Gene: Slc12a2 (solute carrier family 12 member 2) Rattus norvegicus
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Symbol: Slc12a2
Name: solute carrier family 12 member 2
Description: ENCODES a protein that exhibits sodium:potassium:chloride symporter activity; ammonium transmembrane transporter activity (ortholog); protein kinase binding (ortholog); INVOLVED IN aging; chloride transport; gamma-aminobutyric acid signaling pathway; ASSOCIATED WITH hypertension; middle cerebral artery infarction; sensorineural hearing loss; FOUND IN plasma membrane; apical plasma membrane (ortholog); basolateral plasma membrane (ortholog); INTERACTS WITH (+)-pilocarpine; (R)-lipoic acid; 17beta-estradiol
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Bsc2; Nkcc1; solute carrier family 12 (sodium/potassium/chloride transporter), member 2; solute carrier family 12 (sodium/potassium/chloride transporters), member 2; solute carrier family 12, member 2
Orthologs:
Homo sapiens (human) : SLC12A2 (solute carrier family 12 member 2)  HGNC  Alliance
Mus musculus (house mouse) : Slc12a2 (solute carrier family 12, member 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Slc12a2 (solute carrier family 12 member 2)
Pan paniscus (bonobo/pygmy chimpanzee) : SLC12A2 (solute carrier family 12 member 2)
Canis lupus familiaris (dog) : SLC12A2 (solute carrier family 12 member 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Slc12a2 (solute carrier family 12 member 2)
Sus scrofa (pig) : SLC12A2 (solute carrier family 12 member 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01852,917,124 - 52,985,281 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01852,104,434 - 52,172,638 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41853,673,215 - 53,741,352 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11853,735,140 - 53,805,295 (+)NCBI
Celera1849,478,614 - 49,546,320 (+)NCBICelera
Cytogenetic Map18q12.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Slc12a2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 620809
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-01-30
Status: ACTIVE