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Gene: Sugp1 (SURP and G patch domain containing 1) Rattus norvegicus
Analyze
Symbol:
Sugp1
Name:
SURP and G patch domain containing 1
RGD ID:
1310496
Description:
Predicted to enable RNA binding activity. Predicted to be involved in RNA splicing and mRNA processing. Predicted to be part of spliceosomal complex. Predicted to be active in nucleoplasm. Orthologous to human SUGP1 (SURP and G-patch domain containing 1); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type:
protein-coding
RefSeq Status:
PROVISIONAL
Previously known as:
LOC290666; Sf4; splicing factor 4; SURP and G-patch domain-containing protein 1
RGD Orthologs
Alliance Genes
More Info
more info ...
More Info
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Homo sapiens (human):
SUGP1 (SURP and G-patch domain containing 1)
HGNC
Ensembl, HomoloGene, Inparanoid, NCBI, Panther, PhylomeDB
Mus musculus (house mouse):
Sugp1 (SURP and G patch domain containing 1)
HGNC
NCBI, HomoloGene, Inparanoid, Panther, PhylomeDB, Ensembl
Chinchilla lanigera (long-tailed chinchilla):
Sugp1 (SURP and G-patch domain containing 1)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):
SUGP1 (SURP and G-patch domain containing 1)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Canis lupus familiaris (dog):
SUGP1 (SURP and G-patch domain containing 1)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):
Sugp1 (SURP and G-patch domain containing 1)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Sus scrofa (pig):
SUGP1 (SURP and G-patch domain containing 1)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):
SUGP1 (SURP and G-patch domain containing 1)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):
Sugp1 (SURP and G-patch domain containing 1)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Alliance orthologs 3
Homo sapiens (human):
SUGP1 (SURP and G-patch domain containing 1)
Alliance
DIOPT (Ensembl Compara|HGNC|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Mus musculus (house mouse):
Sugp1 (SURP and G patch domain containing 1)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Danio rerio (zebrafish):
sugp1 (SURP and G patch domain containing 1)
Alliance
DIOPT (Ensembl Compara|OrthoFinder|OrthoInspector|SonicParanoid)
Drosophila melanogaster (fruit fly):
CG31550
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OrthoFinder|OrthoInspector|PANTHER|SonicParanoid)
Allele / Splice:
Sf4Tn(sb-T2/Bart3)2.264Mcwi
Genetic Models:
F344-Sf4Tn(sb-T2/Bart3)2.264Mcwi
Latest Assembly:
mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl mRatBN7.2 16 19,352,659 - 19,383,533 (-) NCBI mRatBN7.2 mRatBN7.2 Ensembl 16 19,351,793 - 19,383,756 (-) Ensembl Rnor_6.0 16 21,100,923 - 21,131,795 (-) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 16 21,100,924 - 21,131,795 (-) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 16 21,016,310 - 21,047,301 (-) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 Rnor_5.0 16 20,950,430 - 20,985,149 (-) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 16 19,835,921 - 19,866,795 (-) NCBI RGSC3.4 rn4 RGSC3.4 RGSC_v3.1 16 19,835,919 - 19,866,793 (-) NCBI Celera 16 19,541,347 - 19,572,611 (-) NCBI Celera Cytogenetic Map 16 p14 NCBI
JBrowse:
View Region in Genome Browser (JBrowse)
Model
Only show annotations with direct experimental evidence (0 objects hidden)
