Strain Report - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Strain Registration

Strain: SS.LEW-(D18Rat61-D18Rat45)/Ayd

Symbol: SS.LEW-(D18Rat61-D18Rat45)/Ayd
Strain: SS.LEW-(D18Rat61-D18Rat45)
Substrain: Ayd
RGD ID: 2301386
Citation ID: RRID:RGD_2301386
Ontology ID: RS:0001659
Also Known As: C18S.L2;DSS X LEW-(D18Rat61-D18Rat45)/Lt;SS.LEW-(D18Rat61-D18Rat45)/Ayd; SS.LEW-(D18Rat55-D18Rat1)/Ayd; SS.LEW-(D18Rat55-D18Rat1)/Ayd; SS.LEW-(D18Rat61-D18Rat45)/Ayd
Type: congenic
Available Source: Not Available
Origination: Research Centre-CHUM, Montreal, Quebec, Canada
Description: SS/Jr and LEW/Crlc were backcrossed for 5 generations, then BC5 rat was mated with LEW/Crlc to produce the desired congenic strain
Last Known Status: Unknown
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21858,805,687 - 74,055,742RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01860,971,508 - 77,212,332RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01860,167,906 - 76,318,715RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.41861,571,526 - 77,511,190RGD_MAPPER_PIPELINERGSC3.4





References

References - curated
# Reference Title Reference Citation
1. A loss of genome buffering capacity of Dahl salt-sensitive model to modulate blood pressure as a cause of hypertension. Charron S, etal., Hum Mol Genet. 2005 Dec 15;14(24):3877-84. Epub 2005 Nov 8.
2. alpha-Kinase 2 is a novel candidate gene for inherited hypertension in Dahl rats. Chauvet C, etal., J Hypertens. 2011 Jul;29(7):1320-6. doi: 10.1097/HJH.0b013e32834705e4.
3. Combining distinctive and novel loci doubles BP reduction, reverses diastolic dysfunction and mitigates LV hypertrophy. Crespo K, etal., J Hypertens. 2013 May;31(5):927-35. doi: 10.1097/HJH.0b013e32835edc7e.
4. Distinct quantitative trait loci for kidney, cardiac, and aortic mass dissociated from and associated with blood pressure in Dahl congenic rats. Duong C, etal., Mamm Genome. 2006 Dec;17(12):1147-61. Epub 2006 Dec 1.
5. RGD Strain RSO annotation pipeline RGD Automated Pipelines

Region

Position Markers

Flank 1 / 1 (D18Rat61)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21858,805,687 - 58,805,936 (+)MAPPER
Rnor_6.01860,971,508 - 60,971,754NCBI
Rnor_5.01860,167,906 - 60,168,152UniSTS
RGSC_v3.41861,571,527 - 61,571,773UniSTS
RGSC_v3.41861,571,526 - 61,571,773RGD
RGSC_v3.11861,644,728 - 61,644,974RGD
Celera1856,934,591 - 56,934,837UniSTS
RH 3.4 Map18595.5RGD
RH 3.4 Map18595.5UniSTS
RH 2.0 Map18321.4RGD
SHRSP x BN Map1833.1899RGD
FHH x ACI Map1843.03RGD
Cytogenetic Map18q12.1UniSTS

Flank 2 / 1 (D18Rat45)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21874,055,619 - 74,055,742 (+)MAPPER
Rnor_6.01877,212,212 - 77,212,332NCBI
Rnor_5.01876,318,595 - 76,318,715UniSTS
RGSC_v3.41877,510,855 - 77,510,975UniSTS
RGSC_v3.41877,510,828 - 77,511,190RGD
RGSC_v3.11877,584,128 - 77,584,248RGD
Celera1872,713,123 - 72,713,243UniSTS
RH 3.4 Map18794.7RGD
RH 3.4 Map18794.7UniSTS
RH 2.0 Map18106.0RGD
SHRSP x BN Map1847.8399RGD
FHH x ACI Map1858.5499RGD
Cytogenetic Map18q12.3UniSTS
Strain QTL Data
Symbol Name Trait
Am18 Aortic mass QTL 18 aorta mass   (VT:0002845)    
Bp319 Blood pressure QTL 319 arterial blood pressure trait   (VT:2000000)    
Bw187 Body weight QTL 187 body mass   (VT:0001259)    
Cm122 Cardiac mass QTL 122 heart mass   (VT:0007028)    
Cm123 Cardiac mass QTL 123 heart left ventricle mass   (VT:0007031)    
Cm124 Cardiac mass QTL 124 heart right ventricle mass   (VT:0007033)    
Kidm71 Kidney mass QTL 71 kidney mass   (VT:0002707)    

Additional Information