Mcc (MCC regulator of WNT signaling pathway) - Rat Genome Database

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Gene: Mcc (MCC regulator of WNT signaling pathway) Rattus norvegicus
Analyze
Symbol: Mcc
Name: MCC regulator of WNT signaling pathway
RGD ID: 1561988
Description: Predicted to enable calcium ion binding activity. Predicted to be involved in several processes, including negative regulation of canonical Wnt signaling pathway; negative regulation of epithelial cell migration; and negative regulation of epithelial cell proliferation. Predicted to be located in several cellular components, including cytoplasmic ribonucleoprotein granule; cytosol; and nucleoplasm. Human ortholog(s) of this gene implicated in colorectal cancer. Orthologous to human MCC (MCC regulator of WNT signaling pathway); INTERACTS WITH (+)-schisandrin B; 1,2-dimethylhydrazine; amphetamine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: colorectal mutant cancer protein-like; LOC100909795; LOC307449; MCC, WNT signaling pathway regulator; mutated in colorectal cancers; RGD1561988; similar to Colorectal mutant cancer protein (MCC protein)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21836,794,206 - 37,266,237 (-)NCBI
Rnor_6.0 Ensembl112,006,660 - 12,128,845 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl1835,683,185 - 35,817,127 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01835,683,185 - 35,817,117 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0112,006,663 - 12,128,849 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0113,595,971 - 13,952,963 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.01835,348,808 - 35,484,229 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41838,099,803 - 38,576,214NCBIRGSC3.4rn4RGSC3.4
Cytogenetic Map18p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (EXP)
17beta-estradiol  (ISO)
17beta-hydroxy-17-methylestra-4,9,11-trien-3-one  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2-hydroxypropanoic acid  (ISO)
4-hydroxyphenyl retinamide  (ISO)
afimoxifene  (ISO)
aflatoxin B1  (ISO)
aflatoxin B2  (ISO)
amphetamine  (EXP)
antirheumatic drug  (ISO)
aristolochic acid  (ISO)
benzo[a]pyrene  (ISO)
benzo[e]pyrene  (ISO)
bisphenol A  (EXP)
buta-1,3-diene  (ISO)
cadmium dichloride  (ISO)
carbon nanotube  (ISO)
chloroprene  (ISO)
choline  (ISO)
crocidolite asbestos  (ISO)
cyclosporin A  (ISO)
dexamethasone  (ISO)
dichromium trioxide  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
entinostat  (ISO)
ethyl methanesulfonate  (ISO)
fluoranthene  (ISO)
folic acid  (ISO)
formaldehyde  (ISO)
L-methionine  (ISO)
lead diacetate  (ISO)
leflunomide  (ISO)
mercury dibromide  (ISO)
methamphetamine  (EXP)
methapyrilene  (ISO)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
nickel sulfate  (ISO)
oxybenzone  (EXP)
ozone  (EXP)
p-chloromercuribenzoic acid  (ISO)
panobinostat  (ISO)
paracetamol  (ISO)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
potassium chromate  (ISO)
potassium dichromate  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
propiconazole  (ISO)
rac-lactic acid  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sunitinib  (ISO)
tetrachloromethane  (EXP,ISO)
trichostatin A  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

Additional References at PubMed
PMID:1848370   PMID:18591935   PMID:19555689   PMID:24824780  


Genomics

Comparative Map Data
Mcc
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21836,794,206 - 37,266,237 (-)NCBI
Rnor_6.0 Ensembl112,006,660 - 12,128,845 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl1835,683,185 - 35,817,127 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01835,683,185 - 35,817,117 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0112,006,663 - 12,128,849 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0113,595,971 - 13,952,963 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.01835,348,808 - 35,484,229 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41838,099,803 - 38,576,214NCBIRGSC3.4rn4RGSC3.4
