Katnal2 (katanin catalytic subunit A1 like 2) - Rat Genome Database

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Gene: Katnal2 (katanin catalytic subunit A1 like 2) Rattus norvegicus
Analyze
Symbol: Katnal2
Name: katanin catalytic subunit A1 like 2
RGD ID: 1564708
Description: Predicted to enable several functions, including ATP binding activity; ATP hydrolysis activity; and microtubule severing ATPase activity. Predicted to be involved in microtubule severing. Predicted to be located in cytoplasm; microtubule; and spindle pole. Orthologous to human KATNAL2 (katanin catalytic subunit A1 like 2); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; bisphenol A.
Type: protein-coding
RefSeq Status: MODEL
Previously known as: katanin p60 ATPase-containing subunit A-like 2; katanin p60 subunit A-like 2; LOC307253; RGD1564708; similar to RIKEN cDNA 3110023G01
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21870,531,759 - 70,607,886 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1870,531,754 - 70,608,082 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.01873,283,756 - 73,360,367 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1873,283,748 - 73,360,373 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01872,961,624 - 73,036,691 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41873,955,032 - 73,998,321 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1869,056,377 - 69,130,209 (-)NCBICelera
Cytogenetic Map18q12.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (ISO)
microtubule  (ISO)
spindle  (ISO)
spindle pole  (ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:26929214  


