Insul19 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL: Insul19 (Insulin level QTL 19) Rattus norvegicus

Symbol: Insul19
Name: Insulin level QTL 19
RGD ID: 6480783
Also known as: QUICKI
Trait: blood insulin amount   (VT:0001560)    
Measurement Type: plasma insulin level   (CMO:0000342)    
LOD Score: 4.33
P Value: Not Available
Variance: Not Available
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21197,489,281 - 200,611,765RGD_MAPPER_PIPELINE
Rnor_6.01215,494,321 - 218,614,387RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01218,337,839 - 225,482,294RGDRnor5.0
RGSC_v3.41198,853,034 - 205,897,680RGDRGSC3.4
Cross Type: Not Available
Strains Crossed: NMcwi:HS 
JBrowse: View Region in Genome Browser (JBrowse)
Model



Candidate Gene Status
Tpcn2 is a candidate Gene for Insul19

Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

Experimental Condition
fasting  (IDA)

Measurement Method

Vertebrate Trait

Rat Strain
NMcwi:HS  (IEA)

References


Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
1563319Ifitm10interferon induced transmembrane protein 101215521604215538283Rat
621511Ctsdcathepsin D1215541570215553446Rat
7552934LOC102546801uncharacterized LOC1025468011215589018215601471Rat
68399Syt8synaptotagmin 81215605408215607602Rat
62050Tnni2troponin I2, fast skeletal type1215609110215611652Rat
1306133Lsp1lymphocyte-specific protein 11215628750215662505Rat
1592568Prr33proline rich 331215658996215666512Rat
3883Tnnt3troponin T3, fast skeletal type1215666628215683628Rat
68343Mrpl23mitochondrial ribosomal protein L231215701544215709313Rat
7672242LOC102547298uncharacterized LOC1025472981215722314215727978Rat
2775H19H19, imprinted maternally expressed transcript (non-protein coding)1215744404215747080Rat
2314883Mir675microRNA 6751215745981215746064Rat
7730578LOC102547221uncharacterized LOC1025472211215747162215753871Rat
7669488LOC102548505uncharacterized LOC1025485051215753880215801652Rat
2870Igf2insulin-like growth factor 21215828102215839081Rat
2314879Mir483microRNA 4831215832088215832160Rat
6501977LOC100909737uncharacterized LOC1009097371215838112215844406Rat
7711326LOC102548568vegetative cell wall protein gp1-like1215844598215847533Rat
2916Ins2insulin 21215856967215858034Rat
7585225LOC102549750uncharacterized LOC1025497501215881009215939811Rat
11378084LOC108349673uncharacterized LOC1083496731215986859215989549Rat
3853Thtyrosine hydroxylase1216073034216080287Rat
2159Ascl2achaete-scute family bHLH transcription factor 21216154002216156409Rat
7692070LOC102549151uncharacterized LOC1025491511216178799216184565Rat
1308721Tspan32tetraspanin 321216189535216206202Rat
7577477LOC102550186uncharacterized LOC1025501861216230707216236566Rat
2315Cd81Cd81 molecule1216237663216253460Rat
1307043Tssc4tumor suppressing subtransferable candidate 41216253786216256610Rat
