Ik (IK cytokine) - Rat Genome Database

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Gene: Ik (IK cytokine) Rattus norvegicus
Analyze
Symbol: Ik (Ensembl: Wdr55)
Name: IK cytokine (Ensembl:WD repeat domain 55)
RGD ID: 1359352
Description: Predicted to enable identical protein binding activity. Predicted to be involved in mRNA splicing, via spliceosome; mitotic spindle assembly checkpoint signaling; and protein localization to kinetochore. Predicted to be located in nuclear speck. Predicted to be part of U2-type precatalytic spliceosome. Predicted to be active in nucleus. Predicted to colocalize with mitotic spindle pole and nuclear chromosome. Orthologous to human IK (IK cytokine); INTERACTS WITH 2,4-dibromophenyl 2,4,5-tribromophenyl ether; 2,4-dinitrotoluene; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: chondrosarcoma-associated protein 2; CSA2; cytokine IK; IK cytokine, down-regulator of HLA II; Ik factor; MGC93710; RED
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21828,358,004 - 28,372,809 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1828,357,977 - 28,378,832 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1828,485,154 - 28,499,958 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01829,247,228 - 29,262,032 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01828,582,456 - 28,597,260 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01829,587,901 - 29,602,705 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1829,587,901 - 29,608,338 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01829,291,708 - 29,306,512 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41829,444,004 - 29,458,808 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11829,470,649 - 29,485,454 (+)NCBI
Celera1828,078,557 - 28,093,361 (+)NCBICelera
Cytogenetic Map18p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA)
membrane  (IEA)
mitotic spindle pole  (ISO,ISS)
nuclear chromosome  (ISO,ISS)
nuclear speck  (ISO)
nucleoplasm  (ISO,ISS)
nucleus  (IBA,IEA,ISO,ISS)
U2-type precatalytic spliceosome  (ISO,ISS)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. A new cytokine (IK) down-regulating HLA class II: monoclonal antibodies, cloning and chromosome localization. Krief P, etal., Oncogene 1994 Dec;9(12):3449-56.
4. GOA pipeline RGD automated data pipeline
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:22351768   PMID:22365833   PMID:24252166   PMID:28781166  


Genomics

Comparative Map Data
Ik
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21828,358,004 - 28,372,809 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1828,357,977 - 28,378,832 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1828,485,154 - 28,499,958 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01829,247,228 - 29,262,032 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01828,582,456 - 28,597,260 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01829,587,901 - 29,602,705 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1829,587,901 - 29,608,338 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01829,291,708 - 29,306,512 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41829,444,004 - 29,458,808 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11829,470,649 - 29,485,454 (+)NCBI
Celera1828,078,557 - 28,093,361 (+)NCBICelera
Cytogenetic Map18p11NCBI
IK
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385140,647,829 - 140,662,480 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5140,647,058 - 140,662,480 (+)EnsemblGRCh38hg38GRCh38
GRCh375140,027,414 - 140,042,065 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365140,007,568 - 140,022,249 (+)NCBINCBI36Build 36hg18NCBI36
Build 345140,007,567 - 140,022,098NCBI
Celera5136,104,129 - 136,118,812 (+)NCBICelera
Cytogenetic Map5q31.3ENTREZGENE
HuRef5135,172,621 - 135,187,305 (+)ENTREZGENEHuRef
CHM1_15139,460,619 - 139,475,314 (+)NCBICHM1_1
T2T-CHM13v2.05141,173,235 - 141,187,876 (+)NCBIT2T-CHM13v2.0
Ik
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391836,877,709 - 36,890,692 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1836,877,731 - 36,890,688 (+)EnsemblGRCm39 Ensembl
GRCm381836,744,656 - 36,757,639 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1836,744,656 - 36,757,639 (+)EnsemblGRCm38mm10GRCm38
MGSCv371836,904,310 - 36,917,293 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361836,870,690 - 36,883,609 (+)NCBIMGSCv36mm8
Celera1837,196,721 - 37,209,702 (+)NCBICelera
Cytogenetic Map18B2NCBI
cM Map1819.46NCBI
Ik
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541839,695 - 52,862 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541839,695 - 52,862 (-)NCBIChiLan1.0ChiLan1.0
IK
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan15134,045,089 - 134,059,818 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05136,012,381 - 136,027,099 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15142,129,130 - 142,143,393 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5142,129,130 - 142,143,393 (+)Ensemblpanpan1.1panPan2
IK
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1235,805,631 - 35,818,205 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl235,805,689 - 35,818,050 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha232,844,638 - 32,857,193 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0236,261,280 - 36,273,815 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl236,261,332 - 36,273,809 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1233,313,649 - 33,326,167 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0234,181,413 - 34,193,941 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0234,934,115 - 34,946,646 (+)NCBIUU_Cfam_GSD_1.0
Ik
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213152,010,239 - 152,022,723 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365319,588,555 - 9,601,293 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365319,589,035 - 9,601,266 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IK
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2142,361,155 - 142,376,333 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12142,361,134 - 142,376,335 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22148,305,095 - 148,320,513 (+)NCBISscrofa10.2Sscrofa10.2susScr3
IK
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12343,280,876 - 43,295,844 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2343,280,981 - 43,297,843 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603434,588,676 - 34,603,675 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ik
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474333,400,459 - 33,413,993 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474333,400,359 - 33,413,993 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Ik
37 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:37
Count of miRNA genes:36
Interacting mature miRNAs:37
Transcripts:ENSRNOT00000012906
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2312598Bp340Blood pressure QTL 3400.05arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)18130558703Rat
2300180Bmd67Bone mineral density QTL 674.80.0001femur mineral mass (VT:0010011)bone mineral density (CMO:0001226)18134291613Rat
2293661Bss50Bone structure and strength QTL 504.640.0003lumbar vertebra size trait (VT:0010518)lumbar vertebra trabecular cross-sectional area (CMO:0001692)18134291613Rat
61388Bp2Blood pressure QTL 23.23arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)18135374722Rat
9589153Insul31Insulin level QTL 317.150.05blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)18142547119Rat
2299160Iddm35Insulin dependent diabetes mellitus QTL 352.79blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)18420794160377792Rat
2312568Glom21Glomerulus QTL 2120.005kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)18518585840503530Rat
2293708Bss46Bone structure and strength QTL 468.80.0001lumbar vertebra morphology trait (VT:0010494)lumbar vertebra cortical cross-sectional area (CMO:0001690)181179151863636873Rat
1578661Bss20Bone structure and strength QTL 203.7femur morphology trait (VT:0000559)femoral neck cross-sectional area (CMO:0001697)181179151883218561Rat
1578667Bss21Bone structure and strength QTL 213.5femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)181179151883218561Rat
61382Bp46Blood pressure QTL 4618.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)181194179131393320Rat
631264Scl22Serum cholesterol level QTL 226.2blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)181194179131393320Rat
1331766Bp236Blood pressure QTL 2363.022arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)181194429931359530Rat
61375Bp41Blood pressure QTL 412.4blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)181194429941122201Rat
1331753Bp231Blood pressure QTL 2313.643arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)181194429952293055Rat
1358358Sradr6Stress Responsive Adrenal Weight QTL 62.49adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)181194429959330563Rat
6903359Bp355Blood pressure QTL 3553.6arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)181194454459796478Rat
2313082Bss85Bone structure and strength QTL 850.80.0001long bone metaphysis morphology trait (VT:0000133)tibia midshaft total cross-sectional area (CMO:0001715)181495133759951337Rat
1358193Emca2Estrogen-induced mammary cancer QTL 21.6mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)181800759963571040Rat
1331735Rf44Renal function QTL 442.981urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)181823456431359530Rat
1331775Bp235Blood pressure QTL 2353.201arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)181823456431359530Rat
1600373Mamtr6Mammary tumor resistance QTL 6mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)181927890183218561Rat
1331741Bp232Blood pressure QTL 2323.59112arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)182137289383213037Rat
1641923Colcr8Colorectal carcinoma resistance QTL 83.10.0014intestine integrity trait (VT:0010554)poorly differentiated malignant colorectal tumor number (CMO:0002076)182206624252293055Rat
1331733Bp233Blood pressure QTL 2333.97196arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)182479697779788953Rat
2325839Bp348Blood pressure QTL 3480.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)182557098570570985Rat
12904673Cm127Cardiac mass QTL 1270.005heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)182654808246969551Rat
12904675Am19Aortic mass QTL 190.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)182654808246969551Rat
12904677Kidm72Kidney mass QTL 720.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)182654808246969551Rat
12904668Bw188Body weight QTL 1880.03body mass (VT:0001259)body weight (CMO:0000012)182654808246969551Rat
12904669Cm125Cardiac mass QTL 1250.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)182654808246969551Rat
12904670Cm126Cardiac mass QTL 1260.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)182654808246969551Rat
2301413Bp318Blood pressure QTL 3180.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)182654808246969551Rat

Markers in Region
RH142378  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21828,372,608 - 28,372,787 (+)MAPPERmRatBN7.2
Rnor_6.01829,602,505 - 29,602,683NCBIRnor6.0
Rnor_5.01829,306,312 - 29,306,490UniSTSRnor5.0
RGSC_v3.41829,458,608 - 29,458,786UniSTSRGSC3.4
Celera1828,093,161 - 28,093,339UniSTS
RH 3.4 Map18416.89UniSTS
Cytogenetic Map18p11UniSTS
RH143679  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21828,369,379 - 28,369,539 (+)MAPPERmRatBN7.2
Rnor_6.01829,599,277 - 29,599,436NCBIRnor6.0
Rnor_5.01829,303,084 - 29,303,243UniSTSRnor5.0
RGSC_v3.41829,455,380 - 29,455,539UniSTSRGSC3.4
Celera1828,089,933 - 28,090,092UniSTS
RH 3.4 Map18416.7UniSTS
Cytogenetic Map18p11UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 57 41 19 41 8 11 74 35 41 11 8
Low
Below cutoff

Sequence


RefSeq Acc Id: ENSRNOT00000043271   ⟹   ENSRNOP00000044213
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1828,357,977 - 28,378,832 (+)Ensembl
Rnor_6.0 Ensembl1829,591,611 - 29,608,338 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000085470   ⟹   ENSRNOP00000073422
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1828,357,977 - 28,372,810 (+)Ensembl
Rnor_6.0 Ensembl1829,587,901 - 29,602,705 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000097588   ⟹   ENSRNOP00000096480
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1828,357,977 - 28,372,895 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000101628   ⟹   ENSRNOP00000095676
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1828,357,977 - 28,378,832 (+)Ensembl
RefSeq Acc Id: NM_001005537   ⟹   NP_001005537
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21828,358,004 - 28,372,809 (+)NCBI
Rnor_6.01829,587,901 - 29,602,705 (+)NCBI
Rnor_5.01829,291,708 - 29,306,512 (+)NCBI
RGSC_v3.41829,444,004 - 29,458,808 (+)RGD
Celera1828,078,557 - 28,093,361 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001005537 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH81870 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000073422
  ENSRNOP00000073422.2
  ENSRNOP00000095676.1
  ENSRNOP00000096480.1
  ENSRNOP00065016214
GenBank Protein Q66HG8 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001005537   ⟸   NM_001005537
- UniProtKB: Q66HG8 (UniProtKB/Swiss-Prot),   A6J330 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000044213   ⟸   ENSRNOT00000043271
RefSeq Acc Id: ENSRNOP00000073422   ⟸   ENSRNOT00000085470
RefSeq Acc Id: ENSRNOP00000096480   ⟸   ENSRNOT00000097588
RefSeq Acc Id: ENSRNOP00000095676   ⟸   ENSRNOT00000101628
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q66HG8-F1-model_v2 AlphaFold Q66HG8 1-557 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13700729
Promoter ID:EPDNEW_R11253
Type:initiation region
Name:Ik_1
Description:IK cytokine
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01829,587,884 - 29,587,944EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1359352 AgrOrtholog
BioCyc Gene G2FUF-7861 BioCyc
Ensembl Genes ENSRNOG00000017251 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOG00065012846 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000085470 ENTREZGENE
  ENSRNOT00000085470.2 UniProtKB/TrEMBL
  ENSRNOT00000097588.1 UniProtKB/TrEMBL
  ENSRNOT00000101628.1 UniProtKB/TrEMBL
  ENSRNOT00065021011 UniProtKB/Swiss-Prot
Gene3D-CATH 2.130.10.10 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7106138 IMAGE-MGC_LOAD
InterPro Apc4_WD40_dom UniProtKB/TrEMBL
  Red-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RED_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RED_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD40/YVTN_repeat-like_dom_sf UniProtKB/TrEMBL
  WD40_repeat UniProtKB/TrEMBL
  WD40_repeat_CS UniProtKB/TrEMBL
  WD40_repeat_dom_sf UniProtKB/TrEMBL
KEGG Report rno:291659 UniProtKB/Swiss-Prot
MGC_CLONE MGC:93710 IMAGE-MGC_LOAD
NCBI Gene 291659 ENTREZGENE
PANTHER PROTEIN RED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR12765 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam ANAPC4_WD40 UniProtKB/TrEMBL
  RED_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RED_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD40 UniProtKB/TrEMBL
PhenoGen Ik PhenoGen
PROSITE WD_REPEATS_1 UniProtKB/TrEMBL
  WD_REPEATS_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000017251 RatGTEx
  ENSRNOG00065012846 RatGTEx
SMART WD40 UniProtKB/TrEMBL
Superfamily-SCOP SSF50978 UniProtKB/TrEMBL
UniProt A0A0G2K5G9_RAT UniProtKB/TrEMBL
  A0A8I6APP6_RAT UniProtKB/TrEMBL
  A0A8I6GLR2_RAT UniProtKB/TrEMBL
  A6J330 ENTREZGENE, UniProtKB/TrEMBL
  Q66HG8 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-10-19 Ik  IK cytokine  Ik  IK cytokine, down-regulator of HLA II  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-07-17 Ik  IK cytokine, down-regulator of HLA II  Ik  Ik cytokine  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-01-12 Ik  Ik cytokine  Ik  IK cytokine  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-11-17 Ik  IK cytokine      Name updated 1299863 APPROVED
2005-07-29 Ik  RED protein      Symbol and Name status set to provisional 70820 PROVISIONAL