Stk32a (serine/threonine kinase 32A)

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Gene: Stk32a (serine/threonine kinase 32A) Rattus norvegicus

Analyze

Symbol:

Stk32a

Name:

serine/threonine kinase 32A

RGD ID:

1308338

Description:

Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in intracellular signal transduction and peptidyl-serine phosphorylation. Orthologous to human STK32A (serine/threonine kinase 32A); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; bisphenol A.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

LOC364858; serine/threonine-protein kinase 32A

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	STK32A (serine/threonine kinase 32A)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Stk32a (serine/threonine kinase 32A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Stk32a (serine/threonine kinase 32A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	STK32A (serine/threonine kinase 32A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	STK32A (serine/threonine kinase 32A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Stk32a (serine/threonine kinase 32A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	STK32A (serine/threonine kinase 32A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	STK32A (serine/threonine kinase 32A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Stk32a (serine/threonine kinase 32A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	STK32C (serine/threonine kinase 32C)	HGNC	OrthoDB
Homo sapiens (human):	STK32B (serine/threonine kinase 32B)	HGNC	OrthoDB
Alliance orthologs ³
Homo sapiens (human):	STK32A (serine/threonine kinase 32A)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Stk32a (serine/threonine kinase 32A)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	stk32a (serine/threonine kinase 32A)	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoInspector\|SonicParanoid)
Caenorhabditis elegans (roundworm):	M03C11.1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG32944	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	18	35,258,865 - 35,374,985 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	18	35,259,052 - 35,369,451 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	18	35,363,088 - 35,472,487 (+)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	18	36,081,399 - 36,190,804 (+)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	18	35,458,355 - 35,567,752 (+)	NCBI	Rnor_WKY
Rnor_6.0	18	37,597,305 - 37,706,884 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	18	37,597,156 - 37,710,306 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	18	37,253,122 - 37,366,281 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	18	36,501,876 - 36,611,248 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	18	36,537,033 - 36,646,846 (+)	NCBI
Celera	18	34,848,008 - 34,957,385 (+)	NCBI		Celera
Cytogenetic Map	18	p11	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

familial adenomatous polyposis 1 (ISO)

Hereditary Neoplastic Syndromes (ISO)

Neurodevelopmental Disorders (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dichloroethane (ISO)

1,2-dimethylhydrazine (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,3,7,8-Tetrachlorodibenzofuran (EXP)

4,4'-sulfonyldiphenol (ISO)

acrylamide (ISO)

belinostat (ISO)

benzo[a]pyrene (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP)

C60 fullerene (EXP)

cis-caffeic acid (ISO)

copper atom (ISO)

copper(0) (ISO)

cyclosporin A (ISO)

dorsomorphin (ISO)

entinostat (ISO)

ethanol (ISO)

folic acid (ISO)

GW 4064 (ISO)

mercury dibromide (ISO)

methylmercury chloride (ISO)

N-Nitrosopyrrolidine (ISO)

nickel atom (ISO)

p-chloromercuribenzoic acid (ISO)

panobinostat (ISO)

paracetamol (ISO)

perfluorononanoic acid (ISO)

phenylmercury acetate (ISO)

SB 431542 (ISO)

sodium arsenite (ISO)

thapsigargin (ISO)

titanium dioxide (ISO)

trans-caffeic acid (ISO)

trichostatin A (ISO)

troglitazone (ISO)

valproic acid (ISO)

vinclozolin (EXP)

vorinostat (ISO)

zoledronic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

intracellular signal transduction (IBA)

peptidyl-serine phosphorylation (IBA)

Molecular Function

ATP binding (IEA)

protein binding (ISO)

protein serine/threonine kinase activity (IBA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	GOA pipeline	RGD automated data pipeline
3.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data

Stk32a
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	18	35,258,865 - 35,374,985 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	18	35,259,052 - 35,369,451 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	18	35,363,088 - 35,472,487 (+)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	18	36,081,399 - 36,190,804 (+)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	18	35,458,355 - 35,567,752 (+)	NCBI	Rnor_WKY
Rnor_6.0	18	37,597,305 - 37,706,884 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	18	37,597,156 - 37,710,306 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	18	37,253,122 - 37,366,281 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	18	36,501,876 - 36,611,248 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	18	36,537,033 - 36,646,846 (+)	NCBI
Celera	18	34,848,008 - 34,957,385 (+)	NCBI		Celera
Cytogenetic Map	18	p11	NCBI