1310620Trpm5transient receptor potential cation channel, subfamily M, member 51216256653216281504Rat
621503Kcnq1potassium voltage-gated channel subfamily Q member 11216293087216630339Rat
727892Cdkn1ccyclin-dependent kinase inhibitor 1C1216661067216663791Rat
1303323Slc22a18solute carrier family 22, member 181216676330216700632Rat
1304755Phlda2pleckstrin homology-like domain, family A, member 21216701345216704479Rat
1305391Nap1l4nucleosome assembly protein 1-like 41216715352216751742Rat
1310747Carscysteinyl-tRNA synthetase1216759367216801652Rat
1309693Tnfrsf26tumor necrosis factor receptor superfamily, member 261216808642216829361Rat
1586688Tnfrsf22tumor necrosis factor receptor superfamily, member 221216845789216859606Rat
1308402Osbpl5oxysterol binding protein-like 51216866263216920625Rat
9445960LOC103691270uncharacterized LOC1036912701216934099216936936Rat
1562011RGD1562011similar to MAS-related G-protein coupled receptor, member G1216941913216942791Rat
738044MrgprgMAS related GPR family member G1216952942216955673Rat
738045MrgpreMAS related GPR family member E1216969464216973936Rat
727801Nadsyn1NAD synthetase 11216985710217013743Rat
621769Dhcr77-dehydrocholesterol reductase1217018916217034890Rat
7506405LOC102552318actin-like1217039727217066768Rat
628772Shank2SH3 and multiple ankyrin repeat domains 21217149156217593950Rat
11459734LOC10834967460S ribosomal protein L21 pseudogene1217157580217159437Rat
619839Cttncortactin1217602698217638196Rat
1309009Ppfia1PTPRF interacting protein alpha 11217644259217721285Rat
11497536LOC10834967660S ribosomal protein L7a pseudogene1217687271217688236Rat
2324580LOC100364769LRRG00136-like1217699180217735742Rat
628700FaddFas associated via death domain1217746176217748581Rat
1310786Ano1anoctamin 11217754349217902540Rat
11484604LOC108349677uncharacterized LOC1083496771217930453217933849Rat
620126Fgf3fibroblast growth factor 31218003018218006942Rat
11455008LOC108349678uncharacterized LOC1083496781218007765218020101Rat
620127Fgf4fibroblast growth factor 41218024537218029539Rat
620166Fgf19fibroblast growth factor 191218058405218061693Rat
2193Bc1brain cytoplasmic RNA 11218075359218075511Rat
1304637Lto1LTO1 maturation factor of ABCE11218075995218082700Rat
9441275LOC10369127140S ribosomal protein S10 pseudogene1218084336218087286Rat
68384Ccnd1cyclin D11218090750218100447Rat
11418059LOC108349679uncharacterized LOC1083496791218227882218233736Rat
628800Smim38small integral membrane protein 381218369204218374619Rat
1311779Tpcn2two pore segment channel 21218419182218448902Rat
708478MrgprfMAS related GPR family member F1218465642218476228Rat
738040MrgprdMAS related GPR family member D1218481146218491910Rat
68325Ighmbp2immunoglobulin mu DNA binding protein 21218509274218531922Rat
1310203Mrpl21mitochondrial ribosomal protein L211218532045218545428Rat
2396Cpt1acarnitine palmitoyltransferase 1A1218568157218629679Rat

