Ecscr (endothelial cell surface expressed chemotaxis and apoptosis regulator) - Rat Genome Database

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Gene: Ecscr (endothelial cell surface expressed chemotaxis and apoptosis regulator) Rattus norvegicus
Analyze
Symbol: Ecscr
Name: endothelial cell surface expressed chemotaxis and apoptosis regulator
RGD ID: 1594804
Description: Predicted to be involved in negative regulation of angiogenesis; positive regulation of endothelial cell apoptotic process; and positive regulation of proteasomal protein catabolic process. Predicted to be located in nucleoplasm. Predicted to be active in cytosol and plasma membrane. Orthologous to human ECSCR (endothelial cell surface expressed chemotaxis and apoptosis regulator); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; paracetamol; thioacetamide.
Type: protein-coding
RefSeq Status: MODEL
Previously known as: apoptosis regulator through modulating IAP expression; Aria; Ecscr-ps1; endothelial cell-specific chemotaxis regulator; endothelial cell-specific chemotaxis regulator, pseudogene 1; hypothetical protein LOC682650; hypothetical protein LOC689248; LOC689248
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21827,309,711 - 27,319,106 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl1827,309,718 - 27,319,032 (-)Ensembl
Rnor_6.01828,507,167 - 28,516,567 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1828,506,934 - 28,516,209 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01828,219,716 - 28,229,043 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41828,328,191 - 28,340,335 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1827,043,217 - 27,052,411 (-)NCBICelera
Cytogenetic Map18p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:19416853   PMID:24338479  


Genomics

Comparative Map Data
Ecscr
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21827,309,711 - 27,319,106 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl1827,309,718 - 27,319,032 (-)Ensembl
Rnor_6.01828,507,167 - 28,516,567 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1828,506,934 - 28,516,209 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01828,219,716 - 28,229,043 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41828,328,191 - 28,340,335 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1827,043,217 - 27,052,411 (-)NCBICelera
Cytogenetic Map18p11NCBI
ECSCR
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385139,448,560 - 139,462,743 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl5139,448,560 - 139,462,743 (-)EnsemblGRCh38hg38GRCh38
GRCh375138,784,249 - 138,842,328 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 365138,817,313 - 138,822,504 (-)NCBINCBI36hg18NCBI36
Celera5134,904,524 - 134,917,004 (-)NCBI
Cytogenetic Map5q31.2NCBI
HuRef5133,976,927 - 133,984,822 (-)NCBIHuRef
HuRef5133,973,970 - 133,974,590 (-)NCBIHuRef
CHM1_15138,269,725 - 138,274,901 (-)NCBICHM1_1
CHM1_15138,216,851 - 138,217,469 (-)NCBICHM1_1
T2T-CHM13v2.05139,974,387 - 139,987,818 (-)NCBI
Ecscr
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391835,846,139 - 35,855,460 (-)NCBIGRCm39mm39
GRCm39 Ensembl1835,846,139 - 35,855,409 (-)Ensembl
GRCm381835,713,086 - 35,722,413 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1835,713,086 - 35,722,356 (-)EnsemblGRCm38mm10GRCm38
MGSCv371835,872,743 - 35,881,145 (-)NCBIGRCm37mm9NCBIm37
MGSCv361835,839,063 - 35,847,465 (-)NCBImm8
Celera1836,169,173 - 36,177,565 (-)NCBICelera
Cytogenetic Map18B2NCBI
Ecscr
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554181,108,805 - 1,116,338 (+)NCBIChiLan1.0ChiLan1.0
ECSCR
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.15140,940,578 - 140,955,137 (-)NCBIpanpan1.1PanPan1.1panPan2
Mhudiblu_PPA_v05134,819,568 - 134,833,508 (-)NCBIMhudiblu_PPA_v0panPan3
ECSCR
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1234,763,814 - 34,773,491 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha231,866,062 - 31,875,564 (-)NCBI
ROS_Cfam_1.0235,219,054 - 35,227,401 (-)NCBI
ROS_Cfam_1.0 Ensembl235,217,688 - 35,243,000 (-)Ensembl
UMICH_Zoey_3.1232,270,349 - 32,279,851 (-)NCBI
UNSW_CanFamBas_1.0233,136,664 - 33,146,167 (-)NCBI
UU_Cfam_GSD_1.0233,889,703 - 33,898,041 (-)NCBI
Ecscr
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213153,068,890 - 153,077,585 (+)NCBI
SpeTri2.0NW_0049365318,533,926 - 8,542,516 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ECSCR
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.12141,343,818 - 141,352,618 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22147,153,633 - 147,162,663 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ECSCR
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12342,124,181 - 42,137,577 (-)NCBIChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603435,750,604 - 35,763,890 (+)NCBIVero_WHO_p1.0
Ecscr
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462474332,248,768 - 32,272,352 (-)NCBIHetGla_female_1.0hetGla2