STK32A
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	5	147,235,026 - 147,401,990 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p13 Ensembl	5	147,234,963 - 147,387,855 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	5	146,614,589 - 146,767,418 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	5	146,594,862 - 146,708,586 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	5	146,594,861 - 146,708,581	NCBI
Celera	5	142,696,707 - 142,845,791 (+)	NCBI		Celera
Cytogenetic Map	5	q32	NCBI
HuRef	5	141,761,757 - 141,910,943 (+)	NCBI		HuRef
CHM1_1	5	146,046,999 - 146,196,079 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	5	147,770,995 - 147,923,633 (+)	NCBI		T2T-CHM13v2.0

Stk32a
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	18	43,340,762 - 43,450,546 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	18	43,340,648 - 43,451,747 (+)	Ensembl		GRCm39 Ensembl
GRCm38	18	43,207,697 - 43,317,481 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	18	43,207,583 - 43,318,682 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	18	43,367,351 - 43,477,135 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	18	43,333,028 - 43,442,812 (+)	NCBI		MGSCv36	mm8
Celera	18	44,582,297 - 44,700,893 (+)	NCBI		Celera
Cytogenetic Map	18	B3	NCBI

Stk32a
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955415	6,815,852 - 6,948,232 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955415	6,817,152 - 6,948,180 (-)	NCBI	ChiLan1.0	ChiLan1.0

STK32A
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	5	148,694,879 - 148,848,227 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	5	148,694,879 - 148,844,508 (+)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	5	142,683,261 - 142,868,491 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3

STK32A
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	2	41,555,314 - 41,686,016 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	2	41,559,019 - 41,683,496 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	2	38,597,167 - 38,727,788 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	2	42,010,369 - 42,141,271 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	2	42,010,123 - 42,138,189 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	2	39,086,862 - 39,217,202 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	2	39,893,973 - 40,027,318 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	2	40,718,283 - 40,849,352 (+)	NCBI		UU_Cfam_GSD_1.0

Stk32a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	145,797,205 - 145,936,117 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936504	7,370,332 - 7,510,562 (-)	Ensembl	SpeTri2.0
SpeTri2.0	NW_004936504	7,369,180 - 7,510,016 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

STK32A
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	148,519,679 - 148,659,461 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	2	148,519,808 - 148,663,591 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	155,283,793 - 155,320,647 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

STK32A
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	23	49,786,215 - 49,935,407 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	23	49,786,283 - 49,939,332 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666034	27,827,660 - 27,980,790 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Stk32a
(Heterocephalus glaber - naked mole-rat)

