Gluco56 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL: Gluco56 (Glucose level QTL 56) Rattus norvegicus

Symbol: Gluco56
Name: Glucose level QTL 56
RGD ID: 2314011
Trait: blood glucose amount   (VT:0000188)    
Measurement Type: blood glucose level area under curve (AUC)   (CMO:0000350)    
LOD Score: Not Available
P Value: Not Available
Variance: Not Available
Inheritance Type: additive
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21199,773,958 - 202,166,723RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01217,776,868 - 220,128,172RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01224,635,116 - 227,059,170RGDRnor5.0
RGSC_v3.41205,040,948 - 207,483,209RGDRGSC3.4
Cross Type: Not Available
Strains Crossed: NMcwi:HS 
JBrowse: View Region in Genome Browser (JBrowse)
Model



Candidate Gene Status
Tpcn2 is a candidate Gene for Gluco56

Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

Experimental Condition

Measurement Method

Vertebrate Trait

Rat Strain
NMcwi:HS  (IEA)

References

References - curated
# Reference Title Reference Citation
1. Fine-mapping a locus for glucose tolerance using heterogeneous stock rats. Solberg Woods L, etal., Physiol Genomics. 2010 Jan 12.
2. Identification of a novel gene for diabetic traits in rats, mice, and humans. Tsaih SW, etal., Genetics. 2014 Sep;198(1):17-29. doi: 10.1534/genetics.114.162982.

