Spink5 (serine peptidase inhibitor, Kazal type 5) - Rat Genome Database

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Gene: Spink5 (serine peptidase inhibitor, Kazal type 5) Rattus norvegicus
Analyze
Symbol: Spink5
Name: serine peptidase inhibitor, Kazal type 5
RGD ID: 1306540
Description: Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to be involved in epidermal cell differentiation and negative regulation of antibacterial peptide production. Predicted to act upstream of or within negative regulation of proteolysis and regulation of cell adhesion. Predicted to be located in several cellular components, including endoplasmic reticulum membrane; epidermal lamellar body; and perinuclear region of cytoplasm. Human ortholog(s) of this gene implicated in Netherton syndrome. Orthologous to human SPINK5 (serine peptidase inhibitor Kazal type 5); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 3,7-dihydropurine-6-thione.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC100910851; LOC361319; serine protease inhibitor Kazal-type 5; serine protease inhibitor Kazal-type 5-like; serine protease inhibitor, Kazal type 5
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81836,515,347 - 36,584,038 (+)NCBIGRCr8
mRatBN7.21836,264,452 - 36,333,143 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1836,264,452 - 36,332,185 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1836,368,467 - 36,437,168 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01837,086,815 - 37,155,518 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01836,463,716 - 36,532,415 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01835,118,300 - 35,190,458 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1835,121,967 - 35,191,069 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl1229,267,916 - 229,343,584 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01834,787,562 - 34,856,081 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41837,563,911 - 37,631,579 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11837,599,079 - 37,648,851 (+)NCBI
Cytogenetic Map18q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Mutations in SPINK5, encoding a serine protease inhibitor, cause Netherton syndrome. Chavanas S, etal., Nat Genet. 2000 Jun;25(2):141-2.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:10419450   PMID:12915442   PMID:15466487   PMID:15675955   PMID:15680911   PMID:17012259   PMID:20179351   PMID:23376485  


