Gene: Smad2 (SMAD family member 2) Rattus norvegicus
Symbol: Smad2
Name: SMAD family member 2
Description: ENCODES a protein that exhibits transcription factor binding; activating transcription factor binding (ortholog); chromatin binding (ortholog); INVOLVED IN adrenal gland development; negative regulation of cell proliferation; positive regulation of transcription by RNA polymerase II; PARTICIPATES IN transforming growth factor-beta Smad dependent signaling pathway; altered transforming growth factor-beta Smad dependent signaling pathway; colorectal cancer pathway; ASSOCIATED WITH Carcinoma, Hepatocellular; Hypoglossal Nerve Injuries; Myocardial Infarction; FOUND IN cytoplasm; nucleus; protein-containing complex; INTERACTS WITH 2-acetamidofluorene; 2-amino-2-deoxy-D-galactopyranose; 2-methoxyethanol
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: MAD (mothers against decapentaplegic Drosophila) homolog 2; MAD (mothers against decapentaplegic, Drosophila) homolog 2; MAD homolog 2; MAD homolog 2 (Drosophila); mad-related protein 2; Madh2; MGC156656; mothers against decapentaplegic homolog 2; mothers against DPP homolog 2; SMAD 2
Homo sapiens (human) : SMAD2 (SMAD family member 2)  HGNC  Alliance
Mus musculus (house mouse) : Smad2 (SMAD family member 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Smad2 (SMAD family member 2)
Pan paniscus (bonobo/pygmy chimpanzee) : SMAD2 (SMAD family member 2)
Canis lupus familiaris (dog) : SMAD2 (SMAD family member 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Smad2 (SMAD family member 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01872,550,107 - 72,612,078 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01871,672,879 - 71,735,128 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41873,180,520 - 73,241,707 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11873,253,792 - 73,314,980 (+)NCBI
Celera1868,381,756 - 68,443,610 (+)NCBICelera
Cytogenetic Map18q12.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Smad2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3031
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2018-04-10
Status: ACTIVE