Ppp2r2b (protein phosphatase 2, regulatory subunit B, beta) - Rat Genome Database

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Gene: Ppp2r2b (protein phosphatase 2, regulatory subunit B, beta) Rattus norvegicus
Analyze
Symbol: Ppp2r2b
Name: protein phosphatase 2, regulatory subunit B, beta
RGD ID: 631441
Description: Predicted to have protein phosphatase regulator activity. Involved in several processes, including mitochondrion organization; nervous system development; and positive regulation of neuron apoptotic process. Localizes to cytosol; mitochondrial outer membrane; and protein phosphatase type 2A complex. Colocalizes with cytoskeleton. Human ortholog(s) of this gene implicated in Alzheimer's disease; brain disease; breast cancer; and spinocerebellar ataxia type 12. Orthologous to human PPP2R2B (protein phosphatase 2 regulatory subunit Bbeta); PARTICIPATES IN platelet-derived growth factor signaling pathway; Chagas disease pathway; hepatitis C pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,2',4,4',5,5'-hexachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: BRbeta B-regulatory subunit of protein phosphatase 2A; PP2A subunit B isoform B55-beta; PP2A subunit B isoform beta; PP2A subunit B isoform BRB; PP2A subunit B isoform PR55-beta; PP2A subunit B isoform R2-beta; PP2A, subunit B, B-beta isoform; PP2A, subunit B, B55-beta isoform; PP2A, subunit B, BRB isoform; PP2A, subunit B, PR55-beta isoform; PP2A, subunit B, R2-beta isoform; Pppr2b2; protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform; protein phosphatase 2 (formerly 2A), regulatory subunit B, beta isoform; serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: Ppp2r2bTn(sb-T2/Bart3)2.239Mcwi  
Genetic Models: F344-Ppp2r2bTn(sb-T2/Bart3)2.239Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21834,653,716 - 35,080,889 (-)NCBI
Rnor_6.0 Ensembl1836,985,714 - 37,245,809 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01836,985,709 - 37,421,383 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01836,647,298 - 37,076,455 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41835,865,837 - 36,318,308 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11835,901,503 - 36,179,323 (-)NCBI
Celera1834,248,471 - 34,670,726 (-)NCBICelera
Cytogenetic Map18p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,1-dichloroethene  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (EXP,ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,6-dinitrotoluene  (EXP)
2-nitrotoluene  (EXP)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (EXP)
7,12-dimethyltetraphene  (EXP)
aconitine  (EXP)
aflatoxin B1  (ISO)
aflatoxin B2  (ISO)
aflatoxin M1  (ISO)
all-trans-retinoic acid  (ISO)
alpha-hexachlorocyclohexane  (EXP)
ammonium chloride  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
atrazine  (EXP)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[e]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
bleomycin A5  (ISO)
bromochloroacetic acid  (EXP)
butanal  (ISO)
Butylbenzyl phthalate  (EXP)
caffeine  (ISO)
carbon nanotube  (ISO)
cisplatin  (ISO)
cocaine  (EXP)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
corticosterone  (EXP)
DDT  (EXP)
decabromodiphenyl ether  (EXP)
dibutyl phthalate  (EXP)
diethyl phthalate  (EXP)
diethylstilbestrol  (EXP)
diisobutyl phthalate  (EXP)
diisononyl phthalate  (EXP)
disulfiram  (ISO)
diuron  (EXP)
dorsomorphin  (ISO)
doxorubicin  (ISO)
ethanol  (ISO)
folic acid  (ISO)
gamma-hexachlorocyclohexane  (EXP)
genistein  (ISO)
GW 4064  (ISO)
Lasiocarpine  (ISO)
lead(0)  (ISO)
lead(2+)  (ISO)
LY294002  (ISO)
melphalan  (ISO)
mercury dibromide  (ISO)
methapyrilene  (ISO)
methylmercury chloride  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
nevirapine  (EXP)
niclosamide  (ISO)
Nor-9-carboxy-delta9-THC  (ISO)
O-methyleugenol  (ISO)
p-chloromercuribenzoic acid  (ISO)
panobinostat  (ISO)
PCB138  (ISO)
pentanal  (ISO)
phenylmercury acetate  (ISO)
pioglitazone  (ISO)
potassium chromate  (ISO)
pregnenolone 16alpha-carbonitrile  (EXP)
progesterone  (ISO)
rotenone  (EXP,ISO)
SB 431542  (ISO)
sodium arsenate  (ISO)
sodium fluoride  (EXP,ISO)
staurosporine  (EXP)
sulforaphane  (ISO)
triadimefon  (ISO)
trichostatin A  (ISO)
triphenyl phosphate  (EXP)
tunicamycin  (EXP)
valproic acid  (ISO)
