(+)-Tetrandrine increases expression ISO RGD:1314851 6480464 tetrandrine results in increased expression of ATG12 protein CTD PMID:26822499 1,2-dichloroethane decreases expression ISO RGD:1558563 6480464 ethylene dichloride results in decreased expression of ATG12 mRNA CTD PMID:28960355 1,2-dimethylhydrazine decreases expression ISO RGD:1558563 6480464 1, 2-Dimethylhydrazine results in decreased expression of ATG12 mRNA CTD PMID:22206623 1,2-dimethylhydrazine multiple interactions ISO RGD:1558563 6480464 [1, 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ATG12 mRNA CTD PMID:22206623 17alpha-ethynylestradiol multiple interactions ISO RGD:1558563 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of ATG12 mRNA CTD PMID:17942748 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:1558563 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of ATG12 mRNA CTD PMID:17942748 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:1558563 6480464 Tetrachlorodibenzodioxin affects the expression of ATG12 mRNA CTD PMID:21570461 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:1558563 6480464 Tetrachlorodibenzodioxin results in decreased expression of ATG12 mRNA CTD PMID:19770486 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:1558563 6480464 Tetrachlorodibenzodioxin results in increased expression of ATG12 mRNA CTD PMID:15328365 3-chloropropane-1,2-diol increases expression EXP 6480464 alpha-Chlorohydrin results in increased expression of ATG12 protein CTD PMID:34915118 4-nonylphenol increases expression EXP 6480464 4-nonylphenol results in increased expression of ATG12 mRNA CTD PMID:28041982 , PMID:30228064 5-fluorouracil decreases expression ISO RGD:1314851 6480464 Fluorouracil results in decreased expression of ATG12 mRNA CTD PMID:16510598 acrolein multiple interactions ISO RGD:1314851 6480464 Acetylcysteine inhibits the reaction [Acrolein results in increased expression of ATG12 protein] CTD PMID:30205151 acrolein increases expression ISO RGD:1314851 6480464 Acrolein results in increased expression of ATG12 protein CTD PMID:30205151 aflatoxin B1 decreases methylation ISO RGD:1314851 6480464 Aflatoxin B1 results in decreased methylation of ATG12 gene CTD PMID:27153756 alginic acid increases expression ISO RGD:1558563 6480464 Alginic Acid results in increased expression of ATG12 protein CTD PMID:35066102 all-trans-retinoic acid multiple interactions ISO RGD:1314851 6480464 DAPK2 protein affects the reaction [Tretinoin promotes the reaction [ATG5 protein binds to ATG12 protein]], Tretinoin promotes the reaction [ATG5 protein binds to ATG12 protein] CTD PMID:28978663 alpha,alpha-trehalose increases expression ISO RGD:1558563 6480464 Trehalose results in increased expression of ATG12 mRNA CTD PMID:30335591 arsenite(3-) decreases expression ISO RGD:1558563 6480464 arsenite results in decreased expression of ATG12 mRNA CTD PMID:33053406 arsenite(3-) multiple interactions ISO RGD:1314851 6480464 arsenite promotes the reaction [G3BP1 protein binds to ATG12 mRNA] CTD PMID:32406909 arsenous acid multiple interactions ISO RGD:1314851 6480464 Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of ATG12 mRNA] more ... CTD PMID:28978663 , PMID:29307831 arsenous acid multiple interactions ISO RGD:1558563 6480464 TFEB protein affects the reaction [Arsenic Trioxide results in increased expression of ATG12 protein] CTD PMID:33462182 arsenous acid increases expression ISO RGD:1314851 6480464 Arsenic Trioxide results in increased expression of ATG12 mRNA CTD PMID:29307831 arsenous acid increases expression ISO RGD:1558563 6480464 Arsenic Trioxide results in increased expression of ATG12 mRNA, Arsenic Trioxide results in increased expression of ATG12 protein CTD PMID:30032600 more ... artesunate increases expression ISO RGD:1314851 6480464 Artesunate results in increased expression of ATG12 mRNA CTD PMID:30551460 astaxanthin multiple interactions ISO RGD:1314851 6480464 astaxanthine inhibits the reaction [bisphenol A results in increased expression of ATG12 mRNA] CTD PMID:34439521 atrazine decreases expression ISO RGD:1314851 6480464 Atrazine results in decreased expression of ATG12 mRNA CTD PMID:22378314 atrazine increases expression EXP 6480464 Atrazine results in