Sugp1 (SURP and G patch domain containing 1) - Rat Genome Database
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Gene: Sugp1 (SURP and G patch domain containing 1) Mus musculus
Analyze
Symbol: Sugp1
Name: SURP and G patch domain containing 1
RGD ID: 1321430
MGI Page MGI
Description: Predicted to have RNA binding activity. Predicted to be involved in RNA splicing and mRNA processing. Predicted to localize to nucleoplasm. Orthologous to human SUGP1 (SURP and G-patch domain containing 1); INTERACTS WITH 1,2-dimethylhydrazine; 17alpha-ethynylestradiol; 2,2',4,4'-Tetrabromodiphenyl ether.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 5730496N02Rik; Sf; Sf4; splicing factor 4; SURP and G-patch domain-containing protein 1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Related Pseudogenes: Gm5315  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39870,495,435 - 70,524,997 (+)NCBIGRCm39mm39
GRCm38870,042,769 - 70,072,347 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl870,042,813 - 70,072,347 (+)EnsemblGRCm38mm10GRCm38
MGSCv37872,566,712 - 72,595,852 (+)NCBIGRCm37mm9NCBIm37
MGSCv36872,971,802 - 73,000,942 (+)NCBImm8
Celera872,603,099 - 72,632,001 (+)NCBICelera
Cytogenetic Map8B3.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:12477932   PMID:12520002   PMID:12594045   PMID:14610273   PMID:15489334   PMID:15782199   PMID:16141072  
PMID:16141073   PMID:16602821   PMID:21267068   PMID:21677750   PMID:22922362   PMID:27206982   PMID:30196744   PMID:30457570   PMID:32325033  


Genomics

Comparative Map Data
Sugp1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39870,495,435 - 70,524,997 (+)NCBIGRCm39mm39
GRCm38870,042,769 - 70,072,347 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl870,042,813 - 70,072,347 (+)EnsemblGRCm38mm10GRCm38
MGSCv37872,566,712 - 72,595,852 (+)NCBIGRCm37mm9NCBIm37
MGSCv36872,971,802 - 73,000,942 (+)NCBImm8
Celera872,603,099 - 72,632,001 (+)NCBICelera
Cytogenetic Map8B3.3NCBI
SUGP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1919,276,018 - 19,320,509 (-)EnsemblGRCh38hg38GRCh38
GRCh381919,276,033 - 19,320,509 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371919,387,320 - 19,431,321 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361919,248,322 - 19,292,307 (-)NCBINCBI36hg18NCBI36
Celera1919,291,389 - 19,335,381 (-)NCBI
Cytogenetic Map19p13.11NCBI
HuRef1918,951,058 - 18,994,630 (-)NCBIHuRef
CHM1_11919,388,088 - 19,432,088 (-)NCBICHM1_1
Sugp1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01621,100,923 - 21,131,795 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1621,100,924 - 21,131,795 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01620,950,430 - 20,985,149 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.01621,016,310 - 21,047,301 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41619,835,921 - 19,866,795 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11619,835,919 - 19,866,793 (-)NCBI
Celera1619,541,347 - 19,572,611 (-)NCBICelera
Cytogenetic Map16p14NCBI
Sugp1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555242,563,263 - 2,584,834 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555242,563,299 - 2,584,046 (+)NCBIChiLan1.0ChiLan1.0
SUGP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11919,718,310 - 19,762,402 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1919,718,310 - 19,762,402 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01918,715,215 - 18,758,712 (-)NCBIMhudiblu_PPA_v0panPan3
SUGP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl2043,891,750 - 43,922,986 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.12043,891,572 - 43,922,991 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Sugp1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049365962,133,090 - 2,164,042 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SUGP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl258,574,540 - 58,615,449 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1258,574,434 - 58,615,054 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
