Ppp2r2b (protein phosphatase 2, regulatory subunit B, beta) - Rat Genome Database

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Gene: Ppp2r2b (protein phosphatase 2, regulatory subunit B, beta) Rattus norvegicus
Analyze
Symbol: Ppp2r2b
Name: protein phosphatase 2, regulatory subunit B, beta
RGD ID: 631441
Description: Predicted to enable protein phosphatase regulator activity. Involved in several processes, including mitochondrion organization; positive regulation of neuron apoptotic process; and protein targeting to mitochondrion. Located in mitochondrial outer membrane. Part of protein phosphatase type 2A complex. Human ortholog(s) of this gene implicated in Alzheimer's disease; brain disease; breast cancer; and spinocerebellar ataxia type 12. Orthologous to human PPP2R2B (protein phosphatase 2 regulatory subunit Bbeta); PARTICIPATES IN platelet-derived growth factor signaling pathway; Chagas disease pathway; hepatitis C pathway; INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,2',4,4',5,5'-hexachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: BRbeta B-regulatory subunit of protein phosphatase 2A; PP2A subunit B isoform B55-beta; PP2A subunit B isoform beta; PP2A subunit B isoform BRB; PP2A subunit B isoform PR55-beta; PP2A subunit B isoform R2-beta; PP2A, subunit B, B-beta isoform; PP2A, subunit B, B55-beta isoform; PP2A, subunit B, BRB isoform; PP2A, subunit B, PR55-beta isoform; PP2A, subunit B, R2-beta isoform; Pppr2b2; protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform; protein phosphatase 2 (formerly 2A), regulatory subunit B, beta isoform; serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: Ppp2r2bTn(sb-T2/Bart3)2.239Mcwi  
Genetic Models: F344-Ppp2r2bTn(sb-T2/Bart3)2.239Mcwi
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81834,904,686 - 35,357,299 (-)NCBIGRCr8
mRatBN7.21834,653,716 - 35,080,889 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1834,653,721 - 35,081,025 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1834,757,854 - 35,184,717 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01835,476,177 - 35,903,042 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01834,853,095 - 35,279,989 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01836,985,709 - 37,421,383 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1836,985,714 - 37,245,809 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01836,647,298 - 37,076,455 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41835,865,837 - 36,318,308 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11835,901,503 - 36,179,323 (-)NCBI
Celera1834,248,471 - 34,670,726 (-)NCBICelera
Cytogenetic Map18p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,1-dichloroethene  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (EXP,ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (EXP,ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,6-dinitrotoluene  (EXP)
2-nitrotoluene  (EXP)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
4,4'-sulfonyldiphenol  (EXP)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (EXP)
7,12-dimethyltetraphene  (EXP)
aconitine  (EXP)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
aflatoxin M1  (ISO)
all-trans-retinoic acid  (ISO)
alpha-hexachlorocyclohexane  (EXP)
ammonium chloride  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
atrazine  (EXP)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[e]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP,ISO)
bleomycin A5  (ISO)
bromochloroacetic acid  (EXP)
butanal  (ISO)
Butylbenzyl phthalate  (EXP)
caffeine  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chromium(6+)  (ISO)
cisplatin  (ISO)
cocaine  (EXP)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
corticosterone  (EXP)
DDT  (EXP)
decabromodiphenyl ether  (EXP)
dibutyl phthalate  (EXP)
diethyl phthalate  (EXP)
diethylstilbestrol  (EXP)
diisobutyl phthalate  (EXP)
diisononyl phthalate  (EXP)
disulfiram  (ISO)
diuron  (EXP)
dorsomorphin  (ISO)
doxorubicin  (ISO)
ethanol  (ISO)
folic acid  (ISO)
fulvestrant  (ISO)
gamma-hexachlorocyclohexane  (EXP)
genistein  (ISO)
gentamycin  (EXP)
GW 4064  (ISO)
inulin  (ISO)
ketoconazole  (EXP)
Lasiocarpine  (ISO)
lead(0)  (ISO)
LY294002  (ISO)
melphalan  (ISO)
mercury dibromide  (ISO)
methapyrilene  (ISO)
methoxychlor  (EXP)
methylmercury chloride  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
nevirapine  (EXP)
niclosamide  (ISO)
Nor-9-carboxy-delta9-THC  (ISO)
O-methyleugenol  (ISO)
p-chloromercuribenzoic acid  (ISO)
panobinostat  (ISO)
PCB138  (ISO)
pentanal  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenylmercury acetate  (ISO)
pioglitazone  (ISO)
potassium chromate  (ISO)
pregnenolone 16alpha-carbonitrile  (EXP)
progesterone  (ISO)
rotenone  (EXP,ISO)
SB 431542  (ISO)
sodium arsenate  (ISO)
sodium fluoride  (EXP,ISO)
staurosporine  (EXP)
sulforaphane  (ISO)
temozolomide  (ISO)
triadimefon  (ISO)
trichostatin A  (ISO)
triphenyl phosphate  (EXP,ISO)
tunicamycin  (EXP)
valproic acid  (ISO)
vinclozolin  (EXP)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. cDNA cloning of BR gamma, a novel brain-specific isoform of the B regulatory subunit of type-2A protein phosphatase. Akiyama N, etal., Eur J Biochem 1995 Jun 1;230(2):766-72.
