Lox (lysyl oxidase) - Rat Genome Database

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Gene: Lox (lysyl oxidase) Mus musculus
Analyze
Symbol: Lox
Name: lysyl oxidase
RGD ID: 732343
MGI Page MGI
Description: Exhibits protein-lysine 6-oxidase activity. Involved in several processes, including circulatory system development; extracellular matrix organization; and regulation of signal transduction. Localizes to collagen trimer; extracellular matrix; and extracellular region. Is expressed in several structures, including alimentary system; cardiovascular system; genitourinary system; nervous system; and sensory organ. Used to study Menkes disease and Williams-Beuren syndrome. Human ortholog(s) of this gene implicated in Ehlers-Danlos syndrome; Menkes disease; hypertension; and thoracic aortic aneurysm. Orthologous to human LOX (lysyl oxidase).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AI893619; protein-lysine 6-oxidase; ras excision protein; ras recision; ras recision gene (rrg); rrg; TSC-16; TSC-160
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391852,649,132 - 52,662,939 (-)NCBIGRCm39mm39
GRCm39 Ensembl1852,649,139 - 52,662,939 (-)Ensembl
GRCm381852,516,060 - 52,529,867 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1852,516,067 - 52,529,867 (-)EnsemblGRCm38mm10GRCm38
MGSCv371852,676,892 - 52,689,362 (-)NCBIGRCm37mm9NCBIm37
MGSCv361852,641,436 - 52,655,072 (-)NCBImm8
Celera1853,829,941 - 53,842,352 (-)NCBICelera
Cytogenetic Map18D1NCBI
cM Map1828.22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
1-naphthyl isothiocyanate  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP,ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
2,4,6-trinitrobenzenesulfonic acid  (EXP)
2-butoxyethanol  (EXP)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3,3',5,5'-tetrabromobisphenol A  (EXP)
3-methylcholanthrene  (EXP)
3H-1,2-dithiole-3-thione  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (EXP)
4-hydroxyphenyl retinamide  (EXP)
5-aza-2'-deoxycytidine  (ISO)
5-chloro-7-iodoquinolin-8-ol  (ISO)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (ISO)
6-propyl-2-thiouracil  (ISO)
acetamide  (ISO)
acrylamide  (ISO)
aflatoxin B1  (ISO)
alendronic acid  (ISO)
all-trans-retinoic acid  (EXP,ISO)
amiodarone  (ISO)
amitriptyline  (ISO)
ammonium chloride  (ISO)
ampicillin  (ISO)
antirheumatic drug  (ISO)
aristolochic acid  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
benzbromarone  (ISO)
benzo[a]pyrene  (EXP,ISO)
beta-aminopropionitrile  (EXP,ISO)
beta-naphthoflavone  (ISO)
bexarotene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP)
bromobenzene  (ISO)
brucine  (EXP,ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
calcitriol  (ISO)
carbon nanotube  (EXP)
carvedilol  (ISO)
chlorohydrocarbon  (ISO)
chloroprene  (EXP,ISO)
ciglitazone  (ISO)
cisplatin  (ISO)
clofibrate  (EXP,ISO)
clomipramine  (ISO)
clothianidin  (ISO)
cobalt dichloride  (ISO)
cocaine  (ISO)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
copper(II) chloride  (EXP,ISO)
copper(II) sulfate  (ISO)
crocidolite asbestos  (EXP)
curcumin  (EXP)
cyclosporin A  (ISO)
cytarabine  (ISO)
DDT  (ISO)
decabromodiphenyl ether  (ISO)
Deguelin  (ISO)
desferrioxamine B  (ISO)
dexamethasone  (EXP)
dextran sulfate  (EXP)
diallyl trisulfide  (ISO)
dibutyl phthalate  (ISO)
dicrotophos  (ISO)
dioxygen  (EXP,ISO)
diuron  (ISO)
dorsomorphin  (ISO)
doxorubicin  (EXP,ISO)
endosulfan  (ISO)
ethanol  (EXP,ISO)
fenvalerate  (ISO)
flutamide  (ISO)
folic acid  (ISO)
furan  (ISO)
glycidol  (ISO)
hemin  (ISO)
hydrogen peroxide  (ISO)
hydrogen sulfide  (EXP)
imipramine  (ISO)
iron atom  (ISO)
iron(0)  (ISO)
isoprenaline  (EXP)
ketoconazole  (ISO)
L-ethionine  (ISO)
lead(0)  (ISO)
lead(2+)  (ISO)
linoleic acid  (EXP)
losartan  (ISO)
manganese(II) chloride  (ISO)
menadione  (ISO)
metformin  (ISO)
methapyrilene  (ISO)
methylmercury chloride  (ISO)
mifepristone  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-methyl-N'-nitro-N-nitrosoguanidine  (EXP)
