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Gene: Lars1 (leucyl-tRNA synthetase 1) Rattus norvegicus
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Symbol: Lars1
Name: leucyl-tRNA synthetase 1
Description: Predicted to have GTPase activator activity; glutamine-tRNA ligase activity; and leucine-tRNA ligase activity. Predicted to be involved in several processes, including cellular response to leucine; cellular response to leucine starvation; and tRNA aminoacylation for protein translation. Predicted to localize to several cellular components, including the aminoacyl-tRNA synthetase multienzyme complex; lysosome; and nuclear body. Orthologous to human LARS1 (leucyl-tRNA synthetase 1); PARTICIPATES IN aminoacyl-tRNA biosynthetic pathway; valine, leucine and isoleucine biosynthetic pathway; INTERACTS WITH (+)-schisandrin B; 2,6-dinitrotoluene; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Lars; leucine--tRNA ligase, cytoplasmic; leucyl-tRNA synthetase; leucyl-tRNA synthetase, cytoplasmic; LOC291624; MGC105585
Orthologs:
Homo sapiens (human) : LARS1 (leucyl-tRNA synthetase 1)  HGNC  Alliance
Mus musculus (house mouse) : Lars (leucyl-tRNA synthetase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Lars1 (leucyl-tRNA synthetase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : LARS1 (leucyl-tRNA synthetase 1)
Canis lupus familiaris (dog) : LARS1 (leucyl-tRNA synthetase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lars1 (leucyl-tRNA synthetase 1)
Sus scrofa (pig) : LARS1 (leucyl-tRNA synthetase 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01836,524,013 - 36,579,471 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1836,524,007 - 36,579,403 (-)Ensembl
Rnor_5.01836,191,058 - 36,244,388 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41835,399,197 - 35,455,759 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11835,434,464 - 35,491,025 (-)NCBI
Celera1833,798,541 - 33,852,822 (-)NCBICelera
Cytogenetic Map18p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Lars1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1304962
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.