piezo-type mechanosensitive ion channel component 2
RGD ID:
1582973
Description:
Predicted to enable mechanosensitive monoatomic ion channel activity and monoatomic cation channel activity. Predicted to be involved in several processes, including cellular response to mechanical stimulus; detection of mechanical stimulus involved in sensory perception; and monoatomic cation transport. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in distal arthrogryposis type 3 and distal arthrogryposis type 5. Orthologous to human PIEZO2 (piezo type mechanosensitive ion channel component 2); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.
Fam38b; family with sequence similarity 38, member B; LOC307380; LOC688934; RGD1306866; similar to Hypothetical protein KIAA0233; similar to protein fam38b
[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of PIEZO2 mRNA
[bisphenol A co-treated with Fulvestrant] results in decreased methylation of PIEZO2 gene and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of PIEZO2 mRNA
[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of PIEZO2 mRNA
[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of PIEZO2 mRNA
[Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased expression of PIEZO2 mRNA and [Air Pollutants results in increased abundance of Ozone] which results in decreased expression of PIEZO2 mRNA
[NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PIEZO2 mRNA
[perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of PIEZO2 mRNA and [perfluorooctane sulfonic acid co-treated with Pectins] results in decreased expression of PIEZO2 mRNA
[NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PIEZO2 mRNA
[NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PIEZO2 mRNA