N-nitrosodiethylamine  (ISO)
N-nitrosomorpholine  (ISO)
naphthalene  (EXP)
nefazodone  (ISO)
nickel atom  (EXP)
nickel dichloride  (ISO)
nickel sulfate  (ISO)
nitrofen  (ISO)
okadaic acid  (EXP)
oleic acid  (EXP)
omeprazole  (ISO)
oxaliplatin  (ISO)
ozone  (EXP)
paclitaxel  (ISO)
paracetamol  (EXP,ISO)
pentane-2,3-dione  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
phenylmercury acetate  (ISO)
phorbol 13-acetate 12-myristate  (EXP)
pirinixic acid  (ISO)
potassium chromate  (ISO)
potassium dichromate  (EXP)
progesterone  (EXP)
quercetin  (ISO)
quinolin-8-ol  (ISO)
raloxifene  (ISO)
rotenone  (ISO)
SB 431542  (ISO)
semicarbazide  (ISO)
sevoflurane  (ISO)
silicon dioxide  (ISO)
silver atom  (EXP)
silver(0)  (EXP)
simvastatin  (ISO)
sodium arsenate  (EXP,ISO)
sodium arsenite  (EXP)
sodium dichromate  (ISO)
sulforaphane  (EXP)
sulindac  (ISO)
sunitinib  (ISO)
tauroursodeoxycholic acid  (ISO)
tert-butyl hydroperoxide  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP)
tetrathiomolybdate(2-)  (ISO)
thioacetamide  (ISO)
titanium dioxide  (EXP)
toluene  (ISO)
topotecan  (ISO)
Trapidil  (ISO)
tributylstannane  (ISO)
trimellitic anhydride  (EXP)
triphenyl phosphate  (ISO)
tris(2-butoxyethyl) phosphate  (ISO)
troglitazone  (EXP)
urethane  (ISO)
ursodeoxycholic acid  (ISO)
valproic acid  (EXP,ISO)
vinclozolin  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal aorta elastic tissue morphology  (IAGP)
abnormal aorta smooth muscle morphology  (IAGP)
abnormal aorta wall morphology  (IAGP)
abnormal blood flow velocity  (IAGP)
abnormal blood vessel elastic tissue morphology  (IAGP)
abnormal blood vessel morphology  (IEA)
abnormal bronchiole epithelium morphology  (IAGP)
abnormal craniofacial morphology  (IEA)
abnormal cutaneous collagen fibril morphology  (IAGP)
abnormal cutaneous elastic fiber morphology  (IAGP)
abnormal descending thoracic aorta morphology  (IAGP)
abnormal diaphragm central tendon morphology  (IAGP)
abnormal diaphragm development  (IAGP)
abnormal diaphragm morphology  (IAGP)
abnormal enzyme/coenzyme activity  (IAGP)
abnormal kidney morphology  (IEA)
abnormal placenta morphology  (IEA)
abnormal pulmonary acinus morphology  (IAGP)
abnormal pulmonary artery morphology  (IAGP)
abnormal pulmonary elastic fiber morphology  (IAGP)
abnormal skin morphology  (IEA)
abnormal spleen morphology  (IEA)
abnormal suckling behavior  (IAGP)
aorta stenosis  (IAGP)
aortic aneurysm  (IAGP)
atelectasis  (IAGP)
cyanosis  (IAGP)
decreased aorta elastin content  (IAGP)
decreased aorta wall thickness  (IAGP)
decreased lung weight  (IAGP)
decreased skin tensile strength  (IAGP)
decreased tumor latency  (IAGP)
diaphragmatic hernia  (IAGP)
dilated respiratory conducting tubes  (IAGP)
edema  (IEA)
emphysema  (IAGP)
enlarged spleen  (IEA)
heart left ventricle hypertrophy  (IEA)
heart right ventricle hypertrophy  (IEA)
hemoperitoneum  (IAGP)
hemorrhage  (IAGP)
hemothorax  (IAGP)
hypoactivity  (IAGP)
impaired branching involved in respiratory bronchiole morphogenesis  (IAGP)
impaired branching involved in terminal bronchiole morphogenesis  (IAGP)
increased incidence of tumors by chemical induction  (IAGP)
increased lymphocyte cell number  (IAGP)
increased sensitivity to induced morbidity/mortality  (IAGP)
perinatal lethality, complete penetrance  (IAGP)
preweaning lethality, complete penetrance  (IEA)
pulmonary artery stenosis  (IEA)
pulmonary hypoplasia  (IAGP)
semilunar valve regurgitation  (IAGP)
small kidney  (IEA)
supravalvar aortic stenosis  (IEA)
References

Additional References at PubMed
PMID:14140   PMID:20889   PMID:1358813   PMID:1594588   PMID:1678898   PMID:1697103   PMID:7510957   PMID:7867896   PMID:7901004   PMID:7901452   PMID:8094989   PMID:8095446  
PMID:8096378   PMID:8100214   PMID:9096350   PMID:9382709   PMID:10087208   PMID:10087302   PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11722849   PMID:12461785  
PMID:12473682   PMID:12477932   PMID:12524683   PMID:12640111   PMID:12788924   PMID:14681479   PMID:14741400   PMID:15138266   PMID:15277520   PMID:15489334   PMID:15609098   PMID:15609325  
