ATG12 (autophagy related 12) - Rat Genome Database

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Pathways
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Gene: ATG12 (autophagy related 12) Sus scrofa
Analyze
Symbol: ATG12
Name: autophagy related 12
RGD ID: 13989279
Description: INVOLVED IN autophagy (ortholog); PARTICIPATES IN autophagy pathway; ASSOCIATED WITH autistic disorder (ortholog); Brain Injuries (ortholog); familial adenomatous polyposis 1 (ortholog); FOUND IN Atg12-Atg5-Atg16 complex (ortholog); protein-containing complex (ortholog)
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: ATG12 autophagy related 12 homolog; ubiquitin-like protein ATG12
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2119,941,997 - 119,965,696 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12119,948,443 - 119,965,702 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22124,835,748 - 124,851,487 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:14681463   PMID:15679890   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
ATG12
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2119,941,997 - 119,965,696 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12119,948,443 - 119,965,702 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22124,835,748 - 124,851,487 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ATG12
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385115,828,200 - 115,841,565 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5115,828,200 - 115,841,837 (-)EnsemblGRCh38hg38GRCh38
GRCh375115,163,897 - 115,177,262 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 365115,193,714 - 115,205,398 (-)NCBINCBI36Build 36hg18NCBI36
Build 345115,193,713 - 115,205,398NCBI
Celera5111,112,297 - 111,125,961 (-)NCBICelera
Cytogenetic Map5q22.3NCBI
HuRef5110,344,587 - 110,358,250 (-)NCBIHuRef
CHM1_15114,596,527 - 114,610,191 (-)NCBICHM1_1
T2T-CHM13v2.05116,340,597 - 116,353,961 (-)NCBIT2T-CHM13v2.0
Atg12
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391846,865,484 - 46,874,683 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1846,863,211 - 46,874,647 (-)EnsemblGRCm39 Ensembl
GRCm381846,732,417 - 46,741,724 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1846,730,144 - 46,741,580 (-)EnsemblGRCm38mm10GRCm38
MGSCv371846,892,071 - 46,901,233 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361846,857,758 - 46,866,888 (-)NCBIMGSCv36mm8
Celera1848,091,663 - 48,100,825 (-)NCBICelera
Cytogenetic Map18CNCBI
cM Map1824.76NCBI
Atg12
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81841,638,841 - 41,649,311 (-)NCBIGRCr8
mRatBN7.21839,452,247 - 39,462,424 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1839,452,191 - 39,462,418 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1841,485,451 - 41,495,628 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01842,187,696 - 42,197,873 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01839,980,798 - 39,990,975 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01840,721,799 - 40,732,143 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1840,721,800 - 40,732,126 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01840,367,826 - 40,378,153 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41840,933,793 - 40,943,970 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11840,971,333 - 40,981,496 (-)NCBI
Celera1837,703,672 - 37,713,849 (-)NCBICelera
Cytogenetic Map18q11NCBI
Atg12
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540835,607,541 - 35,620,878 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540835,607,541 - 35,620,878 (-)NCBIChiLan1.0ChiLan1.0
ATG12
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24111,074,139 - 111,086,535 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15109,227,800 - 109,240,196 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05111,184,617 - 111,196,038 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15116,979,738 - 116,992,288 (-)NCBIpanpan1.1PanPan1.1panPan2
ATG12
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1115,531,062 - 5,543,034 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl115,531,759 - 5,542,743 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha115,681,691 - 5,693,659 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0115,522,868 - 5,534,845 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl115,522,246 - 5,534,875 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1115,478,061 - 5,490,016 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0115,549,224 - 5,561,188 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0115,801,442 - 5,813,410 (-)NCBIUU_Cfam_GSD_1.0
Atg12
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213128,299,258 - 128,306,932 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936742999,771 - 1,007,885 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367421,000,029 - 1,007,885 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ATG12
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12319,073,545 - 19,087,603 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2319,072,401 - 19,087,625 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603459,321,234 - 59,334,961 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Atg12
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247336,045,432 - 6,060,784 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247336,046,073 - 6,056,321 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in ATG12
371 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 9 2 3 5 23 1 3 3
Low 1 2 2 1
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000049974   ⟹   ENSSSCP00000054263
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl2119,941,997 - 119,965,510 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000088479   ⟹   ENSSSCP00000073468
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl2119,949,520 - 119,965,696 (-)Ensembl
RefSeq Acc Id: NM_001190282   ⟹   NP_001177211
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.12119,948,443 - 119,965,702 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_001177211   ⟸   NM_001190282
- UniProtKB: D7RA34 (UniProtKB/TrEMBL),   A0A8D1TFS9 (UniProtKB/TrEMBL),   F1RLE4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000073468   ⟸   ENSSSCT00000088479
RefSeq Acc Id: ENSSSCP00000054263   ⟸   ENSSSCT00000049974


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000033912 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00015012138 UniProtKB/TrEMBL
  ENSSSCG00025041926 UniProtKB/TrEMBL
  ENSSSCG00030061633 UniProtKB/TrEMBL
  ENSSSCG00035066218 UniProtKB/TrEMBL
  ENSSSCG00040071509 UniProtKB/TrEMBL
  ENSSSCG00045009615 UniProtKB/TrEMBL
  ENSSSCG00050041701 UniProtKB/TrEMBL
  ENSSSCG00055008816 UniProtKB/TrEMBL
  ENSSSCG00060006947 UniProtKB/TrEMBL
  ENSSSCG00065009353 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000049974 ENTREZGENE
  ENSSSCT00000049974.2 UniProtKB/TrEMBL
  ENSSSCT00000088479.2 UniProtKB/TrEMBL
  ENSSSCT00015016063.1 UniProtKB/TrEMBL
  ENSSSCT00025056990.1 UniProtKB/TrEMBL
  ENSSSCT00030086158.1 UniProtKB/TrEMBL
  ENSSSCT00030086173.1 UniProtKB/TrEMBL
  ENSSSCT00035089229.1 UniProtKB/TrEMBL
  ENSSSCT00040098353.1 UniProtKB/TrEMBL
  ENSSSCT00045016305.1 UniProtKB/TrEMBL
  ENSSSCT00045016338.1 UniProtKB/TrEMBL
  ENSSSCT00050056601.1 UniProtKB/TrEMBL
  ENSSSCT00050056602.1 UniProtKB/TrEMBL
  ENSSSCT00055017259.1 UniProtKB/TrEMBL
  ENSSSCT00060008881.1 UniProtKB/TrEMBL
  ENSSSCT00065012450.1 UniProtKB/TrEMBL
InterPro Atg12 UniProtKB/TrEMBL
  Ubiquitin-like_domsf UniProtKB/TrEMBL
KEGG Report ssc:100462745 UniProtKB/TrEMBL
NCBI Gene ATG12 ENTREZGENE
PANTHER PTHR13385 UniProtKB/TrEMBL
  UBIQUITIN-LIKE PROTEIN ATG12 UniProtKB/TrEMBL
Pfam APG12 UniProtKB/TrEMBL
Superfamily-SCOP SSF54236 UniProtKB/TrEMBL
UniProt A0A5G2R870_PIG UniProtKB/TrEMBL
  A0A8D1MKU5_PIG UniProtKB/TrEMBL
  A0A8D1TFS9 ENTREZGENE, UniProtKB/TrEMBL
  D7RA34 ENTREZGENE, UniProtKB/TrEMBL
  F1RLE4 ENTREZGENE
UniProt Secondary F1RLE4 UniProtKB/TrEMBL
VGNC ID VGNC:85615 ENTREZGENE