increased expression of ATG12 mRNA, Atrazine results in increased expression of ATG12 protein CTD PMID:30084861 benzo[a]pyrene increases expression ISO RGD:1558563 6480464 Benzo(a)pyrene results in increased expression of ATG12 mRNA CTD PMID:22228805 benzo[a]pyrene diol epoxide I decreases expression ISO RGD:1314851 6480464 7 more ... CTD PMID:20018196 bisphenol A increases expression ISO RGD:1558563 6480464 bisphenol A results in increased expression of ATG12 mRNA CTD PMID:26746108 bisphenol A increases expression ISO RGD:1314851 6480464 bisphenol A results in increased expression of ATG12 mRNA CTD PMID:34439521 bisphenol A multiple interactions ISO RGD:1314851 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [bisphenol A results in increased expression of ATG12 mRNA] more ... CTD PMID:34439521 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of ATG12 mRNA CTD PMID:27539358 more ... butanal decreases expression ISO RGD:1314851 6480464 butyraldehyde results in decreased expression of ATG12 mRNA CTD PMID:26079696 cadmium atom increases expression ISO RGD:1558563 6480464 Cadmium results in increased expression of ATG12 mRNA CTD PMID:27492225 cadmium dichloride increases expression ISO RGD:1314851 6480464 Cadmium Chloride results in increased expression of ATG12 protein CTD PMID:33127495 cannabidiol multiple interactions ISO RGD:1558563 6480464 Cannabidiol inhibits the reaction [DMD gene mutant form results in decreased expression of ATG12 mRNA] CTD PMID:30074247 Cannabidivarin multiple interactions ISO RGD:1558563 6480464 cannabidivarin inhibits the reaction [DMD gene mutant form results in decreased expression of ATG12 mRNA] CTD PMID:30074247 carbamazepine affects expression ISO RGD:1314851 6480464 Carbamazepine affects the expression of ATG12 mRNA CTD PMID:25979313 carbon nanotube decreases expression ISO RGD:1314851 6480464 Nanotubes, Carbon results in decreased expression of ATG12 mRNA CTD PMID:30802478 CGP 52608 multiple interactions ISO RGD:1314851 6480464 CGP 52608 promotes the reaction [RORA protein binds to ATG12 gene] CTD PMID:28238834 chloramphenicol increases expression ISO RGD:1314851 6480464 Chloramphenicol results in increased expression of ATG12 mRNA CTD PMID:17457038 chlorpyrifos multiple interactions ISO RGD:1558563 6480464 [Paraquat co-treated with Chlorpyrifos] results in increased expression of ATG12 protein CTD PMID:26884967 cisplatin decreases expression ISO RGD:1558563 6480464 Cisplatin results in decreased expression of ATG12 mRNA CTD PMID:21151649 cobalt dichloride multiple interactions ISO RGD:1314851 6480464 [cobaltous chloride co-treated with TP53 gene mutant form] results in increased expression of ATG12 protein CTD PMID:23380477 cobalt dichloride increases expression ISO RGD:1314851 6480464 cobaltous chloride results in increased expression of ATG12 mRNA CTD PMID:19376846 copper(II) sulfate increases expression ISO RGD:1314851 6480464 Copper Sulfate results in increased expression of ATG12 mRNA CTD PMID:19549813 Curcumol multiple interactions EXP 6480464 curcumol inhibits the reaction [VEGFA protein results in increased expression of ATG12 mRNA] CTD PMID:33549628 cypermethrin increases expression ISO RGD:1314851 6480464 cypermethrin results in increased expression of ATG12 mRNA CTD PMID:27704156 diarsenic trioxide increases expression ISO RGD:1314851 6480464 Arsenic Trioxide results in increased expression of ATG12 mRNA CTD PMID:29307831 diarsenic trioxide multiple interactions ISO RGD:1558563 6480464 TFEB protein affects the reaction [Arsenic Trioxide results in increased expression of ATG12 protein] CTD PMID:33462182 diarsenic trioxide increases expression ISO RGD:1558563 6480464 Arsenic Trioxide results in increased expression of ATG12 mRNA, Arsenic Trioxide results in increased expression of ATG12 protein CTD PMID:30032600 more ... diarsenic trioxide multiple interactions ISO RGD:1314851 6480464 Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of ATG12 mRNA] more ... CTD PMID:28978663 , PMID:29307831 dicrotophos decreases expression ISO RGD:1314851 6480464 dicrotophos results in decreased expression of ATG12 mRNA CTD PMID:28302478 dioxygen multiple interactions ISO RGD:1558563 6480464 [sulforaphane affects the susceptibility