vinclozolin  (EXP)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
1. Akiyama N, etal., Eur J Biochem 1995 Jun 1;230(2):766-72.
2. Brussino A, etal., Mov Disord. 2010 Jul 15;25(9):1269-73.
3. Crispin JC, etal., Proc Natl Acad Sci U S A. 2011 Jul 26;108(30):12443-8. Epub 2011 Jul 11.
4. Dagda RK, etal., J Biol Chem. 2003 Jul 4;278(27):24976-85. Epub 2003 Apr 24.
5. Dagda RK, etal., J Biol Chem. 2005 Jul 22;280(29):27375-82. Epub 2005 May 27.
6. Dagda RK, etal., J Biol Chem. 2008 Dec 26;283(52):36241-8. Epub 2008 Oct 21.
7. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
8. GOA data from the GO Consortium
9. Hatano Y, etal., FEBS Lett 1993 Jun 7;324(1):71-5.
10. Kimura R, etal., Neurosci Lett. 2011 Jan 10;487(3):354-7. Epub 2010 Oct 26.
11. OMIM Disease Annotation Pipeline
12. Pipeline to import KEGG annotations from KEGG into RGD
13. Pipeline to import Pathway Interaction Database annotations from NCI into RGD
14. RGD automated data pipeline
15. RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
16. RGD automated import pipeline for gene-chemical interactions
17. Strack S, etal., J Comp Neurol. 1998 Mar 23;392(4):515-27.
18. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
19. Vazquez A, etal., Int J Cancer. 2011 May 15;128(10):2335-43. doi: 10.1002/ijc.25582.
20. Wang YC, etal., J Biol Chem. 2011 Jun 17;286(24):21742-54. Epub 2011 Apr 6.
Additional References at PubMed
PMID:15489334   PMID:19029245  


Genomics

Comparative Map Data
Ppp2r2b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21834,653,716 - 35,080,889 (-)NCBI
Rnor_6.0 Ensembl1836,985,714 - 37,245,809 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01836,985,709 - 37,421,383 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01836,647,298 - 37,076,455 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41835,865,837 - 36,318,308 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11835,901,503 - 36,179,323 (-)NCBI
Celera1834,248,471 - 34,670,726 (-)NCBICelera
Cytogenetic Map18p11NCBI
PPP2R2B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl5146,581,146 - 147,084,784 (-)EnsemblGRCh38hg38GRCh38
GRCh38.p13 Ensembl5146,580,742 - 147,084,784 (-)EnsemblGRCh38hg38GRCh38
GRCh385146,580,742 - 147,081,520 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh375145,960,305 - 146,461,083 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 365145,949,260 - 146,441,207 (-)NCBINCBI36hg18NCBI36
Build 345145,949,261 - 146,441,207NCBI
Celera5142,050,506 - 142,543,249 (-)NCBI
Cytogenetic Map5q32NCBI
HuRef5141,115,900 - 141,608,335 (-)NCBIHuRef
CHM1_15145,401,722 - 145,893,553 (-)NCBICHM1_1
Ppp2r2b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391842,777,811 - 43,192,842 (-)NCBIGRCm39mm39
GRCm39 Ensembl1842,770,497 - 43,216,192 (-)Ensembl
GRCm381842,645,207 - 43,059,471 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1842,637,432 - 43,059,471 (-)EnsemblGRCm38mm10GRCm38
GRCm38.p6 Ensembl1842,637,432 - 43,083,127 (-)EnsemblGRCm38mm10GRCm38
MGSCv371842,804,923 - 43,219,125 (-)NCBIGRCm37mm9NCBIm37
MGSCv361842,771,242 - 43,184,802 (-)NCBImm8
Celera1844,014,172 - 44,430,759 (-)NCBICelera
Cytogenetic Map18B3NCBI
Ppp2r2b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554157,090,671 - 7,511,995 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554157,054,296 - 7,510,179 (+)NCBIChiLan1.0ChiLan1.0
PPP2R2B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.15148,050,581 - 148,533,583 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5148,050,581 - 148,533,329 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v05142,037,831 - 142,521,655 (-)NCBIMhudiblu_PPA_v0panPan3
PPP2R2B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1241,005,259 - 41,447,048 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl241,005,644 - 41,459,878 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha238,048,790 - 38,488,981 (-)NCBI
ROS_Cfam_1.0241,461,404 - 41,901,150 (-)NCBI
UMICH_Zoey_3.1238,535,055 - 38,978,764 (-)NCBI
UNSW_CanFamBas_1.0239,344,752 - 39,785,267 (-)NCBI
UU_Cfam_GSD_1.0240,170,245 - 40,610,151 (-)NCBI
Ppp2r2b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213146,081,945 - 146,522,525 (+)NCBI
