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Gene: Lrrc7 (leucine rich repeat containing 7) Rattus norvegicus
Symbol: Lrrc7
Name: leucine rich repeat containing 7
RGD ID: 708527
Description: Exhibits protein C-terminus binding activity. Involved in positive regulation of neuron projection development and response to organic cyclic compound. Localizes to several cellular components, including axon initial segment; dendritic spine; and postsynaptic density. Colocalizes with actin cytoskeleton. Orthologous to human LRRC7 (leucine rich repeat containing 7); PARTICIPATES IN calcium/calmodulin dependent kinase 2 signaling pathway; INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.
Type: protein-coding
Also known as: densin; densin 13T-16; densin 13T-17; densin 13T-23; densin 13T-29; densin 13T-41; densin 13T-43; densin 13T-57; densin 13T-57C; densin 13T-72; densin 13T-89; densin-180; leucine-rich repeat-containing protein 7; LOC117284
Homo sapiens (human) : LRRC7 (leucine rich repeat containing 7)  HGNC  Alliance
Mus musculus (house mouse) : Lrrc7 (leucine rich repeat containing 7)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Lrrc7 (leucine rich repeat containing 7)
Pan paniscus (bonobo/pygmy chimpanzee) : LRRC7 (leucine rich repeat containing 7)
Canis lupus familiaris (dog) : LRRC7 (leucine rich repeat containing 7)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lrrc7 (leucine rich repeat containing 7)
Sus scrofa (pig) : LRRC7 (leucine rich repeat containing 7)
Chlorocebus sabaeus (African green monkey) : LRRC7 (leucine rich repeat containing 7)
Heterocephalus glaber (naked mole-rat) : Lrrc7 (leucine rich repeat containing 7)
more info ...
Allele / Splice: Lrrc7Tn(sb-T2/Bart3)2.253Mcwi  
Genetic Models: F344-Lrrc7Tn(sb-T2/Bart3)2.253Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.02264,910,594 - 265,300,860 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2264,910,594 - 265,300,868 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02283,549,882 - 283,934,360 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42256,228,792 - 256,644,029 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12256,243,398 - 256,458,663 (-)NCBI
Celera2238,947,973 - 239,318,491 (-)NCBICelera
Cytogenetic Map2q45NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Lrrc7
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 708527
Created: 2003-09-23
Species: Rattus norvegicus
Last Modified: 2020-09-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.