Predicted to enable ATP hydrolysis activity and metalloendopeptidase activity. Predicted to be involved in several processes, including calcium import into the mitochondrion; cellular response to glutathione; and proteolysis. Predicted to act upstream of or within several processes, including mitochondrion organization; nervous system development; and righting reflex. Predicted to be located in mitochondrion. Predicted to be part of m-AAA complex. Predicted to be active in mitochondrial inner membrane. Human ortholog(s) of this gene implicated in optic atrophy 12; spastic ataxia; spastic ataxia 5; and spinocerebellar ataxia type 28. Orthologous to human AFG3L2 (AFG3 like matrix AAA peptidase subunit 2); INTERACTS WITH 2,6-dinitrotoluene; 3-chloropropane-1,2-diol; 4-amino-2,6-dinitrotoluene.
AFG3 ATPase family gene 3-like 2; AFG3 ATPase family gene 3-like 2 (S. cerevisiae); AFG3 ATPase family member 3-like 2; AFG3 ATPase family member 3-like 2 (S. cerevisiae); AFG3(ATPase family gene 3)-like 2; AFG3(ATPase family gene 3)-like 2 (yeast); AFG3-like AAA ATPase 2; AFG3-like protein 2; LOC307350; MGC109579
[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of AFG3L2 mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of AFG3L2 mRNA
[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of AFG3L2 mRNA
[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of AFG3L2 mRNA
[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of AFG3L2 mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of AFG3L2 mRNA
[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of AFG3L2 mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of AFG3L2 mRNA
[LDN 193189 co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide co-treated with FGF2 protein] results in decreased expression of AFG3L2 protein