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
2758Gstp1glutathione S-transferase pi 11201337762201340230Rat
61954Galgalanin and GMAP prepropeptide1200650439200655302Rat
3262Pcpyruvate carboxylase1201799374201898412Rat
3751Sptbn2spectrin, beta, non-erythrocytic 21202002970202045343Rat
3375Ppp1caprotein phosphatase 1 catalytic subunit alpha1201485117201488734Rat
2396Cpt1acarnitine palmitoyltransferase 1A1200564634200627059Rat
628800Smim38small integral membrane protein 381200366561200371976Rat
620542Rbm14RNA binding motif protein 141202076940202105688Rat
68325Ighmbp2immunoglobulin mu DNA binding protein 21200506641200529293Rat
708478MrgprfMAS related GPR family member F1200464100200473588Rat
68384Ccnd1cyclin D11200089002200098524Rat
61944Chkacholine kinase alpha1201076804201125517Rat
2382Coro1bcoronin 1B1201442977201448416Rat
1306710Pitpnm1phosphatidylinositol transfer protein, membrane-associated 11201394099201407523Rat
1303171Clcf1cardiotrophin-like cytokine factor 11201507763201517607Rat
620126Fgf3fibroblast growth factor 31200001162200005539Rat
621792Actn3actinin alpha 31202159081202175012Rat
735136Tcirg1T-cell immune regulator 1, ATPase H+ transporting V0 subunit A31201127034201138787Rat
2062Grk2G protein-coupled receptor kinase 21201580823201601580Rat
620403Ccscopper chaperone for superoxide dismutase1202113792202134931Rat
2193Bc1brain cytoplasmic RNA 11200073610200073763Rat
621876Syt12synaptotagmin 121201729307201760192Rat
1304637Lto1LTO1 maturation factor of ABCE11200074247200080951Rat
1306083Cabp4calcium binding protein 41201428671201442950Rat
1305824Tmem134transmembrane protein 1341201419225201424778Rat
1306343Fam18b-ps1family with sequence similarity 18, member B, pseudogene 11200971080200972723Rat
1305144Rps6kb2ribosomal protein S6 kinase B21201451265201458096Rat
1307603Gstp3glutathione S-transferase pi 31201355682201358216Rat
738040MrgprdMAS related GPR family member D1200479204200487902Rat
1308519Pold4DNA polymerase delta 4, accessory subunit1201526591201528406Rat
620127Fgf4fibroblast growth factor 41200023937200027793Rat
1305394Acy3aminoacylase 31201279751201285803Rat
620166Fgf19fibroblast growth factor 191200056526200060980Rat
1308679Ssh3slingshot protein phosphatase 31201557167201565577Rat
1310203Mrpl21mitochondrial ribosomal protein L211200529416200542568Rat
1311984Unc93b1unc-93 homolog B1, TLR signaling regulator1201167388201178343Rat
1310985Rhodras homolog family member D1201708699201724405Rat
1309156Ankrd13dankyrin repeat domain 13D1201565712201577987Rat
1309788Tesmintestis expressed metallothionein like protein1200629688200648434Rat
1306891Rbm4RNA binding motif protein 41202078442202087506Rat
1308234Carns1carnosine synthase 11201459061201470019Rat
1311779Tpcn2two pore segment channel 21200416538200446252Rat
1310786Ano1anoctamin 11199751439199900099Rat
1311490Tbc1d10cTBC1 domain family, member 10C1201476258201484876Rat
1311637Kmt5blysine methyltransferase 5B1201000444201049819Rat
1309419Kdm2alysine demethylase 2A1201612427201682359Rat
1309436Ndufs8NADH:ubiquinone oxidoreductase core subunit S81201140585201144573Rat
1309261Rce1Ras converting CAAX endopeptidase 11201899358201902593Rat