PMID:15843371   PMID:16126250   PMID:16141072   PMID:16141073   PMID:16179420   PMID:16192629   PMID:16251195   PMID:16400881   PMID:16602821   PMID:16829211   PMID:17016177   PMID:17543594  
PMID:17608142   PMID:17616686   PMID:18307411   PMID:18440230   PMID:18495459   PMID:18586678   PMID:18835815   PMID:18997394   PMID:19111879   PMID:19165826   PMID:19410608   PMID:19458888  
PMID:19592613   PMID:19661442   PMID:19683237   PMID:19855011   PMID:20181949   PMID:20185832   PMID:20484295   PMID:20956321   PMID:21148317   PMID:21306648   PMID:21509606   PMID:21532881  
PMID:21536655   PMID:21565611   PMID:21591931   PMID:21665949   PMID:21677750   PMID:21690299   PMID:21780244   PMID:21873635   PMID:21979435   PMID:22159717   PMID:22417325   PMID:22572217  
PMID:22685574   PMID:22699122   PMID:22906538   PMID:23395997   PMID:23413430   PMID:23649089   PMID:23856251   PMID:24006456   PMID:24113189   PMID:24120383   PMID:24583261   PMID:24614111  
PMID:24650661   PMID:24990180   PMID:25348956   PMID:25416119   PMID:25715398   PMID:25715693   PMID:25807483   PMID:25924936   PMID:25988230   PMID:26017313   PMID:26258612   PMID:26260798  
PMID:26437801   PMID:26497171   PMID:26700732   PMID:26893379   PMID:26954549   PMID:27432961   PMID:27606829   PMID:27645581   PMID:28010122   PMID:28106301   PMID:28285904   PMID:28452589  
PMID:28522596   PMID:28538980   PMID:28550176   PMID:28624291   PMID:28800626   PMID:29242607   PMID:29530978   PMID:29579155   PMID:29758265   PMID:30044535   PMID:30388216   PMID:30389913  
PMID:30550785   PMID:30595533   PMID:30876926   PMID:30890638   PMID:30939949   PMID:31211696   PMID:32586976   PMID:32913205  


Genomics

Comparative Map Data
Lox
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391852,649,132 - 52,662,939 (-)NCBIGRCm39mm39
GRCm39 Ensembl1852,649,139 - 52,662,939 (-)Ensembl
GRCm381852,516,060 - 52,529,867 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1852,516,067 - 52,529,867 (-)EnsemblGRCm38mm10GRCm38
MGSCv371852,676,892 - 52,689,362 (-)NCBIGRCm37mm9NCBIm37
MGSCv361852,641,436 - 52,655,072 (-)NCBImm8
Celera1853,829,941 - 53,842,352 (-)NCBICelera
Cytogenetic Map18D1NCBI
cM Map1828.22NCBI
LOX
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl5122,063,195 - 122,078,413 (-)EnsemblGRCh38hg38GRCh38
GRCh385122,063,195 - 122,078,259 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh375121,398,890 - 121,413,954 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 365121,429,918 - 121,441,853 (-)NCBINCBI36hg18NCBI36
Build 345121,429,917 - 121,441,853NCBI
Celera5117,353,346 - 117,368,512 (-)NCBI
Cytogenetic Map5q23.1NCBI
HuRef5116,590,466 - 116,605,632 (-)NCBIHuRef
CHM1_15120,831,494 - 120,846,659 (-)NCBICHM1_1
Lox
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21845,964,311 - 46,041,477 (-)NCBI
Rnor_6.0 Ensembl1847,500,330 - 47,577,819 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01847,500,320 - 47,577,819 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01846,713,533 - 46,791,367 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41847,896,674 - 47,970,829 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11847,931,499 - 47,944,296 (-)NCBI
Celera1844,155,712 - 44,229,997 (-)NCBICelera
Cytogenetic Map18q11NCBI
Lox
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955521185,792 - 193,926 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955521178,290 - 193,926 (-)NCBIChiLan1.0ChiLan1.0
LOX
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.15123,233,359 - 123,248,658 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5123,234,662 - 123,248,717 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v05117,450,833 - 117,464,957 (-)NCBIMhudiblu_PPA_v0panPan3
LOX
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11112,023,645 - 12,040,015 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1112,027,250 - 12,039,819 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1110,807,698 - 10,821,728 (-)NCBI