Position Markers
D18Mit15  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21827,307,256 - 27,307,341 (+)MAPPERmRatBN7.2
Rnor_6.01828,504,713 - 28,504,797NCBIRnor6.0
Rnor_5.01828,217,262 - 28,217,346UniSTSRnor5.0
RGSC_v3.41828,329,665 - 28,329,750RGDRGSC3.4
RGSC_v3.41828,329,666 - 28,329,750UniSTSRGSC3.4
RGSC_v3.11828,356,168 - 28,356,559RGD
Celera1827,040,623 - 27,040,707UniSTS
Cytogenetic Map18p11UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2312598Bp340Blood pressure QTL 3400.05arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)18130558703Rat
2300180Bmd67Bone mineral density QTL 674.80.0001femur mineral mass (VT:0010011)bone mineral density (CMO:0001226)18134291613Rat
2293661Bss50Bone structure and strength QTL 504.640.0003lumbar vertebra size trait (VT:0010518)lumbar vertebra trabecular cross-sectional area (CMO:0001692)18134291613Rat
61388Bp2Blood pressure QTL 23.23arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)18135374722Rat
9589153Insul31Insulin level QTL 317.150.05blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)18142547119Rat
2299160Iddm35Insulin dependent diabetes mellitus QTL 352.79blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)18420794160377792Rat
2312568Glom21Glomerulus QTL 2120.005kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)18518585840503530Rat
2293708Bss46Bone structure and strength QTL 468.80.0001lumbar vertebra morphology trait (VT:0010494)lumbar vertebra cortical cross-sectional area (CMO:0001690)181179151863636873Rat
1578661Bss20Bone structure and strength QTL 203.7femur morphology trait (VT:0000559)femoral neck cross-sectional area (CMO:0001697)181179151883218561Rat
1578667Bss21Bone structure and strength QTL 213.5femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)181179151883218561Rat
61382Bp46Blood pressure QTL 4618.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)181194179131393320Rat
631264Scl22Serum cholesterol level QTL 226.2blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)181194179131393320Rat
1331766Bp236Blood pressure QTL 2363.022arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)181194429931359530Rat
61375Bp41Blood pressure QTL 412.4blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)181194429941122201Rat
1331753Bp231Blood pressure QTL 2313.643arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)181194429952293055Rat
1358358Sradr6Stress Responsive Adrenal Weight QTL 62.49adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)181194429959330563Rat
6903359Bp355Blood pressure QTL 3553.6arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)181194454459796478Rat
2313082Bss85Bone structure and strength QTL 850.80.0001long bone metaphysis morphology trait (VT:0000133)tibia midshaft total cross-sectional area (CMO:0001715)181495133759951337Rat
1358193Emca2Estrogen-induced mammary cancer QTL 21.6mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)181800759963571040Rat
1331735Rf44Renal function QTL 442.981total urine protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)181823456431359530Rat
1331775Bp235Blood pressure QTL 2353.201arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)181823456431359530Rat
1600373Mamtr6Mammary tumor resistance QTL 6mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)181927890183218561Rat
1331741Bp232Blood pressure QTL 2323.59112arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)182137289383213037Rat
1641923Colcr8Colorectal carcinoma resistance QTL 83.10.0014intestine integrity trait (VT:0010554)poorly differentiated malignant colorectal tumor number (CMO:0002076)182206624252293055Rat
1331733Bp233Blood pressure QTL 2333.97196arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)182479697779788953Rat
2325839Bp348Blood pressure QTL 3480.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)182557098570570985Rat
12904673Cm127Cardiac mass QTL 1270.005heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)182654808246969551Rat
12904675Am19Aortic mass QTL 190.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)182654808246969551Rat
12904677Kidm72Kidney mass QTL 720.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)182654808246969551Rat
12904668Bw188Body weight QTL 1880.03body mass (VT:0001259)body weight (CMO:0000012)182654808246969551Rat
12904669Cm125Cardiac mass QTL 1250.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)182654808246969551Rat
12904670Cm126Cardiac mass QTL 1260.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)182654808246969551Rat
2301413Bp318Blood pressure QTL 3180.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)182654808246969551Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:110
Count of miRNA genes:68
Interacting mature miRNAs:73
Transcripts:ENSRNOT00000060689, ENSRNOT00000072580
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 1 31 20 24 10
Low 2 12 57 41 19 41 8 11 74 15 17 1 8
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000072580   ⟹   ENSRNOP00000067313
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1827,309,765 - 27,318,822 (-)Ensembl
Rnor_6.0 Ensembl1828,506,934 - 28,516,209 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000097911   ⟹   ENSRNOP00000087965
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1827,310,432 - 27,318,747 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000110568   ⟹   ENSRNOP00000088865
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1827,309,765 - 27,317,832 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000120258   ⟹   ENSRNOP00000079454
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1827,309,718 - 27,319,032 (-)Ensembl
RefSeq Acc Id: XM_008772057   ⟹   XP_008770279
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21827,309,711 - 27,318,795 (-)NCBI
Rnor_6.01828,507,167 - 28,516,564 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017601091   ⟹   XP_017456580
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21827,309,711 - 27,318,797 (-)NCBI
Rnor_6.01828,507,167 - 28,516,567 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017601092   ⟹   XP_017456581
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21827,309,711 - 27,318,796 (-)NCBI
Rnor_6.01828,507,167 - 28,516,565 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017601093   ⟹   XP_017456582
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21827,309,711 - 27,319,106 (-)NCBI
Rnor_6.01828,507,167 - 28,516,566 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039097302   ⟹   XP_038953230
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21827,310,432 - 27,318,798 (-)NCBI
Reference Sequences
RefSeq Acc Id: XP_008770279   ⟸   XM_008772057
- Peptide Label: isoform X4
- UniProtKB: M0RCJ4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017456580   ⟸   XM_017601091
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_017456582   ⟸   XM_017601093
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_017456581   ⟸   XM_017601092
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: ENSRNOP00000067313   ⟸   ENSRNOT00000072580
RefSeq Acc Id: XP_038953230   ⟸   XM_039097302
- Peptide Label: isoform X2
RefSeq Acc Id: ENSRNOP00000088865   ⟸   ENSRNOT00000110568
RefSeq Acc Id: ENSRNOP00000079454   ⟸   ENSRNOT00000120258
RefSeq Acc Id: ENSRNOP00000087965   ⟸   ENSRNOT00000097911