Naked Mole-rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624774	6,703,443 - 6,834,553 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624774	6,703,983 - 6,833,226 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Stk32a
529 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	42
Count of miRNA genes:	39
Interacting mature miRNAs:	42
Transcripts:	ENSRNOT00000031370
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
61388	Bp2	Blood pressure QTL 2	3.23		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	18	1	35374722	Rat
9589153	Insul31	Insulin level QTL 31	7.15	0.05	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	18	1	42547119	Rat
2299160	Iddm35	Insulin dependent diabetes mellitus QTL 35	2.79		blood glucose amount (VT:0000188)	age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)	18	4207941	60377792	Rat
2312568	Glom21	Glomerulus QTL 21	2	0.005	kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	18	5185858	40503530	Rat
2293708	Bss46	Bone structure and strength QTL 46	8.8	0.0001	lumbar vertebra morphology trait (VT:0010494)	lumbar vertebra cortical cross-sectional area (CMO:0001690)	18	11791518	63636873	Rat
1578661	Bss20	Bone structure and strength QTL 20	3.7		femur morphology trait (VT:0000559)	femoral neck cross-sectional area (CMO:0001697)	18	11791518	83218561	Rat
1578667	Bss21	Bone structure and strength QTL 21	3.5		femur morphology trait (VT:0000559)	femoral neck cortical cross-sectional area (CMO:0001702)	18	11791518	83218561	Rat
61375	Bp41	Blood pressure QTL 41	2.4		blood pressure trait (VT:0000183)	systolic blood pressure (CMO:0000004)	18	11944299	41122201	Rat
1331753	Bp231	Blood pressure QTL 231	3.643		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	18	11944299	52293055	Rat
1358358	Sradr6	Stress Responsive Adrenal Weight QTL 6	2.49		adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	18	11944299	59330563	Rat
6903359	Bp355	Blood pressure QTL 355	3.6		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	18	11944544	59796478	Rat
2313082	Bss85	Bone structure and strength QTL 85	0.8	0.0001	long bone metaphysis morphology trait (VT:0000133)	tibia midshaft total cross-sectional area (CMO:0001715)	18	14951337	59951337	Rat
1358193	Emca2	Estrogen-induced mammary cancer QTL 2	1.6		mammary gland integrity trait (VT:0010552)	post-insult time to mammary tumor formation (CMO:0000345)	18	18007599	63571040	Rat
1600373	Mamtr6	Mammary tumor resistance QTL 6			mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	18	19278901	83218561	Rat
1331741	Bp232	Blood pressure QTL 232	3.59112		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	18	21372893	83213037	Rat
1641923	Colcr8	Colorectal carcinoma resistance QTL 8	3.1	0.0014	intestine integrity trait (VT:0010554)	poorly differentiated malignant colorectal tumor number (CMO:0002076)	18	22066242	52293055	Rat
1331733	Bp233	Blood pressure QTL 233	3.97196		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	24796977	79788953	Rat
2325839	Bp348	Blood pressure QTL 348		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	25570985	70570985	Rat
12904673	Cm127	Cardiac mass QTL 127		0.005	heart right ventricle mass (VT:0007033)	heart right ventricle weight to body weight ratio (CMO:0000914)	18	26548082	46969551	Rat
12904675	Am19	Aortic mass QTL 19		0.001	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	18	26548082	46969551	Rat
12904677	Kidm72	Kidney mass QTL 72		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	18	26548082	46969551	Rat
12904668	Bw188	Body weight QTL 188		0.03	body mass (VT:0001259)	body weight (CMO:0000012)	18	26548082	46969551	Rat
12904669	Cm125	Cardiac mass QTL 125		0.001	heart mass (VT:0007028)	heart wet weight to body weight ratio (CMO:0002408)	18	26548082	46969551	Rat
12904670	Cm126	Cardiac mass QTL 126		0.001	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	18	26548082	46969551	Rat
2301413	Bp318	Blood pressure QTL 318		0.002	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	26548082	46969551	Rat
2293704	Bss35	Bone structure and strength QTL 35	4.59	0.0002	femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	18	28964853	73964853	Rat
2300157	Bmd66	Bone mineral density QTL 66	13.1	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	18	28964853	73964853	Rat
2300177	Bmd65	Bone mineral density QTL 65	19.7	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	18	28964853	73964853	Rat
9589816	Gluco68	Glucose level QTL 68	7.25	0.001	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	18	29792965	74792965	Rat
8694378	Bw157	Body weight QTL 157	3.59	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	18	29792965	74792965	Rat
9590318	Scort22	Serum corticosterone level QTL 22	7.64	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	18	29792965	74792965	Rat
1331754	Bp230	Blood pressure QTL 230	4.61609		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	29792965	74792965	Rat
738005	Anxrr11	Anxiety related response QTL 11	3.4		exploratory behavior trait (VT:0010471)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	18	30039813	75039813	Rat
61383	Bp47	Blood pressure QTL 47	17.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	18	31271681	60377755	Rat
1331742	Bp228	Blood pressure QTL 228	3.88752		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	31359408	59796643	Rat
1331774	Bp226	Blood pressure QTL 226	4.41065		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	31359408	59796643	Rat
1331776	Bp225	Blood pressure QTL 225	2.829		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	18	31359408	59796643	Rat
1331798	Bp224	Blood pressure QTL 224	3.53873		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	31359408	59796643	Rat
1331727	Bp237	Blood pressure QTL 237	3.053		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	31359408	61698465	Rat
61429	Cia17	Collagen induced arthritis QTL 17	4.6		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	18	31359408	70263868	Rat
2303120	Mamtr8	Mammary tumor resistance QTL 8		0.001	mammary gland integrity trait (VT:0010552)	mammary tumor growth rate (CMO:0000344)	18	31359408	83218561	Rat
6903347	Bp350	Blood pressure QTL 350	4.4		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	31359530	59796478	Rat
631274	Sprol1	Serum protein level QTL 1	5.3		blood total protein amount (VT:0005567)	serum total protein level (CMO:0000661)	18	31393320	77209694	Rat