1308181Ctsfcathepsin F1202152777202158525Rat
1307145Ppp6r3protein phosphatase 6, regulatory subunit 31200693128200807578Rat
1309329Lrp5LDL receptor related protein 51200814247200917581Rat
1309040Nudt8nudix hydrolase 81201293660201295233Rat
1307473Doc2gdouble C2-like domains, gamma1201295377201299867Rat
628619Aiparyl-hydrocarbon receptor-interacting protein1201408002201419220Rat
1359343Rbm4bRNA binding motif protein 4B1202047934202058025Rat
1559601Ptprcapprotein tyrosine phosphatase, receptor type, C-associated protein1201449133201451293Rat
1311946C1h11orf24similar to human chromosome 11 open reading frame 241200945188200953953Rat
1359546Aldh3b1aldehyde dehydrogenase 3 family, member B11201145309201162675Rat
1359247Ndufv1NADH:ubiquinone oxidoreductase core subunit V11201300365201305461Rat
1585230Aldh3b3aldehyde dehydrogenase 3 family, member B31201193832201201666Rat
1584082Gpr152G protein-coupled receptor 1521201435878201438373Rat
1584144Tbx10T-box transcription factor 101201285729201292676Rat
1584166Aldh3b2aldehyde dehydrogenase 3 family, member B21201250260201264699Rat
1563323Top6blTOP6B like initiator of meiotic double strand breaks1201902564201989945Rat
1563670Cabp2calcium binding protein 21201374649201380469Rat
1585286Lrfn4leucine rich repeat and fibronectin type III domain containing 41201888569201891861Rat
1588883Cdk2ap2cyclin-dependent kinase 2 associated protein 21201391056201393137Rat
1596153Ccdc87coiled-coil domain containing 871202135021202137717Rat
1597421C1h11orf86similar to human chromosome 11 open reading frame 861201784009201785916Rat
1597413Slc25a5-ps10solute carrier family 25 member 5, pseudogene 101201788617201799402Rat
2319938Rad9aRAD9 checkpoint clamp component A1201488511201553582Rat
7622947Utp3-ps1UTP3, small subunit processome component, pseudogene 11200799279200800009Rat
7689565LOC102553046uncharacterized LOC1025530461202003101202022459Rat
9106200LOC103691274uncharacterized LOC1036912741201553660201556013Rat
9323695Apoa2l1apolipoprotein A-II like 11200803787200804741Rat
11366915LOC10834972540S ribosomal protein S9 pseudogene1200908176200917389Rat
11455008LOC108349678uncharacterized LOC1083496781200007802200018418Rat
11470190Trnap-agg2transfer RNA proline (anticodon AGG) 21201060155201060231Rat
11418059LOC108349679uncharacterized LOC1083496791200210221200234295Rat
11401413Rpl35a-ps6ribosomal protein L35A, pseudogene 61201440397201440848Rat
11504246Trnan-guu1transfer RNA asparagine (anticodon GUU) 11200749189200749261Rat
41285163Aldh3b2l1aldehyde dehydrogenase 3 family, member B2 like 11201228414201250204Rat
41286380LOC120099968uncharacterized LOC1200999681200250061200268329Rat
41267992Aldh3b2-ps1aldehyde dehydrogenase 3 family, member B2, pseudogene 11201226907201244192Rat
41399942Rps10-ps18ribosomal protein S10, pseudogene 181200084281200084735Rat
41071816LOC120099969uncharacterized LOC1200999691200344504200353691Rat
41030580Aldh3b3l-ps1aldehyde dehydrogenase 3 family, member B3-like, pseudogene 11201200291201218456Rat
41222380Rnu6-993RNA, U6 small nuclear 9931200728408200728511Rat
41238308LOC120099967uncharacterized LOC1200999671200189261200203943Rat
41309215LOC120100386small nucleolar RNA SNORA321201660247201660328Rat