Markers in Region
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolExpected SizeChrStartStopSpeciesMatch
10768D1Wox221301215830072215830192Ratregion
10769D1Arb242591215830001215830265Ratregion
33878D1Mit271951216213318216213510Ratregion
34244D1Mgh101381217054291217054418Ratregion
11413D1Smu31011216082612216082712Ratregion
11435D1Arb233001215669977215670289Ratregion
33753D1Mit51651215711860215712024Ratregion
35204D1Rat3671601215920148215920314Ratregion
35204D1Rat3671601215912432215912582Ratregion
35615D1Rat701521217776868217776984Ratregion
38854D1Rat1682091217372257217372467Ratregion
38954D1Rat1812161215684498215684711Ratregion
42524D1Rat3662001215726311215726510Ratregion
43377D1Wox91131216325697216325819Ratregion
43379D1Got1842151217466279217466493Ratregion
43381D1Got1851441217054320217054463Ratregion
43384D1Got1892641218614124218614387Ratregion
43388D1Got1901731218411277218411450Ratregion
629602D1Hmgc82811215830042215830306Ratregion
1631819D1Wox591471218093299218093445Ratregion
1627045D1Mco271731215830025215830197Ratregion
1641445D1Wox581761215830069215830244Ratregion
1632933D1Cebr31211218399206218399326Ratregion
1635093D1Got3581841216698339216698522Ratregion
1635610D1Got3701501216878811216878955Ratregion
1635784D1Wox552041215669550215669753Ratregion
1637095D1Wox812071217590876217591082Ratregion
7206000Ccnd11831218098529218100102Ratregion
7204417H195311215744502215745143Ratregion
7204418Igf25181215830739215831481Ratregion
7192170Nap1l42051216737405216737773Ratregion
7192850H196831215746376215747058Ratregion
7192852H191481215744552215744699Ratregion
7192868Igf23301215831006215831560Ratregion
7192870Igf26071215830923215831529Ratregion
7192874Ins21241215857020215857143Ratregion
7192878Kcnq101216293482216293521Ratregion
7192880Kcnq101216370232216370271Ratregion
7192882Kcnq101216335834216335873Ratregion
7192884Kcnq11441216629197216629340Ratregion
7192536D1Mgh221501215830050215830199Ratregion
7192481Ins13121215857029215857839Ratregion
5035799PMC18740P14091216074286216074694Ratregion
5035833PMC21231P13011215857051215857850Ratregion
5035835PMC21334P12291215857069215857796Ratregion
5035915PMC307617P11981216661551216661748Ratregion
5036111UniSTS:1413112121216661509216661720Ratregion
7206676Tnnt32381215679680215680133Ratregion
5036332H192001215744502215744701Ratregion
5036386Kcnq1921216378790216379969Ratregion
5036406UniSTS:1438302571216155756216156012Ratregion
5036424Nap1l401216715428216715596Ratregion
5036927AU0496501361218480671218480808Ratregion
5031268PMC123023P17071215857117215857823Ratregion
7206114UniSTS:53213801215830431215831014Ratregion
7206116UniSTS:5321392251215831207215832873Ratregion
7206120UniSTS:5321568081216702616216703423Ratregion
7206130UniSTS:5321681341215745481215745614Ratregion
7206132Cdkn1c01216661906216662616Ratregion
5026576RH1327421921215659030215659221Ratregion
5034508BI2801172201218092097218092316Ratregion
5029425Huc11931215758634215758826Ratregion
5027050RH1345412011218090898218091098Ratregion
5032599RH1345991971215521719215521915Ratregion
5030131BE09886701215829335215829490Ratregion
5030159BF3891631231216433507216433629Ratregion
5025042AW7424462491215828548215828796Ratregion
5027801RH947943601215828886215829246Ratregion
5025488RH1285142191216951934216952152Ratregion
5033621RH1394952131218509062218509274Ratregion
5028482M692001041216073109216073212Ratregion
5031131AA9642101531216440655216440807Ratregion
5051857RH946981341216077932216078065Ratregion
5052029RH947982591215857853215858111Ratregion
5052031RH947993001215857071215857869Ratregion
5051437AI4625381041216866279216866382Ratregion
5057183D1Bda445351215857502215858036Ratregion
5057181D1Bda433131215541817215542129Ratregion
5057428BF4183841861216230793216230978Ratregion
5057876BF3862971941216713912216714105Ratregion
5057223D1Bda703111216154061216154371Ratregion
5050398RH1340332131216630124216630336Ratregion
5057688BF3925921301215528770215528899Ratregion
5050124RH1338761801218093508218093687Ratregion
5052472M903161051215662284215662388Ratregion
5052633RH1421742141218474465218474678Ratregion
5051018RH1343901931217644361217644553Ratregion
5050368RH1340161881216776198216776385Ratregion
5051719RH946181781216253130216253307Ratregion
5040666RH1284141841215744454215744637Ratregion
5044654RH1307281961216950454216950639Ratregion
5044654RH1307281961216941112216941307Ratregion
5044104RH1304122201216702808216703325Ratregion
5044546RH1306651971216256261216256457Ratregion
5047946RH1326202101216759460216759669Ratregion
