Gramd2b (GRAM domain containing 2B) - Rat Genome Database

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Gene: Gramd2b (GRAM domain containing 2B) Rattus norvegicus
Analyze
Symbol: Gramd2b
Name: GRAM domain containing 2B
RGD ID: 1311016
Description: Predicted to enable identical protein binding activity. Predicted to be located in membrane. Predicted to be active in cytoplasmic microtubule. Orthologous to human GRAMD2B (GRAM domain containing 2B); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 2,2',4,4'-Tetrabromodiphenyl ether.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: GRAM domain containing 3; GRAM domain-containing protein 2B; GRAM domain-containing protein 3; Gramd3; LOC307288; MGC109479; RGD1311016; similar to RIKEN cDNA 9130427A09
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81852,082,128 - 52,180,056 (+)NCBIGRCr8
mRatBN7.21849,884,014 - 49,981,955 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1849,884,014 - 49,981,953 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1851,922,261 - 52,020,135 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01852,629,934 - 52,728,049 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01850,428,129 - 50,526,003 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01851,492,196 - 51,591,028 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1851,492,196 - 51,591,026 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01850,688,264 - 50,786,066 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41852,171,662 - 52,271,700 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11852,217,156 - 52,317,193 (+)NCBI
Celera1848,029,393 - 48,127,288 (+)NCBICelera
Cytogenetic Map18q11-q12.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
(1->4)-beta-D-glucan  (ISO)
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (ISO)
1,2-dimethylhydrazine  (ISO)
1-naphthyl isothiocyanate  (EXP)
17beta-estradiol  (EXP,ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,3',4,4',5-Pentachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2,6-dinitrotoluene  (EXP)
2-bromohexadecanoic acid  (ISO)
2-palmitoylglycerol  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
acrolein  (ISO)
actinomycin D  (ISO)
aflatoxin B1  (ISO)
alpha-pinene  (ISO)
amphetamine  (EXP)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
Benzo[k]fluoranthene  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
camptothecin  (ISO)
chlorpyrifos  (ISO)
chromium(6+)  (ISO)
ciglitazone  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
cyclosporin A  (ISO)
DDE  (ISO)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (EXP)
disodium selenite  (ISO)
disulfiram  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
entinostat  (ISO)
ethanol  (ISO)
finasteride  (EXP)
fluoxetine  (EXP)
flutamide  (EXP)
folic acid  (ISO)
formaldehyde  (ISO)
glyphosate  (EXP)
indometacin  (ISO)
lithium chloride  (ISO)
N,N-diethyl-m-toluamide  (EXP)
nefazodone  (EXP)
Nutlin-3  (ISO)
oxaliplatin  (EXP)
ozone  (ISO)
paracetamol  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
permethrin  (EXP)
phenylmercury acetate  (ISO)
phorone  (EXP)
pirinixic acid  (ISO)
potassium chromate  (ISO)
propanal  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sulforaphane  (ISO)
sunitinib  (ISO)
temozolomide  (ISO)
tetrachloroethene  (ISO)
titanium dioxide  (ISO)
topotecan  (EXP)
trichostatin A  (ISO)
triphenyl phosphate  (EXP,ISO)
urethane  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
vincristine  (ISO)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasmic microtubule  (IBA,ISO,ISS)
membrane  (IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:15489334   PMID:23264731   PMID:25416956  


Genomics

Comparative Map Data
Gramd2b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81852,082,128 - 52,180,056 (+)NCBIGRCr8
mRatBN7.21849,884,014 - 49,981,955 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1849,884,014 - 49,981,953 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1851,922,261 - 52,020,135 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01852,629,934 - 52,728,049 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01850,428,129 - 50,526,003 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01851,492,196 - 51,591,028 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1851,492,196 - 51,591,026 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01850,688,264 - 50,786,066 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41852,171,662 - 52,271,700 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11852,217,156 - 52,317,193 (+)NCBI
Celera1848,029,393 - 48,127,288 (+)NCBICelera
Cytogenetic Map18q11-q12.1NCBI
GRAMD2B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385126,360,120 - 126,494,364 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5126,360,132 - 126,496,494 (+)EnsemblGRCh38hg38GRCh38
GRCh375125,695,812 - 125,830,056 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365125,787,000 - 125,857,955 (+)NCBINCBI36Build 36hg18NCBI36
Celera5121,652,415 - 121,786,450 (+)NCBICelera
Cytogenetic Map5q23.2NCBI
HuRef5120,886,712 - 121,020,764 (+)NCBIHuRef