Markers in Region
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolExpected SizeChrStartStopSpeciesMatch
10699D1Wox361451201337534201337679Ratregion
37184D1Rat1882391201277990201278233Ratregion
36580D1Rat1121411201284552201284693Ratregion
35615D1Rat701521199773958199774075Ratregion
39982D1Rat3231411202166582202166723Ratregion
42279D1Rat4711381201348517201348657Ratregion
43384D1Got1892641200611501200611765Ratregion
43385D1Got2761161200927006200927122Ratregion
43387D1Got1881151200927008200927123Ratregion
43388D1Got1901731200408630200408806Ratregion
43389D1Got1871671201818238201818406Ratregion
1631189D1Wox722111200719109200719318Ratregion
1631819D1Wox591471200091550200091697Ratregion
1632933D1Cebr31211200396561200396680Ratregion
1635984D1Wox631901201075483201075673Ratregion
7206000Ccnd11831200096780200098354Ratregion
7192371Ppp1ca511201488292201488343Ratregion
7206460Slc25a59231201788774201789819Ratregion
5038716BB3482871231201729331201729454Ratregion
5038734AW7430722221201526786201527008Ratregion
5036927AU0496501361200478033200478169Ratregion
5037035AU0499951371200619912200620046Ratregion
5028601AF0649841141200814315200814429Ratregion
5028603AI481912941202158393202158487Ratregion
5031404PMC16025P13931202134418202134811Ratregion
5028747RH1421632161202095076202095292Ratregion
5034508BI2801172201200090348200090568Ratregion
5034532BE1191742031201164936201165139Ratregion
5035120BE0962902151202051192202051407Ratregion
5027050RH1345412011200089149200089350Ratregion
5035300AA9555382051202057717202057922Ratregion
5027537AI326383891201709271201709360Ratregion
5027699WI-152441051201580885201580992Ratregion
5030237BE0992731611202086401202087408Ratregion
5033059RH1374392121202045028202045240Ratregion
5033621RH1394952131200506428200506641Ratregion
5055863RH1440461561202046984202047140Ratregion
5051595AW5367901071201612636201612743Ratregion
5057185D1Bda452191201581925201582223Ratregion
5057400AA9263371521201565744201565896Ratregion
5054829RH1434491281201293552201293680Ratregion
5056213RH1442481721201999694201999866Ratregion
5052557AA9601921091200626820200626929Ratregion
5052799RH1422801841201447822201448112Ratregion
5059816BE0979602101202074608202074818Ratregion
5050124RH1338761801200091759200091939Ratregion
5052559N281271891200693211200693400Ratregion
5052633RH1421742141200471827200472041Ratregion
5054177RH1430741891201459343201459532Ratregion
5051729RH946241861201898189201898375Ratregion
5046620RH1318582101201148806201149016Ratregion
5049400RH1334592191202084870202085089Ratregion
5047100RH1321331811201899487201899667Ratregion
5047248RH1322181991201145390201145589Ratregion
5042072RH1292221871201612485201612672Ratregion
5048458RH1329151851201380262201380447Ratregion
5040340RH1282272071201448120201448327Ratregion
5042958RH1297462021202113823202114025Ratregion
5040678RH1284211831202088459202088642Ratregion
5043330RH1299641841201126014201126198Ratregion
5041008RH1286101801201040087201040267Ratregion
5043908RH1302981941201528120201528314Ratregion
5040366RH1282421841200626749200626933Ratregion
7193045Fgf411471200024301200025448Ratregion
5041434RH1288541511201451383201451534Ratregion
5072756RH1370352151201337830201338201Ratregion
5072772RH1370442141200650520200651979Ratregion
5075016RH1383502311202077005202077236Ratregion
5071988RH1354002071201901332201901539Ratregion
5075456RH1386041251201428787201428912Ratregion
5072616RH1369521811201451081201451262Ratregion
5079696RH1411501841202055908202056092Ratregion
5079888RH1412612151201709066201709281Ratregion
5072148RH1366801851200693198200693383Ratregion
5072470RH1368682191200080683200080902Ratregion
5070083RH944631761201581490201581666Ratregion
5070516D19Ertd98e2631201899364201899627Ratregion
5065354AA9572511911202078281202078472Ratregion
5062406BE1066482071200195313200195520Ratregion
5065886AA9643061281200473409200473537Ratregion
5061332BE0996771711201488954201489125Ratregion
5063054BE11365501201299447201299803Ratregion
5063138BI3013141661201845141201845307Ratregion
5064668BF3995421851201565035201565220Ratregion
5087273AW5322351781201476297201476475Ratregion
5087502PMC21059P16281200625770200626398Ratregion
5087342AI2289522021202043295202043497Ratregion
5083181BF3909461531200972034200972187Ratregion
5081731AI5110891911201406349201407308Ratregion
5084806AI2358541501201689905201690055Ratregion
5088473AU0485901251200489819200489944Ratregion
5080718RH1417412011201282826201283027Ratregion
5082859BF3902961501200510026200510176Ratregion
5082969BF3905161821201637567201637749Ratregion
5085038AA892051931201125184201125277Ratregion
5083157BF3908961781201549434201549612Ratregion
5086590BE1064761931201578924201579116Ratregion
5085230BM3899261571202085471202085628Ratregion
5503037Actn31611202166442202167470Ratregion
5507606Ccnd11671200091848200093446Ratregion
5503052Lrp5981200823966200824064Ratregion
5503652UniSTS:4654725081200090353200090861Ratregion
5503857Ppp1ca3141201485193201486097Ratregion
5503603UniSTS:4647855731200024838200025411Ratregion
5504642PMC321442P22061200096019200096764Ratregion
5504899ha31409571202058266202059223Ratregion
5504774PMC98458P12001200098199200098399Ratregion
5505366Adrbk111851201581049201582234Ratregion
5507207UniSTS:2252741631201125304201125466Ratregion
5507093UniSTS:2245101701201614169201614339Ratregion
550015702.MMHAP94FRA8.seq6631200389913200390576Ratregion
5501600RH705061441202057790202057934Ratregion
5502068MARC_26579-26580:1033749235:12871201302681201304014Ratregion
5502226Fgf411781200024265200025443Ratregion
5507171UniSTS:2249541481202010865202011013Ratregion
5502407RH1247471211201408194201408315Ratregion
5502545RH1252331191201125301201125420Ratregion
Position Markers