5046948RH1320471961217035513217035708Ratregion
5039478RH1277282171216253132216253348Ratregion
5039504RH1277432011217745456217745656Ratregion
5040038RH1280542101217034526217034735Ratregion
5040590RH1283702171215828282215828498Ratregion
7192429Osbpl54171216866949216867365Ratregion
7193045Fgf411471218026056218027202Ratregion
7193046Ins19721215857064215858035Ratregion
7204413Igf22551215831200215832896Ratregion
5074610RH1381161401217344812217344951Ratregion
5077568RH1398312051215670766215670970Ratregion
5079328RH1409191901215662313215662502Ratregion
5078684RH1404891221216715438216715559Ratregion
5073598RH1375281331215979322215979454Ratregion
5070668RH1346351891216866309216866505Ratregion
5072938RH1371411901215662282215662471Ratregion
5072942RH1371432191216205980216206198Ratregion
5071330RH1350202151216169030216169244Ratregion
5072470RH1368682191218082432218082650Ratregion
5067736AU0475672611216407652216407907Ratregion
5068116AU0473381341216555699216555832Ratregion
5070295RH945851831215837378215837560Ratregion
5060066BI2859961991216665418216665616Ratregion
5060186BI2796601611216777210216777370Ratregion
5060536BE0983171201216808792216808911Ratregion
5062406BE1066482071218198014218198220Ratregion
5065886AA9643061281218476047218476174Ratregion
5063128BI2959351551216968048216968202Ratregion
5066310PMC151031P19211216077249216078169Ratregion
5066350PMC15822P16161215610647215611262Ratregion
5061424BF3963901251215881074215881198Ratregion
5084182AA7994651081216183776216184144Ratregion
5087912UniSTS:1432962881215744405215744692Ratregion
5088032Slc22a1l1911216678164216678354Ratregion
5082999BF3906001501216172388216172537Ratregion
5087362AW5323611741215517400215517573Ratregion
5087462PMC187562P13911216663654216664044Ratregion
5089891AU0494251291216460860216460988Ratregion
5088130Tssc301216703468216703507Ratregion
5081503BF4201422161216642722216642937Ratregion
5087181AA8008861881217644368217644555Ratregion
5088473AU0485901251218492455218492579Ratregion
5082859BF3902961501218512660218512809Ratregion
5083523BF3916721181217593718217593835Ratregion
5503029MARC_54883-54884:1155673702:101216663137216663721Ratregion
5503476UniSTS:4626872541215857030215857782Ratregion
5503625UniSTS:4653962971216480009216480305Ratregion
5503625UniSTS:4653962971216473690216473986Ratregion
5507537REN1159132601215606262215606521Ratregion
5507606Ccnd11671218093597218095194Ratregion
5507608Cdkn1c01216661970216662960Ratregion
5503652UniSTS:4654725081218092102218092609Ratregion
5507610Cdkn1c6041216662593216663196Ratregion
5507658AA24195801216255917216255955Ratregion
5503603UniSTS:4647855731218026593218027165Ratregion
5503629UniSTS:4653982571216715648216715904Ratregion
5503756UniSTS:47055201216662836216663611Ratregion
5504564PMC305633P12681217746238217746505Ratregion
5504618PMC316622P13881215755418215755805Ratregion
5504642PMC321442P22061218097768218098512Ratregion
5504989Cdkn1c1511216661569216661719Ratregion
5504994Cdkn1c7461216661242216661987Ratregion
5504774PMC98458P12001218099948218100147Ratregion
5504953Phlda201216702610216703302Ratregion
5504991Cdkn1c01216661959216662610Ratregion
5505071Cdkn1c1931216662768216662960Ratregion
5505130Cdkn1c01216661958216662611Ratregion
5505887UniSTS:4960014881216274354216274841Ratregion
5506513UniSTS:276141851215832832215832916Ratregion
5501730UniSTS:2670032181215857029215857745Ratregion
550015702.MMHAP94FRA8.seq6631218392556218393218Ratregion
5499965UniSTS:2358162001216154027216154226Ratregion
5499897UniSTS:23534001216870404216871743Ratregion
5500479Osbp2-pending9991216884375216885373Ratregion
5500501RH1265962101217602766217602975Ratregion
5501199PMC153767P22131215857122215857833Ratregion
5501544D8S51212741216210569216211842Ratregion
5501019PMC123023P33321215857028215857858Ratregion
5501171PMC151856P11161215831188215831528Ratregion
5501339ECD217422331215835624215835856Ratregion
5501389Ascl22371216155166216155402Ratregion
5501453Th11301216077097216078226Ratregion
5501644UniSTS:2654591631215744537215744699Ratregion
5503896Osbpl59941216884375216885368Ratregion
5504584PMC309645P22561215846479215846734Ratregion
5505020Igf21341215831575215832925Ratregion
5501650UniSTS:2654866051216662592216663196Ratregion
5501652UniSTS:2654912511215744854215745215Ratregion
5501654UniSTS:2654926071215744450215745167Ratregion
5501657PMC24644P61881215857034215857720Ratregion
5506191UniSTS:4987568791215541851215543158Ratregion
5502226Fgf411781218026020218027197Ratregion
12790683rs6530962301218387917218387917Ratregion
Position Markers

