Predicted to have Atg8 ligase activity. Involved in autophagy. Localizes to the membrane and protein-containing complex. Orthologous to human ATG12 (autophagy related 12); PARTICIPATES IN autophagy pathway; Retinoic acid-inducible gene (RIG) I-like receptor signaling pathway; INTERACTS WITH 4-nonylphenol; bisphenol A; enniatin.
DAPK2 protein affects the reaction [Tretinoin promotes the reaction [ATG5 protein binds to ATG12 protein]], Tretinoin promotes the reaction [ATG5 protein binds to ATG12 protein]
ATG5 protein affects the reaction [Paraquat results in increased expression of [ATG5 protein binds to ATG12 protein]], Paraquat results in increased expression of [ATG5 protein binds to ATG12 protein]
Maneb promotes the reaction [Paraquat results in increased expression of ATG12 protein], Paraquat results in increased expression of [ATG5 protein binds to ATG12 protein]
[Diquat co-treated with procyanidin B2] results in increased expression of ATG12 mRNA, [Hydrogen Peroxide co-treated with procyanidin B2] results in increased expression of ATG12 mRNA
Acetylcysteine inhibits the reaction [vorinostat promotes the reaction [ATG5 protein binds to ATG12 protein]], vorinostat promotes the reaction [ATG5 protein binds to ATG12 protein]
Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Gene-Chemical Interaction Annotations