Cytogenetic Map18p11NCBI
MCC
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl5113,022,099 - 113,488,823 (-)EnsemblGRCh38hg38GRCh38
GRCh385113,022,106 - 113,488,453 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh375112,357,803 - 112,824,150 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 365112,385,695 - 112,852,426 (-)NCBINCBI36hg18NCBI36
Build 345112,389,427 - 112,658,201NCBI
Celera5108,303,413 - 108,772,341 (-)NCBI
Cytogenetic Map5q22.2NCBI
HuRef5107,537,529 - 108,007,449 (-)NCBIHuRef
CHM1_15111,791,093 - 112,258,011 (-)NCBICHM1_1
Mcc
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391844,558,127 - 44,945,573 (-)NCBIGRCm39mm39
GRCm39 Ensembl1844,558,127 - 44,945,249 (-)Ensembl
GRCm381844,425,060 - 44,812,182 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1844,425,060 - 44,812,182 (-)EnsemblGRCm38mm10GRCm38
MGSCv371844,584,714 - 44,971,836 (-)NCBIGRCm37mm9NCBIm37
MGSCv361844,550,392 - 44,555,234 (-)NCBImm8
Celera1845,807,563 - 46,200,023 (-)NCBICelera
Cytogenetic Map18B3NCBI
cM Map1823.74NCBI
Mcc
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540832,928,519 - 33,264,727 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540832,928,519 - 33,265,049 (-)NCBIChiLan1.0ChiLan1.0
MCC
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.15114,184,907 - 114,457,400 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5114,184,907 - 114,647,847 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v05108,382,066 - 108,845,503 (-)NCBIMhudiblu_PPA_v0panPan3
MCC
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1435,291,297 - 35,592,388 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl435,312,814 - 35,592,282 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha435,258,841 - 35,559,927 (-)NCBI
ROS_Cfam_1.0435,656,537 - 35,958,139 (-)NCBI
UMICH_Zoey_3.1435,480,416 - 35,784,856 (-)NCBI
UNSW_CanFamBas_1.0435,668,029 - 35,970,362 (-)NCBI
UU_Cfam_GSD_1.0436,176,583 - 36,478,012 (-)NCBI
Mcc
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213125,905,158 - 126,351,432 (-)NCBI
SpeTri2.0NW_0049365974,930,065 - 5,191,311 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MCC
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2116,287,198 - 116,741,955 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12116,286,353 - 116,748,620 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22121,307,432 - 121,321,926 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MCC
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12316,309,574 - 16,773,736 (-)NCBI
ChlSab1.1 Ensembl2316,310,968 - 16,579,343 (-)Ensembl
Vero_WHO_p1.0NW_02366603461,661,123 - 62,145,017 (+)NCBI
Mcc
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247338,607,645 - 9,035,484 (+)NCBI

Position Markers
D18Chm48  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_5.0113,805,931 - 13,806,114NCBIRnor5.0
Rnor_5.0113,569,503 - 13,569,686NCBIRnor5.0
Rnor_5.0X87,473,210 - 87,473,393NCBIRnor5.0
Rnor_5.0X87,467,408 - 87,467,591NCBIRnor5.0
RGSC_v3.41838,369,050 - 38,369,232UniSTSRGSC3.4
Cytogenetic Map18q11UniSTS
Tceb1l-rs1  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_5.01835,610,106 - 35,610,325NCBIRnor5.0
Rnor_5.01835,405,109 - 35,405,328NCBIRnor5.0
Rnor_5.01037,382,354 - 37,382,565NCBIRnor5.0
RGSC_v3.41037,679,722 - 37,679,932UniSTSRGSC3.4
RGSC_v3.41838,158,463 - 38,158,681UniSTSRGSC3.4
Celera1035,770,882 - 35,771,092UniSTS
Cytogenetic Map18q11UniSTS
Cytogenetic Map10q22UniSTS
RH144300  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21837,231,506 - 37,231,808 (-)MAPPER
Rnor_6.0112,028,319 - 12,028,620NCBIRnor6.0
Rnor_5.0113,618,193 - 13,618,494UniSTSRnor5.0
RGSC_v3.41838,552,331 - 38,552,632UniSTSRGSC3.4
Cytogenetic Map18q11UniSTS
BF390789  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21837,180,184 - 37,180,347 (-)MAPPER
Rnor_6.0112,089,076 - 12,089,238NCBIRnor6.0
Rnor_5.0113,677,423 - 13,677,585UniSTSRnor5.0