2. Spinocerebellar ataxia type 12 identified in two Italian families may mimic sporadic ataxia. Brussino A, etal., Mov Disord. 2010 Jul 15;25(9):1269-73.
3. Induction of PP2A Bbeta, a regulator of IL-2 deprivation-induced T-cell apoptosis, is deficient in systemic lupus erythematosus. Crispin JC, etal., Proc Natl Acad Sci U S A. 2011 Jul 26;108(30):12443-8. Epub 2011 Jul 11.
4. A developmentally regulated, neuron-specific splice variant of the variable subunit Bbeta targets protein phosphatase 2A to mitochondria and modulates apoptosis. Dagda RK, etal., J Biol Chem. 2003 Jul 4;278(27):24976-85. Epub 2003 Apr 24.
5. Unfolding-resistant translocase targeting: a novel mechanism for outer mitochondrial membrane localization exemplified by the Bbeta2 regulatory subunit of protein phosphatase 2A. Dagda RK, etal., J Biol Chem. 2005 Jul 22;280(29):27375-82. Epub 2005 May 27.
6. The spinocerebellar ataxia 12 gene product and protein phosphatase 2A regulatory subunit Bbeta2 antagonizes neuronal survival by promoting mitochondrial fission. Dagda RK, etal., J Biol Chem. 2008 Dec 26;283(52):36241-8. Epub 2008 Oct 21.
7. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
8. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
9. Expression of PP2A B regulatory subunit beta isotype in rat testis. Hatano Y, etal., FEBS Lett 1993 Jun 7;324(1):71-5.
10. Association between CAG repeat length in the PPP2R2B gene and Alzheimer disease in the Japanese population. Kimura R, etal., Neurosci Lett. 2011 Jan 10;487(3):354-7. Epub 2010 Oct 26.
11. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
12. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
13. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
14. GOA pipeline RGD automated data pipeline
15. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
16. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
17. Brain protein phosphatase 2A: developmental regulation and distinct cellular and subcellular localization by B subunits. Strack S, etal., J Comp Neurol. 1998 Mar 23;392(4):515-27.
18. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
19. A genetic variant in a PP2A regulatory subunit encoded by the PPP2R2B gene associates with altered breast cancer risk and recurrence. Vazquez A, etal., Int J Cancer. 2011 May 15;128(10):2335-43. doi: 10.1002/ijc.25582.
20. Mitochondrial dysfunction and oxidative stress contribute to the pathogenesis of spinocerebellar ataxia type 12 (SCA12). Wang YC, etal., J Biol Chem. 2011 Jun 17;286(24):21742-54. Epub 2011 Apr 6.
