ATG12 (autophagy related 12) - Rat Genome Database

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Pathways
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Gene: ATG12 (autophagy related 12) Pan paniscus
Analyze
Symbol: ATG12
Name: autophagy related 12
RGD ID: 11686505
Description: INVOLVED IN autophagy (ortholog); macroautophagy (ortholog); negative regulation of defense response to virus (ortholog); PARTICIPATES IN autophagy pathway; ASSOCIATED WITH autistic disorder (ortholog); Brain Injuries (ortholog); familial adenomatous polyposis 1 (ortholog); FOUND IN Atg12-Atg5-Atg16 complex (ortholog); autophagosome (ortholog); intracellular membrane-bounded organelle (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ubiquitin-like protein ATG12
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24111,074,139 - 111,086,535 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15109,227,800 - 109,240,196 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05111,184,617 - 111,196,038 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15116,979,738 - 116,992,288 (-)NCBIpanpan1.1PanPan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
ATG12
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24111,074,139 - 111,086,535 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15109,227,800 - 109,240,196 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05111,184,617 - 111,196,038 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15116,979,738 - 116,992,288 (-)NCBIpanpan1.1PanPan1.1panPan2
ATG12
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385115,828,200 - 115,841,565 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5115,828,200 - 115,841,837 (-)EnsemblGRCh38hg38GRCh38
GRCh375115,163,897 - 115,177,262 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 365115,193,714 - 115,205,398 (-)NCBINCBI36Build 36hg18NCBI36
Build 345115,193,713 - 115,205,398NCBI
Celera5111,112,297 - 111,125,961 (-)NCBICelera
Cytogenetic Map5q22.3NCBI
HuRef5110,344,587 - 110,358,250 (-)NCBIHuRef
CHM1_15114,596,527 - 114,610,191 (-)NCBICHM1_1
T2T-CHM13v2.05116,340,597 - 116,353,961 (-)NCBIT2T-CHM13v2.0
Atg12
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391846,865,484 - 46,874,683 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1846,863,211 - 46,874,647 (-)EnsemblGRCm39 Ensembl
GRCm381846,732,417 - 46,741,724 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1846,730,144 - 46,741,580 (-)EnsemblGRCm38mm10GRCm38
MGSCv371846,892,071 - 46,901,233 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361846,857,758 - 46,866,888 (-)NCBIMGSCv36mm8
Celera1848,091,663 - 48,100,825 (-)NCBICelera
Cytogenetic Map18CNCBI
cM Map1824.76NCBI
Atg12
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81841,638,841 - 41,649,311 (-)NCBIGRCr8
mRatBN7.21839,452,247 - 39,462,424 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1839,452,191 - 39,462,418 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1841,485,451 - 41,495,628 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01842,187,696 - 42,197,873 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01839,980,798 - 39,990,975 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01840,721,799 - 40,732,143 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1840,721,800 - 40,732,126 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01840,367,826 - 40,378,153 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41840,933,793 - 40,943,970 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11840,971,333 - 40,981,496 (-)NCBI
Celera1837,703,672 - 37,713,849 (-)NCBICelera
Cytogenetic Map18q11NCBI
Atg12
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540835,607,541 - 35,620,878 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540835,607,541 - 35,620,878 (-)NCBIChiLan1.0ChiLan1.0
ATG12
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1115,531,062 - 5,543,034 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl115,531,759 - 5,542,743 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha115,681,691 - 5,693,659 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0115,522,868 - 5,534,845 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl115,522,246 - 5,534,875 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1115,478,061 - 5,490,016 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0115,549,224 - 5,561,188 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0115,801,442 - 5,813,410 (-)NCBIUU_Cfam_GSD_1.0
Atg12
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213128,299,258 - 128,306,932 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936742999,771 - 1,007,885 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367421,000,029 - 1,007,885 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ATG12
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2119,941,997 - 119,965,696 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12119,948,443 - 119,965,702 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22124,835,748 - 124,851,487 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ATG12
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12319,073,545 - 19,087,603 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2319,072,401 - 19,087,625 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603459,321,234 - 59,334,961 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Atg12
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247336,045,432 - 6,060,784 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247336,046,073 - 6,056,321 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_024928793   ⟹   XP_024784561
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v24111,077,450 - 111,086,535 (-)NCBI
NHGRI_mPanPan15109,231,111 - 109,240,196 (-)NCBI
Mhudiblu_PPA_v05111,186,812 - 111,195,918 (-)NCBI
PanPan1.15116,983,044 - 116,992,154 (-)NCBI
Sequence:
RefSeq Acc Id: XM_034960369   ⟹   XP_034816260
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v24111,074,139 - 111,086,535 (-)NCBI
NHGRI_mPanPan15109,227,800 - 109,240,196 (-)NCBI
Mhudiblu_PPA_v05111,184,617 - 111,196,038 (-)NCBI
RefSeq Acc Id: XM_063604597   ⟹   XP_063460667
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v24111,077,524 - 111,086,535 (-)NCBI
Protein Sequences
Protein RefSeqs XP_024784561 (Get FASTA)   NCBI Sequence Viewer  
  XP_034816260 (Get FASTA)   NCBI Sequence Viewer  
  XP_063460667 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000028106.1
  ENSPPAP00000028112.1
Reference Protein Sequences
RefSeq Acc Id: XP_024784561   ⟸   XM_024928793
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_034816260   ⟸   XM_034960369
- Peptide Label: isoform X1
- UniProtKB: A0A2R9BIJ9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063460667   ⟸   XM_063604597
- Peptide Label: isoform X2


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000037112 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000050950.1 UniProtKB/TrEMBL
  ENSPPAT00000050956.1 UniProtKB/TrEMBL
InterPro Atg12 UniProtKB/TrEMBL
  Ubiquitin-like_domsf UniProtKB/TrEMBL
NCBI Gene ATG12 ENTREZGENE
PANTHER PTHR13385 UniProtKB/TrEMBL
  UBIQUITIN-LIKE PROTEIN ATG12 UniProtKB/TrEMBL
Pfam APG12 UniProtKB/TrEMBL
Superfamily-SCOP SSF54236 UniProtKB/TrEMBL
UniProt A0A2R9BIJ9 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9BN57_PANPA UniProtKB/TrEMBL