1,2-dimethylhydrazine decreases expression ISO RGD:1321430 6480464 1, 2-Dimethylhydrazine results in decreased expression of SUGP1 mRNA CTD PMID:22206623 17alpha-ethynylestradiol multiple interactions ISO RGD:1321430 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of SUGP1 mRNA CTD PMID:17942748 17alpha-ethynylestradiol decreases expression EXP 6480464 Ethinyl Estradiol results in decreased expression of SUGP1 mRNA CTD PMID:29097150 17alpha-ethynylestradiol increases expression ISO RGD:1321430 6480464 Ethinyl Estradiol results in increased expression of SUGP1 mRNA CTD PMID:17942748 2,2',4,4'-Tetrabromodiphenyl ether affects expression ISO RGD:1321430 6480464 2 more ... CTD PMID:30294300 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:1321430 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of SUGP1 mRNA CTD PMID:17942748 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of SUGP1 mRNA CTD PMID:31511937 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:1321430 6480464 Tetrachlorodibenzodioxin affects the expression of SUGP1 mRNA CTD PMID:21570461 2,4-dinitrotoluene affects expression EXP 6480464 2, 4-dinitrotoluene affects the expression of SUGP1 mRNA CTD PMID:21346803 3,4-methylenedioxymethamphetamine increases expression ISO RGD:1321430 6480464 N-Methyl-3, 4-methylenedioxyamphetamine results in increased expression of SUGP1 mRNA CTD PMID:20188158 aflatoxin B1 decreases methylation ISO RGD:1321429 6480464 Aflatoxin B1 results in decreased methylation of SUGP1 intron CTD PMID:30157460 Aflatoxin B2 alpha decreases methylation ISO RGD:1321429 6480464 aflatoxin B2 results in decreased methylation of SUGP1 intron CTD PMID:30157460 aristolochic acid increases expression ISO RGD:1321429 6480464 aristolochic acid I results in increased expression of SUGP1 mRNA CTD PMID:33212167 atrazine decreases expression ISO RGD:1321429 6480464 Atrazine results in decreased expression of SUGP1 mRNA CTD PMID:22378314 benzo[e]pyrene decreases methylation ISO RGD:1321429 6480464 benzo(e)pyrene results in decreased methylation of SUGP1 intron CTD PMID:30157460 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of SUGP1 mRNA CTD PMID:25181051 bisphenol A multiple interactions ISO RGD:1321429 6480464 [bisphenol A co-treated with Fulvestrant] results in increased methylation of SUGP1 gene CTD PMID:31601247 bisphenol A decreases expression ISO RGD:1321430 6480464 bisphenol A results in decreased expression of SUGP1 mRNA CTD PMID:33221593 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of SUGP1 mRNA CTD PMID:30816183 , PMID:32528016 bisphenol F multiple interactions ISO RGD:1321429 6480464 [bisphenol F co-treated with Fulvestrant] results in increased methylation of SUGP1 gene CTD PMID:31601247 casticin decreases expression ISO RGD:1321430 6480464 casticin results in decreased expression of SUGP1 mRNA CTD PMID:28444820 copper(II) sulfate decreases expression ISO RGD:1321429 6480464 Copper Sulfate results in decreased expression of SUGP1 mRNA CTD PMID:19549813 dibutyl phthalate decreases expression ISO RGD:1321430 6480464 Dibutyl Phthalate results in decreased expression of SUGP1 mRNA CTD PMID:21266533 doxorubicin decreases expression ISO RGD:1321429 6480464 Doxorubicin results in decreased expression of SUGP1 mRNA CTD PMID:29803840 enzyme inhibitor multiple interactions ISO RGD:1321429 6480464 [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of SUGP1 protein CTD PMID:23301498 ethanol affects expression ISO RGD:1321430 6480464 Ethanol affects the expression of SUGP1 mRNA CTD PMID:30319688 flutamide increases expression EXP 6480464 Flutamide results in increased expression of SUGP1 mRNA CTD PMID:24136188 fulvestrant multiple interactions ISO RGD:1321429 6480464 [bisphenol A co-treated with Fulvestrant] results in increased methylation of SUGP1 gene, [bisphenol F co-treated with Fulvestrant] results in increased methylation of SUGP1 gene CTD PMID:31601247 hexane decreases methylation EXP 6480464 n-hexane results in decreased methylation of SUGP1 promoter CTD PMID:23740543 hydrogen peroxide