Flank 1: (D1Rat70)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21199,773,958 - 199,774,075 (+)MAPPER
Rnor_6.01217,776,868 - 217,776,984NCBI
Rnor_5.01224,635,116 - 224,635,232UniSTS
RGSC_v3.41205,040,948 - 205,041,279RGD
RGSC_v3.41205,041,048 - 205,041,164UniSTS
RGSC_v3.11205,194,401 - 205,194,732RGD
Celera1197,333,311 - 197,333,427UniSTS
RH 3.4 Map11560.2UniSTS
RH 3.4 Map11560.2RGD
RH 2.0 Map11111.4RGD
SHRSP x BN Map1106.09RGD
FHH x ACI Map196.59RGD
Cytogenetic Map1q42UniSTS
Peak: (D1Rat112)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21201,284,552 - 201,284,693 (+)MAPPER
Rnor_6.01219,238,476 - 219,238,616NCBI
Rnor_5.01226,109,127 - 226,109,267UniSTS
RGSC_v3.41206,574,205 - 206,574,346RGD
RGSC_v3.41206,574,206 - 206,574,346UniSTS
RGSC_v3.11206,727,659 - 206,727,799RGD
Celera1198,829,611 - 198,829,751UniSTS
RH 3.4 Map11559.5UniSTS
RH 3.4 Map11559.5RGD
RH 2.0 Map11122.4RGD
FHH x ACI Map196.59RGD
Cytogenetic Map1q42UniSTS
Flank 2: (D1Rat323)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21202,166,582 - 202,166,723 (+)MAPPER
Rnor_6.01220,128,032 - 220,128,172NCBI
Rnor_5.01227,059,030 - 227,059,170UniSTS
RGSC_v3.41207,483,068 - 207,483,209RGD
RGSC_v3.41207,483,069 - 207,483,209UniSTS
RGSC_v3.11207,636,512 - 207,636,708RGD
Celera1199,706,203 - 199,706,343UniSTS
FHH x ACI Map197.69RGD
FHH x ACI Map197.69UniSTS
Cytogenetic Map1q43UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1578778Pur4Proteinuria QTL 43.30.003urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)1150700247252085048Rat
1357335Bw39Body weight QTL 393.3body mass (VT:0001259)body weight (CMO:0000012)1197814409242814409Rat
1578780Cm52Cardiac mass QTL 523.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)181591954219808434Rat
1302787Stl25Serum triglyceride level QTL 252.70.0073blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)1180359209210702199Rat
1549830Bss1Bone structure and strength QTL 14.8femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)1172609619217609619Rat
7794788Mcs32Mammary carcinoma susceptibility QTL 322.61mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)1115540693238914717Rat
70163Bw20Body weight QTL 205.1body mass (VT:0001259)body weight (CMO:0000012)1174133260219133260Rat
1578763Kidm29Kidney mass QTL 293.30.0001kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1179567751260522016Rat
631838Niddm36Non-insulin dependent diabetes mellitus QTL 360.01insulin secretion trait (VT:0003564)calculated pancreatic islet insulin release measurement (CMO:0001217)1184550676229550676Rat
1549837Hcar15Hepatocarcinoma resistance QTL 150.05liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1153136852260522016Rat
4889428Stresp24Stress response QTL 240.05heart pumping trait (VT:2000009)absolute change in electrocardiographic low frequency R-R spectral component to high frequency R-R spectral component ratio (CMO:0002162)1155866514200866514Rat
1578759Uae30Urinary albumin excretion QTL 303.30.003urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1150700247252085048Rat
2300161Bmd43Bone mineral density QTL 438.40.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)1171629477216629477Rat
1358898Bp255Blood pressure QTL 2553.6arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1191019702246062233Rat
731168Bp154Blood pressure QTL 1543.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)194642644214537671Rat
2300175Bmd40Bone mineral density QTL 4015.40.0001femur mineral mass (VT:0010011)bone mineral density (CMO:0001226)1201554356246554356Rat
2300174Bmd42Bone mineral density QTL 428.40.0001lumbar vertebra mineral mass (VT:0010511)bone mineral density (CMO:0001226)1171629477216629477Rat
737828Hcas3Hepatocarcinoma susceptibility QTL 34.9liver integrity trait (VT:0010547)liver tumorous lesion volume to total liver volume ratio (CMO:0001082)1144267353222987745Rat
1358886Bp260Blood pressure QTL 2603.67arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1151162766225824951Rat
724531Uae5Urinary albumin excretion QTL 54urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)1150700142252085212Rat
2300187Bmd41Bone mineral density QTL 418.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)1171629477216629477Rat
2314011Gluco56Glucose level QTL 56blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1199773958202166723Rat
8552891Epfw5Epididymal fat weight QTL 54.4epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)1193113876238113876Rat
1354580Scort1Serum corticosterone level QTL 13.4blood corticosterone amount (VT:0005345)blood corticosterone level (CMO:0001172)1156677124256448636Rat
724559Pancm1Pancreatic morphology QTL 17.1islet of Langerhans morphology trait (VT:0005215)pancreatic islet damage composite score (CMO:0001156)1181759564214537555Rat
