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Gene: DCC (DCC netrin 1 receptor) Homo sapiens
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Symbol: DCC
Name: DCC netrin 1 receptor
Description: Predicted to have transmembrane signaling receptor activity. Involved in regulation of neuron death. Predicted to localize to the cytosol and plasma membrane. Implicated in congenital mirror movement disorder; esophageal cancer; and esophagus squamous cell carcinoma.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: colorectal cancer suppressor; colorectal tumor suppressor; CRC18; CRCR1; deleted in colorectal cancer protein; deleted in colorectal carcinoma; HGPPS2; IGDCC1; immunoglobulin superfamily DCC subclass member 1; immunoglobulin superfamily, DCC subclass, member 1; MRMV1; netrin receptor DCC; NTN1R1; putative colorectal tumor suppressor; tumor suppressor protein DCC
Orthologs:
Mus musculus (house mouse) : Dcc (deleted in colorectal carcinoma)  MGI  Alliance
Rattus norvegicus (Norway rat) : Dcc (DCC netrin 1 receptor)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dcc (DCC netrin 1 receptor)
Pan paniscus (bonobo/pygmy chimpanzee) : DCC (DCC netrin 1 receptor)
Canis lupus familiaris (dog) : DCC (DCC netrin 1 receptor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dcc (DCC netrin 1 receptor)
Sus scrofa (pig) : DCC (DCC netrin 1 receptor)
Chlorocebus sabaeus (green monkey) : DCC (DCC netrin 1 receptor)
Heterocephalus glaber (naked mole-rat) : Dcc (DCC netrin 1 receptor)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl1852,340,197 - 53,535,903 (+)Ensembl
GRCh381852,340,172 - 53,535,899 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371849,866,542 - 51,062,273 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361848,120,569 - 49,311,780 (+)NCBINCBI36hg18NCBI36
Build 341848,121,155 - 49,311,286NCBI
Celera1846,722,385 - 47,918,339 (+)NCBI
Cytogenetic Map18q21.2NCBI
HuRef1846,722,887 - 47,917,133 (+)NCBIHuRef
CHM1_11849,861,521 - 51,057,237 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on DCC
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 731288
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.