Additional References at PubMed
PMID:15489334   PMID:19029245  


Genomics

Comparative Map Data
Ppp2r2b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81834,904,686 - 35,357,299 (-)NCBIGRCr8
mRatBN7.21834,653,716 - 35,080,889 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1834,653,721 - 35,081,025 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1834,757,854 - 35,184,717 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01835,476,177 - 35,903,042 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01834,853,095 - 35,279,989 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01836,985,709 - 37,421,383 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1836,985,714 - 37,245,809 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01836,647,298 - 37,076,455 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41835,865,837 - 36,318,308 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11835,901,503 - 36,179,323 (-)NCBI
Celera1834,248,471 - 34,670,726 (-)NCBICelera
Cytogenetic Map18p11NCBI
PPP2R2B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385146,580,742 - 147,081,520 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5146,580,742 - 147,084,784 (-)EnsemblGRCh38hg38GRCh38
GRCh375145,960,305 - 146,461,083 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 365145,949,260 - 146,441,207 (-)NCBINCBI36Build 36hg18NCBI36
Build 345145,949,261 - 146,441,207NCBI
Celera5142,050,506 - 142,543,249 (-)NCBICelera
Cytogenetic Map5q32NCBI
HuRef5141,115,900 - 141,608,335 (-)NCBIHuRef
CHM1_15145,401,722 - 145,893,553 (-)NCBICHM1_1
T2T-CHM13v2.05147,116,637 - 147,617,597 (-)NCBIT2T-CHM13v2.0
Ppp2r2b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391842,777,811 - 43,192,827 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1842,770,497 - 43,216,192 (-)EnsemblGRCm39 Ensembl
GRCm381842,645,207 - 43,059,471 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1842,637,432 - 43,059,471 (-)EnsemblGRCm38mm10GRCm38
GRCm38.p6 Ensembl1842,637,432 - 43,083,127 (-)EnsemblGRCm38mm10GRCm38
MGSCv371842,804,923 - 43,219,125 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361842,771,242 - 43,184,802 (-)NCBIMGSCv36mm8
Celera1844,014,172 - 44,430,759 (-)NCBICelera
Cytogenetic Map18B3NCBI
cM Map1822.75NCBI
Ppp2r2b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554157,090,671 - 7,511,995 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554157,054,296 - 7,510,179 (+)NCBIChiLan1.0ChiLan1.0
PPP2R2B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24141,841,949 - 142,325,863 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15139,981,500 - 140,465,413 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05142,037,831 - 142,521,655 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15148,050,581 - 148,533,583 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5148,050,581 - 148,533,329 (-)Ensemblpanpan1.1panPan2
PPP2R2B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1241,005,259 - 41,447,048 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl241,005,644 - 41,459,878 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha238,048,790 - 38,488,981 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0241,461,404 - 41,901,150 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl241,461,411 - 41,901,167 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1238,535,055 - 38,978,764 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0239,344,752 - 39,785,267 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0240,170,245 - 40,610,151 (-)NCBIUU_Cfam_GSD_1.0
Ppp2r2b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213146,081,945 - 146,522,525 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365047,656,298 - 8,097,276 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365047,655,924 - 8,097,125 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PPP2R2B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2147,937,442 - 148,411,731 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12147,938,074 - 148,422,825 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22154,429,929 - 154,517,148 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PPP2R2B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12349,164,026 - 49,645,347 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603428,133,756 - 28,621,365 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ppp2r2b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247746,078,905 - 6,539,289 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247746,081,818 - 6,539,226 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Ppp2r2b
1417 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:479
Count of miRNA genes:253
Interacting mature miRNAs:299
Transcripts:ENSRNOT00000041188
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331733Bp233Blood pressure QTL 2333.97196arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)182479697779788953Rat
1358358Sradr6Stress Responsive Adrenal Weight QTL 62.49adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)181194429959330563Rat
