMID:19524603 sevoflurane affects expression EXP 6480464 sevoflurane affects the expression of LOX mRNA CTD PMID:15967596 silicon dioxide decreases expression ISO RGD:736846 6480464 Silicon Dioxide analog results in decreased expression of LOX mRNA CTD PMID:25895662 silver atom decreases expression ISO RGD:732343 6480464 Silver results in decreased expression of LOX mRNA CTD PMID:27131904 silver(0) decreases expression ISO RGD:732343 6480464 Silver results in decreased expression of LOX mRNA CTD PMID:27131904 simvastatin decreases expression EXP 6480464 Simvastatin results in decreased expression of LOX mRNA CTD PMID:16414398 sodium arsenate increases expression ISO RGD:732343 6480464 sodium arsenate results in increased expression of LOX mRNA CTD PMID:21795629 sodium dichromate decreases expression EXP 6480464 sodium bichromate results in decreased expression of LOX mRNA CTD PMID:25993096 sulforaphane decreases expression ISO RGD:732343 6480464 sulforafan results in decreased expression of LOX mRNA CTD PMID:30529165 sulindac decreases expression ISO RGD:736846 6480464 Sulindac analog results in decreased expression of LOX mRNA CTD PMID:18924134 tauroursodeoxycholic acid decreases expression EXP 6480464 tauroursodeoxycholic acid results in decreased expression of LOX mRNA CTD PMID:15885361 tert-butyl hydroperoxide affects expression ISO RGD:736846 6480464 tert-Butylhydroperoxide affects the expression of LOX mRNA CTD PMID:23410634 testosterone multiple interactions EXP 6480464 [bisphenol A co-treated with Testosterone] results in increased expression of LOX mRNA CTD PMID:26496021 tetrachloromethane affects expression ISO RGD:732343 6480464 Carbon Tetrachloride affects the expression of LOX mRNA CTD PMID:17484886 tetrachloromethane multiple interactions ISO RGD:732343 6480464 [Carbon Tetrachloride co-treated with 1-trifluoromethoxyphenyl-3-(1-propionylpiperidine-4-yl)urea] results in increased expression of LOX mRNA, [Carbon Tetrachloride co-treated with Ethanol] results in increased expression of LOX mRNA CTD PMID:25827057 , PMID:30517762 tetrachloromethane increases expression ISO RGD:732343 6480464 Carbon Tetrachloride results in increased expression of LOX mRNA CTD PMID:15056808 , PMID:25827057 tetrathiomolybdate(2-) multiple interactions EXP 6480464 [Copper deficiency co-treated with tetrathiomolybdate] results in decreased expression of LOX mRNA, [Copper deficiency co-treated with tetrathiomolybdate] results in decreased expression of LOX protein CTD PMID:22276220 thioacetamide affects expression EXP 6480464 Thioacetamide affects the expression of LOX mRNA CTD PMID:19483382 thioacetamide increases expression EXP 6480464 Thioacetamide results in increased expression of LOX mRNA CTD PMID:23411599 titanium dioxide increases expression ISO RGD:732343 6480464 titanium dioxide results in increased expression of LOX mRNA CTD PMID:27760801 titanium dioxide multiple interactions ISO RGD:732343 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of LOX mRNA CTD PMID:29950665 titanium dioxide decreases expression ISO RGD:732343 6480464 titanium dioxide results in decreased expression of LOX mRNA CTD PMID:23409001 toluene increases expression EXP 6480464 Toluene results in increased expression of LOX mRNA CTD PMID:22967744 topotecan multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in increased expression of LOX mRNA CTD PMID:25729387 topotecan increases expression EXP 6480464 Topotecan results in increased expression of LOX mRNA CTD PMID:25729387 Trapidil multiple interactions EXP 6480464 Trapidil affects