to Oxygen] which affects the expression of ATG12 mRNA CTD PMID:30529165 diquat multiple interactions ISO RGD:1558563 6480464 [Diquat co-treated with procyanidin B2] results in increased expression of ATG12 mRNA CTD PMID:27057282 doxorubicin increases expression ISO RGD:1314851 6480464 Doxorubicin results in increased expression of ATG12 protein CTD PMID:31226464 doxorubicin affects expression ISO RGD:1314851 6480464 Doxorubicin affects the expression of ATG12 mRNA CTD PMID:29803840 doxorubicin multiple interactions ISO RGD:1314851 6480464 PQQ Cofactor inhibits the reaction [Doxorubicin results in increased expression of ATG12 protein] CTD PMID:31226464 elemental selenium decreases expression ISO RGD:1314851 6480464 Selenium results in decreased expression of ATG12 mRNA CTD PMID:19244175 embelin multiple interactions ISO RGD:1314851 6480464 embelin results in increased cleavage of [ATG12 protein binds to ATG5 protein] CTD PMID:28722333 enniatin decreases expression EXP 6480464 enniatins results in decreased expression of ATG12 mRNA CTD PMID:27163883 ethanol increases expression ISO RGD:1558563 6480464 Ethanol results in increased expression of ATG12 mRNA CTD PMID:24492484 ethanol affects expression ISO RGD:1558563 6480464 Ethanol affects the expression of ATG12 mRNA CTD PMID:30319688 ethyl methanesulfonate increases expression ISO RGD:1314851 6480464 Ethyl Methanesulfonate results in increased expression of ATG12 mRNA CTD PMID:23649840 fenofibrate increases expression ISO RGD:1558563 6480464 Fenofibrate results in increased expression of ATG12 mRNA CTD PMID:21318169 fenofibrate multiple interactions ISO RGD:1558563 6480464 PPARA protein affects the reaction [Fenofibrate results in increased expression of ATG12 mRNA] CTD PMID:21318169 fenthion decreases expression ISO RGD:1558563 6480464 Fenthion results in decreased expression of ATG12 mRNA CTD PMID:34813904 fingolimod hydrochloride increases expression ISO RGD:1314851 6480464 Fingolimod Hydrochloride results in increased expression of ATG12 protein CTD PMID:25939952 folic acid multiple interactions ISO RGD:1558563 6480464 [1, 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ATG12 mRNA CTD PMID:22206623 formaldehyde increases expression ISO RGD:1314851 6480464 Formaldehyde results in increased expression of ATG12 mRNA CTD PMID:23649840 galangin increases expression ISO RGD:1314851 6480464 galangin results in increased expression of ATG12 mRNA, galangin results in increased expression of ATG12 protein CTD PMID:25268046 galangin multiple interactions ISO RGD:1314851 6480464 [ATG12 mutant form co-treated with galangin] results in decreased activity of CASP3 protein more ... CTD PMID:25268046 gentamycin increases expression EXP 6480464 Gentamicins results in increased expression of ATG12 mRNA CTD PMID:33387578 geraniol multiple interactions ISO RGD:1314851 6480464 geraniol inhibits the reaction [Rotenone results in decreased expression of ATG12 protein] CTD PMID:30141137 glyphosate increases expression ISO RGD:1558563 6480464 glyphosate results in increased expression of ATG12 protein CTD PMID:31352102 glyphosate increases expression ISO RGD:1314851 6480464 glyphosate results in increased expression of ATG12 mRNA CTD PMID:31874349 gossypetin multiple interactions ISO RGD:1314851 6480464 gossypetin promotes the reaction [malondialdehyde-low density lipoprotein, human promotes the reaction [ATG5 protein binds to ATG12 protein]] CTD PMID:25622137 hydrogen peroxide increases expression ISO RGD:1314851 6480464 Hydrogen Peroxide results in increased expression of ATG12 protein CTD PMID:23726866 hydrogen peroxide multiple interactions ISO RGD:1558563 6480464 [Hydrogen Peroxide co-treated with procyanidin B2] results in increased expression of ATG12 mRNA CTD PMID:27057282 ketamine increases expression EXP 6480464 Ketamine results in increased expression of ATG12 mRNA CTD PMID:20080153 lipopolysaccharide increases expression EXP 6480464 Lipopolysaccharides results in increased expression of ATG12 mRNA, Lipopolysaccharides results in increased expression of ATG12 protein CTD PMID:30084861 maneb multiple interactions ISO RGD:1558563 6480464 Maneb promotes the reaction [Paraquat results in increased expression of ATG12 