ROS_Cfam_1.01112,730,282 - 12,744,862 (-)NCBI
UMICH_Zoey_3.11111,471,714 - 11,486,299 (-)NCBI
UNSW_CanFamBas_1.01111,289,217 - 11,303,248 (-)NCBI
UU_Cfam_GSD_1.01111,920,314 - 11,934,905 (-)NCBI
Lox
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213134,444,800 - 134,452,726 (-)NCBI
SpeTri2.0NW_0049365752,526,067 - 2,533,996 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LOX
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2125,593,116 - 125,607,594 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12125,595,115 - 125,607,026 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22130,888,135 - 130,900,048 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LOX
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12325,158,458 - 25,172,763 (-)NCBI
ChlSab1.1 Ensembl2325,157,269 - 25,172,757 (-)Ensembl
Vero_WHO_p1.0NW_02366603453,042,867 - 53,057,523 (+)NCBI
Lox
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462477420,116,625 - 20,137,767 (+)NCBI

Position Markers
RH134457  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381852,516,097 - 52,516,276UniSTSGRCm38
MGSCv371852,675,751 - 52,675,930UniSTSGRCm37
Celera1853,828,800 - 53,828,979UniSTS
Cytogenetic Map18D1UniSTS
cM Map1829.0UniSTS
AI893619  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381852,516,115 - 52,516,255UniSTSGRCm38
MGSCv371852,675,769 - 52,675,909UniSTSGRCm37
Celera1853,828,818 - 53,828,958UniSTS
Cytogenetic Map18D1UniSTS
cM Map1829.0UniSTS
Whitehead/MRC_RH18728.35UniSTS
L04262  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381852,517,618 - 52,517,781UniSTSGRCm38
MGSCv371852,677,272 - 52,677,435UniSTSGRCm37
Celera1853,830,321 - 53,830,484UniSTS
Cytogenetic Map18D1UniSTS
cM Map1829.0UniSTS
Whitehead/MRC_RH18733.63UniSTS
Whitehead_YAC18 UniSTS
D18Mit74  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381852,525,560 - 52,525,779UniSTSGRCm38
MGSCv371852,685,214 - 52,685,433UniSTSGRCm37
Celera1853,838,240 - 53,838,423UniSTS
Cytogenetic Map18D1UniSTS
cM Map1825.0UniSTS
Whitehead Genetic1816.4UniSTS
PMC153489P3  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381852,516,712 - 52,517,233UniSTSGRCm38
MGSCv371852,676,366 - 52,676,887UniSTSGRCm37
Celera1853,829,415 - 53,829,936UniSTS
Cytogenetic Map18D1UniSTS
cM Map1829.0UniSTS
Lox  
Mouse AssemblyChrPosition (strand)SourceJBrowse
MGSCv371852,675,812 - 52,676,465UniSTSGRCm37
MGSCv371852,677,444 - 52,677,528UniSTSGRCm37
Celera1853,828,861 - 53,829,514UniSTS
Celera1853,830,493 - 53,830,577UniSTS
Cytogenetic Map18D1UniSTS
cM Map1829.0UniSTS
cM Map1829.0UniSTS
L04262  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381852,518,434 - 52,518,517UniSTSGRCm38
MGSCv371852,678,088 - 52,678,171UniSTSGRCm37
Celera1853,831,137 - 53,831,220UniSTS
Cytogenetic Map18D1UniSTS
Whitehead/MRC_RH18733.63UniSTS
Lox  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381852,516,158 - 52,516,811UniSTSGRCm38
MGSCv371852,675,812 - 52,676,465UniSTSGRCm37
Celera1853,828,861 - 53,829,514UniSTS
Cytogenetic Map18D1UniSTS
cM Map1829.0UniSTS
Lox  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381852,517,790 - 52,517,874UniSTSGRCm38
MGSCv371852,677,444 - 52,677,528UniSTSGRCm37
Celera1853,830,493 - 53,830,577UniSTS
Cytogenetic Map18D1UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
27226723Tibw9_mtibia width 9, proximal, 16 week (mouse)18320000060800000Mouse
1558849W3q15_mweight 3 weeks QTL 15 (mouse)Not determined18504111961139571Mouse
1357603Mom3_mmodifier of Min 3 (mouse)Not determined181389696666965891Mouse
1558743Kcal1_mkilocalorie 1 (mouse)Not determined181888582152885939Mouse
1300638Im7_mimmunoregulatory 7 (mouse)Not determined181888582152885939Mouse
11532709Sluc41_msusceptibility to lung cancer 41 (mouse)182082063757457636Mouse
13463476Hctq8_mhematocrit QTL 8 (mouse)182108452755084674Mouse
1301570Sluc14_msusceptibility to lung cancer 14 (mouse)Not determined182248686156487074Mouse
1300877Adip8_madiposity 8 (mouse)Not determined182248686156487074Mouse