the reaction [PTH protein affects the expression of LOX mRNA] CTD PMID:18635661 tributylstannane increases expression EXP 6480464 tributyltin results in increased expression of LOX mRNA CTD PMID:21683754 trimellitic anhydride increases expression ISO RGD:732343 6480464 trimellitic anhydride results in increased expression of LOX mRNA CTD PMID:19042947 tris(2-butoxyethyl) phosphate affects expression ISO RGD:736846 6480464 tris(2-butoxyethyl) phosphate affects the expression of LOX mRNA CTD PMID:29024780 troglitazone increases expression ISO RGD:732343 6480464 troglitazone results in increased expression of LOX mRNA CTD PMID:28973697 urethane decreases expression ISO RGD:736846 6480464 Urethane results in decreased expression of LOX mRNA CTD PMID:28818685 ursodeoxycholic acid decreases expression EXP 6480464 Ursodeoxycholic Acid results in decreased expression of LOX mRNA CTD PMID:15885361 valproic acid increases expression ISO RGD:736846 6480464 Valproic Acid results in increased expression of LOX mRNA CTD PMID:19101580 , PMID:28001369 valproic acid increases expression ISO RGD:732343 6480464 Valproic Acid results in increased expression of LOX mRNA CTD PMID:24896083 valproic acid decreases expression ISO RGD:736846 6480464 Valproic Acid results in decreased expression of LOX mRNA CTD PMID:23179753 , PMID:29154799 vinclozolin decreases expression EXP 6480464 vinclozolin results in decreased expression of LOX mRNA CTD PMID:23034163
Biological Process aorta development ISO RGD:732343 1624291 (MGI:MGI:5644076, PMID:25807483) RGD MGI:MGI:5644076 , PMID:25807483 ascending aorta development IEA UniProtKB:P28301 , ensembl:ENSMUSP000000254091600115 GO_REF:0000107 Ensembl GO_REF:0000107 ascending aorta development ISO RGD:732343 1624291 MGI:MGI:2657016 (MGI:MGI:5912605 , PMID:28550176) RGD MGI:MGI:5912605 , PMID:28550176 blood vessel development ISO RGD:732343 1624291 MGI:MGI:3610732 (MGI:MGI:3609311 , PMID:12417550) RGD MGI:MGI:3609311 , PMID:12417550 blood vessel morphogenesis ISO RGD:732343 1624291 (MGI:MGI:5816638, PMID:27432961) RGD MGI:MGI:5816638 , PMID:27432961 blood vessel morphogenesis ISS UniProtKB:P28301 1600115 GO_REF:0000024 UniProt GO_REF:0000024 bone mineralization IEA UniProtKB:P28301 , ensembl:ENSMUSP000000254091600115 GO_REF:0000107 Ensembl GO_REF:0000107 bone mineralization ISO RGD:732343 1624291 MGI:MGI:3610732 (MGI:MGI:5603515 , PMID:19458888) RGD MGI:MGI:5603515 , PMID:19458888 cell chemotaxis ISO RGD:732343 1624291 MGI:MGI:3610732 (MGI:MGI:3813418 , PMID:18586678) RGD MGI:MGI:3813418 , PMID:18586678 cell chemotaxis IMP 14390060 PMID:18586678 MGI cellular response to chemokine IEA UniProtKB:P28301 , ensembl:ENSMUSP000000254091600115 GO_REF:0000107 Ensembl GO_REF:0000107 cellular response to chemokine ISO RGD:732343 1624291 MGI:MGI:3610732 (MGI:MGI:3813418 , PMID:18586678) RGD MGI:MGI:3813418 , PMID:18586678 cellular response to organic substance ISO RGD:732343 1624291 (MGI:MGI:5918750, PMID:28800626) RGD MGI:MGI:5918750 , PMID:28800626 collagen fibril organization IDA 1600668 RGD collagen fibril organization ISO RGD:732343 1624291 MGI:MGI:3610732 (MGI:MGI:3604822 more ... RGD MGI:MGI:3604822 more ... collagen fibril organization IMP 1600669 RGD connective tissue development IEA UniProtKB:P28301 , ensembl:ENSMUSP000000254091600115 GO_REF:0000107 Ensembl GO_REF:0000107 connective tissue development ISO RGD:732343 1624291 MGI:MGI:98725 (MGI:MGI:5634219 , PMID:25715398) RGD MGI:MGI:5634219 , PMID:25715398 descending aorta development IEA UniProtKB:P28301 , ensembl:ENSMUSP000000254091600115 