SpeTri2.0NW_0049365047,655,924 - 8,097,125 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PPP2R2B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2147,937,439 - 148,411,731 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12147,938,074 - 148,422,825 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22154,429,929 - 154,517,148 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PPP2R2B
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12349,164,026 - 49,645,347 (-)NCBI
Vero_WHO_p1.0NW_02366603428,133,756 - 28,621,365 (+)NCBI
Ppp2r2b
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247746,081,818 - 6,539,226 (-)NCBI

Position Markers
D18Rat139  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21834,710,216 - 34,710,448 (+)MAPPER
Rnor_6.01837,042,221 - 37,042,452NCBIRnor6.0
Rnor_5.01836,703,395 - 36,703,626UniSTSRnor5.0
RGSC_v3.41835,922,193 - 35,922,425RGDRGSC3.4
RGSC_v3.41835,922,194 - 35,922,425UniSTSRGSC3.4
RGSC_v3.11835,957,459 - 35,957,691RGD
Celera1834,304,851 - 34,305,082UniSTS
SHRSP x BN Map1817.1699RGD
SHRSP x BN Map1817.1699UniSTS
Cytogenetic Map18p11UniSTS
D18Got80  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21834,891,756 - 34,891,899 (+)MAPPER
Rnor_6.01837,224,298 - 37,224,440NCBIRnor6.0
Rnor_5.01836,884,885 - 36,885,027UniSTSRnor5.0
RGSC_v3.41836,122,754 - 36,122,897RGDRGSC3.4
RGSC_v3.41836,122,755 - 36,122,897UniSTSRGSC3.4
RGSC_v3.11836,158,020 - 36,158,163RGD
Celera1834,482,873 - 34,483,015UniSTS
Cytogenetic Map18p11UniSTS
D18Chm46  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21835,035,986 - 35,036,216 (+)MAPPER
Rnor_6.01837,375,987 - 37,376,216NCBIRnor6.0
Rnor_5.01837,031,940 - 37,032,169UniSTSRnor5.0
RGSC_v3.41836,268,700 - 36,268,929UniSTSRGSC3.4
Cytogenetic Map18p11UniSTS
D18Got126  
Rat AssemblyChrPosition (strand)SourceJBrowse
Celera1834,523,700 - 34,523,883UniSTS
Cytogenetic Map18p11UniSTS
RH127928  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21834,653,895 - 34,654,084 (+)MAPPER
Rnor_6.01836,985,889 - 36,986,077NCBIRnor6.0
Rnor_5.01836,647,478 - 36,647,666UniSTSRnor5.0
RGSC_v3.41835,865,968 - 35,866,156UniSTSRGSC3.4
Celera1834,248,651 - 34,248,839UniSTS
Cytogenetic Map18p11UniSTS
AU047127  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21834,669,428 - 34,669,580 (+)MAPPER
Rnor_6.01837,001,422 - 37,001,573NCBIRnor6.0
Rnor_5.01836,663,011 - 36,663,162UniSTSRnor5.0
RGSC_v3.41835,881,501 - 35,881,652UniSTSRGSC3.4
Celera1834,264,184 - 34,264,335UniSTS
Cytogenetic Map18p11UniSTS
AU048553  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21834,805,553 - 34,805,821 (+)MAPPER
Rnor_6.01837,137,923 - 37,138,190NCBIRnor6.0
Rnor_5.01836,798,929 - 36,799,196UniSTSRnor5.0
RGSC_v3.41836,018,045 - 36,018,312UniSTSRGSC3.4
Celera1834,396,765 - 34,397,032UniSTS
Cytogenetic Map18p11UniSTS
AU048718  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21834,977,075 - 34,977,264 (+)MAPPER
Rnor_6.01837,315,939 - 37,316,127NCBIRnor6.0
Rnor_5.01836,973,415 - 36,973,603UniSTSRnor5.0
RGSC_v3.41836,209,474 - 36,209,662UniSTSRGSC3.4
Celera1834,567,235 - 34,567,423UniSTS
Cytogenetic Map18p11UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2300180Bmd67Bone mineral density QTL 674.80.0001femur mineral mass (VT:0010011)bone mineral density (CMO:0001226)18138195967Rat
2293661Bss50Bone structure and strength QTL 504.640.0003lumbar vertebra size trait (VT:0010518)lumbar vertebra trabecular cross-sectional area (CMO:0001692)18138195967Rat
9589153Insul31Insulin level QTL 317.150.05blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)18138753381Rat
2299160Iddm35Insulin dependent diabetes mellitus QTL 352.79blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)18440751362570466Rat
2312568Glom21Glomerulus QTL 2120.005kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)18543013441781619Rat
2313082Bss85Bone structure and strength QTL 850.80.0001long bone metaphysis morphology trait (VT:0000133)tibia midshaft total cross-sectional area (CMO:0001715)181467885259678852Rat
1331753Bp231Blood pressure QTL 2313.643arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)181553942753861431Rat