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium									2
Low	2	1	16		18		8	10	50	29	17	11	8
Below cutoff	1	22	13	13	1	13		1	18	6	19

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001191894	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039097002	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH473974	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000299	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000031370 ⟹ ENSRNOP00000036737

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	18	35,259,052 - 35,369,451 (+)	Ensembl
Rnor_6.0 Ensembl	18	37,597,156 - 37,710,306 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000115603 ⟹ ENSRNOP00000079735

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	18	35,259,052 - 35,369,451 (+)	Ensembl

RefSeq Acc Id:

NM_001191894 ⟹ NP_001178823

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	18	35,259,052 - 35,368,451 (+)	NCBI
Rnor_6.0	18	37,597,305 - 37,706,884 (+)	NCBI
Rnor_5.0	18	37,253,122 - 37,366,281 (+)	NCBI
Celera	18	34,848,008 - 34,957,385 (+)	NCBI

Sequence:

show sequence

AGCGGCAGGTGCCTGAGCCCAGCGAGCAGTCCTGCCAGGGCCATTCCCTCAACCGCGTCCTGAT
CCGCAGGTGTCTTCTGTATCTGTCTTTCCTGGCCTGCTGAGTTCTGTCAGCCTCTGCTCCTCGA
ATGGAAACATCATCCTGAGGTATCCAGCCAATTTTTTGGGGCCTACATTAAACAAAGATGAGTG
CTTCTTCCAGGATACTTTAACTAGAGTGTCCAGGTCAGTTCAAACTTGACCATGGGAGCCAACA
CTTCAAGCAAAGCACCAGTGCTTGATGAAAATGAAGACGTCAACTTTGACCACTTTGAAATTTT
GCGAGCCATTGGGAAGGGCAGTTTTGGGAAGGTCTGCATTGTGCAGAAGAATGATACCAAGAAG
ATGTACGCCATGAAGTACATGAATAAACAGAAGTGTGTGGAGCGGAATGAAGTGAGGAATGTCT
TCAAAGAACTCCAGATCATGCAGGGCCTAGAACACCCTTTCCTGGTGAATCTGTGGTATTCCTT
CCAAGATGAAGAAGACATGTTCATGGTGGTGGACCTGCTACTTGGTGGGGACCTGCGTTATCAC
CTGCAGCAGAATGTCCACTTCCAGGAGGACACAGTGAAGCTCTTCATCTGTGAGCTGGCCATGG
CCCTGGACTATCTGCAGAGCCAGCGCATCATTCACAGGGATATGAAACCAGACAATATTTTACT
TGATGAACATGGGCATGTGCACATCACAGACTTCAACATTGCTGCCATGCTGCCCAAGGAGACT
AGGATCACCACCGTAGCTGGCACCAAGCCCTACATGGCACCCGAGATGTTCAGCTCTAGGAAGG
AATCGGGTTACTCCTTCGCTGTTGACTGGTGGTCCCTCGGGGTGACGGCTTATGAACTGCTGAG
AGGCCGGAGGCCATATCACATCCGCTCCAGTACTTCCAGCAAGGAAATTGTCAACATGTTTGAG
ACAGCAATTGTAACTTACCCTTCTGCCTGGTCAGCAGAGATGGTATCCCTTCTTAAAAAGCTGC
TTGAACCTAATCCAGATCAACGCTTTTCTCACTTGACTGACATTCAGAATTTCCCTTATATGAG
TGACATGAACTGGGATGCAGTCCTGCAGAAGAGGCTCATTCCAGGCTTCGTTCCAACTAAAGGT
AGGCTTAATTGTGACCCTACTTTTGAACTGGAAGAAATGATTTTGGAGTCCAAACCTCTTCACA
AGAAAAAGAAGCGCCTGGCTAAAAAGGAGAAGGAAATGAAGAAATGTGACTCCCCTCAGATGTG
CCTTCTTCAAGAGCATCTTGACGCTGTTCAGAAGGAATTTATAATTTTCAACAGAGAAAAAGTA
AAAAGAGACTTTAATCAAAGACAAGCAAATATAGCCTTGGAGCAAACCAAAAACAACACAGAAG
AGGAGGATGGCCAGAATAACAACCTATAA