CHM1_15125,128,437 - 125,262,497 (+)NCBICHM1_1
T2T-CHM13v2.05126,876,891 - 127,011,484 (+)NCBIT2T-CHM13v2.0
Gramd2b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391856,533,412 - 56,636,864 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1856,533,409 - 56,636,864 (+)EnsemblGRCm39 Ensembl
GRCm381856,387,485 - 56,503,792 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1856,400,337 - 56,503,792 (+)EnsemblGRCm38mm10GRCm38
MGSCv371856,591,786 - 56,663,446 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361856,525,706 - 56,628,208 (+)NCBIMGSCv36mm8
Celera1857,739,584 - 57,814,488 (+)NCBICelera
Cytogenetic Map18D3NCBI
cM Map1830.43NCBI
Gramd2b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555214,219,461 - 4,320,858 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555214,220,325 - 4,320,452 (+)NCBIChiLan1.0ChiLan1.0
GRAMD2B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24121,736,881 - 121,812,321 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15119,736,017 - 119,951,884 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05121,826,628 - 121,897,559 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15127,516,864 - 127,670,221 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5127,547,050 - 127,670,221 (+)Ensemblpanpan1.1panPan2
GRAMD2B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11115,673,819 - 15,784,013 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1115,661,886 - 15,783,064 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1114,466,696 - 14,577,119 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01116,398,568 - 16,509,304 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1116,385,859 - 16,526,341 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11115,130,440 - 15,240,836 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01114,977,002 - 15,087,038 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01115,572,379 - 15,683,305 (+)NCBIUU_Cfam_GSD_1.0
Gramd2b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213138,271,574 - 138,339,891 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365756,352,659 - 6,422,007 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365756,352,626 - 6,421,220 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GRAMD2B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2129,511,088 - 129,619,687 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12129,511,072 - 129,619,690 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22134,840,574 - 134,840,827 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GRAMD2B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12329,366,834 - 29,483,334 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2329,416,060 - 29,482,139 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603448,593,360 - 48,709,851 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gramd2b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477415,154,236 - 15,266,930 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477415,155,485 - 15,267,066 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Gramd2b
759 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:125
Count of miRNA genes:91
Interacting mature miRNAs:116
Transcripts:ENSRNOT00000020570
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331733Bp233Blood pressure QTL 2333.97196arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)182479697779788953Rat
1358358Sradr6Stress Responsive Adrenal Weight QTL 62.49adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)181194429959330563Rat
1331798Bp224Blood pressure QTL 2243.53873arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183135940859796643Rat
2303584Gluco55Glucose level QTL 552blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)184852004483828827Rat
61383Bp47Blood pressure QTL 4717.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)183127168160377755Rat
1331741Bp232Blood pressure QTL 2323.59112arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)182137289383213037Rat
1331742Bp228Blood pressure QTL 2283.88752arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183135940859796643Rat
1331806Bp229Blood pressure QTL 2294.36484arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)184671876357867167Rat
1331736Bp227Blood pressure QTL 2272.791arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)184671876359796643Rat
1331780Bp238Blood pressure QTL 2383.269arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)184671876359796643Rat
1331776Bp225Blood pressure QTL 2252.829arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)183135940859796643Rat
6903359Bp355Blood pressure QTL 3553.6arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)181194454459796478Rat
631518Bw11Body weight QTL 112.8body mass (VT:0001259)body weight (CMO:0000012)183587072380870723Rat
6903345Bp349Blood pressure QTL 3493.9arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)184671893559796478Rat
2313082Bss85Bone structure and strength QTL 850.80.0001long bone metaphysis morphology trait (VT:0000133)tibia midshaft total cross-sectional area (CMO:0001715)181495133759951337Rat