GO_REF:0000107 Ensembl GO_REF:0000107 descending aorta development ISO RGD:732343 1624291 MGI:MGI:2657016 (MGI:MGI:5912605 , PMID:28550176) RGD MGI:MGI:5912605 , PMID:28550176 DNA biosynthetic process IEA UniProtKB:P28301 , ensembl:ENSMUSP000000254091600115 GO_REF:0000107 Ensembl GO_REF:0000107 DNA biosynthetic process ISO RGD:732343 1624291 MGI:MGI:3610732 (MGI:MGI:5603515 , PMID:19458888) RGD MGI:MGI:5603515 , PMID:19458888 elastic fiber assembly IMP 1600669 RGD elastic fiber assembly ISO RGD:732343 1624291 MGI:MGI:3610732 (MGI:MGI:3604822 more ... RGD MGI:MGI:3604822 more ... heart development ISO RGD:732343 1624291 (MGI:MGI:5644076, PMID:25807483) RGD MGI:MGI:5644076 , PMID:25807483 heart development IEA UniProtKB:P28301 , ensembl:ENSMUSP000000254091600115 GO_REF:0000107 Ensembl GO_REF:0000107 lung development ISO RGD:732343 1624291 MGI:MGI:3610732 (MGI:MGI:3604822 , PMID:16192629) RGD MGI:MGI:3604822 , PMID:16192629 lung development IEA UniProtKB:P28301 , ensembl:ENSMUSP000000254091600115 GO_REF:0000107 Ensembl GO_REF:0000107 muscle cell cellular homeostasis IEA UniProtKB:P28301 , ensembl:ENSMUSP000000254091600115 GO_REF:0000107 Ensembl GO_REF:0000107 muscle cell cellular homeostasis ISO RGD:732343 1624291 MGI:MGI:98725 (MGI:MGI:5634219 , PMID:25715398) RGD MGI:MGI:5634219 , PMID:25715398 muscle fiber development IEA UniProtKB:P28301 , ensembl:ENSMUSP000000254091600115 GO_REF:0000107 Ensembl GO_REF:0000107 muscle fiber development ISO RGD:732343 1624291 MGI:MGI:3610732 (MGI:MGI:5634219 , PMID:25715398) RGD MGI:MGI:5634219 , PMID:25715398 osteoblast differentiation IEA UniProtKB:P28301 , ensembl:ENSMUSP000000254091600115 GO_REF:0000107 Ensembl GO_REF:0000107 osteoblast differentiation ISO RGD:732343 1624291 MGI:MGI:3610732 (MGI:MGI:5603515 , PMID:19458888) RGD MGI:MGI:5603515 , PMID:19458888 peptidyl-lysine oxidation IBA MGI:MGI:1337004 more ... 13792537 PMID:21873635 GO_Central peptidyl-lysine oxidation ISO RGD:736846 1624291 (PMID:31152061) RGD PMID:31152061 peptidyl-lysine oxidation ISS UniProtKB:P28300 1600115 GO_REF:0000024 UniProt GO_REF:0000024 platelet-derived growth factor receptor-beta signaling pathway ISO RGD:732343 1624291 MGI:MGI:3610732 (MGI:MGI:3813418 , PMID:18586678) RGD MGI:MGI:3813418 , PMID:18586678 platelet-derived growth factor receptor-beta signaling pathway IMP 14390060 PMID:18586678 MGI protein kinase B signaling IEA UniProtKB:P28301 , ensembl:ENSMUSP000000254091600115 GO_REF:0000107 Ensembl GO_REF:0000107 protein kinase B signaling ISO RGD:732343 1624291 MGI:MGI:2657016 (MGI:MGI:6112149 , PMID:28538980) RGD MGI:MGI:6112149 , PMID:28538980 protein oxidation IMP 14390060 PMID:18586678 MGI regulation of apoptotic process IEA UniProtKB:P28301 , ensembl:ENSMUSP000000254091600115 GO_REF:0000107 Ensembl GO_REF:0000107 regulation of apoptotic process ISO RGD:732343 1624291 MGI:MGI:2657016 (MGI:MGI:6112149 , PMID:28538980) RGD MGI:MGI:6112149 , PMID:28538980 regulation of bone development IEA UniProtKB:P28301 , ensembl:ENSMUSP000000254091600115 GO_REF:0000107 Ensembl GO_REF:0000107 regulation of bone development ISO RGD:732343 1624291 MGI:MGI:2657016 (MGI:MGI:5293278 , PMID:21665949) RGD MGI:MGI:5293278 , PMID:21665949 regulation of gene expression IEA UniProtKB:P28301 , ensembl:ENSMUSP000000254091600115 GO_REF:0000107 Ensembl GO_REF:0000107 regulation of gene expression ISO RGD:732343 1624291 MGI:MGI:2657016 (MGI:MGI:6101304 , PMID:28285904) RGD MGI:MGI:6101304 , PMID:28285904 regulation of megakaryocyte differentiation IEA UniProtKB:P28301 , ensembl:ENSMUSP000000254091600115 GO_REF:0000107 