1358358Sradr6Stress Responsive Adrenal Weight QTL 62.49adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)181553942761499684Rat
6903359Bp355Blood pressure QTL 3553.6arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)181553967161985648Rat
2293708Bss46Bone structure and strength QTL 468.80.0001lumbar vertebra morphology trait (VT:0010494)lumbar vertebra cortical cross-sectional area (CMO:0001690)181569587268524999Rat
1578661Bss20Bone structure and strength QTL 203.7femur morphology trait (VT:0000559)femoral neck cross-sectional area (CMO:0001697)181569587287080053Rat
1578667Bss21Bone structure and strength QTL 213.5femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)181569587287080053Rat
1358193Emca2Estrogen-induced mammary cancer QTL 21.6mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)181903103068436105Rat
1600373Mamtr6Mammary tumor resistance QTL 6mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)182028575887080053Rat
7387267Uae42Urinary albumin excretion QTL 420.61urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)142163949166639491Rat
1331741Bp232Blood pressure QTL 2323.59112arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)182260373687074531Rat
6903353Bp353Blood pressure QTL 3532.8arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)182260476461985648Rat
1641923Colcr8Colorectal carcinoma resistance QTL 83.10.0014intestine integrity trait (VT:0010554)poorly differentiated malignant colorectal tumor number (CMO:0002076)182318422753861431Rat
1331733Bp233Blood pressure QTL 2333.97196arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)182596102681761656Rat
2325839Bp348Blood pressure QTL 3480.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)182674340443659626Rat
2301413Bp318Blood pressure QTL 3180.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)182774302448499517Rat
12904673Cm127Cardiac mass QTL 1270.005heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)182774302448499517Rat
12904675Am19Aortic mass QTL 190.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)182774302448499517Rat
12904677Kidm72Kidney mass QTL 720.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)182774302448499517Rat
12904668Bw188Body weight QTL 1880.03body mass (VT:0001259)body weight (CMO:0000012)182774302448499517Rat
12904669Cm125Cardiac mass QTL 1250.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)182774302448499517Rat
12904670Cm126Cardiac mass QTL 1260.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)182774302448499517Rat
2300157Bmd66Bone mineral density QTL 6613.10.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)183053361475533614Rat
2300177Bmd65Bone mineral density QTL 6519.70.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)183053361475533614Rat
2293704Bss35Bone structure and strength QTL 354.590.0002femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)183053361475533614Rat
9590318Scort22Serum corticosterone level QTL 227.640.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)183136134176361341Rat
1331754Bp230Blood pressure QTL 2304.61609arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183136134176361341Rat
9589816Gluco68Glucose level QTL 687.250.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)183136134176361341Rat
8694378Bw157Body weight QTL 1573.590.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)183136134176361341Rat
738005Anxrr11Anxiety related response QTL 113.4exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)183160842476608424Rat
61383Bp47Blood pressure QTL 4717.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)183172837362570429Rat
1331776Bp225Blood pressure QTL 2252.829arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)183267035261985812Rat
1331774Bp226Blood pressure QTL 2264.41065arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183267035261985812Rat
1331742Bp228Blood pressure QTL 2283.88752arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183267035261985812Rat
1331798Bp224Blood pressure QTL 2243.53873arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183267035261985812Rat
1331727Bp237Blood pressure QTL 2373.053arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183267035263897621Rat
