Diaph1 (diaphanous-related formin 1) - Rat Genome Database

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Gene: Diaph1 (diaphanous-related formin 1) Rattus norvegicus
Analyze
Symbol: Diaph1
Name: diaphanous-related formin 1
RGD ID: 1310707
Description: Predicted to enable several functions, including profilin binding activity; small GTPase binding activity; and transmembrane transporter binding activity. Involved in positive regulation of cell migration. Predicted to be located in several cellular components, including brush border; mitotic spindle; and ruffle membrane. Predicted to be active in actin filament. Predicted to colocalize with spindle microtubule. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 1 and sensorineural hearing loss. Orthologous to human DIAPH1 (diaphanous related formin 1); PARTICIPATES IN E-cadherin signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Diap1; diaphanous homolog 1; diaphanous homolog 1 (Drosophila); DRF1; LOC307483; mDIA1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21829,669,659 - 29,769,044 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1829,669,659 - 29,769,172 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1829,773,984 - 29,873,376 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.01830,535,964 - 30,635,353 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.01829,871,305 - 29,970,698 (-)NCBIRnor_WKY
Rnor_6.01830,972,907 - 31,071,371 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1830,972,907 - 31,071,371 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01830,663,859 - 30,762,658 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41830,757,191 - 30,855,548 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11830,784,366 - 30,882,101 (-)NCBI
Celera1829,313,748 - 29,412,995 (-)NCBICelera
Cytogenetic Map18p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Nonsyndromic deafness DFNA1 associated with mutation of a human homolog of the Drosophila gene diaphanous. Lynch ED, etal., Science. 1997 Nov 14;278(5341):1315-8.
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
6. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
7. GOA pipeline RGD automated data pipeline
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. Comprehensive gene review and curation RGD comprehensive gene curation
11. The Rho-mDia1 pathway regulates cell polarity and focal adhesion turnover in migrating cells through mobilizing Apc and c-Src. Yamana N, etal., Mol Cell Biol. 2006 Sep;26(18):6844-58.
Additional References at PubMed
PMID:9214622   PMID:10559899   PMID:12906795   PMID:14992721   PMID:15123714   PMID:16472745   PMID:17170370   PMID:18362183   PMID:18572016   PMID:18651670   PMID:20071339   PMID:20937854  
PMID:21834987   PMID:22114352   PMID:22658674   PMID:23558171   PMID:24781755   PMID:26912466   PMID:28877993   PMID:30358011  


Genomics

Comparative Map Data
Diaph1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21829,669,659 - 29,769,044 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1829,669,659 - 29,769,172 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1829,773,984 - 29,873,376 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.01830,535,964 - 30,635,353 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.01829,871,305 - 29,970,698 (-)NCBIRnor_WKY
Rnor_6.01830,972,907 - 31,071,371 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1830,972,907 - 31,071,371 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01830,663,859 - 30,762,658 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41830,757,191 - 30,855,548 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11830,784,366 - 30,882,101 (-)NCBI
Celera1829,313,748 - 29,412,995 (-)NCBICelera
Cytogenetic Map18p11NCBI
DIAPH1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385141,515,021 - 141,619,000 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl5141,515,016 - 141,619,055 (-)EnsemblGRCh38hg38GRCh38
GRCh375140,894,588 - 140,998,567 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 365140,874,772 - 140,978,747 (-)NCBINCBI36Build 36hg18NCBI36
Build 345140,874,772 - 140,978,691NCBI
Celera5136,971,324 - 137,075,350 (-)NCBICelera
Cytogenetic Map5q31.3NCBI
HuRef5136,039,428 - 136,143,262 (-)NCBIHuRef
CHM1_15140,327,865 - 140,431,904 (-)NCBICHM1_1
T2T-CHM13v2.05142,041,005 - 142,145,005 (-)NCBIT2T-CHM13v2.0
Diaph1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391837,976,654 - 38,068,573 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1837,976,654 - 38,068,529 (-)EnsemblGRCm39 Ensembl
GRCm381837,843,601 - 37,935,622 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1837,843,601 - 37,935,476 (-)EnsemblGRCm38mm10GRCm38
MGSCv371838,004,478 - 38,095,065 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361837,970,798 - 38,061,385 (-)NCBIMGSCv36mm8
Celera1839,188,303 - 39,278,736 (-)NCBICelera
Cytogenetic Map18B3NCBI
cM Map1819.71NCBI
Diaph1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541512,156,152 - 12,272,961 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541512,156,152 - 12,272,961 (+)NCBIChiLan1.0ChiLan1.0
DIAPH1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.15142,990,248 - 143,092,558 (-)NCBIpanpan1.1PanPan1.1panPan2
Mhudiblu_PPA_v05136,876,396 - 136,980,097 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
DIAPH1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1236,483,781 - 36,581,390 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl236,485,571 - 36,581,320 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha233,535,791 - 33,633,355 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0236,937,687 - 37,035,539 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl236,937,690 - 37,035,611 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1234,012,555 - 34,110,155 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0234,824,079 - 34,921,683 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0235,631,288 - 35,728,900 (-)NCBIUU_Cfam_GSD_1.0
Diaph1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213150,974,209 - 151,071,265 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493650412,548,452 - 12,643,399 (+)EnsemblSpeTri2.0
SpeTri2.0NW_00493650412,548,452 - 12,645,236 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DIAPH1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2143,158,585 - 143,271,147 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12143,158,691 - 143,271,110 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22149,363,162 - 149,473,567 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DIAPH1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12344,139,495 - 44,244,505 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2344,139,360 - 44,244,490 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603433,608,326 - 33,713,597 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Diaph1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624774739,206 - 845,272 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624774738,717 - 845,187 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Diaph1
260 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:235
Count of miRNA genes:103
Interacting mature miRNAs:109
Transcripts:ENSRNOT00000060432, ENSRNOT00000060433
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2312598Bp340Blood pressure QTL 3400.05arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)18130558703Rat
2300180Bmd67Bone mineral density QTL 674.80.0001femur mineral mass (VT:0010011)bone mineral density (CMO:0001226)18134291613Rat
2293661Bss50Bone structure and strength QTL 504.640.0003lumbar vertebra size trait (VT:0010518)lumbar vertebra trabecular cross-sectional area (CMO:0001692)18134291613Rat
61388Bp2Blood pressure QTL 23.23arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)18135374722Rat
9589153Insul31Insulin level QTL 317.150.05blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)18142547119Rat
2299160Iddm35Insulin dependent diabetes mellitus QTL 352.79blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)18420794160377792Rat
2312568Glom21Glomerulus QTL 2120.005kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)18518585840503530Rat
2293708Bss46Bone structure and strength QTL 468.80.0001lumbar vertebra morphology trait (VT:0010494)lumbar vertebra cortical cross-sectional area (CMO:0001690)181179151863636873Rat
1578661Bss20Bone structure and strength QTL 203.7femur morphology trait (VT:0000559)femoral neck cross-sectional area (CMO:0001697)181179151883218561Rat
1578667Bss21Bone structure and strength QTL 213.5femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)181179151883218561Rat
61382Bp46Blood pressure QTL 4618.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)181194179131393320Rat
631264Scl22Serum cholesterol level QTL 226.2blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)181194179131393320Rat
1331766Bp236Blood pressure QTL 2363.022arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)181194429931359530Rat
61375Bp41Blood pressure QTL 412.4blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)181194429941122201Rat
1331753Bp231Blood pressure QTL 2313.643arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)181194429952293055Rat
1358358Sradr6Stress Responsive Adrenal Weight QTL 62.49adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)181194429959330563Rat
6903359Bp355Blood pressure QTL 3553.6arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)181194454459796478Rat
2313082Bss85Bone structure and strength QTL 850.80.0001long bone metaphysis morphology trait (VT:0000133)tibia midshaft total cross-sectional area (CMO:0001715)181495133759951337Rat
1358193Emca2Estrogen-induced mammary cancer QTL 21.6mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)181800759963571040Rat
1331735Rf44Renal function QTL 442.981urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)181823456431359530Rat
1331775Bp235Blood pressure QTL 2353.201arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)181823456431359530Rat
1600373Mamtr6Mammary tumor resistance QTL 6mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)181927890183218561Rat
1331741Bp232Blood pressure QTL 2323.59112arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)182137289383213037Rat
1641923Colcr8Colorectal carcinoma resistance QTL 83.10.0014intestine integrity trait (VT:0010554)poorly differentiated malignant colorectal tumor number (CMO:0002076)182206624252293055Rat
1331733Bp233Blood pressure QTL 2333.97196arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)182479697779788953Rat
2325839Bp348Blood pressure QTL 3480.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)182557098570570985Rat
12904673Cm127Cardiac mass QTL 1270.005heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)182654808246969551Rat
12904675Am19Aortic mass QTL 190.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)182654808246969551Rat
12904677Kidm72Kidney mass QTL 720.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)182654808246969551Rat
12904668Bw188Body weight QTL 1880.03body mass (VT:0001259)body weight (CMO:0000012)182654808246969551Rat
12904669Cm125Cardiac mass QTL 1250.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)182654808246969551Rat
12904670Cm126Cardiac mass QTL 1260.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)182654808246969551Rat
2301413Bp318Blood pressure QTL 3180.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)182654808246969551Rat
2293704Bss35Bone structure and strength QTL 354.590.0002femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)182896485373964853Rat
2300157Bmd66Bone mineral density QTL 6613.10.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)182896485373964853Rat
2300177Bmd65Bone mineral density QTL 6519.70.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)182896485373964853Rat

Markers in Region
RH130783  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21829,770,659 - 29,770,857 (+)MAPPERmRatBN7.2
Rnor_6.01831,072,987 - 31,073,184NCBIRnor6.0
Rnor_5.01830,764,274 - 30,764,471UniSTSRnor5.0
RGSC_v3.41830,857,139 - 30,857,336UniSTSRGSC3.4
Celera1829,414,611 - 29,414,808UniSTS
RH 3.4 Map18444.2UniSTS
Cytogenetic Map18p11UniSTS
RH127883  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21829,669,684 - 29,669,893 (+)MAPPERmRatBN7.2
Rnor_6.01830,972,933 - 30,973,141NCBIRnor6.0
Rnor_5.01830,663,885 - 30,664,093UniSTSRnor5.0
RGSC_v3.41830,756,025 - 30,756,233UniSTSRGSC3.4
Celera1829,313,774 - 29,313,982UniSTS
Cytogenetic Map18p11UniSTS
BE119953  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2247,231,083 - 47,231,306 (+)MAPPERmRatBN7.2
mRatBN7.21829,730,201 - 29,730,413 (+)MAPPERmRatBN7.2
Rnor_6.01831,032,769 - 31,032,980NCBIRnor6.0
Rnor_6.0247,876,688 - 47,876,910NCBIRnor6.0
Rnor_5.01830,724,159 - 30,724,370UniSTSRnor5.0
Rnor_5.0266,264,138 - 66,264,360UniSTSRnor5.0
RGSC_v3.4246,345,568 - 46,345,790UniSTSRGSC3.4
RGSC_v3.41830,816,539 - 30,816,750UniSTSRGSC3.4
Celera1829,374,164 - 29,374,375UniSTS
Celera242,965,202 - 42,965,424UniSTS
RH 3.4 Map18428.3UniSTS
Cytogenetic Map18p11UniSTS
Cytogenetic Map2q14UniSTS
RH124673  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21829,669,710 - 29,670,024 (+)MAPPERmRatBN7.2
Rnor_6.01830,972,959 - 30,973,272NCBIRnor6.0
Rnor_5.01830,663,911 - 30,664,224UniSTSRnor5.0
RGSC_v3.41830,756,051 - 30,756,364UniSTSRGSC3.4
Celera1829,313,800 - 29,314,113UniSTS
Cytogenetic Map18p11UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 26 56 41 19 41 4 7 66 35 41 11 4
Low 17 1 4 4 8 4
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000060432   ⟹   ENSRNOP00000057176
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1829,669,659 - 29,769,044 (-)Ensembl
Rnor_6.0 Ensembl1830,972,907 - 31,071,371 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000102970   ⟹   ENSRNOP00000088426
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1829,669,659 - 29,769,172 (-)Ensembl
RefSeq Acc Id: NM_001107393   ⟹   NP_001100863
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21829,669,659 - 29,769,044 (-)NCBI
Rnor_6.01830,972,907 - 31,071,371 (-)NCBI
Rnor_5.01830,663,859 - 30,762,658 (-)NCBI
RGSC_v3.41830,757,191 - 30,855,548 (-)RGD
Celera1829,313,748 - 29,412,995 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001100863 (Get FASTA)   NCBI Sequence Viewer  
  NP_001382031 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL76410 (Get FASTA)   NCBI Sequence Viewer  
  EDL76411 (Get FASTA)   NCBI Sequence Viewer  
  EDL76412 (Get FASTA)   NCBI Sequence Viewer  
  F1M775 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001100863   ⟸   NM_001107393
- UniProtKB: A0A8L2QTN9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000057176   ⟸   ENSRNOT00000060432
RefSeq Acc Id: ENSRNOP00000088426   ⟸   ENSRNOT00000102970
Protein Domains
DAD   FH1   FH2   GBD/FH3

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13700736
Promoter ID:EPDNEW_R11260
Type:initiation region
Name:Diaph1_1
Description:diaphanous-related formin 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01831,071,369 - 31,071,429EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1310707 AgrOrtholog
BioCyc Gene G2FUF-7792 BioCyc
Ensembl Genes ENSRNOG00000019688 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000057176 ENTREZGENE
  ENSRNOP00000057176.5 UniProtKB/TrEMBL
  ENSRNOP00000088426.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000060432 ENTREZGENE
  ENSRNOT00000060432.6 UniProtKB/TrEMBL
  ENSRNOT00000102970.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.20.40 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  1.20.58.2220 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  1.25.10.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro ARM-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ARM-type_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DAD_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DIA_GBD_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FH2_Formin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FH2_Formin_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FH3_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Formin_Diaph1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GBD/FH3_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GTPase-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 307483 ENTREZGENE
PANTHER PTHR45691:SF4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Drf_FH3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Drf_GBD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FH2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Diaph1 PhenoGen
PROSITE DAD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FH2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GBD_FH3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART Drf_FH3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Drf_GBD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FH2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48371 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I6A828 ENTREZGENE, UniProtKB/TrEMBL
  A0A8L2QTN9 ENTREZGENE, UniProtKB/TrEMBL
  DIAP1_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-06-05 Diaph1  diaphanous-related formin 1  Diaph1  diaphanous homolog 1 (Drosophila)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-09-26 Diaph1  diaphanous homolog 1 (Drosophila)  Diap1  diaphanous homolog 1 (Drosophila)   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Diap1  diaphanous homolog 1 (Drosophila)   Diap1_predicted  diaphanous homolog 1 (Drosophila) (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Diap1_predicted  diaphanous homolog 1 (Drosophila) (predicted)      Symbol and Name status set to approved 70820 APPROVED