Gene: Aire (autoimmune regulator) Rattus norvegicus
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Symbol: Aire
Name: autoimmune regulator
Description: ENCODES a protein that exhibits chromatin binding (ortholog); histone binding (ortholog); identical protein binding (ortholog); INVOLVED IN central tolerance induction to self antigen (ortholog); chemokine production (ortholog); humoral immune response (ortholog); PARTICIPATES IN primary immunodeficiency pathway; ubiquitin/proteasome degradation pathway; ASSOCIATED WITH autistic disorder (ortholog); autoimmune polyendocrine syndrome (ortholog); autoimmune polyendocrine syndrome type 1 (ortholog); FOUND IN cytoplasm (ortholog); nuclear body (ortholog); nucleus (ortholog); INTERACTS WITH acrylamide; bisphenol A; cadmium dichloride
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy); LOC294328
Orthologs:
Homo sapiens (human) : AIRE (autoimmune regulator)  HGNC  Alliance
Mus musculus (house mouse) : Aire (autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy))  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Aire (autoimmune regulator)
Pan paniscus (bonobo/pygmy chimpanzee) : AIRE (autoimmune regulator)
Canis lupus familiaris (dog) : AIRE (autoimmune regulator)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Aire (autoimmune regulator)
Sus scrofa (pig) : AIRE (autoimmune regulator)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02011,365,630 - 11,380,636 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02013,535,776 - 13,550,486 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42010,980,031 - 10,996,102 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12010,980,315 - 10,996,140 (+)NCBI
Celera2012,141,888 - 12,156,863 (+)NCBICelera
Cytogenetic Map20p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Aire
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1311139
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-01-30
Status: ACTIVE