Flank 1: (D1Rat129)
Rat AssemblyChrPosition (strand)Source
Rnor_5.01218,337,839 - 218,338,087NCBI
RGSC_v3.41198,853,034 - 198,853,281RGD
RGSC_v3.11199,003,017 - 199,003,326RGD
RH 3.4 Map11437.9UniSTS
RH 3.4 Map11437.9RGD
SHRSP x BN Map1101.4699RGD
SHRSP x BN Map1101.4699UniSTS
Peak: (D1Mgh10)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21199,050,459 - 199,050,587 (+)MAPPER
Rnor_6.01217,054,291 - 217,054,418NCBI
Rnor_5.01223,910,550 - 223,910,677UniSTS
RGSC_v3.41204,280,278 - 204,280,406RGD
RGSC_v3.41204,280,279 - 204,280,406UniSTS
RGSC_v3.11204,433,664 - 204,433,956RGD
Celera1196,613,223 - 196,613,350UniSTS
RH 2.0 Map11099.1RGD
Flank 2: (D1Got189)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21200,611,501 - 200,611,765 (+)MAPPER
Rnor_6.01218,614,124 - 218,614,387NCBI
Rnor_5.01225,482,031 - 225,482,294UniSTS
RGSC_v3.41205,897,416 - 205,897,680RGD
RGSC_v3.41205,897,417 - 205,897,680UniSTS
RGSC_v3.11206,050,870 - 206,051,133RGD
Celera1198,166,955 - 198,167,218UniSTS
RH 3.4 Map11560.5UniSTS
RH 3.4 Map11560.5RGD
RH 2.0 Map11113.7RGD
Cytogenetic Map1q43UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2292218Kidm35Kidney mass QTL 35kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)1217372257244992610Rat
70209Niddm23Non-insulin dependent diabetes mellitus QTL 232.82blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)199983293216325819Rat
619613Bp77Blood pressure QTL 770.01arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)1175447029220447029Rat
619613Bp77Blood pressure QTL 770.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1175447029220447029Rat
631205Bp196Blood pressure QTL 19640.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1126240667217054291Rat
631214Bw61Body weight QTL613.40.0001intramuscular adipose amount (VT:0010044)intramuscular fat area (CMO:0001162)1193220385238220385Rat
2302375Bw83Body weight QTL 834.870.0002body mass (VT:0001259)body weight (CMO:0000012)1215711860260711860Rat
2302378Insul11Insulin level QTL 113.25blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1156446196274977688Rat
631260Tcas2Tongue tumor susceptibility QTL 24.93tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)1210019247217054418Rat
70163Bw20Body weight QTL 205.1body mass (VT:0001259)body weight (CMO:0000012)1189514504234514504Rat
724531Uae5Urinary albumin excretion QTL 54urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)1161321152273792054Rat
724559Pancm1Pancreatic morphology QTL 17.1islet of Langerhans morphology trait (VT:0005215)pancreatic islet damage composite score (CMO:0001156)1198585664236763415Rat
724562Rends1Renal damage susceptibility QTL 10.05kidney glomerulus integrity trait (VT:0010546)index of glomerular damage (CMO:0001135)1137787261236763528Rat
1331749Hrtrt11Heart rate QTL 112.973heart pumping trait (VT:2000009)heart rate (CMO:0000002)199983293216213510Rat
737828Hcas3Hepatocarcinoma susceptibility QTL 34.9liver integrity trait (VT:0010547)liver tumorous lesion volume to total liver volume ratio (CMO:0001082)1156446196243311614Rat
1298084Thym4Thymus enlargement QTL 410.68thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)1215828102260828102Rat
631658Cm7Cardiac mass QTL 75.320.0001aorta mass (VT:0002845)aorta weight (CMO:0000076)1216324817261324817Rat
737977Bp160Blood pressure QTL 1600.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1197963658242963658Rat
1331790Bp201Blood pressure QTL 2013.127arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1216213318245529710Rat
1354580Scort1Serum corticosterone level QTL 13.4blood corticosterone amount (VT:0005345)blood corticosterone level (CMO:0001172)1167394665278228889Rat
1582206Kidm33Kidney mass QTL 336.9kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)1205603081244401301Rat
731168Bp154Blood pressure QTL 1543.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1100131562236763528Rat
738032Hcas5Hepatocarcinoma susceptibility QTL 53.12liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1191825895279986079Rat
631549Bp89Blood pressure QTL 895.7arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1130779320219238476Rat
1302787Stl25Serum triglyceride level QTL 252.70.0073blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)1197187728230420772Rat
1641926Teswt2Testicular weight QTL 22.82testis mass (VT:1000644)both testes wet weight (CMO:0000175)1215711860258765521Rat
1598853Memor3Memory QTL 34.5exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)1153834077232297227Rat
2300161Bmd43Bone mineral density QTL 438.40.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)1189170900234170900Rat
2300174Bmd42Bone mineral density QTL 428.40.0001lumbar vertebra mineral mass (VT:0010511)bone mineral density (CMO:0001226)1189170900234170900Rat
