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Gene: Grpel2 (GrpE-like 2, mitochondrial) Rattus norvegicus
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Symbol: Grpel2
Name: GrpE-like 2, mitochondrial
Description: Predicted to have adenyl-nucleotide exchange factor activity and unfolded protein binding activity. Predicted to be involved in protein import into mitochondrial matrix. Predicted to localize to the PAM complex, Tim23 associated import motor. Orthologous to human GRPEL2 (GrpE like 2, mitochondrial); PARTICIPATES IN presequence pathway of mitochondrial protein import; INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; acrylamide; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: actin filament-associated protein 1-like 1; AFAP1-like protein 1; Afap1l1; grpE protein homolog 2, mitochondrial; LOC688777; similar to GrpE protein homolog 2, mitochondrial precursor (Mt-GrpE#2)
Orthologs:
Homo sapiens (human) : GRPEL2 (GrpE like 2, mitochondrial)  HGNC  Alliance
Mus musculus (house mouse) : Grpel2 (GrpE-like 2, mitochondrial)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Grpel2 (GrpE like 2, mitochondrial)
Pan paniscus (bonobo/pygmy chimpanzee) : GRPEL2 (GrpE like 2, mitochondrial)
Canis lupus familiaris (dog) : GRPEL2 (GrpE like 2, mitochondrial)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Grpel2 (GrpE like 2, mitochondrial)
Sus scrofa (pig) : GRPEL2 (GrpE like 2, mitochondrial)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01857,037,995 - 57,050,234 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01856,266,330 - 56,278,569 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41857,691,610 - 57,703,850 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1853,316,882 - 53,329,122 (-)NCBICelera
Cytogenetic Map18q12.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Grpel2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1585231
Created: 2006-11-19
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.