Genomics

Comparative Map Data
Katnal2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21870,531,759 - 70,607,886 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1870,531,754 - 70,608,082 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.01873,283,756 - 73,360,367 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1873,283,748 - 73,360,373 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01872,961,624 - 73,036,691 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41873,955,032 - 73,998,321 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1869,056,377 - 69,130,209 (-)NCBICelera
Cytogenetic Map18q12.3NCBI
KATNAL2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381846,917,594 - 47,102,243 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1846,917,492 - 47,103,478 (+)EnsemblGRCh38hg38GRCh38
GRCh371844,497,557 - 44,628,614 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361842,780,785 - 42,881,661 (+)NCBINCBI36Build 36hg18NCBI36
Build 341842,780,784 - 42,881,659NCBI
Celera1841,429,772 - 41,479,137 (+)NCBICelera
Cytogenetic Map18q21.1NCBI
HuRef1841,427,284 - 41,476,671 (+)NCBIHuRef
CHM1_11844,453,895 - 44,623,785 (+)NCBICHM1_1
T2T-CHM13v2.01847,108,258 - 47,292,540 (+)NCBIT2T-CHM13v2.0
Katnal2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391877,063,725 - 77,135,007 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1877,064,844 - 77,135,004 (-)EnsemblGRCm39 Ensembl
GRCm381876,976,029 - 77,047,311 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1876,977,148 - 77,047,308 (-)EnsemblGRCm38mm10GRCm38
MGSCv371877,231,939 - 77,286,035 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361877,197,650 - 77,251,746 (-)NCBIMGSCv36mm8
Celera1878,176,788 - 78,230,801 (-)NCBICelera
Cytogenetic Map18E3NCBI
Katnal2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540232,407,745 - 32,490,009 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540232,407,994 - 32,490,009 (+)NCBIChiLan1.0ChiLan1.0
KATNAL2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11843,729,436 - 43,850,517 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1843,758,249 - 43,850,517 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01840,196,170 - 40,492,175 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
KATNAL2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1744,359,777 - 44,454,340 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl744,366,182 - 44,437,346 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha743,846,924 - 43,938,162 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0744,316,039 - 44,407,835 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl744,323,759 - 44,390,306 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1744,016,052 - 44,107,814 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0744,070,112 - 44,161,863 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0744,353,890 - 44,445,628 (-)NCBIUU_Cfam_GSD_1.0
Katnal2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494440,598,419 - 40,664,390 (-)NCBIHiC_Itri_2
SpeTri2.0NW_00493698337,876 - 75,556 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KATNAL2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl196,566,848 - 96,676,519 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1196,566,852 - 96,676,184 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
KATNAL2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11833,848,471 - 33,967,832 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1833,848,748 - 33,907,092 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660508,152,696 - 8,306,844 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Katnal2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477810,561,459 - 10,663,686 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477810,599,429 - 10,664,022 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1578661Bss20Bone structure and strength QTL 203.7femur morphology trait (VT:0000559)femoral neck cross-sectional area (CMO:0001697)181179151883218561Rat
1578667Bss21Bone structure and strength QTL 213.5femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)181179151883218561Rat
1600373Mamtr6Mammary tumor resistance QTL 6mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)181927890183218561Rat
1331741Bp232Blood pressure QTL 2323.59112arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)182137289383213037Rat
1331733Bp233Blood pressure QTL 2333.97196arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)182479697779788953Rat
2325839Bp348Blood pressure QTL 3480.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)182557098570570985Rat
2293704Bss35Bone structure and strength QTL 354.590.0002femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)182896485373964853Rat
2300157Bmd66Bone mineral density QTL 6613.10.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)182896485373964853Rat
2300177Bmd65Bone mineral density QTL 6519.70.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)182896485373964853Rat
9589816Gluco68Glucose level QTL 687.250.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)182979296574792965Rat
8694378Bw157Body weight QTL 1573.590.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)182979296574792965Rat
9590318Scort22Serum corticosterone level QTL 227.640.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)182979296574792965Rat
1331754Bp230Blood pressure QTL 2304.61609arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)182979296574792965Rat
738005Anxrr11Anxiety related response QTL 113.4exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)183003981375039813Rat
2303120Mamtr8Mammary tumor resistance QTL 80.001mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)183135940883218561Rat
631274Sprol1Serum protein level QTL 15.3blood total protein amount (VT:0005567)serum total protein level (CMO:0000661)183139332077209694Rat
631518Bw11Body weight QTL 112.8body mass (VT:0001259)body weight (CMO:0000012)183587072380870723Rat
61367Iddm4Insulin dependent diabetes mellitus QTL 42.330.0074blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)183819245583192455Rat
1598826Anxrr20Anxiety related response QTL 203.04body movement coordination trait (VT:0005424)number of rearing movements in an experimental apparatus (CMO:0001752)184143297183828827Rat
6893683Bw110Body weight QTL 1102.70.002body mass (VT:0001259)body weight (CMO:0000012)184334502283828827Rat
8694366Abfw8Abdominal fat weight QTL 86.380.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)184664067583828827Rat
8694432Bw165Body weight QTL 1653.810.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)184664067583828827Rat
9589041Epfw12Epididymal fat weight QTL 1217.080.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)184664067583828827Rat
2303571Bw92Body weight QTL 923body mass (VT:0001259)body weight (CMO:0000012)184852004483828827Rat
2303584Gluco55Glucose level QTL 552blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)184852004483828827Rat
738008Hcar14Hepatocarcinoma resistance QTL 144.3liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion number (CMO:0001462)185146473383218561Rat
1359020Ppulsi2Prepulse inhibition QTL 22.71prepulse inhibition trait (VT:0003088)acoustic startle response measurement (CMO:0001519)185229287573997283Rat
12880368Bw187Body weight QTL 1870.045body mass (VT:0001259)body weight (CMO:0000012)185253976376104388Rat
12904067Cm122Cardiac mass QTL 1220.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)185253976376104388Rat
12904069Cm123Cardiac mass QTL 1230.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)185253976376104388Rat
12904070Cm124Cardiac mass QTL 1240.01heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)185253976376104388Rat
12904071Am18Aortic mass QTL 180.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)185253976376104388Rat
12904073Kidm71Kidney mass QTL 710.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)185253976376104388Rat
2301417Bp319Blood pressure QTL 3190.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)185253976376104388Rat
1298072Cia26Collagen induced arthritis QTL 263.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)185470976983828827Rat
724542Kidm2Kidney mass QTL 22.6kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)185917211583828827Rat
2301969Bp324Blood pressure QTL 3244.05arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)185971241776477814Rat
70185BpQTLcluster15Blood pressure QTL cluster 154.61arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)185971241776477814Rat
70185BpQTLcluster15Blood pressure QTL cluster 154.61arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)185971241776477814Rat
70185BpQTLcluster15Blood pressure QTL cluster 154.61arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)185971241776477814Rat
70185BpQTLcluster15Blood pressure QTL cluster 154.61arterial blood pressure trait (VT:2000000)absolute change in systolic blood pressure (CMO:0000607)185971241776477814Rat
1331770Bp234Blood pressure QTL 2343.807arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)185979647871893566Rat
6903353Bp353Blood pressure QTL 3532.8arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)185979647883828827Rat
6903356Bp354Blood pressure QTL 3544.6arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)185979647883828827Rat
61384Bp48Blood pressure QTL 4819.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)186062231177209844Rat
631675Iddm15Insulin dependent diabetes mellitus QTL 15urine glucose amount (VT:0001758)percentage of study population developing diabetes mellitus during a period of time (CMO:0001114)186062231177209844Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:94
Count of miRNA genes:82
Interacting mature miRNAs:84
Transcripts:ENSRNOT00000023967, ENSRNOT00000048702
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 7
Low 2 10 9 2 9 69 23 31 11
Below cutoff 2 16 29 14 15 14 2 3 5 12 3 2