11532710Sluc41a_msusceptibility to lung cancer 41a (mouse)182248686156487074Mouse
11532715Sluc41b_msusceptibility to lung cancer 41b (mouse)182248686156487074Mouse
11532716Sluc41c_msusceptibility to lung cancer 41c (mouse)182248686156487074Mouse
4142031Moen1_mmodifier of engrailed QTL 1 (mouse)Not determined182398250757982677Mouse
25823173Hrsq12_mhost response to SARS QTL 12, hemorrhage (mouse)182476282478296340Mouse
12904950Smmq3_msoleus muscle mass QTL 3 (mouse)182592381059923810Mouse
25823167Hrsq5_mhost response to SARS QTL 5, D3% weight (mouse)182710806258694005Mouse
25823171Hrsq10_mhost response to SARS QTL 10, D4% weight (mouse)182710806258694005Mouse
25823174Hrsq11_mhost response to SARS QTL 11, log titer (mouse)182710806258694005Mouse
1301400Lmr13_mleishmaniasis resistance 13 (mouse)Not determined182797631361976451Mouse
4141857Mhysq5_mmale hybrid sterility QTL 5 (mouse)Not determined2799753761997672Mouse
1302163Bmd16_mbone mineral density 16 (mouse)Not determined182953484763534993Mouse
12880412V125Dq12_mvitamin D active form serum level QTL 12 (mouse)183010000064100000Mouse
1300685Scc5_mcolon tumor susceptibility 5 (mouse)Not determined183185541365855562Mouse
1357690Vtbt19_mvertebral trabecular bone trait 19 (mouse)Not determined183295797666958154Mouse
1301771Pcyts6_mplasmacytoma susceptibility 6 (mouse)Not determined183552556069525779Mouse
4142366Chlq10_mcirculating hormone level QTL 10 (mouse)Not determined183615795070158108Mouse
15039381Ltgq8_mliver triglyceride QTL 8 (mouse)183807349772073497Mouse
15039383Mvlq5_mmicrovesicular liver lesion QTL 5 (mouse)183807349772073497Mouse
15039384Liviq1_mliver inflammation QTL 1 (mouse)183807349772073497Mouse
15039386Mvlq4_mmacrovesicular liver lesion QTL 4 (mouse)183807349772073497Mouse
12050070Nabq2_mnasal bone morphology QTL 2 (mouse)183897060572970721Mouse
1357639Obsty4_mobesity 4 (mouse)Not determined183948686184620653Mouse
1301902Hrtfm4_mheart failure modifier 4 (mouse)Not determined184317804877178271Mouse
1301215Thcr_mT helper cell response (mouse)Not determined184499753768645706Mouse
12904745Carcdq2_mcardiac collagen deposition QTL 2 (mouse)184629021680290216Mouse
10412184Sstapa1_mSuseptibility to Staphylococus aureus infection 1 (mouse)Not determined184640847957457636Mouse
11039493Ltpr8d_mLeishmania tropica response 8d (mouse)184674183280741971Mouse
11039494Ltpr8b_mLeishmania tropica response 8b (mouse)184674183280741971Mouse
27226720Tibw5_mtibia width 5, proximal, 10 week (mouse)185030000062500000Mouse
1357630Tgq1_mtriglyceride QTL 1 (mouse)Not determined185091908584919240Mouse
11252137Modvl5_mmodifier of vacuolated lens 5 (mouse)185091908584919240Mouse
1302099Hdlq30_mHDL QTL 30 (mouse)Not determined185153522985535397Mouse
10412244Par5_mpulmonary adenoma resistance 5 (mouse)Not determined185153522985535397Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1724
Count of miRNA genes:530
Interacting mature miRNAs:658
Transcripts:ENSMUST00000025409, ENSMUST00000171470
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001286181 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001286182 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_010728 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC109203 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC161119 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH003558 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK135213 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK141995 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK159199 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK159241 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK159263 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK159368 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK159682 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK159796 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK160096 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK164634 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK166279 