1354591Cm36Cardiac mass QTL 364.1heart left ventricle mass (VT:0007031)calculated heart weight (CMO:0000073)1102813953201278233Rat
619613Bp77Blood pressure QTL 770.01arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)1164747424209747424Rat
2312564Glom18Glomerulus QTL 182.40.003kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)1185356336231689108Rat
724562Rends1Renal damage susceptibility QTL 10.05kidney glomerulus integrity trait (VT:0010546)index of glomerular damage (CMO:0001135)1169537671214537671Rat
1331790Bp201Blood pressure QTL 2013.127arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1198211513225126682Rat
1354615Cm32Cardiac mass QTL 325.2heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)1102813953201278233Rat
631658Cm7Cardiac mass QTL 75.320.0001aorta mass (VT:0002845)aorta weight (CMO:0000076)1196248093241248093Rat
1600380Niddm70Non-insulin dependent diabetes mellitus QTL 703.10.0008blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)1176550523221550523Rat
1354610Bw34Body weight QTL 344.1body mass (VT:0001259)body weight (CMO:0000012)1151162512256448636Rat
1582206Kidm33Kidney mass QTL 336.9kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)1188377360224054420Rat
1354620Kidm19Kidney mass QTL 194kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1151162512201278233Rat
8655855Arrd3Age-related retinal degeneration QTL 33.07lens clarity trait (VT:0001304)cataract incidence/prevalence measurement (CMO:0001585)1183970203243914901Rat
1354618Kidm15Kidney mass QTL 155kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)1156677124201278233Rat
6903303Scl34Serum cholesterol QTL 342.50.0033blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)1180359209218108781Rat
1600374Mcs17Mammary carcinoma susceptibility QTL 173mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)1197670404242670404Rat
2293083Iddm25Insulin dependent diabetes mellitus QTL 254.18blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1181829673224569684Rat
1354606Bp246Blood pressure QTL 2463.6arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)1102813953218753816Rat
1358191Ept10Estrogen-induced pituitary tumorigenesis QTL 103.8pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)1192825253243914732Rat
1354602Bw35Body weight QTL 3512.2body mass (VT:0001259)body weight (CMO:0000012)1151162512201278233Rat
1354646Kidm18Kidney mass QTL 185.7kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1151162512256448636Rat
2302375Bw83Body weight QTL 834.870.0002body mass (VT:0001259)body weight (CMO:0000012)1197697768242697768Rat
1354652Kidm20Kidney mass QTL 204.3kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1177227632256448636Rat
2293674Bss39Bone structure and strength QTL 397.10.0001femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)1201554356246554356Rat
2302378Insul11Insulin level QTL 113.25blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1144267353251128347Rat
1354653Despr9Despair related QTL 90.00019locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)1167909849212909849Rat
2293673Bss27Bone structure and strength QTL 2718.630.0001femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)1171629477216629477Rat
2293677Bss41Bone structure and strength QTL 419.380.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra cross-sectional area (CMO:0001689)1171629477216629477Rat
1600395Niddm69Non-insulin dependent diabetes mellitus QTL 694.140.0002blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)1195804352257091168Rat
1354624Cm35Cardiac mass QTL355.7heart left ventricle mass (VT:0007031)calculated heart weight (CMO:0000073)1177227632256448636Rat
1600396Niddm68Non-insulin dependent diabetes mellitus QTL 684.970.0003blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1195804352257091168Rat
1558658Bw59Body weight QTL 593.50.0003body mass (VT:0001259)body weight (CMO:0000012)1178784622223784622Rat
1354636Lmblg1Limb length QTL 16.4tibia length (VT:0004357)tibia length (CMO:0000450)1151162512201278233Rat
2293689Bss47Bone structure and strength QTL 477.250.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra trabecular cross-sectional area (CMO:0001692)1171629477216629477Rat
1600388Niddm67Non-insulin dependent diabetes mellitus QTL 675.840.000004blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1195804352257091168Rat
2293694Bss38Bone structure and strength QTL 387.050.0001femur strength trait (VT:0010010)femur stiffness (CMO:0001674)1201554356246554356Rat
1598853Memor3Memory QTL 34.5exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)1143506580212458660Rat
61341Bp26Blood pressure QTL 26arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1169537671214537671Rat