61429Cia17Collagen induced arthritis QTL 174.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)183267035273016546Rat
2303120Mamtr8Mammary tumor resistance QTL 80.001mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)183267035287080053Rat
6903347Bp350Blood pressure QTL 3504.4arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183267047361985648Rat
631274Sprol1Serum protein level QTL 15.3blood total protein amount (VT:0005567)serum total protein level (CMO:0000661)183270402280696226Rat


Genetic Models
This gene Ppp2r2b is modified in the following models/strains
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:479
Count of miRNA genes:253
Interacting mature miRNAs:299
Transcripts:ENSRNOT00000041188
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 4 4 4 68 2 26
Low 3 42 48 37 6 37 7 9 6 33 15 10 7
Below cutoff 1 5 13 1 2 1 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_022209 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_073588 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017601025 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017601026 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017601027 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017601028 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017601029 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039097058 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039097059 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039097060 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039097061 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039097062 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039097063 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039097064 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039097065 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039097066 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039097067 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039097068 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039097069 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039097070 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039097071 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039097072 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039097073 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AY251277 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC078834 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB692853 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473974 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D14421 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D38260 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DV721136 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FM080850 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ212581 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000299 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000041188   ⟹   ENSRNOP00000041264
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1836,985,714 - 37,096,132 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000079585   ⟹   ENSRNOP00000071824
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1836,986,162 - 37,245,809 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000091634   ⟹   ENSRNOP00000071716
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1836,986,095 - 37,132,223 (-)Ensembl
RefSeq Acc Id: NM_022209   ⟹   NP_071545
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21834,653,716 - 35,080,666 (-)NCBI
Rnor_6.01836,985,709 - 37,421,383 (-)NCBI
Rnor_5.01836,647,298 - 37,076,455 (-)NCBI
RGSC_v3.41835,865,837 - 36,318,308 (-)RGD
Celera1834,248,471 - 34,670,726 (-)NCBI
Sequence:
RefSeq Acc Id: NR_073588
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21834,653,716 - 34,952,055 (-)NCBI
Rnor_6.01836,985,709 - 37,291,494 (-)NCBI
Rnor_5.01836,647,298 - 37,076,455 (-)NCBI
Celera1834,248,471 - 34,542,212 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017601025   ⟹   XP_017456514
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01836,985,712 - 37,246,723 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017601026   ⟹   XP_017456515