2300187Bmd41Bone mineral density QTL 418.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)1189170900234170900Rat
2293654Bss30Bone structure and strength QTL 3032.650.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1189170900234170900Rat
2293673Bss27Bone structure and strength QTL 2718.630.0001femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)1189170900234170900Rat
2293677Bss41Bone structure and strength QTL 419.380.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra cross-sectional area (CMO:0001689)1189170900234170900Rat
2293689Bss47Bone structure and strength QTL 477.250.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra trabecular cross-sectional area (CMO:0001692)1189170900234170900Rat
2293693Bss22Bone structure and strength QTL 2233.520.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)1189170900234170900Rat
631838Niddm36Non-insulin dependent diabetes mellitus QTL 360.01insulin secretion trait (VT:0003564)calculated pancreatic islet insulin release measurement (CMO:0001217)1205195290250195290Rat
634312Bp143Blood pressure QTL 14330.0002arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1198446729240017341Rat
634313Niddm43Non-insulin dependent diabetes mellitus QTL 43blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1217054291281795785Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)149578693217054291Rat
634321Hc1Hypercalciuria QTL 12.91urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)1193968438261264776Rat
634338Hcar4Hepatocarcinoma resistance QTL 44.6liver integrity trait (VT:0010547)liver tumorous lesion number to liver area ratio (CMO:0001210)1210960636236763528Rat
1357335Bw39Body weight QTL 393.3body mass (VT:0001259)body weight (CMO:0000012)1215828102260828102Rat
1600363Hc6Hypercalciuria QTL 62.7urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)1195598053265002735Rat
1600374Mcs17Mammary carcinoma susceptibility QTL 173mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)1215684498260684498Rat
1600380Niddm70Non-insulin dependent diabetes mellitus QTL 703.10.0008blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)1194554354239554354Rat
1600388Niddm67Non-insulin dependent diabetes mellitus QTL 675.840.000004blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1213476630278978026Rat
1600395Niddm69Non-insulin dependent diabetes mellitus QTL 694.140.0002blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)1213476630278978026Rat
1600396Niddm68Non-insulin dependent diabetes mellitus QTL 684.970.0003blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1213476630278978026Rat
1578759Uae30Urinary albumin excretion QTL 303.30.003urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1161321256273791893Rat
1578763Kidm29Kidney mass QTL 293.30.0001kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1196395041282763074Rat
1578778Pur4Proteinuria QTL 43.30.003total urine protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)1161321256273791893Rat
1578780Cm52Cardiac mass QTL 523.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)182788437239853971Rat
1300145Rf7Renal function QTL 72.96urine creatinine amount (VT:0010540)urine creatinine level (CMO:0000125)1201146802241482368Rat
1354591Cm36Cardiac mass QTL 364.1heart left ventricle mass (VT:0007031)calculated heart weight (CMO:0000073)1108986301219232156Rat
1354602Bw35Body weight QTL 3512.2body mass (VT:0001259)body weight (CMO:0000012)1161784169219232156Rat
1354606Bp246Blood pressure QTL 2463.6arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)1108986301238830534Rat
1354610Bw34Body weight QTL 344.1body mass (VT:0001259)body weight (CMO:0000012)1161784169278228889Rat
1354615Cm32Cardiac mass QTL 325.2heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)1108986301219232156Rat
1354618Kidm15Kidney mass QTL 155kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)1167394665219232156Rat
1354620Kidm19Kidney mass QTL 194kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1161784169219232156Rat
1354624Cm35Cardiac mass QTL355.7heart left ventricle mass (VT:0007031)calculated heart weight (CMO:0000073)1192639698278228889Rat
1354634Kidm12Kidney mass QTL 123.9kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)1161784169219232156Rat
1354636Lmblg1Limb length QTL 16.4tibia length (VT:0004357)tibia length (CMO:0000450)1161784169219232156Rat
1354646Kidm18Kidney mass QTL 185.7kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1161784169278228889Rat
1354652Kidm20Kidney mass QTL 204.3kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1192639698278228889Rat
1354653Despr9Despair related QTL 90.00019locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)1185390068230390068Rat
1354661Bw33Body weight QTL 335.2body mass (VT:0001259)body weight (CMO:0000012)1161784169278228889Rat
