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Gene: Mcc (MCC regulator of WNT signaling pathway) Rattus norvegicus
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Symbol: Mcc
Name: MCC regulator of WNT signaling pathway
Description: Predicted to have calcium ion binding activity. Predicted to be involved in several processes, including negative regulation of canonical Wnt signaling pathway; negative regulation of epithelial cell migration; and negative regulation of epithelial cell proliferation. Predicted to localize to several cellular components, including the cytoplasmic ribonucleoprotein granule; cytosol; and nucleoplasm. Orthologous to human MCC (MCC regulator of WNT signaling pathway); INTERACTS WITH (+)-schisandrin B; 1,2-dimethylhydrazine; amphetamine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: LOC307449; MCC, WNT signaling pathway regulator; mutated in colorectal cancers; RGD1561988; similar to Colorectal mutant cancer protein (MCC protein)
Orthologs:
Homo sapiens (human) : MCC (MCC regulator of WNT signaling pathway)  HGNC  Alliance
Sus scrofa (pig) : MCC (MCC regulator of WNT signaling pathway)
Chlorocebus sabaeus (African green monkey) : MCC (MCC regulator of WNT signaling pathway)
Heterocephalus glaber (naked mole-rat) : Mcc (MCC regulator of WNT signaling pathway)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: suggests misassembly; Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01835,683,185 - 35,817,117 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0112,006,663 - 12,128,849 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl112,006,660 - 12,128,845 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl1835,683,185 - 35,817,127 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01835,348,808 - 35,484,229 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.0113,595,971 - 13,952,963 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41838,099,803 - 38,576,214NCBIRGSC3.4rn4RGSC3.4
Cytogenetic Map18p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Mcc
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1561988
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2020-03-04
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.