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21834,653,716 - 34,823,414 (-)NCBI
Rnor_6.01836,985,712 - 37,155,807 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017601027   ⟹   XP_017456516
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01836,985,712 - 37,155,530 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017601028   ⟹   XP_017456517
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21834,653,716 - 34,952,102 (-)NCBI
Rnor_6.01836,985,712 - 37,291,538 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017601029   ⟹   XP_017456518
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21834,653,716 - 34,952,102 (-)NCBI
Rnor_6.01836,985,712 - 37,291,537 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039097058   ⟹   XP_038952986
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21834,653,716 - 35,080,889 (-)NCBI
RefSeq Acc Id: XM_039097059   ⟹   XP_038952987
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21834,653,716 - 34,914,070 (-)NCBI
RefSeq Acc Id: XM_039097060   ⟹   XP_038952988
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21834,653,716 - 34,952,104 (-)NCBI
RefSeq Acc Id: XM_039097061   ⟹   XP_038952989
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21834,653,716 - 34,942,316 (-)NCBI
RefSeq Acc Id: XM_039097062   ⟹   XP_038952990
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21834,653,716 - 34,799,791 (-)NCBI
RefSeq Acc Id: XM_039097063   ⟹   XP_038952991
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21834,653,716 - 34,857,103 (-)NCBI
RefSeq Acc Id: XM_039097064   ⟹   XP_038952992
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21834,653,716 - 34,823,421 (-)NCBI
RefSeq Acc Id: XM_039097065   ⟹   XP_038952993
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21834,653,716 - 34,952,104 (-)NCBI
RefSeq Acc Id: XM_039097066   ⟹   XP_038952994
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21834,653,716 - 34,952,104 (-)NCBI
RefSeq Acc Id: XM_039097067   ⟹   XP_038952995
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21834,653,716 - 34,952,104 (-)NCBI
RefSeq Acc Id: XM_039097068   ⟹   XP_038952996
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21834,653,716 - 34,952,104 (-)NCBI
RefSeq Acc Id: XM_039097069   ⟹   XP_038952997
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21834,653,716 - 34,833,872 (-)NCBI
RefSeq Acc Id: XM_039097070   ⟹   XP_038952998
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21834,653,716 - 34,914,068 (-)NCBI
RefSeq Acc Id: XM_039097071   ⟹   XP_038952999
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21834,653,716 - 34,857,099 (-)NCBI
RefSeq Acc Id: XM_039097072   ⟹   XP_038953000
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21834,653,716 - 34,952,098 (-)NCBI
RefSeq Acc Id: XM_039097073   ⟹   XP_038953001
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21834,653,716 - 34,952,098 (-)NCBI
Protein Sequences
Protein RefSeqs NP_071545 (Get FASTA)   NCBI Sequence Viewer  
  XP_017456515 (Get FASTA)   NCBI Sequence Viewer  
  XP_017456517 (Get FASTA)   NCBI Sequence Viewer  
  XP_017456518 (Get FASTA)   NCBI Sequence Viewer  
  XP_038952986 (Get FASTA)   NCBI Sequence Viewer  
  XP_038952987 (Get FASTA)   NCBI Sequence Viewer  
  XP_038952988 (Get FASTA)   NCBI Sequence Viewer  
  XP_038952989 (Get FASTA)   NCBI Sequence Viewer  
  XP_038952990 (Get FASTA)   NCBI Sequence Viewer  
  XP_038952991 (Get FASTA)   NCBI Sequence Viewer  
  XP_038952992 (Get FASTA)   NCBI Sequence Viewer  
  XP_038952993 (Get FASTA)   NCBI Sequence Viewer  
  XP_038952994 (Get FASTA)   NCBI Sequence Viewer  
  XP_038952995 (Get FASTA)   NCBI Sequence Viewer  
  XP_038952996 (Get FASTA)   NCBI Sequence Viewer  
  XP_038952997 (Get FASTA)   NCBI Sequence Viewer  
  XP_038952998 (Get FASTA)   NCBI Sequence Viewer  
  XP_038952999 (Get FASTA)   NCBI Sequence Viewer  
  XP_038953000 (Get FASTA)   NCBI Sequence Viewer  
  XP_038953001 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH78834 (Get FASTA)   NCBI Sequence Viewer  
  AAP33142 (Get FASTA)   NCBI Sequence Viewer  
  BAA03313 (Get FASTA)   NCBI Sequence Viewer  
  BAA07412 (Get FASTA)   NCBI Sequence Viewer  