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_006222634 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006222635 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006254971 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006254972 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008772209 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008772210 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008774152 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017587896 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017587897 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017601136 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017601137 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039097298 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039097299 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039097300 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001834522 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001834523 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide CH474069 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000301 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000048702   ⟹   ENSRNOP00000042060
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1870,531,754 - 70,608,082 (-)Ensembl
Rnor_6.0 Ensembl1873,283,748 - 73,360,373 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000098783   ⟹   ENSRNOP00000090814
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1870,531,754 - 70,563,292 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000117058   ⟹   ENSRNOP00000078692
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1870,548,070 - 70,608,082 (-)Ensembl
RefSeq Acc Id: XM_006254971   ⟹   XP_006255033
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21870,531,759 - 70,607,886 (-)NCBI
Rnor_6.01873,283,756 - 73,360,367 (-)NCBI
Rnor_5.01872,961,624 - 73,036,691 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006254972   ⟹   XP_006255034
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21870,531,759 - 70,607,886 (-)NCBI
Rnor_6.01873,283,756 - 73,360,367 (-)NCBI
Rnor_5.01872,961,624 - 73,036,691 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008772209   ⟹   XP_008770431
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21870,531,759 - 70,607,886 (-)NCBI
Rnor_6.01873,283,756 - 73,360,367 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039097298   ⟹   XP_038953226
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21870,531,759 - 70,607,860 (-)NCBI
RefSeq Acc Id: XM_039097299   ⟹   XP_038953227
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21870,531,759 - 70,568,173 (-)NCBI
RefSeq Acc Id: XM_039097300   ⟹   XP_038953228
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21870,531,759 - 70,568,173 (-)NCBI
Reference Sequences
RefSeq Acc Id: XP_006255034   ⟸   XM_006254972
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_006255033   ⟸   XM_006254971
- Peptide Label: isoform X1
- UniProtKB: F1M5A4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008770431   ⟸   XM_008772209
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: ENSRNOP00000042060   ⟸   ENSRNOT00000048702
RefSeq Acc Id: XP_038953226   ⟸   XM_039097298
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038953228   ⟸   XM_039097300
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038953227   ⟸   XM_039097299
- Peptide Label: isoform X5
RefSeq Acc Id: ENSRNOP00000078692   ⟸   ENSRNOT00000117058
RefSeq Acc Id: ENSRNOP00000090814   ⟸   ENSRNOT00000098783
Protein Domains
AAA   LisH

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F1M5A4-F1-model_v2 AlphaFold F1M5A4 1-537 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13700878
Promoter ID:EPDNEW_R11401
Type:multiple initiation site
Name:Katnal2_1
Description:katanin catalytic subunit A1 like 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01873,360,347 - 73,360,407EPDNEW

Strain Variation

Strain Sequence Variants (mRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
Damaging Variants


Assembly: Rnor_5.0

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
18 72987517 72987518 C A snv F344/NSlc (KyushuU)
18 72987522 72987523 T G snv LE/Stm (KyushuU), F344/NSlc (KyushuU)


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1564708 AgrOrtholog
BioCyc Gene G2FUF-6947 BioCyc
Ensembl Genes ENSRNOG00000017788 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000042060 ENTREZGENE
  ENSRNOP00000042060.6 UniProtKB/TrEMBL
  ENSRNOP00000078692.1 UniProtKB/TrEMBL
  ENSRNOP00000090814.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000048702 ENTREZGENE
  ENSRNOT00000048702.7 UniProtKB/TrEMBL
  ENSRNOT00000098783.1 UniProtKB/TrEMBL
  ENSRNOT00000117058.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/TrEMBL
InterPro AAA_lid_3 UniProtKB/TrEMBL
  ATPase_AAA+_core UniProtKB/TrEMBL
  ATPase_AAA_core UniProtKB/TrEMBL
  Katanin_p60_AL2 UniProtKB/TrEMBL
  LisH_dimerisation UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
KEGG Report rno:307253 UniProtKB/TrEMBL
NCBI Gene 307253 ENTREZGENE
Pfam AAA UniProtKB/TrEMBL
  AAA_lid_3 UniProtKB/TrEMBL
  LisH UniProtKB/TrEMBL
PhenoGen Katnal2 PhenoGen
PROSITE LISH UniProtKB/TrEMBL
SMART AAA UniProtKB/TrEMBL
  LisH UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A0A8I5ZLG7_RAT UniProtKB/TrEMBL
  A0A8I6GJ64_RAT UniProtKB/TrEMBL
  F1M5A4 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-03-29 Katnal2  katanin catalytic subunit A1 like 2  Katnal2  katanin p60 subunit A-like 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-07 Katnal2  katanin p60 subunit A-like 2  RGD1564708_predicted  similar to RIKEN cDNA 3110023G01 (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-07 RGD1564708_predicted  similar to RIKEN cDNA 3110023G01 (predicted)  LOC307253  similar to RIKEN cDNA 3110023G01  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC307253  similar to RIKEN cDNA 3110023G01      Symbol and Name status set to provisional 70820 PROVISIONAL