protein] CTD PMID:22292029 methidathion decreases expression ISO RGD:1558563 6480464 methidathion results in decreased expression of ATG12 mRNA CTD PMID:34813904 methotrexate increases expression ISO RGD:1314851 6480464 Methotrexate results in increased expression of ATG12 mRNA CTD PMID:21678067 methyl methanesulfonate increases expression ISO RGD:1314851 6480464 Methyl Methanesulfonate results in increased expression of ATG12 mRNA CTD PMID:23649840 methylparaben increases expression ISO RGD:1314851 6480464 methylparaben results in increased expression of ATG12 mRNA CTD PMID:31745603 N-acetyl-L-cysteine multiple interactions ISO RGD:1314851 6480464 Acetylcysteine inhibits the reaction [Acrolein results in increased expression of ATG12 protein] more ... CTD PMID:20543569 more ... N-acetyl-L-cysteine multiple interactions ISO RGD:1558563 6480464 Acetylcysteine inhibits the reaction [Zinc Oxide analog results in increased expression of ATG12 mRNA] CTD PMID:24614525 N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal multiple interactions ISO RGD:1558563 6480464 [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in increased expression of ATG12 mRNA CTD PMID:25566086 N-ethyl-N-nitrosourea multiple interactions ISO RGD:1558563 6480464 Quercetin inhibits the reaction [Ethylnitrosourea results in decreased expression of ATG12 protein] CTD PMID:32902906 N-ethyl-N-nitrosourea decreases expression ISO RGD:1558563 6480464 Ethylnitrosourea results in decreased expression of ATG12 protein CTD PMID:32902906 nickel atom multiple interactions ISO RGD:1314851 6480464 [Nickel co-treated with austenitic steel analog] results in increased expression of ATG12 mRNA CTD PMID:23638002 Nonidet P-40 increases expression ISO RGD:1314851 6480464 Nonidet P-40 results in increased expression of ATG12 mRNA CTD PMID:26552463 oligopeptide decreases expression ISO RGD:1314851 6480464 Oligopeptides analog results in decreased expression of ATG12 protein CTD PMID:24875536 paracetamol affects expression ISO RGD:1558563 6480464 Acetaminophen affects the expression of ATG12 mRNA CTD PMID:17562736 paracetamol increases expression EXP 6480464 Acetaminophen results in increased expression of ATG12 mRNA CTD PMID:33387578 paracetamol increases expression ISO RGD:1314851 6480464 Acetaminophen results in increased expression of ATG12 mRNA CTD PMID:21420995 paraquat increases expression ISO RGD:1558563 6480464 Paraquat results in increased expression of ATG12 protein CTD PMID:22292029 , PMID:26884967 paraquat multiple interactions ISO RGD:1314851 6480464 ATG5 protein affects the reaction [Paraquat results in increased expression of [ATG5 protein binds to ATG12 protein]], Paraquat results in increased expression of [ATG5 protein binds to ATG12 protein] CTD PMID:22982048 paraquat increases expression ISO RGD:1314851 6480464 Paraquat results in increased expression of ATG12 mRNA CTD PMID:27220436 paraquat multiple interactions ISO RGD:1558563 6480464 [Paraquat co-treated with Chlorpyrifos] results in increased expression of ATG12 protein more ... CTD PMID:22292029 more ... perfluorooctane-1-sulfonic acid increases expression EXP 6480464 perfluorooctane sulfonic acid results in increased expression of ATG12 mRNA CTD PMID:27825932 perfluorooctanoic acid increases expression ISO RGD:1558563 6480464 perfluorooctanoic acid results in increased expression of ATG12 mRNA CTD PMID:26879310 phenobarbital affects expression ISO RGD:1314851 6480464 Phenobarbital affects the expression of ATG12 mRNA CTD PMID:19159669 pirinixic acid multiple interactions ISO RGD:1558563 6480464 PPARA protein affects the reaction [pirinixic acid results in increased expression of ATG12 mRNA] CTD PMID:21318169 pirinixic acid increases expression ISO RGD:1558563 6480464 pirinixic acid results in increased expression of ATG12 mRNA CTD PMID:18301758 more ... procyanidin B2 multiple interactions ISO RGD:1558563 6480464 [Diquat co-treated with procyanidin B2] results in increased expression of ATG12 mRNA, [Hydrogen Peroxide co-treated with procyanidin B2] results in increased expression of ATG12 mRNA CTD PMID:27057282 pyrroloquinoline quinone multiple interactions ISO RGD:1314851 6480464 PQQ Cofactor inhibits the reaction [Doxorubicin