RGSC_v3.41838,497,248 - 38,497,410UniSTSRGSC3.4
Cytogenetic Map18q11UniSTS
AU049155  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21836,953,376 - 36,953,669 (-)MAPPER
Rnor_6.0112,337,447 - 12,337,741NCBIRnor6.0
Rnor_6.01564,575,723 - 64,576,017NCBIRnor6.0
Rnor_5.01568,208,757 - 68,209,051UniSTSRnor5.0
Rnor_5.0113,923,668 - 13,923,962UniSTSRnor5.0
RGSC_v3.41838,264,260 - 38,264,554UniSTSRGSC3.4
Cytogenetic Map18q11UniSTS
fc33h10.x1  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_5.01838,043,730 - 38,044,631NCBIRnor5.0
Rnor_5.01838,043,730 - 38,044,623NCBIRnor5.0
Rnor_5.01835,481,779 - 35,482,680NCBIRnor5.0
Rnor_5.0113,954,405 - 13,955,298NCBIRnor5.0
Rnor_5.0113,954,397 - 13,955,298NCBIRnor5.0
Rnor_5.01835,481,779 - 35,482,672NCBIRnor5.0
RGSC_v3.41838,228,930 - 38,229,830UniSTSRGSC3.4
RGSC_v3.41838,228,930 - 38,229,822UniSTSRGSC3.4
Cytogenetic Map18q11UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354647Despr8Despair related QTL 80.0000341locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)1124368159Rat
2298546Neuinf4Neuroinflammation QTL 45.1nervous system integrity trait (VT:0010566)spinal cord RT1-B protein level (CMO:0002132)1128468970Rat
2313053Bss51Bone structure and strength QTL 513.80.0001tibia length (VT:0004357)tibia length (CMO:0000450)1134993530Rat
2313070Bss52Bone structure and strength QTL 524.40.0001body length (VT:0001256)body length (CMO:0000013)1134993530Rat
2313090Bmd69Bone mineral density QTL 694.40.0001tibia mineral mass (VT:1000283)cortical volumetric bone mineral density (CMO:0001730)1134993530Rat
738020Pia8Pristane induced arthritis QTL 84.7joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1164407321Rat
1578650Bmd6Bone mineral density QTL 612.2femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)125439343579402Rat
1578651Bmd7Bone mineral density QTL 714.2femur mineral mass (VT:0010011)cortical volumetric bone mineral density (CMO:0001730)125439343579402Rat
1578669Bss9Bone structure and strength QTL 96.3femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)125439343579402Rat
1554320Bmd1Bone mineral density QTL 112.20.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)125439386904217Rat
1600360Mcs16Mammary carcinoma susceptibility QTL 162.4mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)1186804543724576Rat
7421626Bp360Blood pressure QTL 3600.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1457869349578693Rat
631688Hcas2Hepatocarcinoma susceptibility QTL 230.0001liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)15655769122614963Rat
4889451Eae29Experimental allergic encephalomyelitis QTL 295.51nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)1565577285706974Rat
1300167Hrtrt2Heart rate QTL 24.35heart pumping trait (VT:2000009)heart rate (CMO:0000002)11131448975844121Rat
2313062Bmd73Bone mineral density QTL 733.90.0001tibia mineral mass (VT:1000283)cortical volumetric bone mineral density (CMO:0001730)11131448983657083Rat
2313065Bss67Bone structure and strength QTL 673.10.0001tibia area (VT:1000281)tibia total energy absorbed before break (CMO:0001736)11131448983657083Rat
2313069Bss68Bone structure and strength QTL 682.90.0001tibia size trait (VT:0100001)tibia total energy absorbed before break (CMO:0001736)11131448983657083Rat
2313075Bss66Bone structure and strength QTL 663.40.0001tibia length (VT:0004357)tibia length (CMO:0000450)11131448983657083Rat
2313077Bss69Bone structure and strength QTL 693.50.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)11131448983657083Rat
2313092Bmd72Bone mineral density QTL 722.50.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)11131448983657083Rat
2313097Bss70Bone structure and strength QTL 703.50.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)11131448983657083Rat
2317755Glom22Glomerulus QTL 223.8urine protein amount (VT:0005160)urine protein level (CMO:0000591)11131465834993348Rat
2300180Bmd67Bone mineral density QTL 674.80.0001femur mineral mass (VT:0010011)bone mineral density (CMO:0001226)18138195967Rat
2293661Bss50Bone structure and strength QTL 504.640.0003lumbar vertebra size trait (VT:0010518)lumbar vertebra trabecular cross-sectional area (CMO:0001692)18138195967Rat
9589153Insul31Insulin level QTL 317.150.05blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)18138753381Rat
2299160Iddm35Insulin dependent diabetes mellitus QTL 352.79blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)18440751362570466Rat
2312568Glom21Glomerulus QTL 2120.005kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)18543013441781619Rat
2313082Bss85Bone structure and strength QTL 850.80.0001long bone metaphysis morphology trait (VT:0000133)tibia midshaft total cross-sectional area (CMO:0001715)181467885259678852Rat
1331753Bp231Blood pressure QTL 2313.643arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)181553942753861431Rat
1358358Sradr6Stress Responsive Adrenal Weight QTL 62.49adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)181553942761499684Rat
6903359Bp355Blood pressure QTL 3553.6arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)181553967161985648Rat
2293708Bss46Bone structure and strength QTL 468.80.0001lumbar vertebra morphology trait (VT:0010494)lumbar vertebra cortical cross-sectional area (CMO:0001690)181569587268524999Rat
1578661Bss20Bone structure and strength QTL 203.7femur morphology trait (VT:0000559)femoral neck cross-sectional area (CMO:0001697)181569587287080053Rat
1578667Bss21Bone structure and strength QTL 213.5femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)181569587287080053Rat
1358193Emca2Estrogen-induced mammary cancer QTL 21.6mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)181903103068436105Rat
1600373Mamtr6Mammary tumor resistance QTL 6mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)182028575887080053Rat
7387267Uae42Urinary albumin excretion QTL 420.61urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)142163949166639491Rat
1331741Bp232Blood pressure QTL 2323.59112arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)182260373687074531Rat
6903353Bp353Blood pressure QTL 3532.8arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)182260476461985648Rat
1641923Colcr8Colorectal carcinoma resistance QTL 83.10.0014intestine integrity trait (VT:0010554)poorly differentiated malignant colorectal tumor number (CMO:0002076)182318422753861431Rat
1331733Bp233Blood pressure QTL 2333.97196arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)182596102681761656Rat
2325839Bp348Blood pressure QTL 3480.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)182674340443659626Rat
2301413Bp318Blood pressure QTL 3180.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)182774302448499517Rat
12904673Cm127Cardiac mass QTL 1270.005heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)182774302448499517Rat
12904675Am19Aortic mass QTL 190.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)182774302448499517Rat
12904677Kidm72Kidney mass QTL 720.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)182774302448499517Rat
12904668Bw188Body weight QTL 1880.03body mass (VT:0001259)body weight (CMO:0000012)182774302448499517Rat
12904669Cm125Cardiac mass QTL 1250.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)182774302448499517Rat
12904670Cm126Cardiac mass QTL 1260.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)182774302448499517Rat
2300157Bmd66Bone mineral density QTL 6613.10.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)183053361475533614Rat
2300177Bmd65Bone mineral density QTL 6519.70.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)183053361475533614Rat
2293704Bss35Bone structure and strength QTL 354.590.0002femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)183053361475533614Rat
9590318Scort22Serum corticosterone level QTL 227.640.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)183136134176361341Rat
1331754Bp230Blood pressure QTL 2304.61609arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183136134176361341Rat
9589816Gluco68Glucose level QTL 687.250.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)183136134176361341Rat
8694378Bw157Body weight QTL 1573.590.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)183136134176361341Rat
738005Anxrr11Anxiety related response QTL 113.4exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)183160842476608424Rat
61383Bp47Blood pressure QTL 4717.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)183172837362570429Rat
1331776Bp225Blood pressure QTL 2252.829arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)183267035261985812Rat
1331774Bp226Blood pressure QTL 2264.41065arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183267035261985812Rat
1331742Bp228Blood pressure QTL 2283.88752arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183267035261985812Rat
1331798Bp224Blood pressure QTL 2243.53873arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183267035261985812Rat
1331727Bp237Blood pressure QTL 2373.053arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183267035263897621Rat
61429Cia17Collagen induced arthritis QTL 174.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)183267035273016546Rat
2303120Mamtr8Mammary tumor resistance QTL 80.001mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)183267035287080053Rat
6903347Bp350Blood pressure QTL 3504.4arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183267047361985648Rat
631274Sprol1Serum protein level QTL 15.3blood total protein amount (VT:0005567)serum total protein level (CMO:0000661)183270402280696226Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:205
Count of miRNA genes:143
Interacting mature miRNAs:158
Transcripts:ENSRNOT00000015172
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 30 20 14 6 14 3 23 30 11
Low 3 12 37 27 13 27 8 10 71 12 7 8
Below cutoff 1 1 4

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000015172   ⟹   ENSRNOP00000015172
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1835,683,185 - 35,817,117 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000079667   ⟹   ENSRNOP00000073806
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1835,683,501 - 35,780,519 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000085714   ⟹   ENSRNOP00000071358
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1835,683,185 - 35,817,127 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000093439   ⟹   ENSRNOP00000076146
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl112,006,660 - 12,128,845 (+)Ensembl
RefSeq Acc Id: NM_001170534   ⟹   NP_001164005
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21836,798,372 - 37,255,038 (-)NCBI
Rnor_6.0112,006,663 - 12,128,849 (+)NCBI
Rnor_6.01835,683,185 - 35,817,117 (-)NCBI
Rnor_5.01835,348,808 - 35,484,229 (-)NCBI
Rnor_5.0113,595,971 - 13,952,963 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039096841   ⟹   XP_038952769
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21836,794,206 - 37,266,206 (-)NCBI
RefSeq Acc Id: XM_039096842   ⟹   XP_038952770
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21836,794,206 - 37,266,237 (-)NCBI
RefSeq Acc Id: XM_039096843   ⟹   XP_038952771
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21836,794,206 - 37,266,206 (-)NCBI
RefSeq Acc Id: XM_039096844   ⟹   XP_038952772
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21836,794,206 - 37,266,192 (-)NCBI
RefSeq Acc Id: XM_039096845   ⟹   XP_038952773
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21836,794,206 - 37,266,228 (-)NCBI
RefSeq Acc Id: XM_039096846   ⟹   XP_038952774
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21836,794,206 - 37,073,364 (-)NCBI
RefSeq Acc Id: XM_039096847   ⟹   XP_038952775
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21836,794,206 - 36,957,781 (-)NCBI
RefSeq Acc Id: XM_039096848   ⟹   XP_038952776