multiple interactions ISO RGD:1321430 6480464 N-(oxo-5 more ... CTD PMID:31494107 lead(0) decreases expression ISO RGD:1321429 6480464 Lead results in decreased expression of SUGP1 mRNA CTD PMID:19921347 lead(0) affects expression ISO RGD:1321429 6480464 Lead affects the expression of SUGP1 mRNA CTD PMID:28903495 lead(2+) decreases expression ISO RGD:1321429 6480464 Lead results in decreased expression of SUGP1 mRNA CTD PMID:19921347 lead(2+) affects expression ISO RGD:1321429 6480464 Lead affects the expression of SUGP1 mRNA CTD PMID:28903495 leflunomide decreases expression ISO RGD:1321429 6480464 leflunomide results in decreased expression of SUGP1 mRNA CTD PMID:28988120 methapyrilene decreases methylation ISO RGD:1321429 6480464 Methapyrilene results in decreased methylation of SUGP1 intron CTD PMID:30157460 methidathion increases expression ISO RGD:1321430 6480464 methidathion results in increased expression of SUGP1 mRNA CTD PMID:34813904 paracetamol affects expression ISO RGD:1321430 6480464 Acetaminophen affects the expression of SUGP1 mRNA CTD PMID:17562736 PCB138 decreases expression EXP 6480464 2 more ... CTD PMID:23829299 quercitrin increases expression ISO RGD:1321429 6480464 quercitrin results in increased expression of SUGP1 mRNA CTD PMID:25193878 sunitinib decreases expression ISO RGD:1321429 6480464 Sunitinib results in decreased expression of SUGP1 mRNA CTD PMID:31533062 temozolomide increases expression ISO RGD:1321429 6480464 Temozolomide results in increased expression of SUGP1 mRNA CTD PMID:31758290 trichostatin A affects expression ISO RGD:1321429 6480464 trichostatin A affects the expression of SUGP1 mRNA CTD PMID:28542535 urethane increases expression ISO RGD:1321429 6480464 Urethane results in increased expression of SUGP1 mRNA CTD PMID:28818685 valproic acid increases methylation ISO RGD:1321429 6480464 Valproic Acid results in increased methylation of SUGP1 gene CTD PMID:29154799
1,2-dimethylhydrazine (ISO) 17alpha-ethynylestradiol (EXP,ISO) 2,2',4,4'-Tetrabromodiphenyl ether (ISO) 2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO) 2,4-dinitrotoluene (EXP) 3,4-methylenedioxymethamphetamine (ISO) aflatoxin B1 (ISO) Aflatoxin B2 alpha (ISO) aristolochic acid (ISO) atrazine (ISO) benzo[e]pyrene (ISO) bisphenol A (EXP,ISO) bisphenol F (ISO)
References
Additional References at PubMed
Genomics
QTLs in Region (mRatBN7.2)
1600369 Hcas8 Hepatocarcinoma susceptibility QTL 8 liver integrity trait (VT:0010547) liver tumorous lesion number (CMO:0001068) 16 1 22477621 Rat 631830 Alc7 Alcohol consumption QTL 7 2.9 consumption behavior trait (VT:0002069) ethanol drink intake rate (CMO:0001407) 16 1 26727669 Rat 634355 Rends4 Renal damage susceptibility QTL 4 0.05 kidney blood vessel morphology trait (VT:0000530) organ lesion measurement (CMO:0000677) 16 1 26727669 Rat 1582235 Insul8 Insulin level QTL 8 3.3 0.0063 blood insulin amount (VT:0001560) calculated serum insulin level (CMO:0000359) 16 1 26727669 Rat 9590151 Scort8 Serum corticosterone level QTL 8 8.45 0.001 blood corticosterone amount (VT:0005345) plasma corticosterone level (CMO:0001173) 16 1 30836262 Rat 2302380 Slep6 Serum leptin concentration QTL 6 3.36 blood leptin amount (VT:0005667) serum leptin level (CMO:0000780) 16 1 32139025 Rat 2307172 Activ4 Activity QTL 4 3.71 0.00023 locomotor behavior trait (VT:0001392) number of entries into a discrete space in an experimental apparatus (CMO:0000960) 16 1 33418960 Rat 1354584 Despr6 Despair related QTL 6 3.1 0.0067 locomotor behavior trait (VT:0001392) amount of time spent in voluntary immobility (CMO:0001043) 16 1 39533930 Rat 2303566 Bw90 Body weight QTL 90 2 body mass (VT:0001259) body weight (CMO:0000012) 16 1 39533930 Rat 631561 Hcuc2 Hepatic copper content QTL 2 2.8 hepatic copper amount (VT:0003065) liver total copper weight (CMO:0001507) 16 1 39533949 Rat 6903319 Bw114 Body weight QTL 114 2.7 0.0037 body mass (VT:0001259) body weight (CMO:0000012) 16 1 43534949 Rat 7411664 Foco30 Food consumption QTL 30 11 0.001 eating behavior trait (VT:0001431) feed conversion ratio (CMO:0001312) 16 1 44588133 Rat 1354625 Despr7 Despair related QTL 7 3.16 0.016 locomotor behavior trait (VT:0001392) amount of time spent in voluntary immobility (CMO:0001043) 16 1 44977551 Rat 1600378 Arunc4 Aerobic running capacity QTL 4 0.03 exercise endurance trait (VT:0002332) maximum distance run on treadmill (CMO:0001406) 16 380245 80345693 Rat 2293343 Glom16 Glomerulus QTL 16 7.4 kidney glomerulus integrity trait (VT:0010546) kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269) 16 832236 46053497 Rat 2312660 Bw95 Body weight QTL 95 0.05 inguinal fat pad mass (VT:0010424) inguinal fat pad weight to body weight ratio (CMO:0001253) 16 832236 59492508 Rat 2312663 Slep9 Serum leptin concentration QTL 9 0.001 blood leptin amount (VT:0005667) serum leptin level (CMO:0000780) 16 832236 59492508 Rat 2312666 Insul16 Insulin level QTL 16 0.01 blood insulin amount (VT:0001560) serum insulin level (CMO:0000358) 16 832236 59492508 Rat 2312669 Stl23 Serum triglyceride level QTL 23 0.01 blood triglyceride amount (VT:0002644) serum triglyceride level (CMO:0000360) 16 832236 59492508 Rat 1300133 Rf24 Renal function QTL 24 3.64 blood creatinine amount (VT:0005328) creatinine clearance (CMO:0000765) 16 3380150 21361552 Rat 2306902 Bp339 Blood pressure QTL 339 0.01 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 16 3380150 43025077 Rat 70183 BpQTLcluster13 Blood pressure QTL cluster 13 3.654 arterial blood pressure trait (VT:2000000) diastolic blood pressure (CMO:0000005) 16 4227609 43025077 Rat 70183 BpQTLcluster13 Blood pressure QTL cluster 13 3.654 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 16 4227609 43025077 Rat 70183 BpQTLcluster13 Blood pressure QTL cluster 13 3.654 arterial blood pressure trait (VT:2000000) mean arterial blood pressure (CMO:0000009) 16 4227609 43025077 Rat 737819 Hcas4 Hepatocarcinoma susceptibility QTL 4 4.43 liver integrity trait (VT:0010547) volume of individual liver tumorous lesion (CMO:0001078) 16 4227609 46975965 Rat 61405 Niddm6 Non-insulin dependent diabetes mellitus QTL 6 3.66 0.001 blood glucose amount (VT:0000188) plasma glucose level (CMO:0000042) 16 4227609 48972724 Rat 61338 Bp23 Blood pressure QTL 23 4.3 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 16 4227609 49227609 Rat 737826 Alc11 Alcohol consumption QTL 11 3.2 consumption behavior trait (VT:0002069) ethanol drink intake rate (CMO:0001407) 16 4227609 60252231 Rat 631517 Scl9 Serum cholesterol level QTL 9 3.3 blood cholesterol amount (VT:0000180) serum total cholesterol level (CMO:0000363) 16 15726433 21034895 Rat 70205 Gcr3 Gastric cancer resistance QTL 3 2.3 stomach morphology trait (VT:0000470) stomach tumor depth of invasion (CMO:0001888) 16 17696791 82635055 Rat 70205 Gcr3 Gastric cancer resistance QTL 3 2.3 stomach morphology trait (VT:0000470) stomach tumor depth of invasion (CMO:0001888) 16 17696791 82635055 Rat 70205 Gcr3 Gastric cancer resistance QTL 3 2.3 stomach morphology trait (VT:0000470) stomach tumor diameter (CMO:0001889) 16 17696791 82635055 Rat 70205 Gcr3 Gastric cancer resistance QTL 3 2.3 stomach morphology trait (VT:0000470) stomach tumor diameter (CMO:0001889) 16 17696791 82635055 Rat 70215 Niddm29 Non-insulin dependent diabetes mellitus QTL 29 3.54 blood glucose amount (VT:0000188) blood glucose level area under curve (AUC) (CMO:0000350) 16 19004435 75226532 Rat