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-M0RCJ4-F1-model_v2 AlphaFold M0RCJ4 1-224 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13700716
Promoter ID:EPDNEW_R11237
Type:initiation region
Name:Ecscr_1
Description:endothelial cell surface expressed chemotaxis and apoptosis regulator
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01828,516,172 - 28,516,232EPDNEW

Strain Variation

Strain Sequence Variants (MRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
Damaging Variants


Assembly: Rnor_6.0

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
18 28516145 28516146 C T snv HXB4/IpcvMcwi (2020)


Assembly: mRatBN7.2

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
18 27318690 27318691 C T snv HXB4/IpcvMcwi (2020)


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1594804 AgrOrtholog
BioCyc Gene G2FUF-7896 BioCyc
Ensembl Genes ENSRNOG00000039593 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000067313 ENTREZGENE
  ENSRNOP00000067313.2 UniProtKB/TrEMBL
  ENSRNOP00000079454.1 UniProtKB/TrEMBL
  ENSRNOP00000087965.1 UniProtKB/TrEMBL
  ENSRNOP00000088865.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000072580 ENTREZGENE
  ENSRNOT00000072580.4 UniProtKB/TrEMBL
  ENSRNOT00000097911.1 UniProtKB/TrEMBL
  ENSRNOT00000110568.1 UniProtKB/TrEMBL
  ENSRNOT00000120258.1 UniProtKB/TrEMBL
InterPro ECSCR UniProtKB/TrEMBL
KEGG Report rno:689248 UniProtKB/TrEMBL
NCBI Gene 689248 ENTREZGENE
PANTHER PTHR28602 UniProtKB/TrEMBL
Pfam ECSCR UniProtKB/TrEMBL
PhenoGen Ecscr PhenoGen
PRINTS ECCREGULATOR UniProtKB/TrEMBL
UniProt A0A8I6A6Y3_RAT UniProtKB/TrEMBL
  A0A8I6A8X7_RAT UniProtKB/TrEMBL
  A0A8I6G5C4_RAT UniProtKB/TrEMBL
  M0RCJ4 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-05-24 Ecscr  endothelial cell surface expressed chemotaxis and apoptosis regulator  LOC682650  hypothetical protein LOC682650  Data Merged 1643240 APPROVED
2013-03-06 Ecscr  endothelial cell surface expressed chemotaxis and apoptosis regulator  Ecscr  endothelial cell-specific chemotaxis regulator  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-03-05 Ecscr  endothelial cell-specific chemotaxis regulator  Ecscr-ps1  endothelial cell-specific chemotaxis regulator, pseudogene 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2011-06-08 Ecscr-ps1  endothelial cell-specific chemotaxis regulator, pseudogene 1  Ecscr  endothelial cell-specific chemotaxis regulator  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2010-04-23 Ecscr  endothelial cell-specific chemotaxis regulator  LOC689248  hypothetical protein LOC689248  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-11-20 LOC689248  hypothetical protein LOC689248      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-11-20 LOC682650  hypothetical protein LOC682650      Symbol and Name status set to provisional 70820 PROVISIONAL