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK166386 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK166442 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BB840428 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC018439 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BQ033730 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466528 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D10837 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M35796 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M65142 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M65143 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000025409   ⟹   ENSMUSP00000025409
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1852,516,067 - 52,529,674 (-)Ensembl
RefSeq Acc Id: ENSMUST00000171470   ⟹   ENSMUSP00000129247
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1852,516,069 - 52,529,867 (-)Ensembl
RefSeq Acc Id: NM_001286181   ⟹   NP_001273110
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391852,649,132 - 52,662,793 (-)NCBI
GRCm381852,516,060 - 52,529,721 (-)NCBI
Celera1853,828,763 - 53,842,511 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001286182   ⟹   NP_001273111
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391852,649,132 - 52,662,939 (-)NCBI
GRCm381852,516,060 - 52,529,867 (-)NCBI
Celera1853,828,763 - 53,842,511 (-)NCBI
Sequence:
RefSeq Acc Id: NM_010728   ⟹   NP_034858
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391852,649,132 - 52,662,895 (-)NCBI
GRCm381852,516,060 - 52,529,823 (-)NCBI
MGSCv371852,676,892 - 52,689,362 (-)RGD
Celera1853,828,763 - 53,842,511 (-)NCBI
cM Map18 ENTREZGENE
Sequence:
Reference Sequences
RefSeq Acc Id: NP_034858   ⟸   NM_010728
- Peptide Label: preproprotein
- UniProtKB: P28301 (UniProtKB/Swiss-Prot),   Q3TP83 (UniProtKB/TrEMBL),   Q3TXH3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001273111   ⟸   NM_001286182
- Peptide Label: preproprotein
- UniProtKB: P28301 (UniProtKB/Swiss-Prot),   Q3TP83 (UniProtKB/TrEMBL),   Q3TXH3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001273110   ⟸   NM_001286181
- Peptide Label: preproprotein
- UniProtKB: P28301 (UniProtKB/Swiss-Prot),   Q3TP83 (UniProtKB/TrEMBL),   Q3TXH3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000129247   ⟸   ENSMUST00000171470
RefSeq Acc Id: ENSMUSP00000025409   ⟸   ENSMUST00000025409

Promoters
RGD ID:13677792
Promoter ID:EPDNEW_M23045
Type:initiation region
Name:Lox_1
Description:Mus musculus lysyl oxidase , transcript variant 3, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381852,529,603 - 52,529,663EPDNEW
RGD ID:6829346
Promoter ID:MM_KWN:25286
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Lung,   MEF_B4,   MEF_B6
Transcripts:ENSMUST00000025409,   NM_010728,   UC008EXF.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361852,688,461 - 52,690,292 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:96817 AgrOrtholog
Ensembl Genes ENSMUSG00000024529 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSMUSP00000025409 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000129247 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000025409 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000171470 ENTREZGENE, UniProtKB/Swiss-Prot
InterPro Lysyl_oxidase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Lysyl_oxidase_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:16948 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:96817 ENTREZGENE
NCBI Gene 16948 ENTREZGENE
Pfam Lysyl_oxidase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Lox PhenoGen
PRINTS LYSYLOXIDASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE LYSYL_OXIDASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt LYOX_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q3TLP7_MOUSE UniProtKB/TrEMBL
  Q3TP83 ENTREZGENE, UniProtKB/TrEMBL
  Q3TWI1_MOUSE UniProtKB/TrEMBL
  Q3TX90_MOUSE UniProtKB/TrEMBL
  Q3TXH3 ENTREZGENE, UniProtKB/TrEMBL
  Q3UXV2_MOUSE UniProtKB/TrEMBL