Bw188 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL Registration

QTL: Bw188 (Body weight QTL 188) Rattus norvegicus

Symbol: Bw188
Name: Body weight QTL 188
RGD ID: 12904668
Previously known as: BpcakmC18QTL2
Trait: body mass   (VT:0001259)    
Measurement Type: body weight   (CMO:0000012)    
LOD Score: Not Available
P Value: 0.03
Variance: Not Available
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81826,822,186 - 71,822,186RGD_MAPPER_PIPELINE
mRatBN7.21826,548,082 - 46,969,551RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01827,743,024 - 48,499,517RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01827,453,116 - 47,711,248RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.41827,430,874 - 49,015,091RGD_MAPPER_PIPELINERGSC3.4
Cross Type: Not Available
Strains Crossed: SS.LEW-(D18Chm41-D18Rat92)/Ayd 
JBrowse: View Region in Genome Browser (JBrowse)
Model




  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bw188Rathypertension  IAGP 1599557 RGD 

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bw188Ratabnormal body weight  IAGP 1599557 RGD 

Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bw188Ratbody weight  IDA 1599557 RGD 

Experimental Condition
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bw188Ratcontrolled sodium content diet  IDA 1599557 RGD 

Measurement Method
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bw188Ratscale  IDA 1599557 RGD 

Rat Strain
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bw188RatSS.LEW-(D18Chm41-D18Rat92)/Ayd  IEA 1599557 RGD 

Vertebrate Trait
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bw188Ratbody mass  IDA 1599557 RGD 


#
Reference Title
Reference Citation
1. Distinct quantitative trait loci for kidney, cardiac, and aortic mass dissociated from and associated with blood pressure in Dahl congenic rats. Duong C, etal., Mamm Genome. 2006 Dec;17(12):1147-61. Epub 2006 Dec 1.


1 to 20 of 299 rows
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
1311806Hspa9heat shock protein family A (Hsp70) member 9182653613126554294Rat
41150603LOC120098310mucin-6-like182657999326594636Rat
11514929LOC108353164uncharacterized LOC108353164182670856326728317Rat
1359485Ctnna1catenin alpha 1182672824626860911Rat
40929473LOC120098430U6 spliceosomal RNA182673841626738522Rat
41166828Trnap-agg77transfer RNA proline (anticodon AGG) 77182675270626752780Rat
1593785Lrrtm2leucine rich repeat transmembrane neuronal 2182681781626822864Rat
735103Sil1SIL1 nucleotide exchange factor182687242327104365Rat
41054661LOC120098407small nucleolar RNA U13182691710726917200Rat
7650468LOC102550858uncharacterized LOC102550858182710449427110858Rat
41199427LOC120098220uncharacterized LOC120098220182713097927140288Rat
3052Matr3matrin 3182715409827193212Rat
4888598Mir1949microRNA 1949182715559527155691Rat
40940619Snora74asmall nucleolar RNA, H/ACA box 74A182715776527157961Rat
5130376Snhg4small nucleolar RNA host gene 4 (non-protein coding)182715843327158669Rat
1359176Paip2poly(A) binding protein interacting protein 2182719976227218359Rat
619875Slc23a1solute carrier family 23 member 1182721494027230564Rat
1310251Mzb1marginal zone B and B1 cell-specific protein182723899927241060Rat
1594845Prob1proline-rich basic protein 1182724251127247355Rat
1311742Spata24spermatogenesis associated 24182724904727257129Rat

1 to 20 of 299 rows
1 to 20 of 313 rows
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Expected Size
Chr
Start
Stop
Species
Match
10689D18Mit5122183135940831359530Ratregion
11337D18Wox9242183586942035869662Ratregion
33577D18Mit1585182730725627307341Ratregion
37524D18Rat63251182754179827542049Ratregion
35491D18Rat22119183041899130419110Ratregion
35495D18Rat35175182802602128026196Ratregion
36914D18Rat18172184671876346718935Ratregion
37608D18Rat53251184050328140503530Ratregion
37910D18Rat71122183007625430076376Ratregion
37958D18Rat68110182696842226968532Ratregion
36444D18Rat21151184262326442623417Ratregion
35020D18Rat36321182768042127680742Ratregion
38366D18Rat59202182805046428050665Ratregion
40326D18Rat97180184032466240325061Ratregion
40326D18Rat97180184032488540325019Ratregion
40326D18Rat97180184032488540325061Ratregion
39294D18Rat51173183024674330246916Ratregion
39444D18Rat96243183962133939621586Ratregion
39550D18Rat100211182960700129607214Ratregion
42424D18Rat150148182812729328127441Ratregion
1 to 20 of 313 rows

Flank 1: (D18Rat101)
Rat AssemblyChrPosition (strand)Source
GRCr81826,822,186 - 26,822,399 (+)Marker Load Pipeline
mRatBN7.21826,548,082 - 26,548,295 (+)MAPPER
Rnor_6.01827,743,024 - 27,743,236NCBI
Rnor_5.01827,453,116 - 27,453,328UniSTS
RGSC_v3.41827,430,874 - 27,431,087RGD
RGSC_v3.41827,430,875 - 27,431,087UniSTS
RGSC_v3.11827,457,520 - 27,457,733RGD
Celera1826,284,754 - 26,284,966UniSTS
RH 2.0 Map18543.4RGD
SHRSP x BN Map1811.4999RGD
Cytogenetic Map18p12UniSTS
Flank 2: (D18Chm56)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21846,969,392 - 46,969,551 (+)MAPPER
Rnor_6.01848,499,359 - 48,499,517NCBI
Rnor_5.01847,711,090 - 47,711,248UniSTS
RGSC_v3.41849,014,933 - 49,015,091UniSTS
Celera1845,150,625 - 45,150,783UniSTS
Cytogenetic Map18q11UniSTS


1 to 10 of 71 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1331733Bp233Blood pressure QTL 2333.97196arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)182479697779788953Rat
1358358Sradr6Stress Responsive Adrenal Weight QTL 62.49adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)181194429959330563Rat
1331735Rf44Renal function QTL 442.981urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)181823456431359530Rat
1331741Bp232Blood pressure QTL 2323.59112arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)182137289383213037Rat
1331742Bp228Blood pressure QTL 2283.88752arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183135940859796643Rat
1331736Bp227Blood pressure QTL 2272.791arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)184671876359796643Rat
12904668Bw188Body weight QTL 1880.03body mass (VT:0001259)body weight (CMO:0000012)182654808246969551Rat
12904669Cm125Cardiac mass QTL 1250.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)182654808246969551Rat
12904670Cm126Cardiac mass QTL 1260.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)182654808246969551Rat
6893683Bw110Body weight QTL 1102.70.002body mass (VT:0001259)body weight (CMO:0000012)184334502283828827Rat

1 to 10 of 71 rows


Note Type Note Reference
qtl_general number of animals used: 5 gender: male 1599557
qtl_general also affects kidney mass, blood pressure, heart left and right ventricle mass, aortic mass and cardiac mass 1599557
qtl_statistics_details software package used: ANOVA followed by Dunnett test in the SYSTAT 9 program 1599557
qtl_trait_method measurement method: selected males were weaned at 21 days of age, then fed a 2% NaCl diet starting from 35 days of age; at 14 weeks animals were weighed 1599557