Ensembl GO_REF:0000107 regulation of megakaryocyte differentiation ISO RGD:732343 1624291 MGI:MGI:2657016 (MGI:MGI:5293278 , PMID:21665949) RGD MGI:MGI:5293278 , PMID:21665949 regulation of platelet-derived growth factor receptor-beta signaling pathway IEA UniProtKB:P28301 , ensembl:ENSMUSP000000254091600115 GO_REF:0000107 Ensembl GO_REF:0000107 regulation of platelet-derived growth factor receptor-beta signaling pathway ISO RGD:732343 1624291 MGI:MGI:2657016 (MGI:MGI:5293278 , PMID:21665949) RGD MGI:MGI:5293278 , PMID:21665949 regulation of protein phosphorylation IEA UniProtKB:P28301 , ensembl:ENSMUSP000000254091600115 GO_REF:0000107 Ensembl GO_REF:0000107 regulation of protein phosphorylation ISO RGD:732343 1624291 (MGI:MGI:3828240, PMID:18835815) RGD MGI:MGI:3828240 , PMID:18835815 regulation of receptor binding ISO RGD:732343 1624291 MGI:MGI:3610732 (MGI:MGI:3813418 , PMID:18586678) RGD MGI:MGI:3813418 , PMID:18586678 regulation of receptor binding IMP 14390060 PMID:18586678 MGI regulation of striated muscle tissue development IEA UniProtKB:P28301 , ensembl:ENSMUSP000000254091600115 GO_REF:0000107 Ensembl GO_REF:0000107 regulation of striated muscle tissue development ISO RGD:732343 1624291 MGI:MGI:3610732 (MGI:MGI:5634219 , PMID:25715398) RGD MGI:MGI:5634219 , PMID:25715398 regulation of transforming growth factor beta receptor signaling pathway IEA UniProtKB:P28301 , ensembl:ENSMUSP000000254091600115 GO_REF:0000107 Ensembl GO_REF:0000107 regulation of transforming growth factor beta receptor signaling pathway ISO RGD:732343 1624291 MGI:MGI:3610732 (MGI:MGI:5634219 , PMID:25715398) RGD MGI:MGI:5634219 , PMID:25715398 response to drug IEP 1581902 RGD response to hormone IDA 729248 RGD response to steroid hormone IDA 729248 RGD wound healing IMP 1600668 RGD wound healing IEP 1581902 RGD Cellular Component cell IEA GO:0046716 1600115 GO_REF:0000108 GOC GO_REF:0000108 collagen trimer ISO RGD:732343 1624291 (MGI:MGI:65985, PMID:7901452) RGD MGI:MGI:65985 , PMID:7901452 collagen trimer IEA UniProtKB:P28301 , ensembl:ENSMUSP000000254091600115 GO_REF:0000107 Ensembl GO_REF:0000107 extracellular matrix IDA 8553592 PMID:16251195 MGI extracellular matrix ISO RGD:732343 1624291 (MGI:MGI:1101283 more ... RGD MGI:MGI:1101283 more ... extracellular region ISO RGD:732343 1624291 (MGI:MGI:5816638, PMID:27432961) RGD MGI:MGI:5816638 , PMID:27432961 extracellular space IBA MGI:MGI:1337004 more ... 13792537 PMID:21873635 GO_Central extracellular space ISO RGD:736846 1624291 (PMID:31152061) RGD PMID:31152061 extracellular space ISS UniProtKB:P28300 1600115 GO_REF:0000024 UniProt GO_REF:0000024 extracellular space IBA MGI:MGI:1337004 more ... 13792537 PMID:21873635 GO_Central nucleus IDA 1581906 RGD Molecular Function collagen binding ISS UniProtKB:P28300 1600115 GO_REF:0000024 UniProt GO_REF:0000024 collagen binding ISO RGD:736846 1624291 (PMID:31152061) RGD PMID:31152061 copper ion binding IMP 1600669 RGD protein binding ISO RGD:732343 1624291 UniProtKB:P04049 more ... RGD MGI:MGI:3616956 more ... protein binding ISO RGD:736846 1624291 UniProtKB:O95967 more ... RGD PMID:19570982 more ... protein-lysine 6-oxidase activity IDA 1600668 RGD protein-lysine 6-oxidase activity ISO RGD:736846 1624291 (PMID:31152061) RGD PMID:31152061 protein-lysine 6-oxidase activity IBA MGI:MGI:1337004 more ... 13792537 PMID:21873635 GO_Central protein-lysine 6-oxidase activity ISO RGD:732343 1624291 (MGI:MGI:3029035 more ... RGD MGI:MGI:3029035 more ... protein-lysine 6-oxidase activity IMP 1600669 RGD
Gene-Chemical Interaction Annotations