1359018Hrtrt20Heart rate QTL 203.08heart pumping trait (VT:2000009)heart rate (CMO:0000002)1201358068221983732Rat
1558658Bw59Body weight QTL 593.50.0003body mass (VT:0001259)body weight (CMO:0000012)1196738546241738546Rat
1549837Hcar15Hepatocarcinoma resistance QTL 150.05liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1163796316282763074Rat
1358191Ept10Estrogen-induced pituitary tumorigenesis QTL 103.8pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)1210360774264802828Rat
2292220Bp306Blood pressure QTL 3063.470.00087arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1174905700264802994Rat
2292222Bp307Blood pressure QTL 3073.060.0014arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1174905700233490237Rat
2293083Iddm25Insulin dependent diabetes mellitus QTL 254.18blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1198655722244992610Rat
2312420Pur17Proteinuria QTL 177.10.0001urine protein amount (VT:0005160)urine total protein excretion rate (CMO:0000756)1167394665238830534Rat
2312564Glom18Glomerulus QTL 182.40.003kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)1201358068252480016Rat
2314011Gluco56Glucose level QTL 56blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1217776868220128172Rat
1358886Bp260Blood pressure QTL 2603.67arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1161784422246226103Rat
1358898Bp255Blood pressure QTL 2553.6arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1208517798266948272Rat
1549830Bss1Bone structure and strength QTL 14.8femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)1190282646235282646Rat
1358292Cm37Cardiac mass QTL 376.20.00000081heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)1216324817261324817Rat
1358294Bw37Body weight QTL 3750.000011body mass (VT:0001259)body weight (CMO:0000012)1188850303233850303Rat
61341Bp26Blood pressure QTL 26arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1137787261236763528Rat
61347Bp197Blood pressure QTL 1974.2arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)1175462885220462885Rat
61348Bp30Blood pressure QTL 302.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1154337847215828102Rat
61376Bp42Blood pressure QTL 4223.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1215828102260828102Rat
6480773Gluco64Glucose level QTL 645.09blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1217054291218614387Rat
6480777Insul17Insulin level QTL 173.86blood insulin amount (VT:0001560)blood insulin level area under curve (AUC) (CMO:0000351)1215097781216213510Rat
6480780Insul18Insulin level QTL 184.11blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)1206950905218614387Rat
6480783Insul19Insulin level QTL 194.33blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)1215494321218614387Rat
6903303Scl34Serum cholesterol QTL 342.50.0033blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)1197187728238220385Rat
8655655Arrd2Age-related retinal degeneration QTL 27.79retinal layer morphology trait (VT:0003727)percentage of study population developing retinopathy during a period of time (CMO:0002453)1202571665264802994Rat
7794788Mcs32Mammary carcinoma susceptibility QTL 322.61mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)1122614824262664716Rat
7771612Cm80Cardiac mass QTL 808.4heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)1144634295241482368Rat
7421630Bp362Blood pressure QTL 3620.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1125875758262433692Rat
8552891Epfw5Epididymal fat weight QTL 54.4epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)1210652654255652654Rat
8655855Arrd3Age-related retinal degeneration QTL 33.07lens clarity trait (VT:0001304)cataract incidence/prevalence measurement (CMO:0001585)1202571665264802994Rat
10059590Kidm44Kidney mass QTL 443.420.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)1210990171255990171Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)135377692217372257Rat
10059600Bp378Blood pressure QTL 3783.080.05arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1194872362239872362Rat


Additional Information

RGD Curation Notes
Note Type Note Reference
qtl_general measurement method:at 16 weeks of age animals were fasted overnight, blood samples were collected from the tail at 15, 30, 60, and 90 min after 1 g/kg body wt glucose injection; plasma insulin level was measured by the ELISA kit; insulin resistance was measured by quantitative insulin sensitivity check index (QUICKI) 6893578
qtl_general number of animals used: 10-21 male rats from the founders and 782 male NMcwi:HS rats 6893578
qtl_general software used:ANOVA 6893578
qtl_general sharp peak for expression of Tpcn2 was observed, there was a nonsynonymous amino acid change in F344, this negatively correlates to fasting glucose 9587420
qtl_map 204.38-204 Mb 6893578