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Gene: Apcdd1 (APC down-regulated 1) Rattus norvegicus
Symbol: Apcdd1
Name: APC down-regulated 1
RGD ID: 1589962
Description: Predicted to have Wnt-protein binding activity and identical protein binding activity. Predicted to be involved in several processes, including astrocyte cell migration; hair follicle development; and regulation of odontogenesis of dentin-containing tooth. Predicted to localize to integral component of plasma membrane. Human ortholog(s) of this gene implicated in hypotrichosis 1. Orthologous to human APCDD1 (APC down-regulated 1); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.
Type: protein-coding
RefSeq Status: MODEL
Also known as: adenomatosis polyposis coli down-regulated 1; LOC689616; similar to adenomatosis polyposis coli down-regulated 1
Homo sapiens (human) : APCDD1 (APC down-regulated 1)  HGNC  Alliance
Mus musculus (house mouse) : Apcdd1 (adenomatosis polyposis coli down-regulated 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Apcdd1 (APC down-regulated 1)
Pan paniscus (bonobo/pygmy chimpanzee) : APCDD1 (APC down-regulated 1)
Canis lupus familiaris (dog) : APCDD1 (APC down-regulated 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Apcdd1 (APC down-regulated 1)
Sus scrofa (pig) : APCDD1 (APC down-regulated 1)
Chlorocebus sabaeus (African green monkey) : APCDD1 (APC down-regulated 1)
Heterocephalus glaber (naked mole-rat) : Apcdd1 (APC down-regulated 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01858,270,398 - 58,300,982 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1858,270,410 - 58,301,002 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01857,494,395 - 57,523,899 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41859,088,709 - 59,091,205 (+)NCBIRGSC3.4rn4RGSC3.4
Celera1854,532,957 - 54,563,430 (+)NCBICelera
Cytogenetic Map18q12.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Apcdd1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1589962
Created: 2006-11-20
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.