Genomics

Comparative Map Data
Spink5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81836,515,347 - 36,584,038 (+)NCBIGRCr8
mRatBN7.21836,264,452 - 36,333,143 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1836,264,452 - 36,332,185 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1836,368,467 - 36,437,168 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01837,086,815 - 37,155,518 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01836,463,716 - 36,532,415 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01835,118,300 - 35,190,458 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1835,121,967 - 35,191,069 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl1229,267,916 - 229,343,584 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01834,787,562 - 34,856,081 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41837,563,911 - 37,631,579 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11837,599,079 - 37,648,851 (+)NCBI
Cytogenetic Map18q11NCBI
SPINK5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385148,063,980 - 148,137,382 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5148,025,683 - 148,137,382 (+)EnsemblGRCh38hg38GRCh38
GRCh375147,443,543 - 147,516,945 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365147,423,759 - 147,497,120 (+)NCBINCBI36Build 36hg18NCBI36
Build 345147,423,758 - 147,497,037NCBI
Celera5143,524,323 - 143,597,562 (+)NCBICelera
Cytogenetic Map5q32NCBI
HuRef5142,590,808 - 142,664,035 (+)NCBIHuRef
CHM1_15146,875,990 - 146,949,062 (+)NCBICHM1_1
T2T-CHM13v2.05148,599,687 - 148,673,088 (+)NCBIT2T-CHM13v2.0
Spink5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391844,092,612 - 44,155,554 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1844,096,302 - 44,155,568 (+)EnsemblGRCm39 Ensembl
GRCm381843,959,545 - 44,022,487 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1843,963,235 - 44,022,501 (+)EnsemblGRCm38mm10GRCm38
MGSCv371844,122,895 - 44,182,141 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361844,088,572 - 44,147,818 (+)NCBIMGSCv36mm8
Celera1845,339,414 - 45,398,624 (+)NCBICelera
Cytogenetic Map18B3NCBI
cM Map1823.74NCBI
Spink5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554156,118,616 - 6,186,632 (-)NCBIChiLan1.0ChiLan1.0
SPINK5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24143,191,450 - 143,382,914 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15141,330,972 - 141,522,438 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05143,387,981 - 143,578,839 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15149,507,003 - 149,587,249 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5149,506,367 - 149,590,930 (+)Ensemblpanpan1.1panPan2
SPINK5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1242,285,537 - 42,365,637 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl242,285,537 - 42,365,690 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha239,331,980 - 39,411,492 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0242,745,184 - 42,825,339 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl242,723,407 - 42,825,338 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1239,815,140 - 39,895,271 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0240,625,209 - 40,705,273 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0241,448,356 - 41,528,467 (+)NCBIUU_Cfam_GSD_1.0
Spink5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213145,079,694 - 145,182,465 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049365046,653,703 - 6,750,110 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SPINK5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2149,309,540 - 149,382,282 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12149,309,482 - 149,382,286 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22155,870,595 - 155,896,727 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SPINK5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12350,587,698 - 50,667,219 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2350,592,412 - 50,663,302 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603427,098,281 - 27,174,482 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Spink5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247747,489,687 - 7,576,088 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247747,469,195 - 7,579,603 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Spink5
272 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:208
Count of miRNA genes:87
Interacting mature miRNAs:99
Transcripts:ENSRNOT00000017522, ENSRNOT00000073717
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
9589153Insul31Insulin level QTL 317.150.05blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)18142547119Rat
2299160Iddm35Insulin dependent diabetes mellitus QTL 352.79blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)18420794160377792Rat
2312568Glom21Glomerulus QTL 2120.005kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)18518585840503530Rat
2293708Bss46Bone structure and strength QTL 468.80.0001lumbar vertebra morphology trait (VT:0010494)lumbar vertebra cortical cross-sectional area (CMO:0001690)181179151863636873Rat
1578661Bss20Bone structure and strength QTL 203.7femur morphology trait (VT:0000559)femoral neck cross-sectional area (CMO:0001697)181179151883218561Rat
1578667Bss21Bone structure and strength QTL 213.5femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)181179151883218561Rat
61375Bp41Blood pressure QTL 412.4blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)181194429941122201Rat
1331753Bp231Blood pressure QTL 2313.643arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)181194429952293055Rat
1358358Sradr6Stress Responsive Adrenal Weight QTL 62.49adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)181194429959330563Rat
6903359Bp355Blood pressure QTL 3553.6arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)181194454459796478Rat
2313082Bss85Bone structure and strength QTL 850.80.0001long bone metaphysis morphology trait (VT:0000133)tibia midshaft total cross-sectional area (CMO:0001715)181495133759951337Rat
1358193Emca2Estrogen-induced mammary cancer QTL 21.6mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)181800759963571040Rat
1600373Mamtr6Mammary tumor resistance QTL 6mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)181927890183218561Rat
1331741Bp232Blood pressure QTL 2323.59112arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)182137289383213037Rat
1641923Colcr8Colorectal carcinoma resistance QTL 83.10.0014intestine integrity trait (VT:0010554)poorly differentiated malignant colorectal tumor number (CMO:0002076)182206624252293055Rat
1331733Bp233Blood pressure QTL 2333.97196arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)182479697779788953Rat
2325839Bp348Blood pressure QTL 3480.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)182557098570570985Rat
12904673Cm127Cardiac mass QTL 1270.005heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)182654808246969551Rat
12904675Am19Aortic mass QTL 190.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)182654808246969551Rat
12904677Kidm72Kidney mass QTL 720.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)182654808246969551Rat
12904668Bw188Body weight QTL 1880.03body mass (VT:0001259)body weight (CMO:0000012)182654808246969551Rat
12904669Cm125Cardiac mass QTL 1250.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)182654808246969551Rat
12904670Cm126Cardiac mass QTL 1260.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)182654808246969551Rat
2301413Bp318Blood pressure QTL 3180.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)182654808246969551Rat
2293704Bss35Bone structure and strength QTL 354.590.0002femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)182896485373964853Rat
2300157Bmd66Bone mineral density QTL 6613.10.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)182896485373964853Rat
2300177Bmd65Bone mineral density QTL 6519.70.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)182896485373964853Rat
9589816Gluco68Glucose level QTL 687.250.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)182979296574792965Rat
8694378Bw157Body weight QTL 1573.590.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)182979296574792965Rat
9590318Scort22Serum corticosterone level QTL 227.640.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)182979296574792965Rat
1331754Bp230Blood pressure QTL 2304.61609arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)182979296574792965Rat
738005Anxrr11Anxiety related response QTL 113.4exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)183003981375039813Rat
61383Bp47Blood pressure QTL 4717.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)183127168160377755Rat
1331742Bp228Blood pressure QTL 2283.88752arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183135940859796643Rat
1331774Bp226Blood pressure QTL 2264.41065arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183135940859796643Rat
1331776Bp225Blood pressure QTL 2252.829arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)183135940859796643Rat
1331798Bp224Blood pressure QTL 2243.53873arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183135940859796643Rat
1331727Bp237Blood pressure QTL 2373.053arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183135940861698465Rat
61429Cia17Collagen induced arthritis QTL 174.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)183135940870263868Rat
2303120Mamtr8Mammary tumor resistance QTL 80.001mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)183135940883218561Rat
6903347Bp350Blood pressure QTL 3504.4arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183135953059796478Rat
631274Sprol1Serum protein level QTL 15.3blood total protein amount (VT:0005567)serum total protein level (CMO:0000661)183139332077209694Rat
631518Bw11Body weight QTL 112.8body mass (VT:0001259)body weight (CMO:0000012)183587072380870723Rat

