piezo-type mechanosensitive ion channel component 2
RGD ID:
1582973
Description:
Predicted to enable mechanosensitive monoatomic cation channel activity. Predicted to be involved in cellular response to mechanical stimulus; detection of mechanical stimulus involved in sensory perception; and regulation of membrane potential. Predicted to act upstream of or within monoatomic cation transport. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in distal arthrogryposis type 3 and distal arthrogryposis type 5. Orthologous to human PIEZO2 (piezo type mechanosensitive ion channel component 2); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.
Fam38b; family with sequence similarity 38, member B; LOC307380; LOC688934; RGD1306866; similar to Hypothetical protein KIAA0233; similar to protein fam38b
[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of PIEZO2 mRNA
[bisphenol A co-treated with Fulvestrant] results in decreased methylation of PIEZO2 gene, [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of PIEZO2 mRNA
[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of PIEZO2 mRNA
[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of PIEZO2 mRNA
[Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased expression of PIEZO2 mRNA, [Air Pollutants results in increased abundance of Ozone] which results in decreased expression of PIEZO2 mRNA
[NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PIEZO2 mRNA
[perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of PIEZO2 mRNA, [perfluorooctane sulfonic acid co-treated with Pectins] results in decreased expression of PIEZO2 mRNA
[NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PIEZO2 mRNA
[NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PIEZO2 mRNA
