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Gene: Me2 (malic enzyme 2) Rattus norvegicus
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Symbol: Me2
Name: malic enzyme 2
RGD ID: 1310321
Description: Predicted to have malate dehydrogenase (decarboxylating) (NADP+) activity. Predicted to be involved in malate metabolic process; pyruvate metabolic process; and regulation of NADP metabolic process. Predicted to localize to mitochondrion. Orthologous to human ME2 (malic enzyme 2); PARTICIPATES IN Leigh disease pathway; primary hyperoxaluria type 2 pathway; pyruvate decarboxylase deficiency pathway; INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; 2-methoxyethanol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: LOC307270; malic enzyme 2, NAD(+)-dependent, mitochondrial; NAD-dependent malic enzyme, mitochondrial
Orthologs:
Homo sapiens (human) : ME2 (malic enzyme 2)  HGNC  Alliance
Mus musculus (house mouse) : Me2 (malic enzyme 2, NAD(+)-dependent, mitochondrial)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Me2 (malic enzyme 2)
Pan paniscus (bonobo/pygmy chimpanzee) : ME2 (malic enzyme 2)
Canis lupus familiaris (dog) : ME2 (malic enzyme 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Me2 (malic enzyme 2)
Sus scrofa (pig) : ME2 (malic enzyme 2)
Chlorocebus sabaeus (African green monkey) : ME2 (malic enzyme 2)
Heterocephalus glaber (naked mole-rat) : Me2 (malic enzyme 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01869,737,515 - 69,784,099 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1869,738,686 - 69,784,099 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01868,882,367 - 68,927,780 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41870,545,530 - 70,590,828 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11870,619,765 - 70,655,815 (-)NCBI
Celera1865,538,881 - 65,583,847 (-)NCBICelera
Cytogenetic Map18q12.2NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Me2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1310321
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.