Markers in Region
RH133717  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_5.01834,855,720 - 34,855,938NCBIRnor5.0
Rnor_5.0255,120,392 - 55,120,610NCBIRnor5.0
Rnor_5.01236,500,194 - 236,500,412NCBIRnor5.0
RGSC_v3.41837,632,179 - 37,632,396UniSTSRGSC3.4
Cytogenetic Map18q11UniSTS


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000017522   ⟹   ENSRNOP00000017522
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1836,264,452 - 36,332,185 (+)Ensembl
Rnor_6.0 Ensembl1835,121,967 - 35,189,644 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000073717   ⟹   ENSRNOP00000066620
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1229,267,916 - 229,343,054 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000076941   ⟹   ENSRNOP00000068512
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1229,267,944 - 229,342,240 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000078731   ⟹   ENSRNOP00000069499
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1835,136,132 - 35,191,069 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000082670   ⟹   ENSRNOP00000070505
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1229,267,926 - 229,343,584 (+)Ensembl
RefSeq Acc Id: NM_001170606   ⟹   NP_001164077
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81836,515,347 - 36,584,038 (+)NCBI
mRatBN7.21836,264,452 - 36,333,143 (+)NCBI
Rnor_6.01835,121,939 - 35,190,458 (+)NCBI
Rnor_5.01834,787,562 - 34,856,081 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001164077 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000017522
  ENSRNOP00000017522.6
Reference Protein Sequences
RefSeq Acc Id: NP_001164077   ⟸   NM_001170606
- Peptide Label: precursor
- UniProtKB: D3ZET2 (UniProtKB/TrEMBL),   A6KUC9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000070505   ⟸   ENSRNOT00000082670
RefSeq Acc Id: ENSRNOP00000017522   ⟸   ENSRNOT00000017522
RefSeq Acc Id: ENSRNOP00000066620   ⟸   ENSRNOT00000073717
RefSeq Acc Id: ENSRNOP00000068512   ⟸   ENSRNOT00000076941
RefSeq Acc Id: ENSRNOP00000069499   ⟸   ENSRNOT00000078731
Protein Domains
Kazal-like

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZET2-F1-model_v2 AlphaFold D3ZET2 1-1019 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1306540 AgrOrtholog
BioCyc Gene G2FUF-7671 BioCyc
Ensembl Genes ENSRNOG00000013116 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOG00000048953 Ensembl
Ensembl Transcript ENSRNOT00000017522 ENTREZGENE
  ENSRNOT00000017522.9 UniProtKB/TrEMBL
Gene3D-CATH 3.30.60.30 UniProtKB/TrEMBL
InterPro Kazal_dom_sf UniProtKB/TrEMBL
  Prot_inh_Kazal UniProtKB/TrEMBL
KEGG Report rno:361319 UniProtKB/TrEMBL
NCBI Gene 361319 ENTREZGENE
PANTHER SERINE PROTEASE INHIBITOR KAZAL-TYPE 7 SPINK7 UniProtKB/TrEMBL
  SERINE PROTEASE INHIBITOR KAZAL-TYPE 9 UniProtKB/TrEMBL
Pfam Kazal_1 UniProtKB/TrEMBL
  Kazal_2 UniProtKB/TrEMBL
PhenoGen Spink5 PhenoGen
PROSITE KAZAL UniProtKB/TrEMBL
  KAZAL_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000013116 RatGTEx
  ENSRNOG00000048953 RatGTEx
SMART KAZAL UniProtKB/TrEMBL
Superfamily-SCOP SSF100895 UniProtKB/TrEMBL
UniProt A6KUC9 ENTREZGENE, UniProtKB/TrEMBL
  D3ZET2 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Spink5  serine peptidase inhibitor, Kazal type 5  LOC100910851  serine protease inhibitor Kazal-type 5-like  Data merged from RGD:6496266 737654 PROVISIONAL
2012-07-05 LOC100910851  serine protease inhibitor Kazal-type 5-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-03-07 Spink5  serine peptidase inhibitor, Kazal type 5  Spink5_predicted  serine protease inhibitor, Kazal type 5 (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-12 Spink5_predicted  serine protease inhibitor, Kazal type 5 (predicted)      Symbol and Name status set to approved 70820 APPROVED