Megf10 (multiple EGF-like domains 10) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Megf10 (multiple EGF-like domains 10) Rattus norvegicus
Analyze
Symbol: Megf10
Name: multiple EGF-like domains 10
RGD ID: 735084
Description: Predicted to enable Notch binding activity; complement component C1q complex binding activity; and scavenger receptor activity. Predicted to be involved in several processes, including myoblast development; positive regulation of myoblast proliferation; and skeletal muscle satellite cell proliferation. Predicted to act upstream of or within apoptotic process involved in development; engulfment of apoptotic cell; and recognition of apoptotic cell. Predicted to be located in phagocytic cup. Human ortholog(s) of this gene implicated in congenital myopathy 10B and early-onset myopathy-areflexia-respiratory distress-dysphagia syndrome. Orthologous to human MEGF10 (multiple EGF like domains 10); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; ammonium chloride.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: multiple epidermal growth factor-like domains protein 10
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81852,803,292 - 52,953,431 (+)NCBIGRCr8
mRatBN7.21850,605,231 - 50,755,441 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1850,605,656 - 50,754,456 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1852,694,133 - 52,797,033 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01853,409,354 - 53,512,382 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01851,200,013 - 51,302,914 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01852,215,652 - 52,366,212 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1852,215,682 - 52,366,238 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01851,403,811 - 51,554,336 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41852,948,935 - 53,051,823 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11853,052,380 - 53,072,113 (+)NCBI
Celera1848,786,696 - 48,889,249 (+)NCBICelera
Cytogenetic Map18q12.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


References

References - curated
# Reference Title Reference Citation
1. A monoclonal autoantibody which promotes central nervous system remyelination is highly polyreactive to multiple known and novel antigens. Asakura K, etal., J Neuroimmunol 1996 Mar;65(1):11-9.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:17205124   PMID:17643423   PMID:18056409   PMID:19915564   PMID:22101682   PMID:22407321   PMID:27170117   PMID:28498977  