1331798Bp224Blood pressure QTL 2243.53873arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183135940859796643Rat
2301413Bp318Blood pressure QTL 3180.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)182654808246969551Rat
61383Bp47Blood pressure QTL 4717.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)183127168160377755Rat
1331741Bp232Blood pressure QTL 2323.59112arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)182137289383213037Rat
1331742Bp228Blood pressure QTL 2283.88752arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183135940859796643Rat
61388Bp2Blood pressure QTL 23.23arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)18135374722Rat
1331776Bp225Blood pressure QTL 2252.829arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)183135940859796643Rat
6903359Bp355Blood pressure QTL 3553.6arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)181194454459796478Rat
12904668Bw188Body weight QTL 1880.03body mass (VT:0001259)body weight (CMO:0000012)182654808246969551Rat
2313082Bss85Bone structure and strength QTL 850.80.0001long bone metaphysis morphology trait (VT:0000133)tibia midshaft total cross-sectional area (CMO:0001715)181495133759951337Rat
12904669Cm125Cardiac mass QTL 1250.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)182654808246969551Rat
1641923Colcr8Colorectal carcinoma resistance QTL 83.10.0014intestine integrity trait (VT:0010554)poorly differentiated malignant colorectal tumor number (CMO:0002076)182206624252293055Rat
12904670Cm126Cardiac mass QTL 1260.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)182654808246969551Rat
6903347Bp350Blood pressure QTL 3504.4arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183135953059796478Rat
2312568Glom21Glomerulus QTL 2120.005kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)18518585840503530Rat
1331727Bp237Blood pressure QTL 2373.053arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183135940861698465Rat
2300157Bmd66Bone mineral density QTL 6613.10.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)182896485373964853Rat
738005Anxrr11Anxiety related response QTL 113.4exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)183003981375039813Rat
12904677Kidm72Kidney mass QTL 720.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)182654808246969551Rat
631274Sprol1Serum protein level QTL 15.3blood total protein amount (VT:0005567)serum total protein level (CMO:0000661)183139332077209694Rat
1358193Emca2Estrogen-induced mammary cancer QTL 21.6mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)181800759963571040Rat
12904673Cm127Cardiac mass QTL 1270.005heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)182654808246969551Rat
12904675Am19Aortic mass QTL 190.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)182654808246969551Rat
2293704Bss35Bone structure and strength QTL 354.590.0002femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)182896485373964853Rat
9589816Gluco68Glucose level QTL 687.250.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)182979296574792965Rat
1331774Bp226Blood pressure QTL 2264.41065arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183135940859796643Rat
2325839Bp348Blood pressure QTL 3480.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)182557098570570985Rat
1600373Mamtr6Mammary tumor resistance QTL 6mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)181927890183218561Rat
2293708Bss46Bone structure and strength QTL 468.80.0001lumbar vertebra morphology trait (VT:0010494)lumbar vertebra cortical cross-sectional area (CMO:0001690)181179151863636873Rat
8694378Bw157Body weight QTL 1573.590.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)182979296574792965Rat
2300177Bmd65Bone mineral density QTL 6519.70.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)182896485373964853Rat
9589153Insul31Insulin level QTL 317.150.05blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)18142547119Rat
1578667Bss21Bone structure and strength QTL 213.5femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)181179151883218561Rat
2303120Mamtr8Mammary tumor resistance QTL 80.001mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)183135940883218561Rat
61429Cia17Collagen induced arthritis QTL 174.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)183135940870263868Rat
2299160Iddm35Insulin dependent diabetes mellitus QTL 352.79blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)18420794160377792Rat
9590318Scort22Serum corticosterone level QTL 227.640.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)182979296574792965Rat
1578661Bss20Bone structure and strength QTL 203.7femur morphology trait (VT:0000559)femoral neck cross-sectional area (CMO:0001697)181179151883218561Rat
1331753Bp231Blood pressure QTL 2313.643arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)181194429952293055Rat
1331754Bp230Blood pressure QTL 2304.61609arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)182979296574792965Rat
61375Bp41Blood pressure QTL 412.4blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)181194429941122201Rat

Markers in Region
D18Rat139  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21834,710,216 - 34,710,448 (+)MAPPERmRatBN7.2
Rnor_6.01837,042,221 - 37,042,452NCBIRnor6.0
Rnor_5.01836,703,395 - 36,703,626UniSTSRnor5.0
RGSC_v3.41835,922,193 - 35,922,425RGDRGSC3.4
RGSC_v3.41835,922,194 - 35,922,425UniSTSRGSC3.4
RGSC_v3.11835,957,459 - 35,957,691RGD
Celera1834,304,851 - 34,305,082UniSTS
SHRSP x BN Map1817.1699RGD
SHRSP x BN Map1817.1699UniSTS
Cytogenetic Map18p11UniSTS
D18Got80  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21834,891,756 - 34,891,899 (+)MAPPERmRatBN7.2
Rnor_6.01837,224,298 - 37,224,440NCBIRnor6.0
Rnor_5.01836,884,885 - 36,885,027UniSTSRnor5.0
RGSC_v3.41836,122,754 - 36,122,897RGDRGSC3.4
RGSC_v3.41836,122,755 - 36,122,897UniSTSRGSC3.4
RGSC_v3.11836,158,020 - 36,158,163RGD
Celera1834,482,873 - 34,483,015UniSTS
Cytogenetic Map18p11UniSTS
D18Chm46  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21835,035,986 - 35,036,216 (+)MAPPERmRatBN7.2
Rnor_6.01837,375,987 - 37,376,216NCBIRnor6.0
Rnor_5.01837,031,940 - 37,032,169UniSTSRnor5.0
RGSC_v3.41836,268,700 - 36,268,929UniSTSRGSC3.4
Cytogenetic Map18p11UniSTS
D18Got126  
Rat AssemblyChrPosition (strand)SourceJBrowse
Celera1834,523,700 - 34,523,883UniSTS
Cytogenetic Map18p11UniSTS
RH127928  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21834,653,895 - 34,654,084 (+)MAPPERmRatBN7.2
Rnor_6.01836,985,889 - 36,986,077NCBIRnor6.0
Rnor_5.01836,647,478 - 36,647,666UniSTSRnor5.0
RGSC_v3.41835,865,968 - 35,866,156UniSTSRGSC3.4
Celera1834,248,651 - 34,248,839UniSTS
Cytogenetic Map18p11UniSTS
AU047127  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21834,669,428 - 34,669,580 (+)MAPPERmRatBN7.2
Rnor_6.01837,001,422 - 37,001,573NCBIRnor6.0
Rnor_5.01836,663,011 - 36,663,162UniSTSRnor5.0
RGSC_v3.41835,881,501 - 35,881,652UniSTSRGSC3.4
Celera1834,264,184 - 34,264,335UniSTS
Cytogenetic Map18p11UniSTS
AU048553  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21834,805,553 - 34,805,821 (+)MAPPERmRatBN7.2
Rnor_6.01837,137,923 - 37,138,190NCBIRnor6.0
Rnor_5.01836,798,929 - 36,799,196UniSTSRnor5.0
RGSC_v3.41836,018,045 - 36,018,312UniSTSRGSC3.4
Celera1834,396,765 - 34,397,032UniSTS
Cytogenetic Map18p11UniSTS
AU048718  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21834,977,075 - 34,977,264 (+)MAPPERmRatBN7.2
Rnor_6.01837,315,939 - 37,316,127NCBIRnor6.0
Rnor_5.01836,973,415 - 36,973,603UniSTSRnor5.0
RGSC_v3.41836,209,474 - 36,209,662UniSTSRGSC3.4
Celera1834,567,235 - 34,567,423UniSTS
Cytogenetic Map18p11UniSTS


Genetic Models
This gene Ppp2r2b is modified in the following models/strains:
F344-Ppp2r2bTn(sb-T2/Bart3)2.239Mcwi    


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001402382 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_022209 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_073588 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017601025 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017601026 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017601027 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017601028 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039097058 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039097059 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039097060 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039097062 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039097063 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039097064 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039097065 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039097066 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039097068 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039097069 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039097071 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039097072 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277526 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277527 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277528 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277529 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277531 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277532 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277533 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277534 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063277535 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AY251277 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC078834 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB692853 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473974 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D14421 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D38260 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DV721136 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FM080850 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ212581 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000018 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000041188   ⟹   ENSRNOP00000041264
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1834,653,721 - 34,764,165 (-)Ensembl
Rnor_6.0 Ensembl1836,985,714 - 37,096,132 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000079585   ⟹   ENSRNOP00000071824
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1834,654,105 - 34,952,055 (-)Ensembl
Rnor_6.0 Ensembl1836,986,162 - 37,245,809 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000091634   ⟹   ENSRNOP00000071716
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1834,653,721 - 34,952,119 (-)Ensembl
Rnor_6.0 Ensembl1836,986,095 - 37,132,223 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000097489   ⟹   ENSRNOP00000096088
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1834,653,721 - 34,952,119 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000107651   ⟹   ENSRNOP00000077436
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1834,653,721 - 35,081,025 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000112290   ⟹   ENSRNOP00000081049
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1834,653,721 - 34,952,119 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000118131   ⟹   ENSRNOP00000093860
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1834,653,721 - 34,952,119 (-)Ensembl
RefSeq Acc Id: NM_001402382   ⟹   NP_001389311
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81834,904,686 - 35,165,016 (-)NCBI
mRatBN7.21834,653,716 - 34,914,051 (-)NCBI
RefSeq Acc Id: NM_022209   ⟹   NP_071545
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81834,904,686 - 35,331,615 (-)NCBI
mRatBN7.21834,653,716 - 35,080,666 (-)NCBI
Rnor_6.01836,985,709 - 37,421,383 (-)NCBI
Rnor_5.01836,647,298 - 37,076,455 (-)NCBI
RGSC_v3.41835,865,837 - 36,318,308 (-)RGD
Celera1834,248,471 - 34,670,726 (-)NCBI
Sequence:
RefSeq Acc Id: NR_073588
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81834,904,686 - 35,203,014 (-)NCBI
mRatBN7.21834,653,716 - 34,952,055 (-)NCBI
Rnor_6.01836,985,709 - 37,291,494 (-)NCBI
Rnor_5.01836,647,298 - 37,076,455 (-)NCBI
Celera1834,248,471 - 34,542,212 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017601026   ⟹   XP_017456515
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81834,904,689 - 35,074,380 (-)NCBI
mRatBN7.21834,653,716 - 34,823,414 (-)NCBI
Rnor_6.01836,985,712 - 37,155,807 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017601028   ⟹   XP_017456517
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81834,904,689 - 35,203,059 (-)NCBI
mRatBN7.21834,653,716 - 34,952,102 (-)NCBI
Rnor_6.01836,985,712 - 37,291,538 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039097058   ⟹   XP_038952986
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81834,904,689 - 35,331,842 (-)NCBI
mRatBN7.21834,653,716 - 35,080,889 (-)NCBI
RefSeq Acc Id: XM_039097059   ⟹   XP_038952987
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81834,904,689 - 35,165,029 (-)NCBI
mRatBN7.21834,653,716 - 34,914,070 (-)NCBI
RefSeq Acc Id: XM_039097060   ⟹   XP_038952988
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81834,904,689 - 35,203,058 (-)NCBI
mRatBN7.21834,653,716 - 34,952,104 (-)NCBI
RefSeq Acc Id: XM_039097062   ⟹   XP_038952990
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81834,904,689 - 35,050,757 (-)NCBI
mRatBN7.21834,653,716 - 34,799,791 (-)NCBI
RefSeq Acc Id: XM_039097063   ⟹   XP_038952991
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81834,904,689 - 35,107,885 (-)NCBI
mRatBN7.21834,653,716 - 34,857,103 (-)NCBI
RefSeq Acc Id: XM_039097064   ⟹   XP_038952992
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81834,904,689 - 35,074,404 (-)NCBI
mRatBN7.21834,653,716 - 34,823,421 (-)NCBI
RefSeq Acc Id: XM_039097065   ⟹   XP_038952993
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81834,904,689 - 35,203,058 (-)NCBI
mRatBN7.21834,653,716 - 34,952,104 (-)NCBI
RefSeq Acc Id: XM_039097066   ⟹   XP_038952994
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81834,904,689 - 35,203,058 (-)NCBI
mRatBN7.21834,653,716 - 34,952,104 (-)NCBI
RefSeq Acc Id: XM_039097068   ⟹   XP_038952996
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81834,904,689 - 35,203,058 (-)NCBI
mRatBN7.21834,653,716 - 34,952,104 (-)NCBI
RefSeq Acc Id: XM_039097069   ⟹   XP_038952997
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81834,904,689 - 35,193,294 (-)NCBI
mRatBN7.21834,653,716 - 34,833,872 (-)NCBI
RefSeq Acc Id: XM_039097071   ⟹   XP_038952999
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81834,904,689 - 35,107,885 (-)NCBI
mRatBN7.21834,653,716 - 34,857,099 (-)NCBI
RefSeq Acc Id: XM_039097072   ⟹   XP_038953000
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81834,904,689 - 35,203,052 (-)NCBI
mRatBN7.21834,653,716 - 34,952,098 (-)NCBI
RefSeq Acc Id: XM_063277526   ⟹   XP_063133596
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81835,213,359 - 35,356,923 (-)NCBI
RefSeq Acc Id: XM_063277527   ⟹   XP_063133597
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81834,904,689 - 35,165,029 (-)NCBI
RefSeq Acc Id: XM_063277528   ⟹   XP_063133598
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81834,904,689 - 35,203,058 (-)NCBI
RefSeq Acc Id: XM_063277529   ⟹   XP_063133599
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81834,904,689 - 35,050,757 (-)NCBI
RefSeq Acc Id: XM_063277531   ⟹   XP_063133601
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81834,904,689 - 35,203,055 (-)NCBI
RefSeq Acc Id: XM_063277532   ⟹   XP_063133602
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81834,904,689 - 35,203,059 (-)NCBI
RefSeq Acc Id: XM_063277533   ⟹   XP_063133603
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81834,904,689 - 35,203,058 (-)NCBI
RefSeq Acc Id: XM_063277534   ⟹   XP_063133604
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81834,904,689 - 35,084,830 (-)NCBI
RefSeq Acc Id: XM_063277535   ⟹   XP_063133605
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81834,904,689 - 35,357,299 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001389311 (Get FASTA)   NCBI Sequence Viewer  
  NP_071545 (Get FASTA)   NCBI Sequence Viewer  
  XP_017456515 (Get FASTA)   NCBI Sequence Viewer  
  XP_017456517 (Get FASTA)   NCBI Sequence Viewer  
  XP_038952986 (Get FASTA)   NCBI Sequence Viewer  
  XP_038952987 (Get FASTA)   NCBI Sequence Viewer  
  XP_038952988 (Get FASTA)   NCBI Sequence Viewer  
  XP_038952990 (Get FASTA)   NCBI Sequence Viewer  
  XP_038952991 (Get FASTA)   NCBI Sequence Viewer  
  XP_038952992 (Get FASTA)   NCBI Sequence Viewer  
  XP_038952993 (Get FASTA)   NCBI Sequence Viewer  
  XP_038952994 (Get FASTA)   NCBI Sequence Viewer  
  XP_038952996 (Get FASTA)   NCBI Sequence Viewer  
  XP_038952997 (Get FASTA)   NCBI Sequence Viewer  
  XP_038952999 (Get FASTA)   NCBI Sequence Viewer  
  XP_038953000 (Get FASTA)   NCBI Sequence Viewer  
  XP_063133596 (Get FASTA)   NCBI Sequence Viewer  
  XP_063133597 (Get FASTA)   NCBI Sequence Viewer  
  XP_063133598 (Get FASTA)   NCBI Sequence Viewer  
  XP_063133599 (Get FASTA)   NCBI Sequence Viewer  
  XP_063133601 (Get FASTA)   NCBI Sequence Viewer  
  XP_063133602 (Get FASTA)   NCBI Sequence Viewer  
  XP_063133603 (Get FASTA)   NCBI Sequence Viewer  
  XP_063133604 (Get FASTA)   NCBI Sequence Viewer  
  XP_063133605 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH78834 (Get FASTA)   NCBI Sequence Viewer  
  AAP33142 (Get FASTA)   NCBI Sequence Viewer  
  BAA03313 (Get FASTA)   NCBI Sequence Viewer  
  BAA07412 (Get FASTA)   NCBI Sequence Viewer  
  EDL76491 (Get FASTA)   NCBI Sequence Viewer  
  EDL76492 (Get FASTA)   NCBI Sequence Viewer  
  EDL76493 (Get FASTA)   NCBI Sequence Viewer  
  EDL76494 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000041264.5
  ENSRNOP00000071716.2
  ENSRNOP00000071824.1
  ENSRNOP00000077436.1
  ENSRNOP00000081049.1
  ENSRNOP00000093860.1
  ENSRNOP00000096088.1
  ENSRNOP00055025701
  ENSRNOP00060015231
  ENSRNOP00065026410
GenBank Protein P36877 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_071545   ⟸   NM_022209
- Peptide Label: isoform 1
- UniProtKB: A6J3L0 (UniProtKB/TrEMBL),   Z4YNW7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017456517   ⟸   XM_017601028
- Peptide Label: isoform X12
- UniProtKB: A0A0G2K165 (UniProtKB/TrEMBL),   Z4YNW7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017456515   ⟸   XM_017601026
- Peptide Label: isoform X11
- UniProtKB: A0A8I5ZU97 (UniProtKB/TrEMBL),   Z4YNW7 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000041264   ⟸   ENSRNOT00000041188
Ensembl Acc Id: ENSRNOP00000071824   ⟸   ENSRNOT00000079585
Ensembl Acc Id: ENSRNOP00000071716   ⟸   ENSRNOT00000091634
RefSeq Acc Id: XP_038952986   ⟸   XM_039097058
- Peptide Label: isoform X2
- UniProtKB: Z4YNW7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038952996   ⟸   XM_039097068
- Peptide Label: isoform X7
- UniProtKB: Z4YNW7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038952993   ⟸   XM_039097065
- Peptide Label: isoform X7
- UniProtKB: Z4YNW7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038952988   ⟸   XM_039097060
- Peptide Label: isoform X3
- UniProtKB: Z4YNW7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038952994   ⟸   XM_039097066
- Peptide Label: isoform X7
- UniProtKB: Z4YNW7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038953000   ⟸   XM_039097072
- Peptide Label: isoform X14
- UniProtKB: A6K6P2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038952987   ⟸   XM_039097059
- Peptide Label: isoform X3
- UniProtKB: Z4YNW7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038952991   ⟸   XM_039097063
- Peptide Label: isoform X5
- UniProtKB: Z4YNW7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038952999   ⟸   XM_039097071
- Peptide Label: isoform X10
- UniProtKB: A0A8I6ANA4 (UniProtKB/TrEMBL),   Z4YNW7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038952997   ⟸   XM_039097069
- Peptide Label: isoform X8
- UniProtKB: Z4YNW7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038952992   ⟸   XM_039097064
- Peptide Label: isoform X6
- UniProtKB: Z4YNW7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038952990   ⟸   XM_039097062
- Peptide Label: isoform X4
- UniProtKB: Z4YNW7 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000077436   ⟸   ENSRNOT00000107651
Ensembl Acc Id: ENSRNOP00000081049   ⟸   ENSRNOT00000112290
Ensembl Acc Id: ENSRNOP00000096088   ⟸   ENSRNOT00000097489
Ensembl Acc Id: ENSRNOP00000093860   ⟸   ENSRNOT00000118131
RefSeq Acc Id: NP_001389311   ⟸   NM_001402382
- Peptide Label: isoform 2
- UniProtKB: P36877 (UniProtKB/Swiss-Prot),   Q80W84 (UniProtKB/Swiss-Prot),   A6J3L2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063133605   ⟸   XM_063277535
- Peptide Label: isoform X14
RefSeq Acc Id: XP_063133602   ⟸   XM_063277532
- Peptide Label: isoform X12
- UniProtKB: A0A0G2K165 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063133603   ⟸   XM_063277533
- Peptide Label: isoform X12
- UniProtKB: A0A0G2K165 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063133598   ⟸   XM_063277528
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063133601   ⟸   XM_063277531
- Peptide Label: isoform X12
- UniProtKB: A0A0G2K165 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063133597   ⟸   XM_063277527
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063133604   ⟸   XM_063277534
- Peptide Label: isoform X13
- UniProtKB: A0A8I6AXN0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063133599   ⟸   XM_063277529
- Peptide Label: isoform X9
RefSeq Acc Id: XP_063133596   ⟸   XM_063277526
- Peptide Label: isoform X1
Protein Domains
Reverse transcriptase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P36877-F1-model_v2 AlphaFold P36877 1-443 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:631441 AgrOrtholog
BioCyc Gene G2FUF-7693 BioCyc
Ensembl Genes ENSRNOG00000018851 Ensembl, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSRNOG00055018620 UniProtKB/Swiss-Prot
  ENSRNOG00060011432 UniProtKB/Swiss-Prot
  ENSRNOG00065019535 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000041188.5 UniProtKB/TrEMBL
  ENSRNOT00000079585.2 UniProtKB/Swiss-Prot
  ENSRNOT00000091634.2 UniProtKB/TrEMBL
  ENSRNOT00000097489.1 UniProtKB/TrEMBL
  ENSRNOT00000107651.1 UniProtKB/Swiss-Prot
  ENSRNOT00000112290.1 UniProtKB/TrEMBL
  ENSRNOT00000118131.1 UniProtKB/TrEMBL
  ENSRNOT00055031785 UniProtKB/Swiss-Prot
  ENSRNOT00060019414 UniProtKB/Swiss-Prot
  ENSRNOT00065033044 UniProtKB/Swiss-Prot
Gene3D-CATH 2.130.10.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Endonuclease/exonuclease/phosphatase UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7114294 IMAGE-MGC_LOAD
InterPro DNA/RNA_pol_sf UniProtKB/TrEMBL
  Endo/exonu/phosph_ase_sf UniProtKB/TrEMBL
  PP2A_PR55 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PP2A_PR55_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RT_dom UniProtKB/TrEMBL
  WD40/YVTN_repeat-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD40_repeat UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD40_repeat_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:60660 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:93454 IMAGE-MGC_LOAD
NCBI Gene 60660 ENTREZGENE
PANTHER LINE-1 RETROTRANSPOSABLE ELEMENT ORF2 PROTEIN UniProtKB/TrEMBL
  PTHR11871 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  REVERSE TRANSCRIPTASES UniProtKB/TrEMBL
  SERINE/THREONINE-PROTEIN PHOSPHATASE 2A 55 KDA REGULATORY SUBUNIT B ALPHA ISOFORM UniProtKB/TrEMBL
  SERINE/THREONINE-PROTEIN PHOSPHATASE 2A 55 KDA REGULATORY SUBUNIT B BETA ISOFORM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam RVT_1 UniProtKB/TrEMBL
  WD40 UniProtKB/TrEMBL
PhenoGen Ppp2r2b PhenoGen
PIRSF PP2A_PR55 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS PP2APR55 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE PR55_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PR55_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RT_POL UniProtKB/TrEMBL
  WD_REPEATS_1 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000018851 RatGTEx
  ENSRNOG00055018620 RatGTEx
  ENSRNOG00060011432 RatGTEx
  ENSRNOG00065019535 RatGTEx
SMART WD40 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP DNA/RNA polymerases UniProtKB/TrEMBL
  DNase I-like UniProtKB/TrEMBL
  SSF50978 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt 2ABB_RAT UniProtKB/Swiss-Prot
  A0A0G2K165 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZU97 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6ANA4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AXN0 ENTREZGENE, UniProtKB/TrEMBL
  A6J3K9_RAT UniProtKB/TrEMBL
  A6J3L0 ENTREZGENE, UniProtKB/TrEMBL
  A6J3L2 ENTREZGENE, UniProtKB/TrEMBL
  A6K6P2 ENTREZGENE, UniProtKB/TrEMBL
  A6K9H8_RAT UniProtKB/TrEMBL
  P36877 ENTREZGENE
  Q80W84 ENTREZGENE
  Z4YNW7 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary Q80W84 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2004-09-10 Ppp2r2b  protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform  Pppr2b2    Symbol updated 1299863 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_expression expressed in brain and testis 633587