Gene: Plcb3 (phospholipase C beta 3) Rattus norvegicus
Symbol: Plcb3
Name: phospholipase C beta 3
Description: ENCODES a protein that exhibits phosphatidylinositol phospholipase C activity; cadherin binding (ortholog); calmodulin binding (ortholog); INVOLVED IN G-protein coupled receptor signaling pathway; inositol trisphosphate metabolic process; phosphatidylinositol catabolic process; PARTICIPATES IN endothelin signaling pathway; G protein mediated signaling pathway via Galphaq family; protein kinase C (PKC) signaling pathway; ASSOCIATED WITH diabetes mellitus, experimental; Myocardial Infarction; Huntington Disease (ortholog); FOUND IN cytosol; sarcolemma; nucleoplasm (ortholog); INTERACTS WITH (R)-noradrenaline; 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine
Type: protein-coding
Also known as: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3; 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-3; phosphoinositide phospholipase C-beta-3; phospholipase C, beta 3 (phosphatidylinositol-specific); phospholipase C-beta-3; PLC-beta-3
Homo sapiens (human) : PLCB3 (phospholipase C beta 3)  HGNC  Alliance
Mus musculus (house mouse) : Plcb3 (phospholipase C, beta 3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Plcb3 (phospholipase C beta 3)
Pan paniscus (bonobo/pygmy chimpanzee) : PLCB3 (phospholipase C beta 3)
Canis lupus familiaris (dog) : PLCB3 (phospholipase C beta 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Plcb3 (phospholipase C beta 3)
more info ...
Allele / Splice: Plcb3Tn(sb-T2/Bart3)2.69Mcwi  
Genetic Models: F344-Plcb3Tn(sb-T2/Bart3)2.69Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01222,207,887 - 222,224,993 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01229,198,739 - 229,215,831 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41209,628,425 - 209,643,694 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11209,786,729 - 209,802,063 (-)NCBI
Celera1201,678,898 - 201,694,162 (-)NCBICelera
Cytogenetic Map1q43NCBI
RH 3.4 Map11521.0RGD
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Plcb3
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 61993
Created: 2001-04-11
Species: Rattus norvegicus
Last Modified: 2018-03-20
Status: ACTIVE