  EDL76491 (Get FASTA)   NCBI Sequence Viewer  
  EDL76492 (Get FASTA)   NCBI Sequence Viewer  
  EDL76493 (Get FASTA)   NCBI Sequence Viewer  
  EDL76494 (Get FASTA)   NCBI Sequence Viewer  
  P36877 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_071545   ⟸   NM_022209
- UniProtKB: P36877 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_017456517   ⟸   XM_017601028
- Peptide Label: isoform X11
- Sequence:
RefSeq Acc Id: XP_017456518   ⟸   XM_017601029
- Peptide Label: isoform X12
- Sequence:
RefSeq Acc Id: XP_017456514   ⟸   XM_017601025
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_017456515   ⟸   XM_017601026
- Peptide Label: isoform X10
- Sequence:
RefSeq Acc Id: XP_017456516   ⟸   XM_017601027
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSRNOP00000041264   ⟸   ENSRNOT00000041188
RefSeq Acc Id: ENSRNOP00000071824   ⟸   ENSRNOT00000079585
RefSeq Acc Id: ENSRNOP00000071716   ⟸   ENSRNOT00000091634
RefSeq Acc Id: XP_038952986   ⟸   XM_039097058
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038952996   ⟸   XM_039097068
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038952993   ⟸   XM_039097065
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038952988   ⟸   XM_039097060
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038952994   ⟸   XM_039097066
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038952995   ⟸   XM_039097067
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038953001   ⟸   XM_039097073
- Peptide Label: isoform X13
RefSeq Acc Id: XP_038953000   ⟸   XM_039097072
- Peptide Label: isoform X13
RefSeq Acc Id: XP_038952989   ⟸   XM_039097061
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038952987   ⟸   XM_039097059
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038952998   ⟸   XM_039097070
- Peptide Label: isoform X8
RefSeq Acc Id: XP_038952991   ⟸   XM_039097063
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038952999   ⟸   XM_039097071
- Peptide Label: isoform X9
RefSeq Acc Id: XP_038952997   ⟸   XM_039097069
- Peptide Label: isoform X7
RefSeq Acc Id: XP_038952992   ⟸   XM_039097064
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038952990   ⟸   XM_039097062
- Peptide Label: isoform X3

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:631441 AgrOrtholog
Ensembl Genes ENSRNOG00000018851 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000041264 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOP00000071716 UniProtKB/TrEMBL
  ENSRNOP00000071824 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000041188 UniProtKB/TrEMBL
  ENSRNOT00000079585 UniProtKB/Swiss-Prot
  ENSRNOT00000091634 UniProtKB/TrEMBL
Gene3D-CATH 2.130.10.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7114294 IMAGE-MGC_LOAD
InterPro PP2A_PR55 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PP2A_PR55_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD40/YVTN_repeat-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD40_repeat UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD40_repeat_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD40_repeat_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:60660 UniProtKB/Swiss-Prot
MGC_CLONE MGC:93454 IMAGE-MGC_LOAD
NCBI Gene 60660 ENTREZGENE
PANTHER PTHR11871 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Ppp2r2b PhenoGen
PIRSF PP2A_PR55 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS PP2APR55 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE PR55_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PR55_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD_REPEATS_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART WD40 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF50978 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt 2ABB_RAT UniProtKB/Swiss-Prot
  A0A0G2K165_RAT UniProtKB/TrEMBL
  P36877 ENTREZGENE
  Z4YNW7_RAT UniProtKB/TrEMBL
UniProt Secondary Q80W84 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2004-09-10 Ppp2r2b  protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform  Pppr2b2    Symbol updated 1299863 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_expression expressed in brain and testis 633587