Genomics

Comparative Map Data
Megf10
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81852,803,292 - 52,953,431 (+)NCBIGRCr8
mRatBN7.21850,605,231 - 50,755,441 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1850,605,656 - 50,754,456 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1852,694,133 - 52,797,033 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01853,409,354 - 53,512,382 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01851,200,013 - 51,302,914 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01852,215,652 - 52,366,212 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1852,215,682 - 52,366,238 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01851,403,811 - 51,554,336 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41852,948,935 - 53,051,823 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11853,052,380 - 53,072,113 (+)NCBI
Celera1848,786,696 - 48,889,249 (+)NCBICelera
Cytogenetic Map18q12.1NCBI
MEGF10
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385127,229,300 - 127,461,222 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5127,290,796 - 127,465,737 (+)EnsemblGRCh38hg38GRCh38
GRCh375126,626,488 - 126,796,914 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365126,654,514 - 126,824,807 (+)NCBINCBI36Build 36hg18NCBI36
Celera5122,757,239 - 122,927,674 (+)NCBICelera
Cytogenetic Map5q23.2NCBI
HuRef5121,817,526 - 121,988,151 (+)NCBIHuRef
CHM1_15126,059,059 - 126,229,496 (+)NCBICHM1_1
T2T-CHM13v2.05127,749,142 - 127,981,009 (+)NCBIT2T-CHM13v2.0
Megf10
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391857,266,162 - 57,430,539 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1857,266,162 - 57,430,539 (+)EnsemblGRCm39 Ensembl
GRCm381857,133,090 - 57,297,467 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1857,133,090 - 57,297,467 (+)EnsemblGRCm38mm10GRCm38
MGSCv371857,292,744 - 57,457,121 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361857,258,844 - 57,422,835 (+)NCBIMGSCv36mm8
Celera1858,443,454 - 58,608,465 (+)NCBICelera
Cytogenetic Map18D3NCBI
cM Map1831.5NCBI
Megf10
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955415335,012 - 513,891 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955415393,642 - 513,157 (+)NCBIChiLan1.0ChiLan1.0
MEGF10
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24122,534,832 - 122,770,730 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15120,674,719 - 120,910,289 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05122,639,155 - 122,877,324 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15128,466,095 - 128,657,845 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5128,466,095 - 128,641,043 (+)Ensemblpanpan1.1panPan2
MEGF10
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11116,359,648 - 16,574,882 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1116,378,669 - 16,617,335 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1115,047,444 - 15,360,462 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01116,981,258 - 17,301,745 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1116,940,314 - 17,349,743 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11115,711,146 - 16,024,958 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01115,557,940 - 15,871,023 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01116,155,094 - 16,474,941 (+)NCBIUU_Cfam_GSD_1.0
Megf10
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213139,012,245 - 139,182,163 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936504586,190 - 756,255 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936504634,167 - 753,438 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MEGF10
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2130,189,556 - 130,401,077 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12130,226,222 - 130,403,960 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22135,524,848 - 135,686,689 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MEGF10
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12330,028,154 - 30,405,033 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2330,234,489 - 30,404,996 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603447,643,480 - 48,026,869 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Megf10
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477414,153,687 - 14,355,406 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477414,147,412 - 14,354,886 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Megf10
977 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:451
Count of miRNA genes:255
Interacting mature miRNAs:303
Transcripts:ENSRNOT00000037901
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2299160Iddm35Insulin dependent diabetes mellitus QTL 352.79blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)18420794160377792Rat
2293708Bss46Bone structure and strength QTL 468.80.0001lumbar vertebra morphology trait (VT:0010494)lumbar vertebra cortical cross-sectional area (CMO:0001690)181179151863636873Rat
1578661Bss20Bone structure and strength QTL 203.7femur morphology trait (VT:0000559)femoral neck cross-sectional area (CMO:0001697)181179151883218561Rat
1578667Bss21Bone structure and strength QTL 213.5femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)181179151883218561Rat
1331753Bp231Blood pressure QTL 2313.643arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)181194429952293055Rat
1358358Sradr6Stress Responsive Adrenal Weight QTL 62.49adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)181194429959330563Rat
6903359Bp355Blood pressure QTL 3553.6arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)181194454459796478Rat
2313082Bss85Bone structure and strength QTL 850.80.0001long bone metaphysis morphology trait (VT:0000133)tibia midshaft total cross-sectional area (CMO:0001715)181495133759951337Rat
1358193Emca2Estrogen-induced mammary cancer QTL 21.6mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)181800759963571040Rat
1600373Mamtr6Mammary tumor resistance QTL 6mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)181927890183218561Rat
1331741Bp232Blood pressure QTL 2323.59112arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)182137289383213037Rat
1641923Colcr8Colorectal carcinoma resistance QTL 83.10.0014intestine integrity trait (VT:0010554)poorly differentiated malignant colorectal tumor number (CMO:0002076)182206624252293055Rat
1331733Bp233Blood pressure QTL 2333.97196arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)182479697779788953Rat
2325839Bp348Blood pressure QTL 3480.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)182557098570570985Rat
2293704Bss35Bone structure and strength QTL 354.590.0002femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)182896485373964853Rat
2300157Bmd66Bone mineral density QTL 6613.10.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)182896485373964853Rat
2300177Bmd65Bone mineral density QTL 6519.70.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)182896485373964853Rat
9589816Gluco68Glucose level QTL 687.250.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)182979296574792965Rat
8694378Bw157Body weight QTL 1573.590.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)182979296574792965Rat
9590318Scort22Serum corticosterone level QTL 227.640.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)182979296574792965Rat
1331754Bp230Blood pressure QTL 2304.61609arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)182979296574792965Rat
738005Anxrr11Anxiety related response QTL 113.4exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)183003981375039813Rat
61383Bp47Blood pressure QTL 4717.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)183127168160377755Rat
1331742Bp228Blood pressure QTL 2283.88752arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183135940859796643Rat
1331774Bp226Blood pressure QTL 2264.41065arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183135940859796643Rat
1331776Bp225Blood pressure QTL 2252.829arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)183135940859796643Rat
1331798Bp224Blood pressure QTL 2243.53873arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183135940859796643Rat
1331727Bp237Blood pressure QTL 2373.053arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183135940861698465Rat
61429Cia17Collagen induced arthritis QTL 174.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)183135940870263868Rat
2303120Mamtr8Mammary tumor resistance QTL 80.001mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)183135940883218561Rat
6903347Bp350Blood pressure QTL 3504.4arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183135953059796478Rat
631274Sprol1Serum protein level QTL 15.3blood total protein amount (VT:0005567)serum total protein level (CMO:0000661)183139332077209694Rat
631518Bw11Body weight QTL 112.8body mass (VT:0001259)body weight (CMO:0000012)183587072380870723Rat
61367Iddm4Insulin dependent diabetes mellitus QTL 42.330.0074blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)183819245583192455Rat
1598826Anxrr20Anxiety related response QTL 203.04body movement coordination trait (VT:0005424)number of rearing movements in an experimental apparatus (CMO:0001752)184143297183828827Rat
6893683Bw110Body weight QTL 1102.70.002body mass (VT:0001259)body weight (CMO:0000012)184334502283828827Rat
8694366Abfw8Abdominal fat weight QTL 86.380.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)184664067583828827Rat
8694432Bw165Body weight QTL 1653.810.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)184664067583828827Rat
9589041Epfw12Epididymal fat weight QTL 1217.080.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)184664067583828827Rat
1331806Bp229Blood pressure QTL 2294.36484arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)184671876357867167Rat
1331736Bp227Blood pressure QTL 2272.791arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)184671876359796643Rat
1331780Bp238Blood pressure QTL 2383.269arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)184671876359796643Rat
6903345Bp349Blood pressure QTL 3493.9arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)184671893559796478Rat
6903349Bp351Blood pressure QTL 3513.5arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)184671893559796478Rat
6903351Bp352Blood pressure QTL 3523.3arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)184671893559796478Rat
61360EaeyExperimental allergic encephalomyelitis QTL y3nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis duration (CMO:0001424)184698893960377753Rat
2303571Bw92Body weight QTL 923body mass (VT:0001259)body weight (CMO:0000012)184852004483828827Rat
2303584Gluco55Glucose level QTL 552blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)184852004483828827Rat
7411719Strs5Sensitivity to stroke QTL 59.4cerebrum integrity trait (VT:0010549)percentage of study population developing cerebrovascular lesions during a period of time (CMO:0000932)184999995865845095Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 1 1 52 5 1
Low 2 33 7 4 5 4 7 10 22 14 31 9 7
Below cutoff 1 10 26 13 14 13 10 5 2