SUGP1
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1617,743,065 - 17,784,325 (-)NCBI
ChlSab1.1 Ensembl617,743,388 - 17,784,126 (-)Ensembl
Sugp1
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046249082,145,644 - 2,165,066 (-)NCBI

Position Markers
BE136470  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38870,072,137 - 70,072,257UniSTSGRCm38
MGSCv37872,596,036 - 72,596,156UniSTSGRCm37
Celera872,632,185 - 72,632,305UniSTS
Cytogenetic Map8C1UniSTS
Cytogenetic Map8B3.3UniSTS
Whitehead/MRC_RH8741.8UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1558870Eae36_mexperimental allergic encephalomyelitis susceptibility 36 (mouse)Not determined81472316071045600Mouse
1357811Orq3_movulation rate QTL 3 (mouse)Not determined83201654471287993Mouse
4141437W10q14_mweight 10 weeks QTL 14 (mouse)Not determined3201654471287993Mouse
4141172W6q9_mweight 6 weeks QTL 9 (mouse)Not determined3201654471287993Mouse
4140966Egq12_mearly growth QTL 12 (mouse)Not determined3201654471287993Mouse
4140967Bmd39_mbone mineral density 39 (mouse)Not determined832016544117238700Mouse
1558875Eae31_mexperimental allergic encephalomyelitis susceptibility 31 (mouse)Not determined834642776114837007Mouse
1301013Capsq4_mcapsaicin sensitivity related QTL 4 (mouse)Not determined83616300092728652Mouse
27226754Femd6_mfemur midshaft diameter 6, 10 week (mouse)837400000109600000Mouse
12904744Carcdq1_mcardiac collagen deposition QTL 1 (mouse)83970925694689598Mouse
1301544Iba3_minduction of brown adipocytes 3 (mouse)Not determined84429488078295025Mouse
1301717Adip4_madiposity 4 (mouse)Not determined84763703081637146Mouse
10766453Char11_mP. chabaudi malaria resistance QTL 11 (mouse)84763703081637146Mouse
1301441Skull11_mskull morphology 11 (mouse)Not determined84773713481737254Mouse
1357715Alaa3_malopecia areata 3 (mouse)Not determined84879293982793021Mouse
14746987Manh64_mmandible shape 64 (mouse)85005330684053306Mouse
14747005Mancz7_mmandible centroid size 7 (mouse)85005330684053306Mouse
14700686Civq3_mcerebral infarct volume QTL 3 (mouse)85188219185882191Mouse
1301506Aevm1_mautoimmune extremity vasculitis in MRL mice 1 (mouse)Not determined85428781788287993Mouse
1301952Im3_mimmunoregulatory 3 (mouse)Not determined85470661488706763Mouse
10412287Carg3_mCandida albicans resistance gene 3 (mouse)Not determined85554502889545028Mouse
11353828Gf7_mgonadal fat pad weight 7 (mouse)85820147992201479Mouse
10043975Obq31_mobesity QTL 31 (mouse)Not determined85840977692409776Mouse
1301688Orch6_mautoimmune orchitis resistance 6 (mouse)Not determined86078685094786976Mouse
4141285Tgq18_mtriglyceride QTL 18 (mouse)Not determined6346010797460107Mouse
4141797Skmw16_mskeletal muscle weight 16 (mouse)Not determined86393954797939696Mouse
1357787Vtbt5_mvertebral trabecular bone trait 5 (mouse)Not determined86535776899357920Mouse
10043992Hbnr11_mHeligmosomoides bakeri nematode resistance 11 (mouse)Not determined86560020799600347Mouse
10766466Char12_mP. chabaudi malaria resistance QTL 12 (mouse)86826982782600347Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:85
Count of miRNA genes:81
Interacting mature miRNAs:85
Transcripts:ENSMUST00000011450
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001368391 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_027481 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030243755 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036154283 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC167132 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF521129 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK017736 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK090191 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK156508 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK164195 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK187764 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK195199 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK212579 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC027188 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC120919 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC120920 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466569 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000011450   ⟹   ENSMUSP00000011450
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl870,042,813 - 70,072,347 (+)Ensembl
RefSeq Acc Id: ENSMUST00000211808
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl870,043,034 - 70,066,911 (+)Ensembl
RefSeq Acc Id: ENSMUST00000213035
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl870,043,049 - 70,058,319 (+)Ensembl
RefSeq Acc Id: NM_001368391   ⟹   NP_001355320
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39870,495,437 - 70,524,997 (+)NCBI
GRCm38870,042,787 - 70,072,347 (+)NCBI
Sequence:
RefSeq Acc Id: NM_027481   ⟹   NP_081757
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39870,495,437 - 70,524,997 (+)NCBI
GRCm38870,042,787 - 70,072,347 (+)NCBI
MGSCv37872,566,712 - 72,595,852 (+)RGD
Celera872,603,099 - 72,632,001 (+)RGD
cM Map8 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_030243755   ⟹   XP_030099615
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39870,495,435 - 70,524,614 (+)NCBI
GRCm38870,042,770 - 70,071,964 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036154283   ⟹   XP_036010176
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39870,509,036 - 70,524,614 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_081757   ⟸   NM_027481
- UniProtKB: Q8CH02 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_030099615   ⟸   XM_030243755
- Peptide Label: isoform X1
RefSeq Acc Id: NP_001355320   ⟸   NM_001368391
RefSeq Acc Id: ENSMUSP00000011450   ⟸   ENSMUST00000011450
RefSeq Acc Id: XP_036010176   ⟸   XM_036154283
- Peptide Label: isoform X2
Protein Domains
G-patch

Promoters
RGD ID:8667265
Promoter ID:EPDNEW_M11664
Type:multiple initiation site
Name:Sugp1_1
Description:Mus musculus SURP and G patch domain containing 1 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M11665  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38870,042,787 - 70,042,847EPDNEW
RGD ID:8667267
Promoter ID:EPDNEW_M11665
Type:multiple initiation site
Name:Sugp1_2
Description:Mus musculus SURP and G patch domain containing 1 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M11664  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38870,043,034 - 70,043,094EPDNEW
RGD ID:6843717
Promoter ID:MM_KWN:54655
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000011450,   NM_001167939,   NM_028993,   UC009LYL.1,   UC009LYM.1,   UC009LYN.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36872,565,951 - 72,567,017 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1917866 AgrOrtholog
Ensembl Genes ENSMUSG00000011306 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSMUSP00000011450 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000011450 ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.10.790 UniProtKB/Swiss-Prot
InterPro G_patch_dom UniProtKB/Swiss-Prot
  SUGP1/2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Surp UniProtKB/Swiss-Prot
  SWAP/Surp_sf UniProtKB/Swiss-Prot
KEGG Report mmu:70616 UniProtKB/Swiss-Prot
MGD MGI:1917866 ENTREZGENE
NCBI Gene 70616 ENTREZGENE
PANTHER PTHR23340 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam G-patch UniProtKB/Swiss-Prot
  Surp UniProtKB/Swiss-Prot
PhenoGen Sugp1 PhenoGen
PROSITE G_PATCH UniProtKB/Swiss-Prot
  SURP UniProtKB/Swiss-Prot
SMART G_patch UniProtKB/Swiss-Prot
  SWAP UniProtKB/Swiss-Prot
Superfamily-SCOP SSF109905 UniProtKB/Swiss-Prot
UniGene Mm.17665 ENTREZGENE
UniProt Q3TPQ8_MOUSE UniProtKB/TrEMBL
  Q8CH02 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary Q0VAT9 UniProtKB/Swiss-Prot
  Q3U0W3 UniProtKB/Swiss-Prot
  Q8R094 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-07-27 Sugp1  SURP and G patch domain containing 1  Sf4  splicing factor 4  Symbol and/or name change 5135510 APPROVED