1354634Kidm12Kidney mass QTL 123.9kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)1151162512201278233Rat
2293693Bss22Bone structure and strength QTL 2233.520.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)1171629477216629477Rat
1300145Rf7Renal function QTL 72.96urine creatinine amount (VT:0010540)urine creatinine level (CMO:0000125)1185145134221264292Rat
61347Bp197Blood pressure QTL 1974.2arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)1158633083203633083Rat
8655655Arrd2Age-related retinal degeneration QTL 27.79retinal layer morphology trait (VT:0003727)percentage of study population developing retinopathy during a period of time (CMO:0002453)1183970203243914901Rat
631214Bw61Body weight QTL613.40.0001intramuscular adipose amount (VT:0010044)intramuscular fat area (CMO:0001162)1173108781218108781Rat
7771612Cm80Cardiac mass QTL 808.4heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)1149448574221264292Rat
1354661Bw33Body weight QTL 335.2body mass (VT:0001259)body weight (CMO:0000012)1151162512256448636Rat
737977Bp160Blood pressure QTL 1600.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1181133855226133855Rat
2293654Bss30Bone structure and strength QTL 3032.650.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1171629477216629477Rat
2293655Bss36Bone structure and strength QTL 3610.660.0001femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)1201554356246554356Rat
1298084Thym4Thymus enlargement QTL 410.68thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)1197814409242814409Rat
1359018Hrtrt20Heart rate QTL 203.08heart pumping trait (VT:2000009)heart rate (CMO:0000002)1185356336202902618Rat
1358292Cm37Cardiac mass QTL 376.28e-07heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)1196248093241248093Rat
61376Bp42Blood pressure QTL 4223.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1197814409242814409Rat
634313Niddm43Non-insulin dependent diabetes mellitus QTL 43blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1199050459259647894Rat
634312Bp143Blood pressure QTL 14330.0002arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1182623426219932796Rat
1358294Bw37Body weight QTL 3750.000011body mass (VT:0001259)body weight (CMO:0000012)1171310381216310381Rat
2312420Pur17Proteinuria QTL 177.10.0001urine protein amount (VT:0005160)urine total protein excretion rate (CMO:0000756)1156677124218753816Rat
10059600Bp378Blood pressure QTL 3783.080.05arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1176869060221869060Rat
7421630Bp362Blood pressure QTL 3620.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1118608292241799120Rat
634321Hc1Hypercalciuria QTL 12.91urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)1178810256240830002Rat
2292218Kidm35Kidney mass QTL 35kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)1199368955224569684Rat
10059587Bw173Body weight QTL 1733.230.025body mass (VT:0001259)body weight (CMO:0000012)1202069611247069611Rat
2292222Bp307Blood pressure QTL 3073.060.0014arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1164310393213533942Rat
2292220Bp306Blood pressure QTL 3063.470.00087arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1164310393243914901Rat
10059590Kidm44Kidney mass QTL 443.420.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)1191033875236033875Rat
1641926Teswt2Testicular weight QTL 22.82testis mass (VT:1000644)both testes wet weight (CMO:0000175)1197697768238755659Rat
6480773Gluco64Glucose level QTL 645.09blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1199050459200611765Rat
634338Hcar4Hepatocarcinoma resistance QTL 44.6liver integrity trait (VT:0010547)liver tumorous lesion number to liver area ratio (CMO:0001210)1193422268214537671Rat
6480783Insul19Insulin level QTL 194.33blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)1197489281200611765Rat
6480780Insul18Insulin level QTL 184.11blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)1189607473200611765Rat
631549Bp89Blood pressure QTL 895.7arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1123350581201284552Rat
738032Hcas5Hepatocarcinoma susceptibility QTL 53.12liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1176426412257976495Rat
7394701Uae46Urinary albumin excretion QTL 463.60.0056urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1201554356246554356Rat


Additional Information

RGD Curation Notes
Note Type Note Reference
qtl_general number of animals used: 515 males from the first 4 generations of breeding 2316693
qtl_general sharp peak for expression of Tpcn2 was observed, there was a nonsynonymous amino acid change in F344, this negatively correlates to fasting glucose 9587420