Sequence


RefSeq Acc Id: ENSRNOT00000037901   ⟹   ENSRNOP00000036049
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1850,605,656 - 50,754,456 (+)Ensembl
Rnor_6.0 Ensembl1852,215,682 - 52,366,238 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000114483   ⟹   ENSRNOP00000076780
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1850,605,656 - 50,697,297 (+)Ensembl
RefSeq Acc Id: NM_001100657   ⟹   NP_001094127
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81852,847,781 - 52,950,675 (+)NCBI
mRatBN7.21850,649,725 - 50,752,618 (+)NCBI
Rnor_6.01852,260,507 - 52,363,389 (+)NCBI
Rnor_5.01851,403,811 - 51,554,336 (+)NCBI
RGSC_v3.41852,948,935 - 53,051,823 (+)RGD
Celera1848,786,696 - 48,889,249 (+)RGD
Sequence:
RefSeq Acc Id: XM_006254747   ⟹   XP_006254809
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81852,803,293 - 52,953,431 (+)NCBI
mRatBN7.21850,605,231 - 50,755,441 (+)NCBI
Rnor_6.01852,215,652 - 52,366,212 (+)NCBI
Rnor_5.01851,403,811 - 51,554,336 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039096646   ⟹   XP_038952574
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81852,803,292 - 52,953,431 (+)NCBI
mRatBN7.21850,605,231 - 50,755,441 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001094127 (Get FASTA)   NCBI Sequence Viewer  
  XP_006254809 (Get FASTA)   NCBI Sequence Viewer  
  XP_038952574 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAB05844 (Get FASTA)   NCBI Sequence Viewer  
  EDM14505 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000036049
  ENSRNOP00000036049.4
  ENSRNOP00000076780.1
RefSeq Acc Id: NP_001094127   ⟸   NM_001100657
- Peptide Label: precursor
- UniProtKB: F1MAP4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006254809   ⟸   XM_006254747
- Peptide Label: isoform X1
- UniProtKB: F1MAP4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000036049   ⟸   ENSRNOT00000037901
RefSeq Acc Id: XP_038952574   ⟸   XM_039096646
- Peptide Label: isoform X1
- UniProtKB: F1MAP4 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000076780   ⟸   ENSRNOT00000114483
Protein Domains
EGF-like   EMI

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F1MAP4-F1-model_v2 AlphaFold F1MAP4 1-1145 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:735084 AgrOrtholog
BioCyc Gene G2FUF-7425 BioCyc
Ensembl Genes ENSRNOG00000013674 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000037901.7 UniProtKB/TrEMBL
  ENSRNOT00000114483.1 UniProtKB/TrEMBL
Gene3D-CATH Laminin UniProtKB/TrEMBL
  Tie2 ligand-binding domain superfamily UniProtKB/TrEMBL
InterPro EGF-like_reg_CS UniProtKB/TrEMBL
  EGF_3 UniProtKB/TrEMBL
  EGF_laminin UniProtKB/TrEMBL
  EMI_domain UniProtKB/TrEMBL
KEGG Report rno:291445 UniProtKB/TrEMBL
NCBI Gene 291445 ENTREZGENE
PANTHER DELTA-RELATED UniProtKB/TrEMBL
  PLATELET ENDOTHELIAL AGGREGATION RECEPTOR 1 UniProtKB/TrEMBL
Pfam EMI UniProtKB/TrEMBL
  hEGF UniProtKB/TrEMBL
  Laminin_EGF UniProtKB/TrEMBL
PhenoGen Megf10 PhenoGen
PRINTS EGFLAMININ UniProtKB/TrEMBL
PROSITE EGF_1 UniProtKB/TrEMBL
  EGF_2 UniProtKB/TrEMBL
  EGF_3 UniProtKB/TrEMBL
  EMI UniProtKB/TrEMBL
RatGTEx ENSRNOG00000013674 RatGTEx
SMART EGF UniProtKB/TrEMBL
  EGF_Lam UniProtKB/TrEMBL
UniProt A0A8I5Y0D5_RAT UniProtKB/TrEMBL
  A6IX74_RAT UniProtKB/TrEMBL
  F1MAP4 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-03-06 Megf10  multiple EGF-like domains 10  Megf10  Megf10 protein  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-07-08 Megf10  Megf10 protein      Symbol and Name status set to approved 1299863 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_other a partial cDNA clone was isolated by screening a library with a mouse monoclonal antibody which was raised against a spinal cord extract and which had been determined to stimulate remyelination when injected into Theiler's virus-infected mice 1299635