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Gene: Mcc (MCC regulator of WNT signaling pathway) Rattus norvegicus
Symbol: Mcc
Name: MCC regulator of WNT signaling pathway
Description: Predicted to have calcium ion binding activity. Predicted to be involved in several processes, including negative regulation of canonical Wnt signaling pathway; negative regulation of epithelial cell migration; and negative regulation of epithelial cell proliferation. Predicted to localize to several cellular components, including the cytoplasmic ribonucleoprotein granule; cytosol; and nucleoplasm. Orthologous to human MCC (MCC regulator of WNT signaling pathway); INTERACTS WITH (+)-schisandrin B; 1,2-dimethylhydrazine; amphetamine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: LOC307449; MCC, WNT signaling pathway regulator; mutated in colorectal cancers; RGD1561988; similar to Colorectal mutant cancer protein (MCC protein)
Homo sapiens (human) : MCC (MCC regulator of WNT signaling pathway)  HGNC  Alliance
Sus scrofa (pig) : MCC (MCC regulator of WNT signaling pathway)
Chlorocebus sabaeus (African green monkey) : MCC (MCC regulator of WNT signaling pathway)
Heterocephalus glaber (naked mole-rat) : Mcc (MCC regulator of WNT signaling pathway)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: suggests misassembly; Annotation category: partial on reference assembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01835,683,185 - 35,817,117 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0112,006,663 - 12,128,849 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl112,006,660 - 12,128,845 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl1835,683,185 - 35,817,127 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01835,348,808 - 35,484,229 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.0113,595,971 - 13,952,963 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41838,099,803 - 38,576,214NCBIRGSC3.4rn4RGSC3.4
Cytogenetic Map18p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Mcc
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1561988
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2020-03-04
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.