results in increased expression of ATG12 protein] CTD PMID:31226464 quercetin multiple interactions ISO RGD:1314851 6480464 Quercetin results in increased expression of [ATG12 protein binds to ATG5 protein] CTD PMID:25293876 quercetin multiple interactions ISO RGD:1558563 6480464 Quercetin inhibits the reaction [Ethylnitrosourea results in decreased expression of ATG12 protein] CTD PMID:32902906 resveratrol multiple interactions ISO RGD:1314851 6480464 [Plant Extracts co-treated with Resveratrol] results in increased expression of ATG12 mRNA CTD PMID:23557933 rotenone multiple interactions ISO RGD:1314851 6480464 geraniol inhibits the reaction [Rotenone results in decreased expression of ATG12 protein] CTD PMID:30141137 rotenone decreases expression ISO RGD:1314851 6480464 Rotenone results in decreased expression of ATG12 protein CTD PMID:30141137 selenium atom decreases expression ISO RGD:1314851 6480464 Selenium results in decreased expression of ATG12 mRNA CTD PMID:19244175 sodium arsenite decreases expression ISO RGD:1314851 6480464 sodium arsenite results in decreased expression of ATG12 mRNA CTD PMID:28595984 sodium arsenite multiple interactions ISO RGD:1558563 6480464 [sodium arsenite co-treated with Dietary Fats] results in increased expression of ATG12 mRNA CTD PMID:30097599 sodium arsenite increases expression ISO RGD:1558563 6480464 sodium arsenite results in increased expression of ATG12 mRNA CTD PMID:30097599 staurosporine affects response to substance ISO RGD:1314851 6480464 ATG12 protein affects the susceptibility to Staurosporine CTD PMID:16497721 streptozocin increases expression ISO RGD:1558563 6480464 Streptozocin results in increased expression of ATG12 mRNA CTD PMID:24889822 sulforaphane multiple interactions ISO RGD:1558563 6480464 [sulforaphane affects the susceptibility to Oxygen] which affects the expression of ATG12 mRNA CTD PMID:30529165 T-2 toxin increases expression ISO RGD:1558563 6480464 T-2 Toxin results in increased expression of ATG12 protein CTD PMID:26138683 tetrachloromethane increases expression ISO RGD:1558563 6480464 Carbon Tetrachloride results in increased expression of ATG12 mRNA CTD PMID:31919559 thymoquinone decreases expression ISO RGD:1314851 6480464 thymoquinone results in decreased expression of ATG12 protein CTD PMID:31298468 torcetrapib increases expression ISO RGD:1314851 6480464 torcetrapib results in increased expression of ATG12 mRNA CTD PMID:23228038 Triptolide increases expression ISO RGD:1558563 6480464 triptolide results in increased expression of ATG12 protein CTD PMID:26990902 triptonide increases expression ISO RGD:1558563 6480464 triptonide results in increased expression of ATG12 mRNA CTD PMID:33045310 trovafloxacin increases expression ISO RGD:1314851 6480464 trovafloxacin results in increased expression of ATG12 mRNA CTD PMID:33609687 trovafloxacin increases expression ISO RGD:1558563 6480464 trovafloxacin results in increased expression of ATG12 mRNA CTD PMID:35537566 valproic acid increases expression ISO RGD:1558563 6480464 Valproic Acid results in increased expression of ATG12 mRNA CTD PMID:20546886 vinclozolin affects expression EXP 6480464 vinclozolin affects the expression of ATG12 mRNA CTD PMID:19015723 vitamin E decreases expression ISO RGD:1314851 6480464 Vitamin E results in decreased expression of ATG12 mRNA CTD PMID:19244175 vorinostat multiple interactions ISO RGD:1314851 6480464 Acetylcysteine inhibits the reaction [vorinostat promotes the reaction [ATG5 protein binds to ATG12 protein]], vorinostat promotes the reaction [ATG5 protein binds to ATG12 protein] CTD PMID:20543569 zinc atom multiple interactions ISO RGD:1314851 6480464 [PCI 5002 co-treated with Zinc] results in increased expression of ATG12 mRNA CTD PMID:18593933 zinc oxide increases expression ISO RGD:1558563 6480464 Zinc Oxide analog results in increased expression of ATG12 mRNA CTD PMID:24614525 zinc oxide multiple interactions ISO RGD:1558563 6480464 Acetylcysteine inhibits the reaction [Zinc Oxide analog results in increased expression of ATG12 mRNA] CTD PMID:24614525 zinc(0) multiple interactions ISO RGD:1314851 6480464 [PCI 5002 co-treated with Zinc] results in increased expression of ATG12 mRNA CTD PMID:18593933