1641923Colcr8Colorectal carcinoma resistance QTL 83.10.0014intestine integrity trait (VT:0010554)poorly differentiated malignant colorectal tumor number (CMO:0002076)182206624252293055Rat
6903347Bp350Blood pressure QTL 3504.4arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183135953059796478Rat
6893683Bw110Body weight QTL 1102.70.002body mass (VT:0001259)body weight (CMO:0000012)184334502283828827Rat
8694366Abfw8Abdominal fat weight QTL 86.380.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)184664067583828827Rat
1331727Bp237Blood pressure QTL 2373.053arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183135940861698465Rat
6903349Bp351Blood pressure QTL 3513.5arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)184671893559796478Rat
2300157Bmd66Bone mineral density QTL 6613.10.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)182896485373964853Rat
738005Anxrr11Anxiety related response QTL 113.4exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)183003981375039813Rat
6903351Bp352Blood pressure QTL 3523.3arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)184671893559796478Rat
631274Sprol1Serum protein level QTL 15.3blood total protein amount (VT:0005567)serum total protein level (CMO:0000661)183139332077209694Rat
9589041Epfw12Epididymal fat weight QTL 1217.080.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)184664067583828827Rat
8694432Bw165Body weight QTL 1653.810.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)184664067583828827Rat
1358193Emca2Estrogen-induced mammary cancer QTL 21.6mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)181800759963571040Rat
2293704Bss35Bone structure and strength QTL 354.590.0002femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)182896485373964853Rat
9589816Gluco68Glucose level QTL 687.250.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)182979296574792965Rat
1331774Bp226Blood pressure QTL 2264.41065arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183135940859796643Rat
2325839Bp348Blood pressure QTL 3480.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)182557098570570985Rat
1600373Mamtr6Mammary tumor resistance QTL 6mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)181927890183218561Rat
2293708Bss46Bone structure and strength QTL 468.80.0001lumbar vertebra morphology trait (VT:0010494)lumbar vertebra cortical cross-sectional area (CMO:0001690)181179151863636873Rat
8694378Bw157Body weight QTL 1573.590.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)182979296574792965Rat
61360EaeyExperimental allergic encephalomyelitis QTL y3nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis duration (CMO:0001424)184698893960377753Rat
2303571Bw92Body weight QTL 923body mass (VT:0001259)body weight (CMO:0000012)184852004483828827Rat
2300177Bmd65Bone mineral density QTL 6519.70.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)182896485373964853Rat
1598826Anxrr20Anxiety related response QTL 203.04body movement coordination trait (VT:0005424)number of rearing movements in an experimental apparatus (CMO:0001752)184143297183828827Rat
1578667Bss21Bone structure and strength QTL 213.5femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)181179151883218561Rat
2303120Mamtr8Mammary tumor resistance QTL 80.001mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)183135940883218561Rat
61429Cia17Collagen induced arthritis QTL 174.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)183135940870263868Rat
61367Iddm4Insulin dependent diabetes mellitus QTL 42.330.0074blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)183819245583192455Rat
2299160Iddm35Insulin dependent diabetes mellitus QTL 352.79blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)18420794160377792Rat
9590318Scort22Serum corticosterone level QTL 227.640.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)182979296574792965Rat
1578661Bss20Bone structure and strength QTL 203.7femur morphology trait (VT:0000559)femoral neck cross-sectional area (CMO:0001697)181179151883218561Rat
1331753Bp231Blood pressure QTL 2313.643arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)181194429952293055Rat
1331754Bp230Blood pressure QTL 2304.61609arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)182979296574792965Rat

Markers in Region
AW061306  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21849,980,896 - 49,980,999 (+)MAPPERmRatBN7.2
Rnor_6.01851,589,970 - 51,590,072NCBIRnor6.0
Rnor_5.01850,785,008 - 50,785,110UniSTSRnor5.0
RGSC_v3.41852,270,642 - 52,270,744UniSTSRGSC3.4
Celera1848,126,230 - 48,126,332UniSTS
Cytogenetic Map18q12.1UniSTS
RH130954  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21849,981,684 - 49,981,877 (+)MAPPERmRatBN7.2
Rnor_6.01851,590,758 - 51,590,950NCBIRnor6.0
Rnor_5.01850,785,796 - 50,785,988UniSTSRnor5.0
RGSC_v3.41852,271,430 - 52,271,622UniSTSRGSC3.4
Celera1848,127,018 - 48,127,210UniSTS
Cytogenetic Map18q12.1UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000020570   ⟹   ENSRNOP00000020570
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1849,884,014 - 49,981,953 (+)Ensembl
Rnor_6.0 Ensembl1851,492,196 - 51,591,026 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000078518   ⟹   ENSRNOP00000074694
