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Gene: Mapk4 (mitogen-activated protein kinase 4) Rattus norvegicus
Symbol: Mapk4
Name: mitogen-activated protein kinase 4
Description: Predicted to have MAP kinase activity; protein dimerization activity; and protein kinase binding activity. Predicted to be involved in cellular response to organic substance; intracellular signal transduction; and regulation of gene expression. Predicted to localize to the cytoplasm and nucleus. Orthologous to human MAPK4 (mitogen-activated protein kinase 4); INTERACTS WITH 1-naphthyl isothiocyanate; 3-chloropropane-1,2-diol; ammonium chloride.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: ERK-4; extracellular signal-regulated kinase 4; MAP kinase 4; MAP kinase isoform p63; MAPK 4; mitogen activated protein kinase 4; MNK2; p63-MAPK
Homo sapiens (human) : MAPK4 (mitogen-activated protein kinase 4)  HGNC  Alliance
Mus musculus (house mouse) : Mapk4 (mitogen-activated protein kinase 4)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mapk4 (mitogen-activated protein kinase 4)
Pan paniscus (bonobo/pygmy chimpanzee) : MAPK4 (mitogen-activated protein kinase 4)
Canis lupus familiaris (dog) : MAPK4 (mitogen-activated protein kinase 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mapk4 (mitogen-activated protein kinase 4)
Sus scrofa (pig) : MAPK4 (mitogen-activated protein kinase 4)
Chlorocebus sabaeus (green monkey) : MAPK4 (mitogen-activated protein kinase 4)
Heterocephalus glaber (naked mole-rat) : Mapk4 (mitogen-activated protein kinase 4)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01869,894,692 - 70,043,634 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1869,894,684 - 69,944,632 (-)Ensembl
Rnor_5.01869,038,436 - 69,087,394 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41870,707,645 - 70,755,517 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11870,784,791 - 70,828,233 (-)NCBI
Celera1865,696,152 - 65,744,928 (-)NCBICelera
Cytogenetic Map18q12.2NCBI
JBrowse: View Region in Genome Browser (JBrowse)

References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Mapk4
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3047
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.