hide sequence

RefSeq Acc Id:

XM_039097002 ⟹ XP_038952930

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	18	35,258,865 - 35,374,985 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001178823	(Get FASTA)	NCBI Sequence Viewer
	XP_038952930	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL76496	(Get FASTA)	NCBI Sequence Viewer
	EDL76497	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

NP_001178823 ⟸ NM_001191894

- UniProtKB:

D3ZD18 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MGANTSSKAPVLDENEDVNFDHFEILRAIGKGSFGKVCIVQKNDTKKMYAMKYMNKQKCVERNE
VRNVFKELQIMQGLEHPFLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQNVHFQEDTVKLFIC
ELAMALDYLQSQRIIHRDMKPDNILLDEHGHVHITDFNIAAMLPKETRITTVAGTKPYMAPEMF
SSRKESGYSFAVDWWSLGVTAYELLRGRRPYHIRSSTSSKEIVNMFETAIVTYPSAWSAEMVSL
LKKLLEPNPDQRFSHLTDIQNFPYMSDMNWDAVLQKRLIPGFVPTKGRLNCDPTFELEEMILES
KPLHKKKKRLAKKEKEMKKCDSPQMCLLQEHLDAVQKEFIIFNREKVKRDFNQRQANIALEQTK
NNTEEEDGQNNNL

hide sequence

RefSeq Acc Id:

ENSRNOP00000036737 ⟸ ENSRNOT00000031370

RefSeq Acc Id:	XP_038952930 ⟸ XM_039097002
- Peptide Label:	isoform X1

RefSeq Acc Id:

ENSRNOP00000079735 ⟸ ENSRNOT00000115603

Protein Domains

Protein kinase

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D3ZD18-F1-model_v2	AlphaFold	D3ZD18	1-397	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1308338	AgrOrtholog
BioCyc Gene	G2FUF-7686	BioCyc
Ensembl Genes	ENSRNOG00000027066	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000036737	ENTREZGENE
	ENSRNOP00000036737.4	UniProtKB/TrEMBL
	ENSRNOP00000079735.1	UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000031370	ENTREZGENE
	ENSRNOT00000031370.7	UniProtKB/TrEMBL
	ENSRNOT00000115603.1	UniProtKB/TrEMBL
InterPro	Kinase-like_dom	UniProtKB/TrEMBL
	Prot_kinase_cat_dom	UniProtKB/TrEMBL
	Protein_kinase_ATP_BS	UniProtKB/TrEMBL
	Ser/Thr_prot_kinase_AS	UniProtKB/TrEMBL
KEGG Report	rno:364858	UniProtKB/TrEMBL
NCBI Gene	364858	ENTREZGENE
Pfam	Pkinase	UniProtKB/TrEMBL
PhenoGen	Stk32a	PhenoGen
PROSITE	PROTEIN_KINASE_ATP	UniProtKB/TrEMBL
	PROTEIN_KINASE_DOM	UniProtKB/TrEMBL
	PROTEIN_KINASE_ST	UniProtKB/TrEMBL
SMART	S_TKc	UniProtKB/TrEMBL
Superfamily-SCOP	Kinase_like	UniProtKB/TrEMBL
UniProt	A0A8I5ZNQ1_RAT	UniProtKB/TrEMBL
	D3ZD18	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-04-30	Stk32a	serine/threonine kinase 32A	Stk32a_predicted	serine/threonine kinase 32A (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-12	Stk32a_predicted	serine/threonine kinase 32A (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar