Mppe1 (metallophosphoesterase 1) - Rat Genome Database

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Gene: Mppe1 (metallophosphoesterase 1) Rattus norvegicus
Analyze
Symbol: Mppe1
Name: metallophosphoesterase 1
RGD ID: 1309184
Description: Predicted to enable GPI anchor binding activity; GPI-mannose ethanolamine phosphate phosphodiesterase activity; and manganese ion binding activity. Predicted to be involved in GPI anchor biosynthetic process and endoplasmic reticulum to Golgi vesicle-mediated transport. Predicted to be located in several cellular components, including cis-Golgi network; endoplasmic reticulum exit site; and endoplasmic reticulum-Golgi intermediate compartment. Orthologous to human MPPE1 (metallophosphoesterase 1); INTERACTS WITH 6-propyl-2-thiouracil; amitrole; amphetamine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC361344; post-GPI attachment to proteins factor 5
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81863,033,329 - 63,051,461 (-)NCBIGRCr8
mRatBN7.21860,763,418 - 60,781,553 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1860,763,419 - 60,781,553 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1862,836,092 - 62,854,510 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01863,534,833 - 63,553,257 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01861,384,005 - 61,402,164 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01862,946,952 - 62,966,174 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1862,946,953 - 62,965,538 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01862,133,742 - 62,151,775 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41863,738,125 - 63,756,486 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11863,811,325 - 63,824,805 (-)NCBI
Celera1858,871,180 - 58,889,224 (-)NCBICelera
Cytogenetic Map18q12.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:29374258  


Genomics

Comparative Map Data
Mppe1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81863,033,329 - 63,051,461 (-)NCBIGRCr8
mRatBN7.21860,763,418 - 60,781,553 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1860,763,419 - 60,781,553 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1862,836,092 - 62,854,510 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01863,534,833 - 63,553,257 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01861,384,005 - 61,402,164 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01862,946,952 - 62,966,174 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1862,946,953 - 62,965,538 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01862,133,742 - 62,151,775 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41863,738,125 - 63,756,486 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11863,811,325 - 63,824,805 (-)NCBI
Celera1858,871,180 - 58,889,224 (-)NCBICelera
Cytogenetic Map18q12.1NCBI
MPPE1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381811,882,622 - 11,908,317 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1811,882,622 - 11,908,366 (-)EnsemblGRCh38hg38GRCh38
GRCh371811,882,621 - 11,908,316 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361811,873,470 - 11,898,641 (-)NCBINCBI36Build 36hg18NCBI36
Celera1811,764,340 - 11,789,530 (-)NCBICelera
Cytogenetic Map18p11.21NCBI
HuRef1811,838,124 - 11,863,296 (-)NCBIHuRef
CHM1_11811,882,962 - 11,908,304 (-)NCBICHM1_1
T2T-CHM13v2.01812,045,331 - 12,071,022 (-)NCBIT2T-CHM13v2.0
Mppe1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391867,358,119 - 67,378,901 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1867,358,114 - 67,378,901 (-)EnsemblGRCm39 Ensembl
GRCm381867,225,043 - 67,245,830 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1867,225,043 - 67,245,830 (-)EnsemblGRCm38mm10GRCm38
MGSCv371867,385,184 - 67,405,484 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361867,350,899 - 67,371,199 (-)NCBIMGSCv36mm8
Celera1868,493,601 - 68,513,781 (-)NCBICelera
Cytogenetic Map18E1NCBI
cM Map1839.9NCBI
Mppe1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554021,172,704 - 1,181,908 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554021,167,711 - 1,182,410 (+)NCBIChiLan1.0ChiLan1.0
MPPE1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21726,115,631 - 26,141,007 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11811,808,230 - 11,832,880 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0182,397,423 - 2,423,209 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1184,662,348 - 4,686,832 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl184,662,348 - 4,686,262 (+)Ensemblpanpan1.1panPan2
MPPE1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1777,521,348 - 77,544,033 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl777,521,546 - 77,540,405 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha776,923,004 - 76,945,768 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0777,579,113 - 77,601,951 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl777,579,119 - 77,602,017 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1777,276,286 - 77,299,044 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0777,322,870 - 77,345,612 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0777,610,005 - 77,632,807 (-)NCBIUU_Cfam_GSD_1.0
Mppe1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049441,107,676 - 1,142,757 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936626361,270 - 373,629 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936626349,324 - 371,073 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MPPE1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl697,324,727 - 97,344,736 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1697,324,652 - 97,344,068 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2690,704,988 - 90,724,645 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MPPE1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11869,484,134 - 69,507,797 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1869,495,055 - 69,511,087 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605044,482,171 - 44,506,942 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mppe1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477019,505,326 - 19,526,750 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477019,504,774 - 19,526,710 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Mppe1
207 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:75
Count of miRNA genes:67
Interacting mature miRNAs:73
Transcripts:ENSRNOT00000025164
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2293708Bss46Bone structure and strength QTL 468.80.0001lumbar vertebra morphology trait (VT:0010494)lumbar vertebra cortical cross-sectional area (CMO:0001690)181179151863636873Rat
1578661Bss20Bone structure and strength QTL 203.7femur morphology trait (VT:0000559)femoral neck cross-sectional area (CMO:0001697)181179151883218561Rat
1578667Bss21Bone structure and strength QTL 213.5femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)181179151883218561Rat
1358193Emca2Estrogen-induced mammary cancer QTL 21.6mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)181800759963571040Rat
1600373Mamtr6Mammary tumor resistance QTL 6mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)181927890183218561Rat
1331741Bp232Blood pressure QTL 2323.59112arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)182137289383213037Rat
1331733Bp233Blood pressure QTL 2333.97196arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)182479697779788953Rat
2325839Bp348Blood pressure QTL 3480.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)182557098570570985Rat
2293704Bss35Bone structure and strength QTL 354.590.0002femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)182896485373964853Rat
2300157Bmd66Bone mineral density QTL 6613.10.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)182896485373964853Rat
2300177Bmd65Bone mineral density QTL 6519.70.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)182896485373964853Rat
9589816Gluco68Glucose level QTL 687.250.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)182979296574792965Rat
8694378Bw157Body weight QTL 1573.590.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)182979296574792965Rat
9590318Scort22Serum corticosterone level QTL 227.640.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)182979296574792965Rat
1331754Bp230Blood pressure QTL 2304.61609arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)182979296574792965Rat
738005Anxrr11Anxiety related response QTL 113.4exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)183003981375039813Rat
1331727Bp237Blood pressure QTL 2373.053arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183135940861698465Rat
61429Cia17Collagen induced arthritis QTL 174.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)183135940870263868Rat
2303120Mamtr8Mammary tumor resistance QTL 80.001mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)183135940883218561Rat
631274Sprol1Serum protein level QTL 15.3blood total protein amount (VT:0005567)serum total protein level (CMO:0000661)183139332077209694Rat
631518Bw11Body weight QTL 112.8body mass (VT:0001259)body weight (CMO:0000012)183587072380870723Rat
61367Iddm4Insulin dependent diabetes mellitus QTL 42.330.0074blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)183819245583192455Rat
1598826Anxrr20Anxiety related response QTL 203.04body movement coordination trait (VT:0005424)number of rearing movements in an experimental apparatus (CMO:0001752)184143297183828827Rat
6893683Bw110Body weight QTL 1102.70.002body mass (VT:0001259)body weight (CMO:0000012)184334502283828827Rat
8694366Abfw8Abdominal fat weight QTL 86.380.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)184664067583828827Rat
8694432Bw165Body weight QTL 1653.810.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)184664067583828827Rat
9589041Epfw12Epididymal fat weight QTL 1217.080.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)184664067583828827Rat
2303571Bw92Body weight QTL 923body mass (VT:0001259)body weight (CMO:0000012)184852004483828827Rat
2303584Gluco55Glucose level QTL 552blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)184852004483828827Rat
7411719Strs5Sensitivity to stroke QTL 59.4cerebrum integrity trait (VT:0010549)percentage of study population developing cerebrovascular lesions during a period of time (CMO:0000932)184999995865845095Rat
2293658Bmd23Bone mineral density QTL 237.30.0001femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)185146473363636873Rat
738008Hcar14Hepatocarcinoma resistance QTL 144.3liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion number (CMO:0001462)185146473383218561Rat
1331752Bw27Body weight QTL 272.963body mass (VT:0001259)body weight (CMO:0000012)185229287565845095Rat
1359020Ppulsi2Prepulse inhibition QTL 22.71prepulse inhibition trait (VT:0003088)acoustic startle response measurement (CMO:0001519)185229287573997283Rat
1600375Mcs22Mammary carcinoma susceptibility QTL 223.3mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)185253976363933058Rat
631509Sald2Serum aldosterone level QTL 22.9blood aldosterone amount (VT:0005346)serum aldosterone level (CMO:0000487)185253976369140759Rat
12880368Bw187Body weight QTL 1870.045body mass (VT:0001259)body weight (CMO:0000012)185253976376104388Rat
12904067Cm122Cardiac mass QTL 1220.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)185253976376104388Rat
12904069Cm123Cardiac mass QTL 1230.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)185253976376104388Rat
12904070Cm124Cardiac mass QTL 1240.01heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)185253976376104388Rat
12904071Am18Aortic mass QTL 180.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)185253976376104388Rat
12904073Kidm71Kidney mass QTL 710.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)185253976376104388Rat
2301417Bp319Blood pressure QTL 3190.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)185253976376104388Rat
1300125Rf26Renal function QTL 263.2urine potassium amount (VT:0010539)urine potassium excretion rate (CMO:0000761)185253986365844950Rat
1298072Cia26Collagen induced arthritis QTL 263.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)185470976983828827Rat
631834Sach3Saccharin preference QTL 33.90.01consumption behavior trait (VT:0002069)calculated saccharin drink intake volume (CMO:0001600)185880568763636873Rat
724542Kidm2Kidney mass QTL 22.6kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)185917211583828827Rat
2312600Bp341Blood pressure QTL 3410.05arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)185933040970263868Rat
2301969Bp324Blood pressure QTL 3244.05arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)185971241776477814Rat
70185BpQTLcluster15Blood pressure QTL cluster 154.61arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)185971241776477814Rat
70185BpQTLcluster15Blood pressure QTL cluster 154.61arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)185971241776477814Rat
70185BpQTLcluster15Blood pressure QTL cluster 154.61arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)185971241776477814Rat
70185BpQTLcluster15Blood pressure QTL cluster 154.61arterial blood pressure trait (VT:2000000)absolute change in systolic blood pressure (CMO:0000607)185971241776477814Rat
1331770Bp234Blood pressure QTL 2343.807arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)185979647871893566Rat
6903353Bp353Blood pressure QTL 3532.8arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)185979647883828827Rat
6903356Bp354Blood pressure QTL 3544.6arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)185979647883828827Rat
61384Bp48Blood pressure QTL 4819.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)186062231177209844Rat
631675Iddm15Insulin dependent diabetes mellitus QTL 15urine glucose amount (VT:0001758)percentage of study population developing diabetes mellitus during a period of time (CMO:0001114)186062231177209844Rat

Markers in Region
D18Wox11  
Rat AssemblyChrPosition (strand)SourceJBrowse
RGSC_v3.41863,737,840 - 63,737,956UniSTSRGSC3.4
RGSC_v3.41863,737,839 - 63,737,956RGDRGSC3.4
RGSC_v3.11863,811,040 - 63,811,157RGD
Celera1858,870,895 - 58,871,011UniSTS
RH 3.4 Map18616.3RGD
RH 2.0 Map18298.8RGD
D18Mit17  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21860,763,132 - 60,763,249 (+)MAPPERmRatBN7.2
Rnor_6.01862,946,667 - 62,946,783NCBIRnor6.0
Rnor_5.01862,133,457 - 62,133,573UniSTSRnor5.0
RGSC_v3.41832,458,754 - 32,458,974RGDRGSC3.4
RGSC_v3.41863,737,840 - 63,737,956UniSTSRGSC3.4
RGSC_v3.11863,811,040 - 63,811,157RGD
Celera1858,870,895 - 58,871,011UniSTS
RH 3.4 Map18616.3UniSTS
Cytogenetic Map18q12.1UniSTS
Cytogenetic Map18q12.1-q12.2UniSTS
D18Arb5  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21860,763,053 - 60,763,320 (+)MAPPERmRatBN7.2
Rnor_6.01862,946,588 - 62,946,854NCBIRnor6.0
Rnor_5.01862,133,378 - 62,133,644UniSTSRnor5.0
RGSC_v3.41863,737,760 - 63,738,027RGDRGSC3.4
RGSC_v3.41863,737,761 - 63,738,027UniSTSRGSC3.4
RGSC_v3.11863,810,961 - 63,811,228RGD
Celera1858,870,816 - 58,871,082UniSTS
FHH x ACI Map1841.94RGD
FHH x ACI Map1841.94UniSTS
Cytogenetic Map18q12.1UniSTS
Cytogenetic Map18q12.1-q12.2UniSTS
BF394247  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21860,769,251 - 60,769,413 (+)MAPPERmRatBN7.2
Rnor_6.01862,952,786 - 62,952,947NCBIRnor6.0
Rnor_5.01862,139,576 - 62,139,737UniSTSRnor5.0
RGSC_v3.41863,743,959 - 63,744,120UniSTSRGSC3.4
Celera1858,877,014 - 58,877,175UniSTS
RH 3.4 Map18617.6UniSTS
Cytogenetic Map18q12.1UniSTS
RH141722  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21860,763,602 - 60,763,795 (+)MAPPERmRatBN7.2
Rnor_6.01862,947,137 - 62,947,329NCBIRnor6.0
Rnor_5.01862,133,927 - 62,134,119UniSTSRnor5.0
RGSC_v3.41863,738,310 - 63,738,502UniSTSRGSC3.4
Celera1858,871,365 - 58,871,557UniSTS
RH 3.4 Map18616.3UniSTS
Cytogenetic Map18q12.1UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 30 28 14 18 14 1 1 31 34 28 11 1
Low 13 29 27 1 27 7 10 43 1 13 7
Below cutoff

Sequence


RefSeq Acc Id: ENSRNOT00000025164   ⟹   ENSRNOP00000025164
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1860,763,419 - 60,781,553 (-)Ensembl
Rnor_6.0 Ensembl1862,946,953 - 62,965,538 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000112222   ⟹   ENSRNOP00000076576
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1860,763,419 - 60,781,553 (-)Ensembl
RefSeq Acc Id: NM_001108435   ⟹   NP_001101905
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81863,033,329 - 63,051,461 (-)NCBI
mRatBN7.21860,763,418 - 60,781,553 (-)NCBI
Rnor_6.01862,946,952 - 62,965,538 (-)NCBI
Rnor_5.01862,133,742 - 62,151,775 (-)NCBI
RGSC_v3.41863,738,125 - 63,756,486 (-)RGD
Celera1858,871,180 - 58,889,224 (-)RGD
Sequence:
RefSeq Acc Id: XM_006254879   ⟹   XP_006254941
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81863,033,329 - 63,051,059 (-)NCBI
mRatBN7.21860,763,418 - 60,781,158 (-)NCBI
Rnor_6.01862,947,031 - 62,965,257 (-)NCBI
Rnor_5.01862,133,742 - 62,151,775 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006254881   ⟹   XP_006254943
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81863,033,329 - 63,051,341 (-)NCBI
mRatBN7.21860,763,418 - 60,781,435 (-)NCBI
Rnor_6.01862,947,031 - 62,966,173 (-)NCBI
Rnor_5.01862,133,742 - 62,151,775 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017600999   ⟹   XP_017456488
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81863,033,329 - 63,051,341 (-)NCBI
mRatBN7.21860,764,123 - 60,781,435 (-)NCBI
Rnor_6.01862,947,710 - 62,966,174 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039096981   ⟹   XP_038952909
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81863,033,329 - 63,051,341 (-)NCBI
mRatBN7.21860,763,418 - 60,781,435 (-)NCBI
RefSeq Acc Id: XM_039096982   ⟹   XP_038952910
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81863,033,329 - 63,051,341 (-)NCBI
mRatBN7.21860,763,418 - 60,781,435 (-)NCBI
RefSeq Acc Id: XM_039096983   ⟹   XP_038952911
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81863,035,782 - 63,051,341 (-)NCBI
mRatBN7.21860,765,871 - 60,781,435 (-)NCBI
RefSeq Acc Id: XM_063277483   ⟹   XP_063133553
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81863,033,329 - 63,051,059 (-)NCBI
RefSeq Acc Id: NP_001101905   ⟸   NM_001108435
- UniProtKB: B1WC86 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006254943   ⟸   XM_006254881
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_006254941   ⟸   XM_006254879
- Peptide Label: isoform X1
- UniProtKB: B1WC86 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_017456488   ⟸   XM_017600999
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: ENSRNOP00000025164   ⟸   ENSRNOT00000025164
RefSeq Acc Id: XP_038952910   ⟸   XM_039096982
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038952909   ⟸   XM_039096981
- Peptide Label: isoform X3
- UniProtKB: A0A8I5Y647 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038952911   ⟸   XM_039096983
- Peptide Label: isoform X6
RefSeq Acc Id: ENSRNOP00000076576   ⟸   ENSRNOT00000112222
RefSeq Acc Id: XP_063133553   ⟸   XM_063277483
- Peptide Label: isoform X2
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-B1WC86-F1-model_v2 AlphaFold B1WC86 1-394 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13700840
Promoter ID:EPDNEW_R11364
Type:single initiation site
Name:Mppe1_1
Description:metallophosphoesterase 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01862,965,518 - 62,965,578EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309184 AgrOrtholog
BioCyc Gene G2FUF-7150 BioCyc
Ensembl Genes ENSRNOG00000018648 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSRNOG00055010113 UniProtKB/Swiss-Prot
  ENSRNOG00060010576 UniProtKB/Swiss-Prot
  ENSRNOG00065020120 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000025164 ENTREZGENE
  ENSRNOT00000025164.5 UniProtKB/Swiss-Prot
  ENSRNOT00000112222.1 UniProtKB/TrEMBL
  ENSRNOT00055017053 UniProtKB/Swiss-Prot
  ENSRNOT00060017874 UniProtKB/Swiss-Prot
  ENSRNOT00065033933 UniProtKB/Swiss-Prot
Gene3D-CATH 3.60.21.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7105580 IMAGE-MGC_LOAD
InterPro Calcineurin-like_PHP_ApaH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Metallo-depent_PP-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MPP_MPPE1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PGAP5/Cdc1/Ted1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:361344 UniProtKB/Swiss-Prot
MGC_CLONE MGC:187998 IMAGE-MGC_LOAD
NCBI Gene 361344 ENTREZGENE
PANTHER METALLOPHOSPHOESTERASE 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR13315 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Metallophos UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Mppe1 PhenoGen
RatGTEx ENSRNOG00000018648 RatGTEx
  ENSRNOG00055010113 RatGTEx
  ENSRNOG00060010576 RatGTEx
  ENSRNOG00065020120 RatGTEx
Superfamily-SCOP SSF56300 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I5Y647 ENTREZGENE, UniProtKB/TrEMBL
  B1WC86 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Mppe1  metallophosphoesterase 1   Mppe1_predicted  metallophosphoesterase 1 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Mppe1_predicted  metallophosphoesterase 1 (predicted)      Symbol and Name status set to approved 70820 APPROVED