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21836,794,206 - 36,976,589 (-)NCBI
RefSeq Acc Id: XM_039096849   ⟹   XP_038952777
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21836,794,206 - 36,954,765 (-)NCBI
Reference Sequences
RefSeq Acc Id: NP_001164005   ⟸   NM_001170534
- Sequence:
RefSeq Acc Id: ENSRNOP00000073806   ⟸   ENSRNOT00000079667
RefSeq Acc Id: ENSRNOP00000076146   ⟸   ENSRNOT00000093439
RefSeq Acc Id: ENSRNOP00000071358   ⟸   ENSRNOT00000085714
RefSeq Acc Id: ENSRNOP00000015172   ⟸   ENSRNOT00000015172
RefSeq Acc Id: XP_038952770   ⟸   XM_039096842
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038952773   ⟸   XM_039096845
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038952771   ⟸   XM_039096843
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038952769   ⟸   XM_039096841
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038952772   ⟸   XM_039096844
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038952774   ⟸   XM_039096846
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038952776   ⟸   XM_039096848
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038952775   ⟸   XM_039096847
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038952777   ⟸   XM_039096849
- Peptide Label: isoform X6
Protein Domains
EF-hand   MCC-bdg_PDZ

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1561988 AgrOrtholog
Ensembl Genes ENSRNOG00000011271 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOG00000062232 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000015172 UniProtKB/TrEMBL
  ENSRNOP00000071358 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOP00000073806 UniProtKB/TrEMBL
  ENSRNOP00000076146 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000015172 UniProtKB/TrEMBL
  ENSRNOT00000079667 UniProtKB/TrEMBL
  ENSRNOT00000085714 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOT00000093439 ENTREZGENE, UniProtKB/TrEMBL
InterPro EF-hand-dom_pair UniProtKB/TrEMBL
  EF_Hand_1_Ca_BS UniProtKB/TrEMBL
  EF_hand_dom UniProtKB/TrEMBL
  USBP1-like UniProtKB/TrEMBL
  USH1C-bd_PDZ_domain UniProtKB/TrEMBL
NCBI Gene 307449 ENTREZGENE
PANTHER PTHR23347 UniProtKB/TrEMBL
Pfam EF-hand_7 UniProtKB/TrEMBL
  MCC-bdg_PDZ UniProtKB/TrEMBL
PhenoGen Mcc PhenoGen
PROSITE EF_HAND_1 UniProtKB/TrEMBL
  EF_HAND_2 UniProtKB/TrEMBL
SMART EFh UniProtKB/TrEMBL
Superfamily-SCOP SSF47473 UniProtKB/TrEMBL
UniProt A0A0G2K098_RAT UniProtKB/TrEMBL
  A0A0G2K6G7_RAT UniProtKB/TrEMBL
  A0A1W2Q665_RAT UniProtKB/TrEMBL
  F1LZS6_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Mcc  MCC regulator of WNT signaling pathway  LOC100909795  colorectal mutant cancer protein-like  Data Merged 737654 PROVISIONAL
2019-04-10 Mcc  MCC regulator of WNT signaling pathway  Mcc  MCC, WNT signaling pathway regulator  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2018-05-18 Mcc  MCC, WNT signaling pathway regulator  Mcc  mutated in colorectal cancers  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-07-05 LOC100909795  colorectal mutant cancer protein-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2009-06-22 Mcc  mutated in colorectal cancers  RGD1561988  similar to Colorectal mutant cancer protein (MCC protein)   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2009-06-15 RGD1561988  similar to Colorectal mutant cancer protein (MCC protein)   Mcc_mapped  mutated in colorectal cancers (mapped)  Data Merged 1643240 APPROVED
2008-04-30 RGD1561988  similar to Colorectal mutant cancer protein (MCC protein)   RGD1561988_predicted  similar to Colorectal mutant cancer protein (MCC protein) (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1561988_predicted  similar to Colorectal mutant cancer protein (MCC protein) (predicted)  LOC307449  similar to Colorectal mutant cancer protein (MCC protein)  Symbol and Name status set to approved 1299863 APPROVED
2005-11-17 Mcc_mapped  mutated in colorectal cancers (mapped)  Mcc  mutated in colorectal cancers  Symbol and Name updated 1556543 APPROVED