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1849,914,662 - 49,981,948 (+)Ensembl
Rnor_6.0 Ensembl1851,523,758 - 51,591,026 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000100538   ⟹   ENSRNOP00000081870
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1849,951,043 - 49,981,953 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000117795   ⟹   ENSRNOP00000095800
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1849,914,689 - 49,981,953 (+)Ensembl
RefSeq Acc Id: NM_001014011   ⟹   NP_001014033
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81852,082,128 - 52,180,056 (+)NCBI
mRatBN7.21849,884,014 - 49,981,955 (+)NCBI
Rnor_6.01851,492,196 - 51,591,028 (+)NCBI
Rnor_5.01850,688,264 - 50,786,066 (+)NCBI
RGSC_v3.41852,171,662 - 52,271,700 (+)RGD
Celera1848,029,393 - 48,127,288 (+)RGD
Sequence:
RefSeq Acc Id: XM_006254748   ⟹   XP_006254810
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81852,112,708 - 52,180,056 (+)NCBI
mRatBN7.21849,914,651 - 49,981,955 (+)NCBI
Rnor_6.01851,523,716 - 51,591,028 (+)NCBI
Rnor_5.01850,688,264 - 50,786,066 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063277299   ⟹   XP_063133369
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81852,112,752 - 52,180,056 (+)NCBI
RefSeq Acc Id: NP_001014033   ⟸   NM_001014011
- UniProtKB: Q5FVG8 (UniProtKB/Swiss-Prot),   A6IX52 (UniProtKB/TrEMBL),   A0A8I5ZT46 (UniProtKB/TrEMBL),   A6IX54 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006254810   ⟸   XM_006254748
- Peptide Label: isoform X1
- UniProtKB: A0A0G2K8Q2 (UniProtKB/TrEMBL),   A6IX53 (UniProtKB/TrEMBL),   A0A8I5ZT46 (UniProtKB/TrEMBL),   A6IX54 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000020570   ⟸   ENSRNOT00000020570
Ensembl Acc Id: ENSRNOP00000074694   ⟸   ENSRNOT00000078518
Ensembl Acc Id: ENSRNOP00000081870   ⟸   ENSRNOT00000100538
Ensembl Acc Id: ENSRNOP00000095800   ⟸   ENSRNOT00000117795
RefSeq Acc Id: XP_063133369   ⟸   XM_063277299
- Peptide Label: isoform X2
- UniProtKB: A0A8I6APU9 (UniProtKB/TrEMBL)
Protein Domains
GRAM

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5FVG8-F1-model_v2 AlphaFold Q5FVG8 1-445 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13700787
Promoter ID:EPDNEW_R11311
Type:multiple initiation site
Name:Gramd3_2
Description:GRAM domain containing 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R11312  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01851,492,100 - 51,492,160EPDNEW
RGD ID:13700805
Promoter ID:EPDNEW_R11312
Type:multiple initiation site
Name:Gramd3_1
Description:GRAM domain containing 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R11311  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01851,523,747 - 51,523,807EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1311016 AgrOrtholog
BioCyc Gene G2FUF-7451 BioCyc
Ensembl Genes ENSRNOG00000015225 Ensembl, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSRNOG00060012701 UniProtKB/Swiss-Prot
  ENSRNOG00065003490 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000020570.7 UniProtKB/Swiss-Prot
  ENSRNOT00000078518.2 UniProtKB/TrEMBL
  ENSRNOT00000100538.1 UniProtKB/TrEMBL
  ENSRNOT00000117795.1 UniProtKB/TrEMBL
  ENSRNOT00060021591 UniProtKB/Swiss-Prot
  ENSRNOT00065004982 UniProtKB/Swiss-Prot
Gene3D-CATH 2.30.29.30 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7321780 IMAGE-MGC_LOAD
InterPro GRAM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GRAM_domain_protein_2B UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PH-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:307288 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:109479 IMAGE-MGC_LOAD
NCBI Gene 307288 ENTREZGENE
PANTHER GRAM DOMAIN-CONTAINING PROTEIN 2B UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GRAM DOMAIN-CONTAINING PROTEIN 2B-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam GRAM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Gramd2b PhenoGen
RatGTEx ENSRNOG00000015225 RatGTEx
  ENSRNOG00060012701 RatGTEx
  ENSRNOG00065003490 RatGTEx
SMART GRAM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2K8Q2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZT46 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6APU9 ENTREZGENE, UniProtKB/TrEMBL
  A6IX52 ENTREZGENE, UniProtKB/TrEMBL
  A6IX53 ENTREZGENE, UniProtKB/TrEMBL
  A6IX54 ENTREZGENE, UniProtKB/TrEMBL
  GRM2B_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-07-06 Gramd2b  GRAM domain containing 2B  Gramd3  GRAM domain containing 3  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Gramd3  GRAM domain containing 3  RGD1311016  similar to RIKEN cDNA 9130427A09  Symbol and Name updated 1299863 APPROVED
2005-12-06 RGD1311016  similar to RIKEN cDNA 9130427A09  RGD1311016_predicted  similar to RIKEN cDNA 9130427A09 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-20 RGD1311016_predicted  similar to RIKEN cDNA 9130427A09 (predicted)  LOC307288_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC307288_predicted  similar to RIKEN cDNA 9130427A09 (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL