Bp143 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL Registration

QTL: Bp143 (Blood pressure QTL 143) Rattus norvegicus

Symbol: Bp143
Name: Blood pressure QTL 143
RGD ID: 634312
Trait: arterial blood pressure trait   (VT:2000000)    
Measurement Type: systolic blood pressure   (CMO:0000004)    
LOD Score: 3.0
P Value: 2.0E-4
Variance: 12.0
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81203,300,512 - 229,359,342RGD_MAPPER_PIPELINE
mRatBN7.21182,623,426 - 219,932,796RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01198,446,729 - 240,017,341RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01218,337,839 - 247,303,260RGDRnor5.0
RGSC_v3.41198,853,034 - 225,625,256RGDRGSC3.4
RGSC_v3.11199,003,017 - 225,789,279RGD
Cross Type: intercross
Strains Crossed: SS/Hsd SR/Hsd 
JBrowse: View Region in Genome Browser (JBrowse)
Model




  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bp143Rathypertension  IDA 631325 RGD 

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bp143Ratincreased systemic arterial blood pressure  QTM 631325 RGD 

Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bp143Ratsystolic blood pressure  IDA 631325 RGD 

Experimental Condition
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bp143Ratcontrolled sodium content diet  IDA 631325 RGD 

Measurement Method
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bp143Ratradiotelemetry  IDA 631325 RGD 

Rat Strain
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bp143RatSR/Hsd  IEA 631325 RGD 
Bp143RatSS/Hsd  IEA 631325 RGD 

Vertebrate Trait
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bp143Ratarterial blood pressure trait  IDA 631325 RGD 


#
Reference Title
Reference Citation
1. The dual AngII/AVP receptor gene N119S/C163R variant exhibits sodium-induced dysfunction and cosegregates with salt-sensitive hypertension in the Dahl salt-sensitive hypertensive rat model. Ruiz-Opazo N, etal., Mol Med 2002 Jan;8(1):24-32.


1 to 20 of 874 rows
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
41367722LOC120099939uncharacterized LOC1200999391182637160182642709Rat
7624587LOC102556135uncharacterized LOC1025561351182651431182657380Rat
41357835Rnu1-140RNA, U1 small nuclear 1401182658147182658307Rat
2926Itgamintegrin subunit alpha M1182659047182709501Rat
1561123Itgaxintegrin subunit alpha X1182709653182740709Rat
71075Itgadintegrin subunit alpha D1182759762182788422Rat
2385Cox6a2cytochrome c oxidase subunit 6A21182788528182790746Rat
9074604Zfp696zinc finger protein 6961182809465182820548Rat
1306553Armc5armadillo repeat containing 51182820141182826913Rat
620173Tgfb1i1transforming growth factor beta 1 induced transcript 11182828553182835465Rat
620217Slc5a2solute carrier family 5 member 21182847185182853309Rat
1310127Rusf1RUS family member 11182852257182881652Rat
1306725Ahspalpha hemoglobin stabilizing protein1182879901182885508Rat
40967984LOC120099940uncharacterized LOC1200999401182890478182896780Rat
9242866LOC103691239uncharacterized LOC1036912391182934054182937398Rat
3562Rgs10regulator of G-protein signaling 101182946334182987729Rat
1595845Tial1Tia1 cytotoxic granule-associated RNA binding protein-like 11183008358183045092Rat
1596229Rps2-ps13ribosomal protein S2, pseudogene 131183041102183041973Rat
11482889LOC10834978340S ribosomal protein S19 pseudogene1183046566183051192Rat
1307794Bag3BAG cochaperone 31183103038183126862Rat

1 to 20 of 874 rows
1 to 20 of 1128 rows
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Expected Size
Chr
Start
Stop
Species
Match
5083721AI0102312151182656409182657281Ratregion
10818D1Smu101271182657959182658086Ratregion
43350D1Got1662211182657961182658182Ratregion
625784D1Got1631251182743688182743813Ratregion
5048438RH1329042151182788162182788377Ratregion
5025748RH1295092801182788619182788899Ratregion
5503078Cox6a22121182788679182788891Ratregion
5051819RH946762791182790344182790624Ratregion
5040730RH1284501891182826646182826835Ratregion
5085082AI5480561511182852272182852423Ratregion
5043456RH1300361811182885299182885480Ratregion
5500755D22S11755841182904517182905880Ratregion
5075496RH1386271531182945573182945726Ratregion
5030797BE1201651921182945823182946015Ratregion
5047570RH1324042121182946504182946716Ratregion
5086407AI4123331541183009291183009445Ratregion
5056487RH1444072851183011202183011487Ratregion
5061112AW5323911901183102664183102854Ratregion
5500182D7Mit1054901183150556183151046Ratregion
5053637RH1427641851183268631183268816Ratregion
1 to 20 of 1128 rows

Flank 1: (D1Rat129)
Rat AssemblyChrPosition (strand)Source
GRCr81203,300,512 - 203,300,759 (+)Marker Load Pipeline
Rnor_5.01218,337,839 - 218,338,087NCBI
RGSC_v3.41198,853,034 - 198,853,281RGD
RGSC_v3.11199,003,017 - 199,003,326RGD
RH 3.4 Map11437.9RGD
RH 3.4 Map11437.9UniSTS
SHRSP x BN Map1101.4699UniSTS
SHRSP x BN Map1101.4699RGD
Peak: (D1Rat188)
Rat AssemblyChrPosition (strand)Source
GRCr81210,707,476 - 210,707,719 (+)Marker Load Pipeline
mRatBN7.21201,277,990 - 201,278,233 (+)MAPPER
Rnor_6.01219,231,914 - 219,232,156NCBI
Rnor_5.01226,102,565 - 226,102,807UniSTS
RGSC_v3.41206,567,563 - 206,567,907RGD
RGSC_v3.41206,567,644 - 206,567,886UniSTS
RGSC_v3.11206,721,097 - 206,721,339RGD
Celera1198,823,049 - 198,823,291UniSTS
RH 3.4 Map11558.9RGD
RH 3.4 Map11558.9UniSTS
RH 2.0 Map11126.4RGD
SHRSP x BN Map1106.0299RGD
FHH x ACI Map196.59RGD
Cytogenetic Map1q42UniSTS
Flank 2: (D1Rat298)
Rat AssemblyChrPosition (strand)Source
GRCr81229,359,117 - 229,359,342 (+)Marker Load Pipeline
mRatBN7.21219,932,573 - 219,932,796 (+)MAPPER
Rnor_6.01240,017,117 - 240,017,341NCBI
Rnor_5.01247,303,036 - 247,303,260UniSTS
RGSC_v3.41225,625,031 - 225,625,256RGD
RGSC_v3.41225,625,032 - 225,625,256UniSTS
RGSC_v3.11225,789,054 - 225,789,279RGD
Celera1217,158,892 - 217,159,116UniSTS
SHRSP x BN Map1116.5799UniSTS
SHRSP x BN Map1116.5799RGD
Cytogenetic Map1q51UniSTS


1 to 10 of 142 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
8693637Alc29Alcohol consumption QTL 292.70.258drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)1207987464234238494Rat
1578778Pur4Proteinuria QTL 43.30.003urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)1150700247252085048Rat
1357335Bw39Body weight QTL 393.3body mass (VT:0001259)body weight (CMO:0000012)1197814409242814409Rat
1578780Cm52Cardiac mass QTL 523.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)181591954219808434Rat
61455Niddm7Non-insulin dependent diabetes mellitus QTL 75.5blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)1214537555238757011Rat
1302787Stl25Serum triglyceride level QTL 252.70.0073blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)1180359209210702199Rat
70160Bw18Body weight QTL 185.7body mass (VT:0001259)body weight (CMO:0000012)1144267353196383668Rat
1549830Bss1Bone structure and strength QTL 14.8femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)1172609619217609619Rat
7794788Mcs32Mammary carcinoma susceptibility QTL 322.61mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)1115540693238914717Rat
70163Bw20Body weight QTL 205.1body mass (VT:0001259)body weight (CMO:0000012)1174133260219133260Rat

1 to 10 of 142 rows


Database
Acc Id
Source(s)
NCBI Gene Bp143

Note Type Note Reference
qtl_cross_type intercross  
qtl_general associates with increased blood pressure 631325